virus human immunodeficiency virus

... Acquired Immunodeficiency Syndrome ARV Antiretroviral DMO District Medical Officer DOT Directly Observed Therapy (Short course) HAART Highly Active Antiretroviral Therapy HIV Human Immunodeficiency Virus ... Trang 1PULMONARY TUBERCULOSIS AMONG HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PATIENTS IN THE ERA OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) ... of the TB infection In recent years TB has become prevalent among people living with human immunodeficiency virus (HIV) which poses a major public health problem especially in Sub-Saharan Africa

Ngày tải lên: 22/03/2014, 18:20

... †Equal contributors Abstract Background: The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS) The HIV-1 Vpu ... S, Strebel K: The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1Vpu that enhances particle release of heterologous retroviruses J Virol 1996, ... Trang 1Open AccessResearch Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein – a genetic, biochemical and biophysical analysis

Ngày tải lên: 18/06/2014, 18:20

... inhibition of Human Immunodeficiency Virus type 1 in an inhibition assay Virol J 2006, 3:99. 12. Habte HH, de Beer C, Lotz ZE, Tyler MG, Kahn D, Mall AS: Inhibi-tion of Human Immunodeficiency Virus ... infectivity by human salivas AIDS Res Hum Retroviruses 1990, 6:1425-1432. 25. Shugars DC, Alexander AL, Fu K, Freel SA: Endogenous salivary inhibitors of human immunodeficiency virus Arch Oral ... Trang 1Open AccessResearch The inhibition of the Human Immunodeficiency Virus type 1 activity by crude and purified human pregnancy plug mucus and mucins in an inhibition assay

Ngày tải lên: 20/06/2014, 01:20

... Trang 1Open AccessResearch article Nonopportunistic Neurologic Manifestations of the Human Immunodeficiency Virus: An Indian Study Alaka K Deshpande*1 and Mrinal M Patnaik2 Address: 1 Professor ... induced by the virus results in demyelinating diseases of the central-and peripheral nervous systems (CNS central-and PNS) As the HIV infection progresses, the direct toxic effects of the virus unfold, ... vasculitis The cere-brospinal fluid (CSF) was examined for antibodies to vari-cella-zoster virus and cytomegalovirus as well as venereal disease research laboratory slide test (VDRL) titers, as these

Ngày tải lên: 20/06/2014, 08:20

... precursors on human immunodeficiency virus replication Chem Biol Interact 1994, 91(2-3):217-224. 18. Ho WZ, Douglas SD: Glutathione and N-acetylcysteine sup-pression of human immunodeficiency virus ... Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo Miriam C Poirier*1, Ofelia A Olivero1, ... Levy EM, Mandel R, DiSciullo GJ: Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interac-tion Proc Natl Acad Sci

Ngày tải lên: 10/08/2014, 05:21

... simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins J Virol 2002, 76:7874-7882 37 Milovanceva-Popovska... Inhibition of human immunodeficiency ... Inhibition of human immunodeficiency virus type-1 by cdk inhibitors Irene Guendel 1,3† , Emmanuel T Agbottah 2† , Kylene Kehn-Hall 3 , Fatah Kashanchi 1,3,4* Abstract Current therapy for human immunodeficiency ... 91:3862-3866 5 Antoni BA, Stein SB, Rabson AB: Regulation of human immunodeficiency virus infection: implications for pathogenesis Adv Virus Res 1994, 43:53-145 24 25 26 27 Dingwall C, Ernberg

Ngày tải lên: 10/08/2014, 05:21

... autoprocessing Background Human immunodeficiency virus 1 (HIV-1) is the causa-tive pathogen of AIDS The HIV protease is a virus-encoded enzyme absolutely required for virus propaga-tion and infectivity ... full-length human immunodeficiency virus type 1 molecular clones expressing protease JVirol 1995, 69:6810-6818. 13 Pettit SC, Lindquist JN, Kaplan AH, Swanstrom R: Processing sites in the human immunodeficiency ... human immunodeficiency virus type 1 transframe protein p6* for spatiotemporal regulation of protease activation J Virol 2008, 82(9):4573-4584. 22 Tessmer U, Krausslich HG: Cleavage of human immunodeficiency

Ngày tải lên: 10/08/2014, 05:21

... replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 1995, 206:935-944. 3. Freed EO, Englund G, Martin MA: Role of the basic domain of human immunodeficiency virus ... the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag) J Virol 20 01, 75 :10 537 -10 542 Poon B, Chen IS: Human immunodeficiency virus type 1 (HIV -1) ... Forget J, Yao XJ, Bergeron D, Cohen EA: Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages. J Exp Med 1998, 187:1103-1111.

