vi— expression of mucin genes in gallstone disease

... down-regulation of this gene by AC2 would prevent degradation of proteins involved in turning off defense responses, thus preventing the host from initiating a response to infection Interestingly, WRKY33, ... The C-terminus contains a minimal transcription activation domain within an acidic region A region containing conserved cysteine and histidine residues forms a putative zinc finger domain, with ... investigate the host genes that respond to gemini-virus AC2 protein during an infection Some microarray profiling of genome-wide changes in the transcriptome in response to geminivirus infection has

Ngày tải lên: 27/05/2020, 00:22

... repressed in skin following cortisol-receptor monomers binding to glucocorticoid response elements in the presence of corticosteroid binding protein [63] Our observed increase in Krt14 expression ... Also worth noting was the finding that about one third of these genes participate in apoptosis Expression levels and statistical evaluation of genes in the Cancer Pathway platform are included as ... and involves an increase in the neuroendocrine secre-tion of corticotropin-releasing factor and, ultimately, enhanced release of the glucocorticoid hormone corti-sol Of our genes displaying upregulated

Ngày tải lên: 06/08/2020, 04:04

... odorant binding proteins of insects Acta Entomol Sin 45, 131–137 (2002) (in Chinese). 23 Grozinger, C M., Sharabash, N M., Whitfield, C W & Robinson, G E Pheromone-mediated gene expression in ... like expression of chemosensory genes in S exigua and effects of sex pheromones and plant volatiles on the expression levels of olfactory proteins, which therefore modify the olfactory profile of ... hours after initiation of darkness in the incubator indicating that these genes exhibit a circadian pattern Effects of sex pheromones and plant volatiles on OBP, PBP, and ABP expression in S exigua

Ngày tải lên: 19/03/2023, 15:21

... portal vein, leading to the stable formation of metastases within 4 weeks RNA sequencing performed on the Illumina platform was employed to evaluate the expression profiles of more than 14,000 genes, ... dysregulated genes Conclusion: Bioinformatics assists in elucidating the factors and processes involved in CRC liver metastasis Our results support the notion of an invasion-metastasis cascade involving ... gene expression results between the cell line and liver metastases This filtering step was done in order to identify genes representing differences in cell line ver-sus tumour, instead of general

Ngày tải lên: 06/08/2020, 07:07

... photomicrographs of Ep-ICD staining a Shows predominantly Ep-ICD Cyt staining in normal oral mucosa with some stromal staining; b Increased cytoplasmic and nuclear staining is observed in dysplasia; ... immunostaining; b Oral dysplasia showing intense EpEx Mem staining; c OSCC section illustrating reduced EpEx Mem in tumor cells; d OSCC section used as a negative control, showing no EpEx immunostaining ... upregulation of EpCAM expression as well asits increased proteolysis that would account for in-creased Ep-ICDNuc Interestingly, the increased regulated intramembranous proteolysis of EpCAM resulting in

Ngày tải lên: 20/09/2020, 14:10

... function of IL-18 in the autoimmune sialoadenitis of SS has not been investigated, aside from a recently reported study [3] in which the mRNA expression of several cytokines (including IL-18) in minor ... become uncoupled from or independent of the level of cellular infiltration In addition, the demonstra-tion of increased ductal expression of IL-18 in SS would be in keeping with other autoimmune ... Crohn's disease [13,28,29,39] make this cytokine a prime candidate also in the pathogenesis of SS Increased serum levels and salivary gland expression of IL-18 in patients with SS is in keeping with

Ngày tải lên: 09/08/2014, 01:23

... Figure 2 Increased expression of LOX and ED-A FN in dcSSc skin Increased expression of LOX and ED-A FN in dcSSc skin Cryosec-tions of (a,b) normal skin are compared with (c-f) dcSSc skin In normal ... four-fold eleva-tion of creatinine kinase accompanied by the clinical finding of proximal weakness defined muscular involvement, whilst renal involvement was determined by history of scleroderma renal ... Myofibroblasts are present only in fibrotic dcSSc skin The distribution of myofibroblasts was investigated using the 1A4 monoclonal antibody against α-SMA In normal skin, α -SMA immunostaining

