this is the stu that stars are made of

... consists of three essays that address the issue of the business value of Information Technology (IT) in the context of the Internet economy The first essay studies the productivity of IT in the ... provided by other companies The cost of sales of most physical dot coms consists of the cost of merchandise sold and inbound/outbound shipping There are other important distinctions between these two ... for most of the companies in the dataset, this study first uses the number of employees as a proxy for the labor input The total labor cost can be thought of as a product of the number of employees...

Ngày tải lên: 18/02/2014, 11:20

... including the subject matter, price, and conditions of the agreement ● Acceptance2: Acceptance is the offeree's unequivocal agreement to the terms of the offer It must mirror the terms of the offer ... intellectual property protection This analysis will examine the main aspects of the dispute and its implications At the heart of the dispute is Apple's claim that Samsung has infringed its intellectual ... remedies and protections in case of disputes or non-compliance b Structure ● Offer1: An offer is a proposal made by one party (the offer) to another party (the offeree) that indicates a willingness...

Ngày tải lên: 06/02/2025, 16:21

... perihelion is called the major axis of the ellipse and half that distance, the semi-major axis, gives the size of the ellipse It is approximately the average distance between the planet and the Sun, ... was that the distance of the Sun from Earth is much greater than the distance of the Moon so that the angle θ is only a little less than 90◦ This meant that, since small differences from 90◦ made ... Aristarchus tried to measure the angle θ shown in the figure This angle would not give the actual distances of the Sun and the Moon from Earth but it would give the ratio of the distances of the...

Ngày tải lên: 06/07/2014, 15:31

... years of experience in the area of HIV-1 replication fitness PLS has published key papers in this area that are cited in this manuscript HBC is a post doctoral associate and is working in the area ... selection of L74V is mainly associated with the use of didanosine This study showed that the selection of L74V and L74I is controlled by two independent pathways and it is speculated that the resistance ... DNA synthesis at low dNTP concentrations [36] RT codons 65 and 74 are parts of the highly flexible b3-b4 linkage group in the finger subdomain of the 66 kDa subunit of HIV RT [37] Analysis of HIV-1...

Ngày tải lên: 11/08/2014, 21:21

... inseparable In fact, there's this stupid joke going around, that we share the men, which of course, is absurd And to tell you the truth, despite the fact that we have been seeing each other for so many ... as racist as us Christians That, I couldn't stomach Mum's veto, that is You see, Daniel's, that' s Dani‟s name, Daniel's father is dead and his mother is a tough old bitch who controls the purse ... mother and I got to know him He is the designer of the clothes she produces The modéliste They say that domineering women tend to produce weak and sometimes abnormal sons Well, Moni's mother is...

Ngày tải lên: 06/11/2012, 17:33

... Y310F tau, this band was not apparent on western blots of lysates of Y394F tau (Fig 2A) The absence of this larger species could indicate that phosphorylation of tau by Fyn is reduced and therefore, ... The SH3 domain of Fyn binds to proline-rich motifs within the sequence PXXP in interacting proteins Seven such motifs are present in the proline-rich domain of the longest isoform of tau in the ... Fyn are important for the cellular distribution of these proteins For example, we have shown that the trafficking of tau to DRMs [9] and plasma membranes [5] is Fyn-dependent As we found that the...

Ngày tải lên: 14/02/2014, 14:20

... but not the PI3-Kc isoform contributes to platelet procoagulant activity following P2Y12 stimulation Discussion The results of the present study highlight the importance of the ‘weak’ agonist, ADP, ... platelets This suggests that it is not Ca2+ reuptake itself that is controlled by PI3-K, but a different process that is still dependent on normal Ca2+-ATPase function A remarkable finding is that the ... considerable amount of the PIP3 formed in platelets [21], this may suggest that the PIP3 produced by this isoform leads to plasma membrane binding and, hence, activation of PH domain-containing...

Ngày tải lên: 18/02/2014, 16:20

... region of Rac1b (dotted green line on the right), where the 19 amino acid insertion of Rac1b is found, is disordered in the crystal The mostly disordered structures of the switch II region are compatible ... The positions of the Lys147 residues are almost identical Lys147 of Rac1 is yellow, and the equivalent residue of Rac1b is shown in orange on top There is only a minor change in orientation of ... addition Therefore, the reason why Lys147 rather than Lys5 is the main acceptor site for ubiquitin in Rac1 remains to be elucidated Of note, however, is that recent studies on the role of the Rab-like...