Ngày tải lên: 12/08/2014, 04:20

... antiret-roviral therapy AIDS Res Hum Retroviruses 2003, 19:1155-1161. 15. Dumitrescu O, Kalish ML, Kliks SC, Bandea CI, Levy JA: Character-ization of human immunodeficiency virus type 1 isolates from children ... sabinoec@gmail.com * Corresponding author Abstract Background: The genetic diversity of the human immunodeficiency virus type 1 (HIV-1) is critical to lay the groundwork for the design of successful ... 15:F41-47. V, Cavalcante S, Galvao-Castro B, Mullins JI, Mayer A: Identification of human immunodeficiency virus type 1 envelope genes recombinant between subtypes B and F in two epidemiolog-ically

Ngày tải lên: 12/08/2014, 04:21

... infection by a number of enveloped viruses of medical importance, including human immunodefi-ciency virus-1 (HIV), herpes simplex virus (HSV) and influenza A virus [12-15] These inhibitory activities ... different Abbreviations HIV: human immunodeficiency virus; EIAV: equine infec-tious anemia virus; IC50: inhibitory concentration 50 (concentration of compound that inhibits 50% of virus ... the lentivirus equine infectious anemia virus (EIAV) is not inhibited by H perforatum subfractions E4.7 or E4.8 Figure 8 The infectivity of the lentivirus equine infectious ane-mia virus (EIAV)

Ngày tải lên: 12/08/2014, 04:21

... Trang 2Page 2 of 10Background The human immunodeficiency virus type 1 (HIV-1) which has high genetic diversity is classified into groups M, N, and O The group M viruses that are responsible for ... CRF07_BC R5 virus with that of the subtype B' R5 and R5/X4 viruses Figure 7 Comparison of the replication kinetics of the CRF07_BC R5 virus with that of the subtype B' R5 and R5/X4 viruses The ... drug-resistant human immunodeficiency virus type 1 J Virol 2001, 75:3291-3300. 35 Cecilia D, KewalRamani VN, O'Leary J, Volsky B, Nyambi P, Burda S, et al.: Neutralization profiles of primary human

Ngày tải lên: 12/08/2014, 23:21

... chimpanzees to humans and is the major causative agent of human acquired immunodeficiency syndrome (AIDS) pandemic [1-3] Although HIV-1 infects human CD4+ cells, it does not infect most non-human primates ... monkey TRIM5-CypA (omTRIMCyp) restricts several retroviruses including HIV-1, simian immunodeficiency virus (SIV) and feline immunodeficiency virus (FIV) [11,12] Recently, we and others reported ... non-human primate animal models Page of 12 (page number not for citation purposes) Retrovirology 2009, 6:58 http://www.retrovirology.com/content/6/1/58 Background Human immunodeficiency virus

Ngày tải lên: 12/08/2014, 23:21

... in early infection are well-characterized for simian immunodeficiency viruses (SIV), but less so for chimeric simian-human immunodeficiency viruses (SHIV), although the latter have been widely ... comparative study of Asian macaques infected intravenously with simian immunodeficiency virus (SIV) or simian-human immun-odeficiency virus (SHIV) strains, SIVmac251 or SHIV89.6P, Reimann et al found ... AccessResearch Pathogenic infection of Macaca nemestrina with a CCR5-tropic subtype-C simian-human immunodeficiency virus On Ho1, Kay Larsen2, Patricia Polacino2, Yun Li1, David Anderson2, Ruijiang Song3,4,5,

