... stimuli 114 3.2.8 MOAP-1 is a key short-lived protein required for Bax function in mitochondria 117 3.2.9 Conclusions 120 3.2.10 Acknowledgement 121 DISCUSSION 122 4.1 MOAP-1 IS A MITOCHONDRIAL ... of MOAP-1 which is required for its degradation 109 3.2.6 The center domain of MOAP-1 is required and sufficient for mediating its degradation by UPS 111 3.2.7 Elevating MOAP-1 protein ... Bcl-2 as an oncogene 14 1.3.2 The Bcl-2 family 16 1.3.2.1 Bcl-2 homolog (BH) domains 16 1.3.2.2 Three classes of the Bcl-2 family 18 1.3.2.3 Models for the functional interplay among
Ngày tải lên: 14/09/2015, 12:54
... over the world but have not yet been applied in Vietnam This study aimed to identify the present of the molecular markers linked to CMD resistant gene (SSRY106, NS158, NS169, NS198 and RME-1) in ... ISSN: 1859 - 1558 Giấy phép xuất bản Số: 351/GP - BTTTT Bộ Thông tin và Truyền thông cấp ngày 11 tháng 8 năm 2020 Trang 7Tạp chí Khoa học và Công nghệ Nông nghiệp Việt Nam - Số 02(123)/2021 Identification ... NGHIỆP VIỆT NAM Journal of Vietnam Agricultural Science and Technology 60 68 74 79 85 90 97 103 110 115 12 Trần Hoàng Em, Lê Vĩnh Thúc, Trần Chí Nhân, Lý Ngọc Thanh Xuân, Trần Ngọc Hữu, Phạm Duy
Ngày tải lên: 15/03/2024, 10:42
Báo cáo khoa học: A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbb and removes Rev-erbb-induced inhibition of apoCIII transcription potx
... Fax: +86 21 65642505 Tel: +86 21 65642505 E-mail: honglu0211@yahoo.com (Received 27 June 2007, revised 15 August 2007, accepted 22 August 2007) doi:10.1111/j.1742-4658.2007.06062.x The orphan ... FEBS 5379 ZNHIT-1 as a cofactor of Rev-erbb 10 11 12 13 14 15 16 J Wang et al orphan steroid receptor Rev-erbb ⁄ Rev-erb beta is dependent on the signature motif and helix in the E region: functional ... chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4 Proc Natl Acad Sci USA 101, 13 513–13 518 ´ 36 Li B, Pattenden
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Purification and structural analysis of the novel glycoprotein allergen Cyn d 24, a pathogenesis-related protein PR-1, from Bermuda grass pollen pot
... Taiwan 112 Fax: +886 22875 1562 Tel: +886 22871 2121 ext 3379 E-mail: snsu@vghtpe.gov.tw (Received 9 June 2005, revised 27 Septem-ber 2005, accepted 3 OctoSeptem-ber 2005) doi:10.1111/j.1742-4658.2005.05000.x ... Lett 402, 167–172 17 Focke M, Hemmer W, Hayek B, Gotz M & Jarisch R (1998) Identification of allergens in oilseed rape (Bras-sica napus) pollen Int Arch Allergy Immunol 117, 105–112 18 Astruias ... isoforms⁄ degraded protein products and around 65 of these are IgE-binding proteins [19] Only a few of these proteins have been purified and characterized so far In the present study, we isolated a 21
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Conformational and functional analysis of the lipid binding protein Ag-NPA-1 from the parasitic nematode Ascaridia galli potx
... like the Trp residue of the 0.00 0.05 0.10 0.15 1.0 1.1 1.2 1.3 [acrylamide] M F 0 /F Fig. 3. Quenching of Trp fluorescence of Ag-NPA-1 by acrylamide. A value of 1.3 M )1 was calculated for the ... nematode protein Ag-NPA-1 FEBS Journal 272 (2005) 180–189 ª 2004 FEBS 185 average distance between these chromophores. The dis- tance approaches 1.41 nm which suggests that Trp17 of Ag-NPA-1, like the ... Sofia 1756, Bulgaria Fax: +359 28621059 Tel: +359 28626036/210 E-mail: r.boteva@ncrrp.org (Received 27 July 2004, revised 17 September 2004, accepted 20 September 2004) doi:10.1111/j.1432-1033.2004.04398.x Ag-NPA-1
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway doc
