... ester-induced disruption of the CD4–Lck complex occurs within a detergent-resistant microdomain of the plasma membrane Involvement of the translocation of activated protein kinase C isoforms ... and then with 125 l M GM3 for 5 min. Trang 4HC11 cells treated with [D]-PDMP and EGF(Fig 3D), indicating that EGF is not determinant in defining the retention of ErbB2 into the lipid rafts The ... (heterodimerization, signa-ling and metabolic fate) [10] We therefore analyzed the role of gangliosides in the association of ErbB2 with lipid rafts in mammary epi-thelial HC11 cells The key role played by...
Ngày tải lên: 23/03/2014, 10:21
... The aim of the existing research was to determine the influence of SCMP on OP with the mediating effect of innovation The findings have revealed that a SPS had insignificant influence on OP The ... organization in long-range (Maalouf, 2018) One of the prior studies reveals that organizations maintain their strong positions in the existing market due to permanent investment in innovation and innovation ... performance 1 Introduction Supply chain management practices (SCMP) was gaining popularity in early 1990s when whole the world was facing with massive competition in the world market in delivering goods...
Ngày tải lên: 27/05/2020, 03:22
The role of communication in breast cancer screening: A qualitative study with Australian experts
... time there has been growing interest in encouraging and supporting members of the public to be more informed about health matters, including screening, and more engaged in decisions about their ... screening They endorsed the existing strategy whereby the screening provider is the main source of guidance They also approved of current participation targets for screening units, suggesting they ... Conception of values underpinning the “Be screened ” approach Conception of values underpinning the “Be screened and here ’s why” approach Conception of values underpinning the “Screening is available,...
Ngày tải lên: 22/09/2020, 23:55
Circuit theory of finance and the role of incentives in financial sector reform
... placing money with investment financial institutions in the capital market, and hold the remaining share in interest bearing, short-term bank deposits (eq 7) The share of savings going to the ... Creating a strongerinvestor base amounts to strengthening the circuit by completing the financial market structure ofthe economy, thus eliminating discontinuities in the transmission of information ... CTF: the role of incentives13Depending on the economy’s institutional setting (including the role of the state, restraints on market competition, and restrictions on capital movements), the circuit...
Ngày tải lên: 24/10/2012, 09:33
Tài liệu THE ROLE OF UNIVERSITIES IN REGIONAL INNOVATION SYSTEMS - A NORDIC PERSPECTIVE pdf
... potential of new knowledge might be biggest in thelatter case The growth of the minicomputer industry in the Boston region inthe 1960s and the internet industry in Silicon Valley in the19990s ... define the system of innovation a priori Our point of departure isthe universities in the selected regions The issue is to explore the role of theuniversities in the economic transformation of the ... the definition of a system of innovation is thatthe problem of delimiting the system increases In Lundvall (1992) this prob-lem is addresses by saying that determining which institutions to include...
Ngày tải lên: 16/01/2014, 16:33
Tài liệu Improving health, connecting people: the role of ICTs in the health sector of developing countries ppt
... to examine individuals and groups within the key institutions in the health system as target beneficiaries for ICTs, and in doing so to examine the issue of their capacity and needs, and the potential ... around the world, as indicated in Table 3 Inequitable access also exists within societies Within developing countries segments of the population have been by-passed by the products of the information ... there is growing evidence of the ability of ICTs to: • provide new and more efficient methods of production • bring previously unattainable markets within the reach of the poor • improve the...
Ngày tải lên: 14/02/2014, 09:20
Tài liệu Research " THE ROLE OF EDUCATION IN ECONOMIC TRANSITION AND POLITICAL TRANSFORMATION IN POST-COMMUNIST COUNTRIES " ppt
... p 33) Another striking feature of the transition was that the fall in the official GDP coincided with the rise of an informal economy If the latter were included into the accounting of GDP that ... persisted there during the rest of the nineties, with the highest in the CIS rates of 6-7 percent Finally, relatively gradualist reforms along with massive inflow of foreign capital into the oil ... investment in education in these post-communist countries The first chapter analyzes the determinants of economic growth in these countries and focuses on the role of investment in education in the...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx
... which appear to be involved in the final resorption of the parental macronucleus during PND in T thermophila, and suggested the involvement of mitochondria in this process [19] In mammalian apop-tosis, ... All of the following experiments were car-ried out in the following conditions: 200 lL reaction containing 20 lg protein, incubated for 120 min at 30C The putative DNase had an optimum pH of ... would be insufficient for ladder formation in the present study However, our findings imply that the nuclease activity is involved in the process of DNA laddering (as is the case with EndoG) rather...
Ngày tải lên: 20/02/2014, 03:20
Tài liệu Báo cáo khoa học: NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131 pptx
... pointing in opposite directions The stabilization of the folded conformation can be explained bythe stacking of the Val3 side chain with the Pro7 ring and bya hydrophobic cluster formed bythe ... parameter is involved in their binding to the receptor As a corollaryof this argument, it has often been assumed that the conformation of the hormone in the complex corresponds to the predominant conforma-tion ... Hz) of the backbone couplings for Tyr4 and His6 are possibly the result of twisting or bending in the middle of the amino-acid sequence of the hormone [49] Structure calculations and analysis The...
Ngày tải lên: 20/02/2014, 23:20
Tài liệu Investigating the Role of Poultry in Livelihoods and the Impact of Avian Flu on Livelihoods Outcomes in Africa docx
... Aning, Turkson, and Asuming-Brempong 2008; Obi, Oparinde, and Maina 2008; Omiti and Okuthe 2008) Therefore, information regarding the role of poultry in the livelihoods of small-scale producing ... solely the poultry income, thereby providing a more accurate measure of the impact of the disease If one looked only at the impact of HPAI on the income from poultry without accounting for its role ... detail the role of poultry (both as a source of income and as an asset) in the entirety of the households’ income and asset portfolios Regarding the sources of data used in this study, for the...
