... pressure signals during inspiration and expiration and the timing comparison of early and late expiration and is used as a non-invasive measure of bronchoconstriction is defined as the tidal flow ... challenge and lung function parameters determined by invasive lung function measurements and the technique has been widely used [18,36-39] Based on this early work and because of the convenient handling ... exact magnitude and localization of bronchoconstriction Page of 10 (page number not for citation purposes) Respiratory Research 2007, 8:63 bronchoconstrictors In 1988 Martin et al demonstrated the...
Ngày tải lên: 12/08/2014, 15:21
... medication to adult patients on Available online http://ccforum.com/content/13/6/R200 Figure (a) (b) The pulmonary delivery drug system (a) Clinical in the 'on- vent configuration' and (b) with the hand-held ... Available online http://ccforum.com/content/13/6/R200 Amikacin was monitored using the specific fragmentation reactions produced under electronspray ionization - mass spectrometry (ESI-MS)/MS conditions ... overestimation of its concentration in BAL fluids and hence VELF Overestimating VELF would have led to underestimation of amikacin concentrations in ELF On the other hand, because of possible bronchial...
Ngày tải lên: 13/08/2014, 20:21
Báo cáo khoa học: " Erythropoietin response in critically ill mechanically ventilated patients: a prospective observational study" pot
... Transfusion thresholds and goals and mechanical ventilation management was at the discretion of the attending physician Transfusion guidelines outlined by Hebert and coworkers [12] and the American ... Pneumonia COPD Pulmonary embolus CHF/cardiac ischemia Acute renal failure APACHE, Acute Physiology and Chronic Health Evaluation; CHF, congestive heart failure; COPD, chronic obstructive pulmonary ... study and control patients A significant inverse correlation between hematocrit and EPO was found in the control patients and in the nonseptic patients without renal failure The correlation of...
Ngày tải lên: 12/08/2014, 22:21
Optimal security design and dynamic capital structure in a countinous time agency model DEMARZO & SANNIKOV
... with boundary conditions b′(W1)=-1 and rb(W1) = µ - γW1, function b enters the region where it is concave Moreover, it stays concave because a concave function can never exit this region (this can ... Frequentmonitoring contracts, Working paper, Princeton University Bolton, Patrick, and David Scharfstein, 1990, A theory of predation based on agency problems in financial contracting, American Economic ... liquidation Once we know the effect of parameters on the principal’s profit, we deduce their effect on debt and the credit line by differentiating the boundary condition rb(W1) + γW1 = µ, and on the...
Ngày tải lên: 12/01/2014, 22:16
Reproductive senescence and dynamic oviposition behaviour in insects potx
... Oviposition behaviour depending upon egg complement, host encounter rate and larval density dependence Oviposition behaviour can also depend upon the host encounter rate itself (e.g Strand and Godfray, ... senescence Discussion Rosenheim (1996) considered whether egg limitation could be a plausible outcome of the evolutionary process and concluded that indeed it could be, because natural selection cannot ... trade-os in oviposition behaviour are predicted on the basis of a dynamic state-variable model (based on the solution of Equation 3) In both cases, the parameters are m 0X05, 300 and xmax 100...
Ngày tải lên: 22/03/2014, 12:20
Báo cáo hóa học: " Research Article Distributed and Collaborative Node Mobility Management for Dynamic Coverage Improvement in Hybrid Sensor Networks" doc
... know only the existence of its Voronoi neighbors and communicate among them locally to construct the Voronoi polygon By knowing its own location, and based on the grid length (in terms of the ... 13th Annual ACM International Conference on Mobile Computing and Networking, pp 39–50, Montral, Canada, 2007 [14] A Verma, H Sawant, and J Tan, “Selection and navigation of mobile sensor nodes ... maximum base price and sends a message corresponding EURASIP Journal on Wireless Communications and Networking to the cell ID and the maximum corresponding base price Note that all the candidate cells...
Ngày tải lên: 21/06/2014, 05:20
Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx
... translation between that of the quadruped animal model and the human condition Weight distribution and ground reaction forces Weight distribution imbalance was observed in animals receiving NP alone ... (NP alone), and 65.7 ± 1.0 (NP and sTNFRII), and contralateral limb percentage stance times were 72.6 ± 0.7 (pre-operative), 69.6 ± 1.2 (sham), 71.4 ± 1.0 (NP alone), and 66.0 ±1.1 (NP and sTNFRII) ... unbalanced amongst groups: 24 left and 31 right foot trials for pre-operative, 19 left and 21 right foot trials for sham controls, 14 left and 17 right foot trials for NP alone, and 20 left and 18...