... 131 651 1085 Tel: +44 131 651 1025 E-mail: craig.stevens@ed.ac.uk (Received 28 July 2010, revised 7 October 2010, accepted 11 November 2010) doi:10.1111/j.1742-4658.2010.07959.x We previously identified ... FLAG–TSC2 FLAG–TSC1 – + B A IB: FLAG IB: TSC1 FLAG–TSC2 FLAG–TSC2 (1–1516) – + TSC2 (1–1516) TSC2 TSC2 (1–1516) TSC2 IB: Actin IB: FLAG IB: TSC1 IP: TSC1 Lysate IB: FLAG IB: TSC1 IB: FLAG IB: DAPK ... (Fig 3A) To further demonstrate that TSC2 (1–1516) interacts normally A TSC1 binding TSC2 TSC2 (1–1516) LZ CC N1693K FLAG–TSC2 Actin FLAG–TSC2 (1–1516) Actin Chx (h) FLAG–TSC2 (N1693K) Actin B
Ngày tải lên: 28/03/2014, 23:20
Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot
... lanes 9, 10, 11 and 12), albeit with differ-ent affinities SAFB1 binds tightly to SRPK1a and almost as tightly to SRPK1 (compare lanes 2 and 1) and the same holds true for the GST–SAFB1CDRE protein ... 11 12 Eluate Beads Fig 5 Binding of the GST–SAFB1/2 proteins on immobilized FLAG–SRPK1/1a proteins FLAG–SRPK1 and FLAG–SRPK1a were immunoprecipitated on beads by from HeLa cell extracts and the ... 5545 Tel: +30 241 068 5581 E-mail: egeorgat@med.uth.gr Website: http://www.med.uth.gr (Received 24 January 2009, accepted 16 July 2009) doi:10.1111/j.1742-4658.2009.07217.x SR protein kinases
Ngày tải lên: 30/03/2014, 01:20
Báo cáo sinh học: " Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein – a genetic, biochemical and biophysical analysis" ppt
... recruits other proteins such as Skp1, Cul-1 and the Cdc34 E2 ubiquitin ligase [11] This results in ubiquitination of CD4, its dislocation from the ER and degradation by the proteosome [12,13] The stable ... and Wilkins; 2001:1971-2041 2. Strebel K, Klimkait T, Martin MA: A novel gene of HIV-1, vpu, and its 16-kilodalton product Science 1988, 241:1221-1223. 3. Bour S, Strebel K: The human immunodeficiency ... modulate these pathways and control processes important for viral replication Thus, protein-protein interactions are an important aspect of the functioning of these proteins The Vpu protein of HIV-1
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: " Imperfect DNA mirror repeats in the gag gene of HIV-1 (HXB2) identify key functional domains and coincide with protein structural elements in each of the mature proteins" doc
... 22 21 21 21 21 21 20 19 19 19 19 19 19 19 18 18 18 18 18 18 18 mIMR DNA begin 1158 1314 1087 1349 74 1302 17 562 322 478 734 930 1022 1404 356 838 1146 772 1189 1253 268 361 1238 1274 990 63 159 ... AA 1261 803 108 1279 300 200 97 1408 212 226 274 259 1118 644 1100 515 1131 409 918 988 1051 673 1066 612 953 1297 33 733 1130 21 155 170 128 346 63 184 112 156 337 38 382 585 667 696 967 1059 ... 1215 767 73 1245 267 168 68 1379 184 198 246 232 1091 618 1074 490 1108 385 894 964 1027 650 1043 590 931 1275 12 712 1109 135 150 109 327 45 166 95 139 320 22 367 565 647 676 947 1039 832 910
Ngày tải lên: 18/06/2014, 18:20
Báo cáo y học: " Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNF-induced MEK/ERK signalling" ppsx
... 0.99 1.55 1.26 Cacna2d3 [GenBank:NM_175595] Calcium channel, voltage-dependent, 2/3 subunit 0.82 1.56 0.99 Cd68 (predicted) [GenBank:NM_001031638] CD68 antigen 1.01 1.80 1.14 Cgref1, Cgr11 [GenBank:NM_139087] ... [GenBank:NM_139087] Cell growth regulator with EF hand domain 1 1.01 0.61 0.83 Cyp4b1 [GenBank:NM_016999] Cytochrome P450, family 4, subfamily b, polypeptide 1 1.71 1.72 1.83 Gm1960, Cinc2, ... [GenBank:NM_017178] Bone morphogenetic protein 2 0.89 1.61 1.53 Gdf10 [GenBank:NM_024375] Growth differentiation factor 10 colony-stimulating factor 1 0.86 2.37 2.17 Spp1, OSP [GenBank:NM_012881] Secreted
Ngày tải lên: 09/08/2014, 01:22