Ngày tải lên: 21/02/2014, 01:20
Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
... modification of interactions with other proteins (enhancing the interac-tion with reacinterac-tion partners, discouraging unfavourable contacts) or with the membrane (avoiding sticking to it while enabling ... direction The inverse is the case for the attraction in the case of Anabaena Also, if the structure of the final complex in which electron transfer takes place remained unaltered with increasing ionic ... desolvated The importance of desolvation of the encounter complex in protein–protein association has been Trang 8stressed by others [42,43] The increase in both DHand DSwith increasing ionic...
Ngày tải lên: 21/02/2014, 01:21
báo cáo hóa học:" The ability of cancer-specific and generic preference-based instruments to discriminate across clinical and self-reported measures of cancer severities" doc
... presented as the proportion of the sample within each group The QOL scores of the investigated instruments are reported as Tukey’s values Before testing the ability of the instruments to discriminate ... 0.55) of QLQ-C30 The functional well-being of the FACT-G was highly correlated with the role functioning (r = 0.61) and the physical functioning (r = 0.58) of the QLQ-C30 The social domains of QLQ-C30 ... preference-based instruments, which incorporate broad domains covering all aspects of QOL Furthermore, most items in the investigated instruments, except those in the HUI2/3, incorporate aspects of coping...
Ngày tải lên: 20/06/2014, 15:20
Tài liệu Misconceptions about the Causes of Cancer pptx
... and opinions expressed by them are, therefore, their own and not necessarily reflect the opinions of the members or the trustees of The Fraser Institute Printed in Canada National Library of Canada ... According to the Pew Research Center for the People and the Press, each of the top 10 stories of public interest in the United States during 1999 were about bad news With the exception of the outcome ... work, its interest lies in finding the reasons Where competitive markets have been replaced by government control, the interest of the Institute lies in documenting objectively the nature of the improvement...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu The Burden of Cancer in American Adults ppt
... that of women 65 and older; however, the incidence of breast cancer in middle-aged women is almost as great as the incidence of lung and colorectal cancer in older women The Burden of Cancer in ... diagnosed within the past year Of the estimated 6.5 million women with cancer history, 15% were diagnosed within the past year Among middle-aged adults, those aged 40 through 64, 4% of men and 6% of ... respectively The Burden of Cancer in American Adults Mortality and survival Cancer mortality is a function of both the incidence and survivability of cancer Cancer is the second leading cause of death in...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu The role of cancer registries docx
... should be taken as their incidence date Information on the most valid basis of diagnosis is of great interest in assessing the quality of the registration data The minimum requirement of a cancer registry ... way of obtaining information on the burden and patterns of cancer in developing countries, as well as providing a focus for research into etiology and prevention The discussion in the rest of ... registries play an important role in epidemiology by quantifying the incidence and prevalence of the disease in the community and as a source of ascertainment of cancer cases in intervention, cohort...
Ngày tải lên: 15/02/2014, 04:20
Tài liệu Misconceptions About Environmental Pollution, Pesticides and the Causes of Cancer doc
... smokers Men with inadequate diets or who smoke may damage the DNA of their sperm as well as the DNA in the rest of their cells When the level of dietary Vitamin C is insufficient to keep seminal fluid ... from the major task of improving public health through increasing scientific understanding about how to prevent cancer (e.g., the role of diet), increasing public understanding of how lifestyle influences ... “Predictions of ecological doom, including recent ones have such a terrible track record that people should take them with pinches of salt instead of lapping them up with relish For reasons of their...
Ngày tải lên: 18/02/2014, 04:20
The Burden of Cancer in Asia doc
... than 4% of the world’s new cases of each of these cancers occur in the United States In of these Asian countries, lung cancer has the highest incidence rate (age-standardized) of all cancers in males, ... countries is highest in Taiwan, Singapore, and Philippines in comparison, incidence in the United States is much higher than in any of the Asian countries In China, the female all-cancer incidence rate ... almost half (47%) of all new cases of uterine cervix cancer, with India alone diagnosing 27% of these cases 25 The burden of cancer in Asia Percent of new worldwide cases of cancer in females by...
Ngày tải lên: 06/03/2014, 01:20
Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc
... recombinant protein contained an engineered enterokinase cleavage site in the junction between the GST tag and the Rv1771 sequence Upon h of induction of the pDEST15_Rv1771 E coli strain with isopropyl-b-dthiogalactopyranoside ... participates in the covalent binding of the FAD molecule [22] (Fig 2) Analysis of the denatured Rv1771 protein by SDS ⁄ PAGE according to the method of Nishikimi et al [23] did not reveal the presence of ... protein band, thus pointing to the absence of a covalently bound flavin moiety in the recombinant product Moreover, as in the case of the plant l-galactono-1,4-lactone dehydrogenase [12], the native...
Ngày tải lên: 07/03/2014, 12:20
THE FACTORS AFFECTING THE USE OF ELDERLY CARE AND THE NEED FOR RESOURCES BY 2030 IN FINLAND pot
... elderly in general have been declining in the late 90’s As the DiffAGE85+ parameter is indefinite in sign results not indicate a pressure to increase the supply of care in homes for the elderly The ... Simulations The growth in operating costs is of the same order of magnitude as the rise in the number of care personnel The € 508 million operating cost of the domicile elderly care in the year 1999 is ... from the analysis of the Figure 2, that a lot of interesting features are hidden in probability structures of the estimated models However, the main goal of the models presented here is in their...
Ngày tải lên: 14/03/2014, 17:20