vitamin d deficiency and parkinsons disease

... (CYP24A1) and rs2426496 (CYP24A1) Data handling and statistical analysis Clinical data and genotypes were all transferred to a SQL 2000 database and checked for completeness, paternity, and Hardy-Weinberg ... report J.A did the clinical survey, C.B did the SNP analysis, M.B built serum and DNA bank and did the vitamin D assays together with E.A who supervised also laboratory work and did functional ... organized the first part of the study, G Schlenvoigt and L.Jaeger did the IgE determination and G Fischer supervised data entry T Illig (former T.Immervoll), P Lichtner and J Heinrich supported the

Ngày tải lên: 12/08/2014, 16:20

... Standard Dose 400 IU Vitamin D3 daily High Dose 2000 IU Vitamin D3 daily Secondary Outcomes: Parent reported URTI symptoms Wheezing episodes among children with asthma Influenza, adenovirus and ... during pregnancy and childhood bone mass at age years: a longitudinal study Lancet 2006, 367:36–43 Markestad T, Aksnes L, Ulstein M, Aarskog D: 25-Hydroxyvitamin D and 1,25-dihydroxyvitamin D ... cross-sectional studies of American and Costa Rican children suggested that children with vitamin D levels below 75 nmol/L had increased airway resistance and increased use of inhaled and oral steroids relative

Ngày tải lên: 02/03/2020, 17:25

... rats, demonstrated that the addition of vitamin D improved calcification in dentin He showed that rats with a vitamin D deficiency had a wide predentin region bordering the hypocalcified dentin ... early childhood caries (ECC) and patients without dental decay Materials and Methods: Serum vitamin D, PTH, and calcium levels were obtained from 30 children without dental decay who acted as controls ... PTH, and calcium levels in children with and without caries Inclusion and Exclusion Criteria To be included or excluded in this study, the following conditioned needed to be met:  Children

Ngày tải lên: 22/10/2022, 21:16

... data, served on the adjudicating committee and approved the final manuscript as submitted AJ.: Conceived and designed the study, contributed to drafting the manuscript and approved the final ... Contributed to study design and interpretation of the data, served on the adjudicating committee and approved the final manuscript as submitted ES.: Contributed to data collection, to the study design ... consent Data regarding breastfeeding practices, vitamin D supplementation and birth charac-teristics were collected via a standardized questionnaire, and responses were provided online and in telephone

Ngày tải lên: 01/02/2020, 03:59

... acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid d Sum of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid and α-linolenic acid e Sum of arachidonic ... intake and dietary intake of vitamin B12, alcohol and dietary intake of fat other than eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid e Sum of arachidonic and linoleic acids ... in Sweden low-fat dairy products and marga-rines are fortified with vitamin D Otherwise the dietary intake of vitamin D would be lower Furthermore, men were not included in the study and there

Ngày tải lên: 11/08/2014, 16:22

... were sectioned and stained with hematoxylin and eosin One section per rat was randomly selected and 6 fields per section were pho-tographed at 50 × at random avoiding blood vessels and airways The ... and bronchial tissues that were isolated from VAS rats and VAD rats that were untreated or had received RA for 4 or 12 days Northern analyses were preformed and the den-Effects of vitamin A deficiency ... led to more pronounced airspace enlargement in VAD rats This was evidenced as a larger Lm and SD Lm in VAD rats, indicating that the alve-olar ducts and alveoli were more dilated with air and

Ngày tải lên: 12/08/2014, 18:21

... DAB diaminobenzidinetetrahydrochloride DAPI 4′,6-diamidino-2-phenylindole Trang 27DNA deoxyribonucleic acid dsRNA double-stranded ribonucleic acid EDGE endothelial differentiation gene E2F1 e2f ... description(Goetz, 2011) 1.2 Epidemiology of PD PD is the second most widespread neurodegenerative disorder after Alzheimer's disease Nonetheless, appraisals of occurrence and predominance differ ... induced mouse model of Parkinson’s disease  Experimental Biology 2012 Meeting in Boston, MA Dysregulated Sphk1, Sphk2 and their receptors in the brain of induced mouse model of Parkinson’s disease

