the message of a master

... membrane To determine whether the L42R mutation changes the conformational state of PTENA4 and ePTEN, we performed an “in trans” interaction assay; binding of GFP-tagged PTEN variants to a separate ... from the plasma membrane (A) Associations between the core region (e.g the phosphatase and C2 domains) and the tail of the same PTEN molecule (closed conformation) are maintained through the ... Trang 1Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN Hoai-Nghia Nguyen, Jr-Ming Yang, Takafumi Miyamoto, Kie Itoh, Elmer Rho, Qiang Zhang,

Ngày tải lên: 04/12/2022, 16:02

... top of the tank It is originated from the fact that, after gaining heat from the solar radiation, the tank wall heats a thin vertical layer of water along the tank wall Part of this heat is then ... initial and mass-weighted average temperatures of water; with all the values, apart from the mass-mass-weighted average temperature, are the same in both studies Accordingly, a parameter equals to the ... actual performance of a large capacity integrated collector storage solar water heater in the shape of a right angle prism-shaped tank covered with glass during several months of the year The heat

Ngày tải lên: 05/09/2013, 15:28

... support to MFIs amongst lower income populations The data was tabulated and analyzed through qualitative analysis of the gathered data, which reveal the behaviors and decision making patterns in lower ... including educational, communal, cultural, political and economic facets The questionnaire also evaluated the level of awareness about MFIs, availability and accessibility to MFIs, and impact of Government ... Bangladesh, Zambia and Bolivia, it can be inferred that such initiatives can also encourage small and medium sized profitable business establishments in the rural and remote areas of Pakistan

Ngày tải lên: 06/09/2013, 05:48

... pairs of Ca atoms < 2.5 A˚ apart Because of the different length of a helix A, the Caatoms N-terminal to or inside helix A are separated by large distances The corresponding region in AppA ... substrate recognition For the superposi-tion of the substrate-free PhyK with substrate-free AppA the Caatoms are 2.41 A˚ apart, whereas for the substrate-free PhyK and the substrate-loaded AppA the ... human PAP does not con-tain the b-hairpin motif present in PhyK as well as in AppA and G1P The a⁄ b domain of HAPs is evolutionarily more conserved than the a domain For example, the phytase of

Ngày tải lên: 16/02/2014, 09:20

... on the same terms as the other clerks, the fatherhad barred that form of address in bankinghours "Mr Bagsbury," John began again, and now the words came easily, "I was offered another ... wouldpause and wait for the wind to blow the refractory lock out of the way again Then she would laugh, for it wasall part of the lark to Dick, and start on In one of these pauses she saw a little ... pinch.That was the trouble over at the other place They got scared and let go of me once in a rather tight place, afterthey'd told me that they'd see me through The collateral I offered them was all

Ngày tải lên: 17/02/2014, 19:20

... on data for the last 50 years would be only a starting point The nature of modern warfare and modern casualty treatment options have changed the ratio and cost of deaths and disabilities drastically ... and are not considered costs of current military person-nel Instead, DoD pays an annual accrual charge into the trust funds These accrual charges are carefully calculated actuarial payments that ... by the Department of the Treasury From the standpoint of the FG, accrual is therefore not a cost at all but rather an intragovern-mental transfer payment—the movement of money from one budget account

Ngày tải lên: 17/02/2014, 23:20

... the worst ofthe bargain Trang 38The news of the disturbance had reached the barracks shortly after the two factions had met, and such of thesoldiers as were at that time within the barrack walls ... Moors by Spanish kings There is no Seville Cathedral, no Giralda There is no Alhambra as there is in Granada There are only parts of theancient walls that enclosed the old city The Moors apparently ... with the Army His presence was a source of embarrassment to the High Command Trang 22I was able to be present at the retreat of the Carlist troops from the blockade of Pamplona, as well as thecapture

Ngày tải lên: 18/02/2014, 06:20

... mitochon-drial respiratory chain, the assistance of specific chaperone proteins is also required The available data indicate that the accessory factor Bcs1p is involved in the binding of ISP to an immature ... the midst of this quickly evolving con-text of macromolecular organization of the mitochon-drial proteome, comparatively little is known about the assembly pathway leading to the maturation of ... supercom-plex and the TIM23 machinery [22] and the second reporting the influence of the ATP synthase complex on the assembly state of the bc1-oxidase supercomplex and its association with the TIM23 machinery

Ngày tải lên: 18/02/2014, 08:20

... Vaaje-Kolstad et al containing 100 lm of (GlcNAc)1–4 was analysed at the start, in the middle and at the end of each series of samples The resulting average values of the standards (displaying standard ... instructions, containing ends compatible with the expression vector (forward primer, 5¢-GGTATTGAGGGTCGCCATGGTTATGTTC AATCACCA-3¢; reverse primer, 5¢-AGAGGAGAGTTAG AGCCTTACAAGAAGGGTCCAAAGA-3¢) The PCR product ... hydrolases) was recorded at regular time intervals The degradation of a-chitin by LlChi18A started with a rapid phase, regardless of the presence of LlCBP33A In the presence of LlCBP33A, the fast