Ngày tải lên: 18/02/2014, 16:20

... GC supports the hypothesis that ERK1/2 is an important signalization pathway in the regulation of steroidogenesis by LN in GC Conclusion The results of this study emphasize the role of cytoskeleton ... (percentage of labeled cells) and the pyknotic index (percentage of pyknotic cells) after 48 h of culture This has been shown to allow the be the optimal culture time for the study of the effects of various ... c and d) Overall analysis of results of this experiment showed the existence of significant correlations between the percentage of round cells and the proliferation rate of GC from small follicles...

Ngày tải lên: 05/03/2014, 17:20

... young The date the first egg was laid was used as the measure of the beginning of the breeding season for a female The ‘end of the breeding season’ was estimated as the date of failure or fledging of ... 1995) The trend for lower survival of yearling females in pairs compared to groups is inconsistent with this hypothesis, but it is possible that lower effort emphasizes a pre-existing effect of ... 4b) It is possible that there are differences in the quality of breeding locations unrelated to the ‘territory quality’ index To assess this possibility, pairwise comparisons were used of seasonal...

Ngày tải lên: 14/03/2014, 16:20

... Adherents of this argument often posit that the revolutionary origins of the regime predispose it toward the acquisition of nuclear weapons and other weapons of mass destruction Along these lines, ... and coherence Their comments significantly strengthened the substance of the report and its recommendations Of course, the content of this report is the sole responsibility of the authors Abbreviations ... of the hijab.42 It is important to note that bureaucratic politics may also be driving this juxtaposition of internal dissent and external interference The MOIS has been at the forefront of this...

Ngày tải lên: 15/03/2014, 21:20

... by Nd1, as is the case with other RNase A-like enzymes The orientation of the His97 ring in the deposited structure (PDB code 2i5s) was determined, on the basis of the B-factors of the imidazole ... on the constellation of all atoms within the unit cell In other words, the crystal structure is encoded in the diffracted X-rays – the shape and symmetry of the cell define the directions of the ... approximation of the true structure, depending on the accuracy of the calculated phases, that is, on how good the model is from which the phases were computed Another type of electron-density map, the...

Ngày tải lên: 16/03/2014, 06:20

... V8d ẳ V8r ẳ Together, the graphs depicted in Fig 6BF show that the inhibition in the rate of synthesis of ATP from ADP is accompanied by an increase in the rate of synthesis of Ino, without any ... these results would indicate that H2O2 diminishes the rate of synthesis of ATP, probably through inhibition of glycolysis It is worth noting that H2O2 has no appreciable effect on the level of ... Effect of H2O2 on glycolysis From the above, it seemed obvious to verify in our experimental conditions the eect of H2O2 on either the rate of glucose consumption or on the rate of synthesis of ethanol...

Ngày tải lên: 17/03/2014, 10:20

... structures and other oligomers is growing, given that the toxicity of these species appears to surpass that of mature fibrils [76] It is possible that the toxicity of aggregates is simply correlated ... indicating that the growth of type Bunagitated depends on the remaining nonfibrillated glucagon concentration rather than on the amount of type A fibrils formed before them [63] This is inconsistent ... In the case of glucagon, clues to the mechanism of this acceleration can be observed in the morphology of the resulting fibrils, with agitation generally producing type Bagitated fibrils, which are...

Ngày tải lên: 23/03/2014, 03:20

... yield is the ratio of the total activity of OGDHC in the eluate to the total activity of the OGDHC applied to the column ND, not determined Dissociation of E1o from OGDHC Dissociation of E3 from ... rates This is in accordance with published data on the rate-limiting role of the E1o component in Reaction (1) catalyzed by the complex [34] It is known that the binding of E3 to OGDHC is mediated ... substitution of this interaction for that with synaptic membrane interferes with the integrity of the complex This may explain the observed difference in the stability of brain and heart OGDHC over the...

Ngày tải lên: 23/03/2014, 06:20