Ngày tải lên: 09/09/2015, 08:12

... DOPAC and hydrogen peroxide from oxidative deamination of DA In so doing, these drugs would decrease the formation of oxyradicals from hydrogen peroxide generated by DA metabolism and could thus ... (ROS) (peroxide, superoxide and hydroxyl radicals) If not handled properly, the ROS generated could create a considerable damaging environment Further, DA could auto-oxidize to DA-quinone, a ... years old) and is usually associated with dystonia and diurnal fluctuations as well as early and severe L-DOPA induced dyskinesia and sleep benefit (Saito, et al., 2004) Following the discovery

Ngày tải lên: 14/09/2015, 12:20

... Recommendations on vitamin D supplementation and treatment of vitamin D deficiency Trang 8There has not been also a widespread concensus on vitamin Dsupplementation and treatment of vitamin D deficiency ... with both GDM and vitamin D deficiency isnecessary On the other hand, until now relationships betweenvitamin D and IR in GDM have not been studied in Vietnam For these reasons we conducted the research ... (Vitamin D3)and Ergocalciferol (Vitamin D2) Vitamin D is converted to25(OH)D in liver by the first hydroxylation and in kidneys by thesecond one to 1,25(OH)2D that is biologically active and

Ngày tải lên: 11/05/2016, 08:56

... irradiation[93,97,98], have found that vitamin D exhibits photoprotective effects Documented effects on skin cells include decreased DNA damage, reduced apoptosis, increased cell survival, and decreased erythema ... response[65,66] Vitamin D and cutaneous adaptive immunity Early studies of vitamin D and the immune system demon-strated VDR expression in both T and B cells (Fig 2) [67] Notably, VDR expression ... and epidermal barrier function, and whether oral vitamin D supplementation or topical treatment with vita-min D analogs is helpful in healing surgical wounds Vitamin D and skin diseases Based

Ngày tải lên: 14/01/2020, 18:33

... O, Andersson S (2017) Towards evidence-based vitamin D supplementation in infants: vitamin D intervention in infants (VIDI) - study design and methods of a randomised controlled double-blinded ... D intake 24 2.3 Vitamin D recommendations 25 2.4 Definitions for vitamin D deficiency and sufficiency 27 2.5 Dietary intake of vitamin D and vitamin D status 28 2.5.1 Maternal vitamin ... with and without GDM; 3) describe vitamin D intake from food and identify food sources of vitamin D in 1-year-old infants, and finally, 4) investigate whether maternal or infant vitamin D status

Ngày tải lên: 19/03/2020, 12:49

... impact of VD on pCR and survival in an expanded cohort Methods: Patients from Iowa and Montpellier registries who had serum VD level measured before or during NAC were included Vitamin D deficiency ... or date of death (OS) Results: The study included 327 women Vitamin D deficiency was associated with the odds of not attaining pCR (p = 0.04) Fifty-four patients relapsed and 52 patients died ... in-cluded 183 additional patients in this study The deci-sion for NAC was validated in multidisciplinary boards based on the local standard of care Patients received se-quential anthracycline and/or

Ngày tải lên: 03/07/2020, 01:26

... included patients newly diagnosed with CRC from 1999 to 2003 and aged 20–75 years at the time of diagnosis Controls were selected by random digit dialing and matched on age (±5 years) and sex ... blood samples and for permission to access their tumor specimens and medical records (for cases) A total of 656 cases and 696 controls completed detailed questionnaires and donated a blood sample ... Crude model adjusted for age and sex b Multivariable model additionally adjusted for family history of CRC, screening procedure, multivitamin use, folic acid intake, smoking history, and education