báo cáo khoa học: " Identification and characterization of the Nonrace specific Disease Resistance 1 (NDR1) orthologous protein in coffee" doc
... [AGI:At3g20600]; NHL1 [AGI:At3g11660]; NHL2 [AGI:At3g11650]; NHL5 [AGI:At1g61760]; NHL6, [AGI: At1g65690]; NHL11 [AGI:At2g35970]; NHL12 [AGI:At2g35960; NHL16 [AGI:At3g20610]; NHL18 [AGI:At3g52470]; NHL21 [AGI:At4g05220]; ... [AGI:At5g05657] The accession number of the Nicotiana tabacum Hin1 coding sequence is GenBank: AB091429.1. Trang 4CaNDR1a/b NtHin1 Class 1 Class 3 AtNDR1 CaNDR1a/b NtHin1 Class 1 Class 3 (a) (b) AtNDR1 1 ... CaNDR1a 111 HDKKARR KEL V QT Y GVPWEAAY RAV SNGS T VT FRV G T TRVRYKILFW Y TKR H - LKVGA CaNDR1b 111 HDKKARR KEL V QT Y GVPWEAAY RAV SNGS T VT FRV G T TRVRYKILFW Y TKR H - LKVGA AtNDR1 174 D
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1" docx
... of P9-1 do not interact with P6 We also investigated P9-1 regions crucial for P6-P9-1 interaction A dozen P9-1 BD-fused deletions that express fusions BD-P9-11-197, BD-P9-11-207, BD-P9-1 1-248 ... protein, respec-tively [8,11,12] The protein encoded by S3 is assumed to have some guanylyltransferase activity [13] Proteins translated from S8 and S10 are the components of the major capsid and ... Despite the lack of detectable protein sequence homology with animal reovirus proteins, P6 possesses A SD/AHWL AD-P6 1-449 341-792 271-703 B 274-703 395-703 395-659 1-197 1-207 1-248 76-347
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: "Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines" ppsx
... in RPMI 1640, resu spended to a hematocrit of 1% in 1 ml of complete DMEM with the chemokines RANTES, MIP-1a, SDF-1 or AOP-RANTES at concen- trations of 0, 0.1, 1, 10, and 100 nM for 1 h at 37°C ... Louisiana 70112 USA Full list of author information is available at the end of the article Bolton and Garry Virology Journal 2011, 8:45 http://www.virologyj.com/content/8/1/45 © 2011 Bolton and ... manuscript. Both authors read and approved the final manuscript. C16 K19 R20 K21 K22 R40 R41 C29 C36 C45 Y94 N95 K96 R103 L168 I175 V3-like loop Domain 1 Domain 2 Domain 3 Figure 5 T hree dimensional
Ngày tải lên: 11/08/2014, 21:22
báo cáo khoa học: " The Arabidopsis EAR-motif-containing protein RAP2.1 functions as an active transcriptional repressor to keep stress responses under tight control" docx
... water loss [15] Another example of EAR-repressors are the key members of the C2H2 zinc-finger family of proteins, such as ZAT7 [23], ZAT10 [16] and ZAT12 [17,18] These proteins suppress the repressors ... repressor To examine whether RAP2.1 could interact specifically with the DRE motif, we expressed the N-terminal 120 aa of the RAP2.1 protein (containing the AP2 Figure 1 RAP2.1 binds to DRE and acts as ... RAP2.1, rap2.1-1 (SALK_092889) and rap2.1-2 (SALK_097874), in which the T-DNAs were inserted into the promoter and 5’-UTR regions of the RAP2.1 gene, respectively (Figure 3A) Both rap2.1-1 and
Ngày tải lên: 12/08/2014, 03:21
Báo cáo y học: "The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis" pot
... G→T GCCTG(G/T)GCGAG G1 31 C 5 /11 8 (4.2%) ZFP36 *12 PCD (ex.2) 211 2 C→T GCCTT(C/T)TCTGC F232→F 4/97 (4 .1% ) ZFP36 *13 PCD (ex.2) 218 4 C→A AGGGC)CA_ACTCC A256→A 10 /94 (11 %) ZFP36 *15 PCD (ex.2) 3059 A→C ... [23] The arrow indicates the migration position of the ARE probe (lanes 1 6) and the deadenylated product of probe ARE-A50 (lanes 9, 11 , 12 , 14 , 16 and 17 ) (b) The extracts used in lanes 7 13 of ... zinc finger mutant (C124R), CMV.cMG1.tag (cMG1), CMV.mTis11D.tag (mTis11D), 0 .1 µg of human poly(A) exonuclease (hPARN) expression plasmid CMV.hPARN.flag (hPARN), or plasmid DNA alone (BS+) The...
