the search for candidate genes involved in pathogenesis

... and genes involved in Neuron Projection (51 genes) and Axon Projection (31 of the same genes) We further probed the high-confidence target genes for relevance to ASD by comparing them with the ... across the de-veloping and adult human brain [14, 15] We also used the brain data to note whether miRNAs that were highly-expressed in brain were also detected in the saliva regardless of whether they ... total cluster mappings The top subnodes in the anno-tation clusters were then examined, revealing more than 2-fold enrichment of genes involved in Transcriptional Activation (present in five subnodes

Ngày tải lên: 27/02/2020, 12:40

... cells, and therefore, an aerial epidermis transcriptome might be more efficient in identifying the candidate genes involved in the synthesis of wax and cutin [27] Here, we quantified the levels ... expressed in LW and I indicates not expressed in HW * indicates the genes annotated in Fatty acid elongation pathway, wax, and cutin and suberin biosynthesis pathway in Fig 4b, c and d ** indicates the ... (controlling for principal component), K (controlling for kinship), PCA + K (controlling for both principal component and kinship), Q + K (controlling for both population structure and kinship),

Ngày tải lên: 28/06/2021, 20:42

... Vietnamese and their civilization reminds me of the old institutions of the Mine Dvnasty. With such a positive opinion of the Vietnamese envoys, Yi Yu-won became interested in the history of the Đinh, ... becoming lost and adrift in the southwest sea during the winter of 1801 ended up making a round trip to the Ryukyu Islands, Ningbo (seaport in the northeast of Zhejiang p r o v i n c e ) , the ... ere taking place in V ie tn a m , the in creasin g political c risis in the Korean government, described above, had been u n fo ld in g since the late nineteenth century In this context, the situation

Ngày tải lên: 16/12/2017, 01:35

... Passie voor Vis BV Nijvis Holding BV Lake Veerse Country The Netherlands The Netherlands The Netherlands The Netherlands The Netherlands The Netherlands The Netherlands The Netherlands Origin Wild (seawater) ... The importance of re­annotation of genes for gene expression in silver eel samples. Differences in gene expression values for the four silver eel samples, highlighting the genes involved in the melanocortin system that were re­annotated in this study. The ... involved in the processing of fish Pomc [40]. PC1 mediates the initial processing of Pomc into ACTH, β­LPH and N­terminal peptide in the corticotropes of the pituitary rostral pars distalis, while in the melanotropes located in the pituitary pars intermedia, PC2

Ngày tải lên: 26/09/2019, 16:15

... protein kinase kinase kinase 2; G: Mitogen-activated protein kinase kinase kinase 2; H: Auxin influx carrier; I: Auxin response factor 4; J: G-type lectin S-receptor-like serine/threonine-protein ... family proteins, the group of protein phosphate 2C, the members of serine/threonine –protein kinase SnRK2, and ABA responsive element binding proteins [35, 36] In A.sinensis calli during salinity stress, ... (compound 36) during the early inducing period (Fig 3b) These two compounds are also the main 2-(2-phenylethyl)chromones in agarwood and kept increasing in the wood tissues of A sinensis with the time

Ngày tải lên: 22/05/2020, 04:28

... all the NAC domain-encoding genes as PpNACxx, where Pp is the species initials (Pinus pinaster) and xx is the number given in the ordered identification in the SustainpineDB The identified NAC genes ... The subdomain distribution on the N-terminal region of on different NAC proteins is showed in the Additional file Most of the maritime pine NAC proteins contain subdomains A to E in the DNAbinding ... subdomains (A-E) The function of the NAC domain has been associated with nuclear localization, DNA binding and the formation of homo or heterodimers with other NAC domaincontaining proteins [19] In