Ngày tải lên: 09/08/2014, 07:20

... comparison of genes with similar basal expression levels, we used expression-profiling data to bin genes according to their basal expression levels We found that inducible genes in the lower basal expression ... induci-ble genes in T cells To facilitate comparison of genes with similar basal expression levels, genes were binned according to their basal expression levels determined from expression profiling ... clustering of all of the methylation marks and the genes in the Log2 3 to 6 basal expression bins to ask whether primary response genes in the lower basal expression bins may be enriched for genes

Ngày tải lên: 09/08/2014, 20:20

... aberrations in the often chaotic karyotypic profiles of solid tumors Massively parallel RNA-sequencing (RNA-seq) using next-generation sequencing instruments allows identifi-cation of gene fusions in individual ... reported to interact with Bcl-xL, and Ras in T-cells, resulting in the inhibition of apoptosis [29,30] IKZF3 is located at the ERBB2-amplicon [31] Interestingly, our preliminary analysis of clinical ... importance of the VAPB-IKZF3 fusion gene We present multiple lines of evidence suggesting the potential functional importance of the fusion genes, including the involvement of known oncogenic partner genes,

Ngày tải lên: 09/08/2014, 22:23

... MYB binding site involved in drought-inducibility MBSI x MYB binding site involved in flavonoid biosynthetic genes regulation MBSII x MYB binding site involved in flavonoid biosynthetic genes ... (1) involved in shoot-specific expression and light responsiveness AT- rich element x binding site of AT-rich DNA binding protein (ATBP-1) ATCT-motif x part of a conserved DNA module involved in ... that all genes encode for an aminotransferase class-V motif and alignment analysis showed the location of a cysteine in the active site and a histidine and alanine in the cofactor binding site

Ngày tải lên: 11/08/2014, 11:21

... analysis of 48 tissues and organs at various stages of growth and by continuous gene expression profiling of leaves at weekly intervals from transplanting until harvesting Our gene expression profiling ... overexpres-sion of AtHAP2 delays flowering via down-regulation of FT [34] In SD-flowering rice plants, the CCT-domain containing proteins Hd1 and Ghd7 regulate flowering by repressing expression of the ... time of induction of FT-like gene expression in leaves under the natural field conditions, and revealed interesting trends suggesting the potential role of similar or related signal-ing events in

Ngày tải lên: 11/08/2014, 11:21

... Figure 3 Expression profiles of Actinidia flowering genes in mature plant organs Real-time RT-PCR analysis of the Actinidia flowering genes in the root, stem internode, leaf, flower and fruit of two ... 3LV Figure 5 Expression profiles of Actinidia flowering genes in normal and aberrant flowers Real-time RT-PCR analysis of the Actinidia flowering genes in the leaf and floral organs of A deliciosa ... on the timing of floral commitment, ranging from the spring of the first grow-ing season [4,5,9] or late summer of the first growgrow-ing season [10], to the spring of the second growing season,

Ngày tải lên: 11/08/2014, 11:22

... Department of Applied Biology, PO Box 27, FIN-00014 University of Helsinki, Helsinki, Finland, 2 Finnish Graduate School in Plant Biology, PO Box 56, FIN-00014 University of Helsinki, Helsinki, Finland, ... School in Biosciences, PO Box 56, FIN-00014 University of Helsinki, Helsinki, Finland, 4 Horticultural Sciences Department, University of Florida, Gainesville, FL, USA and 5 Institute of Biotechnology, ... Biotechnology, PO Box 56, FIN-00014 University of Helsinki, Helsinki, Finland Email: Katriina Mouhu - katriina.mouhu@helsinki.fi; Timo Hytönen* - timo.hytonen@helsinki.fi; Kevin Folta - kfolta@ifas.ufl.edu;