Ngày tải lên: 12/08/2014, 23:21

... sequence between alpha-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) vif and CA alpha-helices ... of the virus Unexpectedly, HIV-1 with this mutation became resistant to CM TRIM5α-mediated restriction Background Human immunodeficiency virus type 1 (HIV-1) produc-tively infects only humans ... NL4-3 virus was not affected by human TRIM5α, while that of NL-G116E was slightly suppressed by human TRIM5α These results suggest that the viruses with G116E substitution were more sensitive to human

Ngày tải lên: 13/08/2014, 01:20

... A R C H Open AccessMutations in matrix and SP1 repair the packaging specificity of a Human Immunodeficiency Virus Type 1 mutant by reducing the association of Gag with spliced viral RNA Natalia ... competent HIV-1 molecular clone renders the virus non-infectious in human T cell lines [11,33-37] However, SL1 deletion mutants have been shown to replicate in human PBMCs, and a pri-mary HIV-1 isolate ... p24-normalized NL4-3, NLΔSL1 and viruses from the infected PM-1 cells on day 14 p.i (NLΔSL1-D14) and on day 22 p.i (NLΔSL1-D22) were used to infect fresh PM-1 cells, and virus production was monitored

Ngày tải lên: 13/08/2014, 01:20

... Trang 1R E S E A R C H Open AccessSelective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation ... Kraus1, Barbara Müller2* Abstract Background: Current antiretroviral therapy against human immunodeficiency virus (HIV-1) reduces viral load and thereby prevents viral spread, but it cannot eradicate ... combination treatment with three or more antiviral drugs, allows the efficient control of human immunodeficiency virus (HIV) replication Under opti-mal conditions, suppression of plasma viral load

Ngày tải lên: 13/08/2014, 01:20

... Trang 1R E S E A R C H Open AccessA Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication Brian M Friedrich1†, James L Murray2†, Guangyu Li1, Jinsong ... including components of the IGF-II pathway for reovirus and Rab9 for Marburg virus, validating the initial hypothesis [1-3] Moreover, we reasoned that viruses evolved from common ances-tral archetypes ... capability to facil-itate replication of viruses from other families and found that disruption of the Rab9 pathway also limited the replication of Ebola virus, measles virus, and HIV-1 [1] HIV-1 replication

Ngày tải lên: 13/08/2014, 01:20

... Broadhead R, Miotti PG, Sokoll LJ, et al: Human immunodeficiency virus load in breast milk, mastitis, and mother-to-child transmission of human immunodeficiency virus type 1 J Infect Dis 1999, 180:93-98. ... Vendrell3,4,5,6* Abstract Background: Transmission of human immunodeficiency virus type 1 (HIV-1) through breast-feeding may involve both cell-free and cell-associated virus This latter viral reservoir remains, ... the suppressive effect of ART The virus produced by the HIV-1 infected latent CD4+ T cells becomes detectable as cell-associated virus, but not as cell-free virus, because of the low lymphocyte

Ngày tải lên: 13/08/2014, 01:20

... neurodegeneration Background Human immunodeficiency virus type 1 (HIV-1) infec-tion is a global health problem for which the pathogenic mechanisms causing disease occurrence and the acquired immunodeficiency ... ** * F ** ** * ** B D Figure 3 Human astrocyte transfection with HIV-1 Vpr mutant viruses (A) Transduced astrocytes showed that pseudotyped virus (pv) the Vpr77Q virus-transduced astrocytes; while ... residue induced higher IFN-a, MX1 and BST-2 transcript levels in human glia relative to the 77Q-HAD encoding virus (p < 0.05) but both viruses exhibited similar levels of gene expression and replication

Ngày tải lên: 13/08/2014, 01:20

... 5C-AxxA virus (Figure 1C and 1D) This dose resulted in equivalent infectivity between ΔNef virus and the initial dose of the SF2 Nef virus (Student’s t test p = 0.7), or between 5C-AxxA virus and ... and the 5C-AxxA virus repli-cated to 2-fold lower peak values compared to the 5C and 5C-3 viruses No difference was observed between the 5C and 5C-3 viruses, or the 6I-1 and 6I viruses At this ... Trang 1R E S E A R C H Open AccessNef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated

Ngày tải lên: 13/08/2014, 01:21