Ngày tải lên: 26/05/2020, 20:08

... observed in kernel as compared to the other tissues Pericarp, flower and leaf contained mainly ring-intact triterpenoids The initial genes such as AiGDS, AiFDS and AiSQS involved in the isoprenoids ... L E Open AccessTriterpenoid profiling and functional characterization of the initial genes involved in isoprenoid biosynthesis in neem (Azadirachta indica) Avinash Pandreka1,2†, Devdutta S Dandekar1†, ... skeletons (Fig 1) Although the biosynthetic pathway leading to the formation of triterpe-noids (Fig 2a) in Neem plant has been predicted [1, 7] genes involved in triterpenoid biosynthesis have not been

Ngày tải lên: 26/05/2020, 22:00

... during the formation of the secondary xylem (xylogenesis) are involved in determining the physical and chemical properties of wood [2,7] Despite the progress that has been made in defining the molecular ... CAD catalyzes the reduction of cinnamaldehydes to cinnamyl alcohols, which is the last step in the biosynthesis of the monolignols, thus playing a pivotal role in determining the lignin monomer ... supplementation, results in the downregulation of genes from the phenylpropanoid pathway, with the exception of genes involved in the final steps of sinapilic acid synthesis (ATOMT1 and CAD) This

Ngày tải lên: 27/05/2020, 00:21

... modifications in the zinc-finger motif, indicating that these genes might be functional Moreover, another highly conserved domain, the zinc cluster, was identified upstream of the WRKY domain in IId ... available in the current literature The x denotes significant differences (p < 0.05) The genes indicated in bold were used in further analyses The genes were ordered according to the clustering analysis ... WRKY-encoding genes in transcriptional reprogramming during P pachyrhizi infection in soybean plants [17-22] To determine which soybean WRKY genes are involved in plant defense against P pachyrhizi infection,

Ngày tải lên: 27/05/2020, 01:13

... synthesis was performed in a thermal cycler in the following order: 27 °C for 10 min, 38 °C for 15 min, 44 °C for 40 min, 72 °C for 15 min All the primers which were used to detect viral genes ... role of HPV in lung cancer pathogenesis in two ways: i) the impact of HPV on the expression of genes involved in EMT, ii) the impact of HPV in the development of chronic inflammation and microenvironment ... indicate if changes were made The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the

Ngày tải lên: 05/11/2020, 01:45

... aberrations indicated either the response to the chemo-therapy or the RFS, and others indicated both These findings also indicated that genetic aberrations that cor-relate with difficulty in achieving ... thought to be involved in the resistance to trastuzumab-containing chemotherapy in HER2+/HR+ breast cancer [8] However, there have been few studies aiming to resolve the mechanism of chemo-therapy ... staining using an avidin-biotin complex for the validation of genomic alterations identi-fied by the SNP array in breast cancers Neoadjuvant and adjuvant chemotherapy and adjuvant hormone therapy

Ngày tải lên: 05/11/2020, 06:28

... approach in searching for candidate genes involved in specific biological processes of interest General trends in the expression of common groups of genes in response to a specific stimulus in diverse ... biological processes driven by these genes Starting from the notion that genes coding for proteins involved in the same biological processes are regulated in coordinated manner, and that expression ... finding that indirectly validates our approach (Table 2) Given the pre-eminent importance of the vascular component in ALI pathogenesis, our primary trait in selecting candidate genes was their...

Ngày tải lên: 09/08/2014, 20:20

... when interpreting the outcome results For example, salt stress treatment results in a rapid decline in photosynthesis within minutes [37] Therefore, genes that are regulated by photosynthetic ... stresses in sunflower Among them, many genes potentially encoding components involved in photosynthesis, such as photosystem proteins, chlorophyllbinding proteins, Rubisco and light harvesting proteins ... but they are not regulated by salt stress per se In another study the expression of 150 genes in response to wounding and insect feeding was carried out [58], finding that some of the responding...

