... by the overexpression of Bcl-2/Bcl-xL or by the complete ablation of Bax and Bak [22] The induction of apoptosis mediated by the extrinsic pathway is initiated by binding of death ligands to their ... induce apoptosis of macrophages Figure 4 Loss of Bid does not alter the cytokine and chemokine milieu of the joint Loss of Bid does not alter the cytokine and chemokine milieu of the joint (a) Pro-inflammatory ... including Trang 4invasion of leukocytes, proliferation of synoviocytes resulting inthe thickening of the synovial lining, formation of pannus, and erosion of cartilage and bone [40] The K/BxN serum transfer
Ngày tải lên: 09/08/2014, 10:20
... crisis focuses on the transmission and not the resolution of the crisis Therefore, the main contribution of the thesis is to offer new theoretical and empirical insight on the role of a centralised ... than the United States Hence, if there was evidence of the operation of bank lending or broad credit channel in the United States, then the magnitude of amplification of shocks through the bank ... that an understanding of the empirical studies carried out in other parts of the world is beneficial for several reasons First, these empirical studies test the validity of the theoretical framework
Ngày tải lên: 12/09/2015, 08:18
Internal audit activities in Vietnam with the resolution of the XIII congress of the communist party of Vietnam
... discussing the documents submitted by the 12th Party Central Committee, a Resolution was issued in which: Approving the basic contents of the evaluation of the implementation of the Resolution of the ... documents: The author reads, researches and quotes the content of the Resolution of the 13th Party Congress; Decree 05/2019 of the Government and legal documents related to Internal Audit; The author ... these meanings of the Internal Audit, the implementation, which is chaired by the Ministry of Finance, will contribute to the implementation of the orientation of the main targets of socio-economic
Ngày tải lên: 05/02/2024, 23:24
báo cáo khoa học: " High resolution melting analysis for the detection of EMS induced mutations in wheat SbeIIa genes" doc
... 4reaction Analysis of the melt curve of the amplicon alsoallowed the specificity of the PCR to be confirmed Although the presence of the mutation has been detected comparing theΔF/T curves (Figure ... [14] The ability to silence all copies of targeted genes through the use of RNA interference (RNAi) has per-mitted the elucidation of the role and functionality of the two different SBEII isoforms ... 5SBEIIa-D(A201T) the amino acid change induced by theEMS treatment is located in the region of the N-term-inal domain of the glycogen branching enzyme family, reported to be essential for the size of the
Ngày tải lên: 11/08/2014, 11:21
Resolution of multiparty construction disputes under the singapore international arbitration legal framework
... arbitration frees the parties from referring their case to a national court where the parties have no influence on the selection of the judge The influence of the parties in the selection of the arbitrator ... arbitration law of their choice so long as the national law of the place of conduct of arbitration gives effect to that choice The possibility of the multiparty conduct of arbitration falls under the category ... the selection of other national laws to govern the procedure of arbitration in their state For example, see Article 1493 of the French Code of Civil Procedure 13 Save for chapter VIII of the
Ngày tải lên: 09/09/2015, 10:10
AN1050 a technique to increase the frequency resolution of PICmicro® MCU PWM modules
... level that is proportional to the duty cycle Either way, the duty cycle of the PWM signal determines the level of system output while the frequency remains fixed The typical PICmicro® PWM module ... Most likely, the person doing so is engaged in theft of intellectual property • Microchip is willing to work with the customer who is concerned about the integrity of their code • Neither Microchip ... small increments around the central period register value, we can observe that the actual frequency resolution (step) provided by the CCP/ECCP module is in the range of 1 kHz RESOLUTION @ 100 KHZ
Ngày tải lên: 11/01/2016, 16:37
The joy of conflict resolution transforming victims villains and heroes in the workplace and at home
... with the other person to solve the problem If we need a villain, Trang 21THE CIRCLE OF RESOLUTIONInterestingly, the circle and triangle intersect not at the three corners of the triangle but in the ... “The one you’re not a member of,”smirks the other to the guffaws of the rest The red-faced intruder moves to another table A long-term employee appears at the door of the human resources manager ... reinforces the helplessness of the victim we are rescuing and further entrenches the other person in the villain role — thus unwittingly perpetuating the conflict (and the drama) THE VILLAIN