Ngày tải lên: 12/08/2014, 03:21

... Panax ginseng for all shared protein-coding genes Figure 4 Pairwise d N /d S of Nicotiana and Ipomoea vs Panax ginseng for all shared protein-coding genes Genes are ranked left to right by increasing ... retains the open reading frame, matK, con-tained within the intron of that tRNA A deletion within the trnV -CAU intron also reported in C reflexa [21], and similar to that seen in Orobanche minor, ... Analyses demonstrate photosynthetic genes are under the highest constraint of any genes within the plastid genomes of Cuscuta, indicating a function involving RuBisCo and electron transport through

Ngày tải lên: 12/08/2014, 05:20

... cultured with 2 d of TGFa and 4 d of KGF Similar findings were observed in ATII cells cultured in KGF (K) alone, in 2 d of K and 2 d of KD (data not shown) or in 2 d of KIA and 4 d of KIAD (Additional ... dysregulation of the Th1/Th2 cytokine is related to the pathogenesis of several adult lung diseases and alterations of surfactant proteins have been reported in variety of lung diseases, the effect of IL-13 ... its site of synth-esis to the lamellar bodies [53,54] Cathepsin H is one of the cysteine proteases involved in the processing of proSP-B and proSP-C The first N-terminal processing step of proSP-C

Ngày tải lên: 12/08/2014, 11:23

... sig-nificant increase in the numbers of WBC at calving This was mainly due to an increase in the numbers of circulating neutrophils, and to a less extent, an increase in monocytes At calv-ing, the ... collected in the morning, using Vacutainer® tubes (Becton Dickinson Vacutainer Systems, Meylan, France), one month before estimated calving, at calving (within 24 hours after calv-ing) and one ... dry matter intake (DMI) of 10 dairy cows one month before ex-pected calving, at calving, and one month after calv-ing, expressed in kilograms of dry matter and in per-centage (%) of the total

Ngày tải lên: 12/08/2014, 15:20

... supported by the increase in BAL ET-1 in lung allografts [72,73] The in vivo gene transfer of ET-1 to the airway epithelium using the hemagglutinating virus of Japan in rats recently resulted in pathologic ... monocro-taline treated rats [101,102] The increase in ET-1 in both of these forms of pulmonary hypertension may be contributing to increases in vascular tone as well as in vas-cular remodeling [103–106,114] ... inflamma-tory cells in the lung Since ET-1 may act as an immune modulator, an increase in ET-1 may contribute to lung injury by inducing expression of cytokines including tumor necrosis factor and

Ngày tải lên: 12/08/2014, 18:20

... Glutamine synthase immunostaining Glutamine synthase immunostaining A: Normal expression of GS around the central vein (non -nodular tissue) B: Extended staining around hepatic veins ... taking advantage of glutamine synthase (GS) staining; this stain- ing technique recognises hepatic veins surrounded by GS- positive hepatocytes or the distal part of zone 3 if the cen- tral vein ... and α SMA staining GS and α SMA staining A closer view (see Fig 8 box in the middle): upper micrograph (A) has GS staining, and lower... pathogenesis of FNH from a single case It

Ngày tải lên: 13/08/2014, 13:20

... role of the N-terminal part of the kinase, containing a PAS domain, was established in signal transduction between the RH and the kinase [6,7] Addition of H2 to HupUV before or during the incubation ... single point mutation in the helix–turn–helix DNA binding motif of PpsR, rendering it inactive [26] Comparison of HupSL regulations and the functional roles of HupTUV in other T roseopersicina ... transcript level of the hupTUV genes is below the detection limit or is missing in T roseopersicina Mutagenesis and homologous expression of the hupT and hupTUV genes In- frame deletion mutagenesis was...

Ngày tải lên: 16/03/2014, 23:20

... points following infection with varying MOIs Analysis of recombinant protein production in these samples will indicate how much virus is needed to obtain maximal yield after a given time of infection ... with the intended use (in vitro, in vivo, structural biology) The design of a suitable expression vector for an expression system of choice, also including a potential "tagging" of the protein to ... as neomycin or hygromycin, positive transfectants can be selected in media containing the corresponding antibiotic Induction of gene amplification using glutamine synthetase22 or dihydrofolate...

Ngày tải lên: 11/04/2014, 09:41