Ngày tải lên: 12/08/2014, 17:22
Dynamic performance improvement in boost and buck boost derived power electronic converters
... Discussions and Conclusions 56 CHAPTER NON-LINEAR FUNCTION CONTROLLER: A SIMPLE AND COSTEFFECTIVE ALTERNATIVE TO FLC 58 4.0 Introduction 58 4.1 Analysis of FLC Structure in Power Converter Control ... Introduction CHAPTER INTRODUCTION 1.0 Background Power electronic converters are used to control and condition the flow of electrical energy between two systems The insertion of a power electronic converter ... voltage once again Chapter Introduction depends on the selected converter topology, size and count of filter components employed, and control methods employed From the above discussion, the importance...
Ngày tải lên: 16/09/2015, 15:54
Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice ppt
... transcription initiation site for human CB1 does not correspond to any transcription initiation sites identified in the mouse CB1 gene The exon/intron organization and primary sequence of the coding and ... of the introns in the mouse and human genes are identical and the sequences at the 5¢- and 3¢-splice site junctions are conserved and correspond to splice junction consensus sequences (Fig 2B) ... corresponding sequence of the mouse CB1 gene at the intron–exon junctions and the approximate size of the intron separating the two CB1 exons is 18.4 kb The relative positions of RPA-1 and RPA-2...
Ngày tải lên: 16/03/2014, 18:20
báo cáo hóa học: " The effect of consequent exposure of stress and dermal application of low doses of chlorpyrifos on the expression of glial fibrillary acidic protein in the hippocampus of adult mice" pptx
... Excel to get the serum concentrations of corticosterone by substitution in the linear regression analysis Histomorphometric studies and estimation of GFAP expression Perfusion of the brains was ... corticosterone tracer which was a corticosteronecholinesterase conjugate The well-plates were coated with mouse monoclonal anti-rabbit IgG Corticosterone in the serum sample and the corticosterone tracer ... ANOVA, post hoc LSD) compared to the control and swim stress only group (Control s) Changes in serum corticosterone Elevation of serum corticosterone levels confirmed that forced swim stress daily...
Ngày tải lên: 20/06/2014, 00:20
báo cáo hóa học:" Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice" pot
... in vivo treatment of GnRH-Ag on serum steroid concentration and expression of steroid receptors in the ovary (Figure 2) Serum P and E concentrations of the control and GnRH-Ag treated mice are ... compared to control In vitro effects of GnRH-Ag treatment on ovarian expression of ER-a and PR proteins (Figure 6) The effect of GnRH-Ag with and without LH on ovarian expression of ER-a and PR proteins ... morphology and only a marginal increase in the ovarian expression of LH receptor and StAR proteins while no change in 3b-HSD protein expression and circulating progesterone level compared with the control...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo hóa học: " Sleep quality in mechanically ventilated patients: comparison between NAVA and PSV modes" doc
... four periods Discussion In a study where spontaneously breathing patients were conscious and under mechanical ventilation, proportions of sleep fragmentation sleep architecture and sleep quality ... their muscle tone and the mechanical response of the diaphragm is, in part, spent in the production of a mechanical distortion of the chest wall, secondary to a lack of synchronization between diaphragmatic ... intensifs, Hôpital régional d’Edmundston, réseau de santé Vitalité, Edmundston, Nouveau-Brunswick, Canada Authors’ contributions SD and PO drafted the manuscript, and PB, JPT, and PA revised the...
Ngày tải lên: 20/06/2014, 23:20
Báo cáo y học: "The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice" docx
... controls Congenic regions and incidence of sialadenitis in congenic mice and healthy controls (a) The location of the two nonobese diabetic (NOD) fragments Idd5 and Nss1 on chromosome (Chr.) and ... Nss1 region on chromosome [15] from NOD.Q onto B10.Q using the speed congenic technique [17] for eight generations and at the end intercrossed for two generations Similarly, the Idd5 region on chromosome ... yielded 238 gene sets based on Panther Biological Processes and 251 gene sets based on Panther Molecular Functions Data processing and statistical analysis The gene expression data was analyzed...