Ngày tải lên: 20/01/2020, 09:19
The joy of conflict resolution transforming victims villains and heroes in the workplace and at home
... with the other person to solve the problem If we need a villain, Trang 21THE CIRCLE OF RESOLUTIONInterestingly, the circle and triangle intersect not at the three corners of the triangle but in the ... “The one you’re not a member of,”smirks the other to the guffaws of the rest The red-faced intruder moves to another table A long-term employee appears at the door of the human resources manager ... reinforces the helplessness of the victim we are rescuing and further entrenches the other person in the villain role — thus unwittingly perpetuating the conflict (and the drama) THE VILLAIN
Ngày tải lên: 03/03/2020, 10:36
The joy of conflict resolution transforming victims villains and heroes in the workplace and at home
... with the other person to solve the problem If we need a villain, Trang 21THE CIRCLE OF RESOLUTIONInterestingly, the circle and triangle intersect not at the three corners of the triangle but in the ... “The one you’re not a member of,”smirks the other to the guffaws of the rest The red-faced intruder moves to another table A long-term employee appears at the door of the human resources manager ... reinforces the helplessness of the victim we are rescuing and further entrenches the other person in the villain role — thus unwittingly perpetuating the conflict (and the drama) THE VILLAIN
Ngày tải lên: 15/08/2020, 11:14
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E
... tumor content of 80% and showed no pigmentation Therefore, the failure of amplification of the 163 bp frag-ment for Sanger sequencing and HRM is rather due to the high degradation of FFPE-used ... under the cutoff defined for our study (case 30) The therascreen® BRAF Pyro Kit sequences in the re-verse direction starting at codon 600 of theBRAF gene Therefore, mutations downstream of codon ... 600 of 16.3% Halait et al even showed that the cobas® 4800 BRAF V600 test failed to detect 19% of the mutations occurring in codon 600 of the BRAF gene [45] In the study of Curry et al 82.3% of
Ngày tải lên: 05/11/2020, 01:56
Assessing the feasibility of increasing spatial resolution of remotely sensed image using HNN super-resolution mapping combined with a forward model
... spatial resolution From the super-resolution land cover m ap at the first iteration, an estim ated MS im age (at the sub-pixel spatial resolution) is then produced using a forw ard m odel and the ... the im provem ent o f the algorithm for increasing the spatial resolution o f M S im age using H N N with a forw ard m odel to the original im age The boundaries o f ponds in the centre o f the ... observed and synthetic M S im ages, an error value is produced to retain the brightness value o f the pixels o f the original M S image The process is repeated until the energy function o f the HNN is
Ngày tải lên: 18/01/2021, 18:31
THE AMBIGUITY IN THE TEACHING OF LISTENING COMPREHENSION
... the Vietnamese way of address stares with the name of nation first, the city and the street, then the name of the individual It shows that Viet Nam is built upon the premise of the value of the ... ignored in the teaching of listening comprehension The realization of the characteristic of the ambiguity and the basic method of identification of ambiguity will improve the ability of student`s ... complexity and the unavoidable situation of Ambiguity, and idiomaticalness is the key of knowing the pure information of Ambiguity The logic of people`s thought governs idiomaticalness that is the inter
Ngày tải lên: 05/06/2022, 20:28
THE OFFICE OF APPEALS AND DISPUTE RESOLUTION
... appealed the Order of Conditions to MassDEP, which issued the SOC approving the project They subsequently appealed the SOC to the Office of Appeals and Dispute Resolution, for de novo review The following ... 1410 to the back of each lawn area where it will then accumulate and travel southerly in a grassed swale across the back of Lot 10, then across the back of Lot 9, and finally across the back of Lot ... 2Capital, the project is one phase of a much larger residential development located upgradient andon the other side of the stream The larger development is known as the Salisbury Hill development The
Ngày tải lên: 18/10/2022, 04:52
Random Priority A Probabilistic Resolution of the Tragedy of the Commons
... whether or not to stay; the first in the line is offered the best lot, and in general the next agent in the line is offered the best nonassigned lot, with the understanding that she keeps the ... consists of assigning oneworker to one lot for one unit of time (a day of work) All workers are equally skilled and, at the end of the day, they have extracted all the potatoes in the lot to which they ... users) at random, and the agent who decides to buy the q-th unit pays the marginal cost of producing this very unit The only intervention of the mechanism bears on the choice of the probability distribution