Ngày tải lên: 24/07/2020, 00:33

... 19 and 70 for calcium intake as 800 mg/day and for vitamin D intake as 400 IU/day [22] The IOM Recommended Dietary Allowance (RDA) for calcium is 1,000 mg/day and for vitamin D is 600 IU/ day ... vitamin D were slightly increased We tested inter-action between calcium and vitamin D intake and race/ ethnicity among AA and EA study participants, and the interaction between total vitamin D and ... calcium and vitamin D intake were not independently associated with PCa Be-cause calcium and vitamin D intake were highly correlated and showed opposing directions of association, we investi-gated

Ngày tải lên: 20/09/2020, 01:12

... responses and have been associated with lower BC risk Moderate physical activity post-diagnosis reduces BC recurrence and mortality, partly explained by reduced insulin and estrogen levels Vitamin D ... months Dietary and exercise counselling and vitamin D supplements will be given at each clinic visit when blood samples, anthropometric measures and 7-day food records will be collected Discussion: ... unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate

Ngày tải lên: 20/09/2020, 01:13

... obesity and cancer: (1) obesity and cancer; (2) obesity and vitamin D; and (3) vitamin D and cancer A systematic review was performed for (1) and (3), whereas a meta-analysis including random effects ... whether vitamin D plays an important role in the pathway between obesity and cancer (Figure 1): (1) obesity and cancer; (2) obesity and vitamin D; and (3) vitamin D and cancer, while addressing ... obesity and cancer in a crude model, and a model adjusted for vitamin D [13] To our knowledge, no mediation analyses have been published to date for this question, with the exception of one study

Ngày tải lên: 14/10/2020, 16:10

... termVitamin D and Fracture Healing: produced 130 citations (of which 43were relevant); Vitamin D and Bone Healing: produced 318 citedstudies; Vitamin D and Callus Formation: produced 51 cited studies.Compared ... allocated to vitamin D deficient diets and sham operated rates receivednormal diets At 12 wk, a fracture was induced in the tibia and fixed Trang 9with a nail Bone and callus formation were monitored ... diabetes and vitamin Ddeficiency on bone repair in female mice Although vitamin Ddeficiency aggravated the decrease in bone mineral densityaccording to the diabetic state of the mice, it did

Ngày tải lên: 17/10/2022, 23:56

... 25(OH)D concentra-tion or are at increased risk of developing vitamin D deficiency A cross-sectional population-based study in China, India, and Iran found that vitamin D deficiency was related to ... testing programs of the Vitamin D External Quality Assessment Scheme (DEQAS) The results indicated less than ± 2.0 standard deviation index (SDI), except the those induced by random error The traceability ... strongly related to a low vitamin D level because a higher BMI leads to lower vitamin D level [33] Vitamin D receptors are widely expressed in adipose and β-pancreatic cells, and both cell types

Ngày tải lên: 31/10/2022, 03:17

... consid-ered as first-line therapy to control serum PTH [1 On the other hand, the Kidney Disease: Improving Global Outcomes (KDIGO) Chronic Kidney Disease – Mineral and Bone Disorder (CKD-MBD) guidelines ... Summary Secondary hyperparathyroidism is a com-plex disorder requiring an individualized con-ducted to identify treatment combinations used in clinical practice in Austria and Switzerland and the potential ... vitamin D analogues and phosphate binders, were adapted to individual patient requirements and treatment dynamics were documented Overall, the mean intact parathyroid hormone (iPTH) increased

Ngày tải lên: 04/12/2022, 15:03

... have developed and applied the 2D depth-averaged models in variety of hydraulic engineering problems as follows: McGuirk and Rodi (1978) studied the side discharge into an open channel and its ... gratitude and sincere thanks to Professor Dr Takashi Hosoda who suggested me this research topic, and provided guidance, constant and kind advices, encouragement throughout the research, and above ... a depth-averaged model in Cartesian coordinates and introduced the curved river boundary to the model through steps Tingsanchali and Mahesawaran (1990) presented a mathematical depth-averaged

Ngày tải lên: 06/11/2012, 10:35