Ngày tải lên: 12/08/2014, 05:20

... regulated in wild-type cells For example, the genes involved in amino acid metabolism were not regulated by amino acid starvation in GCN2) ⁄ ) cells, whereas enrichment for the genes involved in cholesterol ... that the GCN2 pathway is directly involved in the regulation of amino acid and protein metabolism, as many of the genes involved in these processes are not regulated in GCN2) ⁄ ) cells These ... nature of the stimulus, RNA binding factors and the sequence of the target mRNA [35] Another amino acid sensing mechanism involves mTORC1 Therefore, it is tempting to speculate that the mTORC1...

Ngày tải lên: 07/03/2014, 03:20

... enthusiasm for Mr Bush’s style by complaining that there wasn’t enough use of instinctive judgment in forming foreign policy The regress from the seventeenth-century “Age of Reason” to the instinctive ... the growth engine of the U.S economy, indicated his uncertainty by referring to the tentativeness of our projections.” He then asked, “What if, for example, the forces driving the surge in the ... if the benevolence of the gods driving the surge in the flood waters begins to dissipate or reverse in ways we not now foresee?” There is nothing new in the way that irreducible uncertainty induces...

Ngày tải lên: 11/06/2014, 10:32

... network of the JA biosynthesis pathway The genes in the yellow boxes in the network correspond to the yellow-colored components of the JA biosynthesis pathway indicated in Figure The genes in white ... genes for ETR1 and MPK6 (represented by the pink and green dot almost in the middle of the network), are in between the super cluster with the genes encoding proteins involved in SA signaling (red ... network of the ET biosynthesis and signaling pathways In panel A, the genes in the blue boxes in the network correspond to the blue-colored components of the ET biosynthesis pathway indicated in Figure...

Ngày tải lên: 11/08/2014, 11:20

... containing genes of interest involved in conifer defence First, many conifer defence genes exist as closely related members of large families For example, genes encoding the oleoresin producing ... presumably inserted into the BAC during proliferation The left and right arms of the BAC vector (pIndigoBAC-5) were used to orient the remaining contigs, resulting in the final builds of PGB02 ... binding sites (37 for 3CAR; 19 for CYP720B4), implicated in light responsiveness in several other plant species Interestingly, the promoter sequence including the transcribed 5'-UTR of the 3CAR gene...

Ngày tải lên: 12/08/2014, 03:21

... green indicating the region involved in the stem-loop-stem structure, and pink indicating the domain that binds Sm proteins The corresponding interaction region in U6atac snRNA is also marked in ... for all other core protein genes, indicating that all 24 genes are active There are 63 Arabidopsis proteins corresponding to the 35 snRNP-specific proteins used as queries in our genome mapping ... SMN protein complex In human, the SMN protein (survival of motor neurons) can interact with a series of proteins including Gemin2, Gemin3 (a helicase), Gemin4, Gemin5 and Gemin6 to form an SMN...

Ngày tải lên: 14/08/2014, 14:21

... interest in Arabidopsis Changes in the scientific culture of the 1980s which paralleled these technological advances also increased interest in the plant (Fink, 1998) and set the stage for a boom in ... of the Trichome Spacing Pattern The mechanism responsible for generating the spacing pattern on the surface of first true leaves has been intensely investigated during the past decade (Larkin ... preferentially with the bHLH dimer, preventing expression of genes involved in trichome development TTG would act in the cytoplasm most probably aiding in the association of the bHLH dimer 13 enters the nucleus...

Ngày tải lên: 14/11/2014, 11:55

... interest in Arabidopsis Changes in the scientific culture of the 1980s which paralleled these technological advances also increased interest in the plant (Fink, 1998) and set the stage for a boom in ... of the Trichome Spacing Pattern The mechanism responsible for generating the spacing pattern on the surface of first true leaves has been intensely investigated during the past decade (Larkin ... preferentially with the bHLH dimer, preventing expression of genes involved in trichome development TTG would act in the cytoplasm most probably aiding in the association of the bHLH dimer 13 enters the nucleus...

Ngày tải lên: 14/11/2014, 12:16