Ngày tải lên: 18/10/2022, 13:08
OGC MEDIATION HANDBOOK A Guide to the Office of General Counsel’s Dispute Resolution Program
... solving. NOW, THEREFORE, I, Mark S Schweiker, Governor of the Commonwealth of Pennsylvania, by virtue of the authority vested in me by the Constitution of the Commonwealth of Pennsylvania and other laws, ... At no time will the mediator represent either of the parties or provide legal advice or any counseling to either party What is the Role and What are the Rights of the Parties? The parties come ... 8Commonwealth of PennsylvaniaOffice of General CounselDispute Resolution Program 2 What are the benefits of mediation? Because the mediator helps the parties come up with their own ideas for resolving their
Ngày tải lên: 18/10/2022, 14:53
Working It Out Together Teaching the Steps of Conflict Resolution to Preschoolers
... intended purpose of the conflict tally was to provide data on the number of conflicts and type of resolution: whether students were able to resolve the conflict on their own or if they required ... throughout the day On the conflict observation form I recorded the date and approximate time of the conflict, the participants’ initials and ages, the source of the conflict, how the conflict ... study the child often used power assertion; however toward the end of the year, his primary strategy was negotiation He also required more guidance from the teacher at the beginning of the year
Ngày tải lên: 30/10/2022, 12:43
The Role of Women in International Conflict Resolution
... further understand the impact and power of women during times of international conflict, it is beneficial to more thoroughly analyze the role of the women for peace in Liberia The influence of these ... attention to the atrocity.50 The tremendous endeavor of these women to fight against the war and to be actively involved in the peace process culminated in Taylor’s exile, the end of the war, and the ... with the rebel organization the National Patriotic Front of Liberia (NPFL), had seized control of most of the county and had besieged the capital of Monrovia.54 The most powerful warlords of Liberia
Ngày tải lên: 30/10/2022, 16:21
cluster observations of the substructure of a flux transfer event analysis of high time resolution particle data
... space-craft in their orbit, the projection of their positions on the XZ, XY , and Y Z planes are shown in the top row of panels of Fig 1, in the GSE coordinate system The projections ofthe four spacecraft ... from ∼ −15 nT at the start of the period shown to ∼ 0 nT by ∼10:00 UT The values of this component have an offset of ∼ −7 nT for C2, which may be related to the separation of thefour spacecraft ... significant change in the magnetic field strength (variance 5 nT) Assuming that the signatures described above at each of the three spacecraft are of the same event, then the simultaneity of the signatures
Ngày tải lên: 01/11/2022, 09:12
a high resolution capacitive sensing system for the measurement of water content in crude oil
... as: The capacitance of glass wall (Cw) is dependent on the dielectric material of the glass and is a constant, while the actual capacitance (Ca) is proportional to the dielectric constant of the ... electrode, εo is the dielectric permittivity of free space, εa is the dielectric permittivity of sample inside glass tube, d is the minimum distance between the electrodes, R is the radius of the tube ... values of Ψ The simulation results are shown in Figure 8 The results show that lower values of Ψ give higher sensitivity but at reduced linearity The selection of Ψ therefore depends on the range of
Ngày tải lên: 02/11/2022, 08:50
Development of a liquid chromatography high resolution mass spectrometry method for the quantitation of viral envelope glycoprotein in ebola virus like particle vaccine preparations
... adenosines at the editing site most of the time (>80 %), and these transcripts result in the expression of the predominant GP gene product, secretory glycoprotein (sGP) [12] The addition of 2 adenosine ... describes the development of an isotope dilution full scan LC-HRMS method for the absolute quantitation of Ebola GP1 in eVLP The protocol resulted in the quantitation of GP1 with a lower limit of quanti-tation ... analyzed The purified rGP1 standard was digested using the same protocol as the eVLPs with the exception that the concentration of the trypsin/lys-C was reduced fourfold Quantitation of GP 1 by LC‑HRMS
Ngày tải lên: 24/11/2022, 17:39
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