... water from other essential needs (e. g., agriculture) The developed world has not been immune to these pressures The removal of regulatory and legislative restrictions in countries like the United ... While there were no illnesses reported because much of the mistreated water was diverted into rivers, the mayor of the city acknowledged they were lucky as no oversight system was in place to ... treatment plants United Water was expected to help the city eliminate discharge of untreated sewage, but an independent audit showed the exact opposite happened because of the company’s desire...
Ngày tải lên: 13/02/2014, 06:20
... interested institutions and persons are needed that are aware of the local economy and have an inherent interest in the development of the region Germany has a unique system of decentralized ... cumulative process the banking system may reinforce a core-periphery structure In the case of Germany the savings banks are of special interest because of their ubiquitous existence and their publicly ... promotes an interest in the economic development of the region and could theoretically thereby contribute to a balanced regional development However, neo-classical economists assume that free market...
Ngày tải lên: 16/02/2014, 10:20
Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx
... More likely, the difference in reported structures is associated with the collection and interpretation of the NMR data Their spectra were recorded in CDCl3 and COSY spectra lacked fine detail HSQC ... the double bond between C22 and C23 of these molecules The biological significance of P450scc-catalysed metabolism of vitamin D and its precursors cannot be underestimated because P450scc-generated ... holding vitamin D3 in solution, we also examined the metabolism of vitamin D3 incorporated into the membrane of phospholipid vesicles, more closely resembling the normal membrane environment of P450scc...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx
... failed because the UDP-glucuronidase activity was inhibited by the detergents or because the detergents were unable to solubilize the enzyme properly Ongoing experiments with overexpressed UGT1A6 ... To test whether the enzymes catalysing the formation of glucuronate and glucuronate 1-phosphate were present in the lumen of the ER (or had their catalytic site oriented towards the lumen of this ... absence (black bars) or presence (grey bars) of mM metyrapone (A) The effect of the heated high-speed supernatant was further analysed in the absence (B) or presence (C) of 10 mM ATP-Mg and in the...
Ngày tải lên: 19/02/2014, 07:20
The analysis of vitamin c
... 3‐2 Although we could use the first permanent appearance of the yellow color of dilute iodine to mark the end point of the titration, better results are obtained when starch is added as an indicator ... cover with a piece of aluminum foil Rinse the buret with a few milliliters of the I2 solution three times Drain and then fill the buret with the I2 solution After taking an initial reading of the ... iodine solution Note the change of the I2 color as you swirl the flask gently and continuously during the titration Continue the addition of the iodine, using progressively smaller volume increments,...
Ngày tải lên: 03/03/2014, 11:49
Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc
... Escherichia coli The recombinant protein contained an engineered enterokinase cleavage site in the junction between the GST tag and the Rv1771 sequence Upon h of induction of the pDEST15_Rv1771 E ... PAGE revealed the presence of one protein band of about 70 kDa (Fig 1, lane 2) The identity of the protein was confirmed by enterokinase treatment After digestion of the affinity-purified GSTtagged ... in other bacterial genomes, we used the rat l-gulono-1,4-lactone oxidase as a query sequence in blast searches of the protein database These searches retrieved, for a limited number of bacterial...
Ngày tải lên: 07/03/2014, 12:20
báo cáo hóa học:" Comparison of the effects of vitamin D products in a psoriasis plaque test and a murine psoriasis xenograft model" docx
... However, these studies compared the biomarker profiles before and after treatment with the calcipotriol ointment and they did not assess the effects of the vehicle on the biomarker responses ... two weeks All the transplantation procedures were performed under semi-sterile conditions The animals were stored in special-pathogenfree (SPF) environment during entire experiment The experiments ... three weeks, using an Eppendorf® combitip and they were rubbed into the lesions using a gloved finger The test sites were then covered with an unocclusive gaze and the system was secured on the...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Using animal models to determine the significance of complement activation in Alzheimer''''s disease" pptx
... significance of ADrelated complement activation because of the presence of NFTs as well as plaques Other animal species Scattered reports of AD-type pathology in other species have also appeared Adding ... different steps in the complement cascade All of these regulatory proteins are produced in the human brain, but less is known about their CNS synthesis in other species [31] The status of some of ... in experimental models of AD has been limited to mice and rats The extent of complement activation and its relationship to the development of AD-type neuropathology have generally not been determined...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo khoa học: "The significance of the Van Nuys prognostic index in the management of ductal carcinoma in situ" pps
... to influence the likelihood of recurrence Of these tumour size greater than 15 mm, intermediate or high nuclear grade, presence of comedo necrosis and intermediate or high VNPI scores were found ... 61) the recurrence rate and hence the chance of developing invasive breast cancer is minimal (0% over years, P = 0.002) These patients we feel should not receive RT For those with intermediate ... http://www.wjso.com/content/6/1/61 Figure The influence of the VNPI on disease free survival The influence of the VNPI on disease free survival be treated by re-excision plus or minus RT with an expected 100% cause specific...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo y học: "urgical correction of unsuccessful derotational humeral osteotomy in obstetric brachial plexus palsy: Evidence of the significance of scapular deformity in the pathophysiology of the medial rotation contracture" ppt
... line and a perpendicular line traversing the humeral head at its greatest diameter The distance of the scapular line to the anterior portion of the head and the greatest diameter of the humeral ... Additional measurements were made of the angle of the humerus to the trunk during the hand-tomouth movement (trumpeter sign) and the angle of forearm supination as a more sensitive determination of functional ... was performed The same surgeon performed all surgical procedures (RKN) Results The preoperative and postoperative Mallet scores for these patients are presented in Table with representative photographs...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity" ppt