Ngày tải lên: 09/08/2014, 10:21
Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene ppt
... responded to morphine and naloxone treatment Although every mouse showed the EGFP expression in the sacral and lumbar spinal cord, only of 12 (75%) mice responded significantly to the naloxone ... Morphine hydrochloride was purchased from the National Bureau of Controlled Drugs, National Health Administration, Taipei, Taiwan Naloxone and naltrexone were purchased from Sigma-Aldrich Chemical ... 25 ± 2°C and a humidity of 55% A standard rodent diet and water were provided ad libitum The care of animals was carried out Page of in accordance with institutional and international standards...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport" doc
... excitation filter and 420-470 nm emission filter for Hoechst (nucleus), 425-475 nm excitation filter and 485-535 nm emission filter for Alexa 488, 530-585 nm excitation filter and 615∞ nm emission ... comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, referred to as GRBD HRBD, AmphoΔSU and GRBD tagged ligands, and control conditioned medium were produced by transfecting ... transporter environment and in the case of GLUT1, such changes have been shown to have a major impact on GLUT1 transporter functions [19] Regional PiT distribution in basal conditions To our knowledge,...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice" pot
... MD, Roberts JR, Leonard SS, Shi X, Antonini JM: Effects of welding fumes of differing composition and solubility on free radical production and acute lung injury and inflammation in rats Toxicol ... (Framework version 3.0.19.0) Gene Expression module v.3.0.14 Reference, hybridization control, stringency and negative control genes were checked for proper chip detection Beadarray expression data were ... diseases and disorders, molecular and cellular functions and physiological system development and functions for A/J and B6 mice and 16 weeks post-exposure to GMA-MS and -SS welding fume The range...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "An intranasal selective antisense oligonucleotide impairs lung cyclooxygenase-2 production and improves inflammation, but worsens airway function, in house dust mite sensitive mice" ppsx
... Sensitization protocol and antisense oligonucleotide (ASO) administration Sensitization protocol and antisense oligonucleotide (ASO) administration Oligonucleotide was administered intranasally one ... receptors antagonist (montelukast) on neurokinin a-induced bronchoconstriction J Allergy Clin Immunol 2003, 111:833-839 Weller CL, Collington SJ, Hartnell A, Conroy DM, Kaise T, Barker JE, Wilson MS, ... experimental conditions (d) shows a single bronchiole from a non-sensitized mouse, (e) A single bronchiole from a sensitized mouse treated with control mismatched oligonucleotides (MM), and (f) COX-2...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " Different effects of deep inspirations on central and peripheral airways in healthy and allergen-challenged mice" ppt
... inspiration in rabbits subjected to bronchial challenge J Appl Physiol 2001, 91(6):2511-2516 Skloot G, Togias A: Bronchodilation and bronchoprotection by deep inspiration and their relationship to bronchial ... patients no protection against MCh-induced bronchoconstriction [5,6] Most investigations of murine models of airway inflammation have focused on bronchial responsiveness and Page 10 of 12 (page ... Authors' contributions Conclusion In summary, we have found that presence of DI may blunt bronchoconstriction of central airways in healthy mice and in acute airway inflammation, but not when chronic...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " Equipment review: Pulmonary uptake and modes of administration of inhaled nitric oxide in mechanically-ventilated patients" ppt
... volume-control and pressure-control ventilation The NO concentration is measured at simulated midtrachea during (a) volume-control and (b) pressure-control ventilation The target NO concentration was ... of NO concentration at sites corresponding to one and two tidal volumes is much higher than a sampling sites corresponding to half and one and a half tidal volumes In addition, fluctuation of ... NO concentration which was 10 times greater than the target concentration when using continuous administration during volume-controlled ventilation In contrast, using sequential administration,...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "Enteral feeding in the critically ill: comparison between the supine and prone positions A prospective crossover study in mechanically ventilated patients" pdf
... be continued in a position other than the supine position The prone position is effective in mechanically ventilated patients to improve oxygenation and mobilisation of bronchial secretions [9] ... position and for mobilisation of bronchial secretions [10–12] As far as we know, however, no data have been published concerning gastric emptying in the prone position and the ability of continued ... the prone position was caused by vomiting in the prone position The risk for gastro-oesophageal reflux, vomiting and pulmonary aspiration have not been studied for the prone position In contrast,...
Ngày tải lên: 12/08/2014, 18:21