Ngày tải lên: 09/08/2014, 01:24
Tài liệu Báo cáo khoa học: Crystal structure of the BcZBP, a zinc-binding protein from Bacillus cereus doc
... replaced by the acetate moiety The protein coordinates zinc with the Nd atom of His12, one of the Od atoms of Asp15 and the Ne atom of His 113 His 113 protrudes from helix a4 whereas His12 and Asp15 both ... with the same residues coordinating a zinc ion These residues plus an additional conserved motif (Fig 7B) in the immediate neighborhood of the active site (His 110 , Pro 111 , Asp 112 , His 113 in the ... with the protein encoded by bc1534 [4,5] Furthermore, bc1534 also has a homologue in the B cereus genome, the bc34 61 gene, with 25% identity, at the amino acid level The protein encoded by bc1534...
Ngày tải lên: 19/02/2014, 00:20
Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt
... 64, 314 – 319 Zinc- binding protein in the sea urchin 20 Brooks JM & Wessel GM (2002) The major yolk protein in sea urchins is a transferrin-like, iron binding protein Dev Biol 245, 1 12 21 Yokota ... part of the zinc in the immature gonads is bound to MYP The elution patterns of zinc were similar in the ovary and testis, but the zinc peak in the immature ovary was larger than that in the immature ... 43 .1 ± 1. 7% of the MYP was CFMYP at stage and 18 .3 ± 2.6% at stage In the testes, the proportions of CFMYP were 17 .7 ± 5.3% at stage and 6.9 ± 3.5% at stage The higher the proportion of CFMYP, the...
Ngày tải lên: 16/03/2014, 05:20
Báo cáo khoa học: The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-DisplacementProtein (CUX1) repressor ppt
... Journal 277 (2 010 ) 42 41 4253 ª 2 010 The Authors Journal compilation ª 2 010 FEBS 42 51 ´ I Frechette et al CUX1 represses PLZF transcriptional activity 10 11 12 13 14 15 16 17 18 19 20 gene expression ... p200Cux1 (e.g p 110 Cux1) as well as alternative splicing (e.g p75Cux1) [12 ] Many in vitro gene targets of CUX1 are implicated in the control of the cell cycle [10 ,13 ,14 ] Genetic deletion of Cux1 in ... validated for the absence of CUX1 interaction did not compete, as illustrated for sites 8, 10 , 12 , 13 , 14 and 15 in Fig 2C The addition of affinity-purified polyclonal CUX1 antibodies to the binding...
Ngày tải lên: 29/03/2014, 21:20
Thụ thể hormon adrenalin, Protein G và các chất truyền tin thứ hai
... ớt hn so vi nóo (12 , 22) (Logothesis et al., 19 88) Cỏc dimer 12 v 13 cú kh nng kớch thớch hot tớnh ca adenylate cyclase kiu II mnh gp 10 ln so vi 11 (Iniguez Lluhi et al., 19 92) Cỏc tiu n v ... C (Blacklund et al., 19 90; Fung et al., 19 90; Maltese v Robinshaw, 19 90; Mumby et al., 19 90a; Yamane et al., 19 90; Sanfod et al., 19 91) Nhúm farnesyl 15 C trờn (Lai et al., 19 90) ớt k nc hn nhúm ... et al., 19 87) Mt vi khỏng th iu khin chng li cỏc peptit vựng u C cng khụng ghộp cp vi th th t protein G (Simon et al., 19 89; Gutowski et al., 19 91) Peptit photorhodopsin i din cho 11 gc cui...
Ngày tải lên: 23/10/2013, 18:20
Thử nghiệm sử dụng protein bột nhân hạt cao su thay thế một phần protein bột cá trong khẩu phần ăn của cá rô phi ( OROCHROMIS NILOTICUS ) giai đoạn thương phẩm nuôi trong giai
... Cao 02 4 ,10 1, 60 5,99 1, 60 8 ,10 1, 60 24 4 ,14 1, 62 6,30 1, 62 8,03 1, 62 4-6 4,34 1, 67 6,26 1, 67 8 ,14 1, 67 6-8 4,48 1, 68 6,26 1, 68 8 ,15 1, 68 - 10 4,49 1, 65 6,28 1, 65 8 ,17 1, 65 (Trong ... a a a 2,58 0 ,14 2,58 0 ,16 2,57 0 ,15 2,58a 0 ,15 10 ,34a 0, 81 10,27a 0,80 10 ,24a 0,82 10 ,11 a 0,95 18 ,46a 2,89 18 ,22a 2,22 18 ,00a 2 ,12 17 ,93a 2,23 25,06a 4,49 24,79a 4, 31 24,70a 4,38 ... trờng nớc .12 1. 3 Chất lợng nớc yếu tố môi trờng ảnh hởng tới cá Rô phi 12 1. 3 .1 Nhiệt độ 12 1. 3.2 Oxy hoà tan (DO) 13 1. 3.3 Độ pH 13 1. 3.4 Hyđrosulfide...
Ngày tải lên: 18/12/2013, 20:56