... Figure In contrast to the potent antitumor activity of the formulation injected directly into the tumor site, there was no evidence of effect on the contralateral tumor site Experiment These experiments ... lymphocytes have no detectable insulin receptors, once they have received antigenic challenge, they acquire approximately 6,000 per cell [22-26] Since acquisition of these receptors is an early event ... switched from the adaptive mode of response to the amplification of natural immune mechanisms." "The increased serum level of cytokines and the array of neuroendocrine changes lead to fever, catabolism...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: "A systematic review of the role of vitamin insufficiencies and supplementation in COPD" docx
... b-carotene, and vitamin supplements Further articles were identified from the reference lists of the included articles In order to be as accurate as possible we included in the present review only ... advantages and disadvantages Serum levels of vitamins The assessment of serum levels of vitamins can have the advantage of being more objective than patient’s Page of reported intake However, serum ... level assessment of vitamins has the disadvantage that they represent the more recent intake, and for some vitamins such as vitamin C, the levels in peripheral blood are not representative of...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer" ppsx
... combination of these [84-87] Potential bacterial pathogens are detected in about 50% of exacerbations A therapeutic consequence would be the up-regulation of the innate immune defense system Wang ... by the relatively low number of subjects Furthermore, the time period of 12 weeks was probably too short to show any effect Taken together, there is growing evidence for a protective role of ... on the quality of the teeth 1925 Studies on experimental rickets XXI An experimental demonstration of the existence of a vitamin which promotes calcium deposition 1922 The effect of additions of...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo khoa học: "The significance of different formulations of aerosolized colistin" ppt
... declare that they have no competing interests References 418 Mubareka S, Rubinestein E: Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative ... colistin, the risk of perpetuating these organisms and other emerging resistant pathogens will only increase, particularly in high-risk areas such as intensive care units Competing interests The author(s) ... Critical Care August 2005 Vol No Michalopoulos et al spp and other non-fermenting Gram-negative rods Nevertheless, the broader microbiological picture must also be considered where nosocomial infection...
Ngày tải lên: 12/08/2014, 22:21
Báo cáo y học: "Pathways to child and adolescent psychiatric clinics: a multilevel study of the significance of ethnicity and neighbourhood social characteristics on source of referral" pptx
... prerequisite for a referral to mental health care, and parental awareness of the existence of a problem has been identified as the key initial step in help-seeking [14] However, referrals to mental health ... mental health care than others [21], and that ethnic differences in referral pathways emerge as a consequence of this There are also results indicating the presence of ethnic differences in the ... judge their behaviour as deviant and consequently refer them to the mental healthcare [21] Socio-cultural differences may also manifest themselves in ethnic differences in families’ perceptions of...
Ngày tải lên: 13/08/2014, 18:21
Báo cáo sinh học: " The significance of controlled conditions in lentiviral vector titration and in the use of multiplicity of infection (MOI) for predicting gene transfer events" pot
... titre The sensitivity of cell lines to lentivectors was generally MOI dependent We further examined whether the sensitivity of these cell lines to lentivectors-mediated EGFP gene transfer was dependent ... contribute to the time dependence of the transduction efficiency observed in the present experiments A further contribution to the volume effect may be increased cellular phospholipid uptake from the ... cells), the use of MOI was thus affected Considerable differences existed in the sensitivity of lentiviral vector-mediated gene transfer in several conventional cell lines The sensitivity of lentivector-mediated...
Ngày tải lên: 14/08/2014, 19:22
THE SIGNIFICANCE OF SARGASSUM ON SINGAPORES REEFS
... downloaded sequences and the sample sequences as detailed in the Materials and Methods The best representative GenBank sequences for each clade in the dendrogram were selected and the phylogenetic analysis ... half decades Sargassum was persistent on the reefs (the basal portions are perennial), with higher densities on the reef flat than the reef crest The densities on the reef crest ranged between 15 ... analysis repeated with these representatives and the sample sequences (Fig 2.3) The tree showed six distinct clusters, corresponding to the five "species" morphotypes described earlier Three clusters...
Ngày tải lên: 09/09/2015, 11:25
The significance of subjective cognitive decline in primary care and memory clinic patients
... the preclinical stages of AD These criteria are detailed in section 2.3 after the temporal development of AD has been outlined Despite major advances in the understanding of the development of ... criteria and assessment methods Heterogeneous terminology in the literature A review of the relevant literature reveals a variety of terms to describe subjectively experienced cognitive worsening ... cost-effective intervention strategies need to be developed in order to relieve health care systems and improve the life of patients and their caregivers (Wimo et al 2013) 2.2 Temporal development:...
Ngày tải lên: 26/11/2015, 10:00
The Significance Of The Language For Accounting Theory And Methodology
... interpretation to support the main aim of the research, the significance of language 1.4 The Structure of the Thesis The structure of the thesis or the sequence of arguments is illustrated to explain ... scenarios could be assumed: either adjust the level of applied language to the level of the system, to acquire a better understanding of the system, or degrade the complexity level of the system ... number of elements, the functions of each element, the ways each element relates with the other elements, etc are not always simple enough to be drawn in a fixed chart so as to be easily explained...
Ngày tải lên: 10/12/2016, 15:29
Content marketing and the significance of corporate branding
... qualitative interviews and of the selection of the companies interviewed Later presented are the results of the interviews implemented on the decision makers of companies operating in B2B markets in ... chapters the results of the interviews are presented The decision makers´ perspectives on the significance of a strong brand, and the goals, expected outcomes, perceived benefits and results of their ... and the names of their companies are not revealed Therefore the companies are called A, B, C, D and E, and the reference at the end of every quotation indicates which company has made the comment...
Ngày tải lên: 19/12/2016, 12:18