Ngày tải lên: 18/02/2014, 08:20

... dextran-a-CT conjugates at pH 7.1, 25 C. (kcalÆmol)1) Lac-a-CT a Dex-a-CT a a Average moles of lactose and dextran per mole of a-CT b Aiare the fractions of amide protons in the i th population ... equal to k cat for the hydrolysis of Suc-AAPF-SBzl. Lac-a-CT Dex-a-CT Trang 8were independent of the size of the glycan (Tables 2and 5, [36]) The analysis revealed that the changes in these parameters ... order based on the calculated electrostatic pot-entials (EP) for the N e of the lysine residues of a-CT at pH 9 EP, EwaldEi EP is the Ewald energy of placing a charge of +1 at the location of the

Ngày tải lên: 19/02/2014, 05:20

... in the topic Pastry and Scribe are fully decentralized, all decisions are based on local information, and each node has identical capabilities Each node can act as a publisher, a root of a multicast ... result, application-level multicast is gaining popularity Appropriate algorithms and systems for scalable subscription management and scalable, reliable propagation of events are still an active ... entries, where each entry maps a nodeId to the associated node’s IP ad-dress Moreover, after a node failure or the arrival of a new node, the invari-ants in all affected routing tables can be restored

Ngày tải lên: 19/02/2014, 18:20

... structure of the PSII core of Thermosynechococcus vulcanus, have a role in the stabili-zation of the Mn cluster and of its ionic cofactors Ca2+ and Cl–, and also in the overall (thermo)stability of ... second-derivative spectrum [43], as follows: a¼ ðrn raÞ=ðru raÞ where rn and ru are the experimentally determined numerical values of the ratio a/b, and rais the theoretical numerical value of ratio a/b ... samecharacteristics of the interior of the protein matrix The script a is the peak–peak distance between the maximum at 287 nm and the minimum at 283 nm, and the script b is the peak–peak distance

Ngày tải lên: 21/02/2014, 00:20

... 1997) and the International Plant Names Index database except Leguminosae sensu lato, which follows the subfamily categorization of Mimosaceae, Fabaceae sensu stricto and Caesalpiniaceae The study ... district, the main species for plantation establishment are Acacia auriculiformis, Acacia mangium and Pinus kesiya, selected by project managers of the national forestry programs The total area under ... illegal) still occurs An old cemetery is situated in the middle of an Acacia plantation, and the remains of abandoned villages can be found around the small tree forest in the village area These

Ngày tải lên: 21/02/2014, 04:20

... and make their devotions, seeking the protection of Trang 7the patron saint of the city The head alcalder of the city was a Castilian Spaniard, a venerable-lookinggentleman, white as any Northern ... inquired of the captain about the history ofthe vessel He said she had been built at Quavqiel, down the coast, and had belonged to a Mexican general,and was built partially of an American whaler that ... United States over California Thecaptain and crew were aboard The captain was an Englishman; the crew, cosmopolitan a Hindostan, aMexican named Edwin Jesus, an English sailor and an American I inquired

Ngày tải lên: 21/02/2014, 14:20

... In the morning a large tub of water was carried in and each man was given a bit of black bread and a slice of raw fat bacon The latterwas salty and so thoroughly unappetizing that I cannot recall ... up and down the lane, watching for any relaxation or levity If so much as a face was pulled at a twinkling eye across the way, another day's strafingwas added to the penalty At the end of the ... yards away in Belle-waarde Wood and in front ofthe château and lake of that name, where my draft had lain on the fourth I made a dash for it What with themud and the many shell holes, the going was

Ngày tải lên: 21/02/2014, 21:20

... 5¢ TAG TTC AAA TGC ACA TCT TAT 3¢ C14U 5¢ GGC AGA GAA TAC GTT TAT ACT AA 3¢ C14L 5¢ TCT CAG ATT GAC TAC TAC AAC TT 3¢ C15U 5¢ CAT GAA AAG CAT TTC AAA AA 3¢ C15L 5¢ TAA AAA ACA GTG GTT ACC AA 3¢ ... CAA GTT TAT AGT CTA CAC GTT GTA C 3¢ C19U 5¢ CTT AGC ATC TTC CAT GGC TTG ATC 3¢ C19L 5¢ ATA CAC ACA AAC TCA CAA GG 3¢ MWU 5¢ CAA CAT ATT TTA AAT AAA ATT GAC AAT 3¢ C9LM* 5¢ ATA AAA ATG GTA TAC ... CAT AAA ACT AAC AAT ACA TGT 3¢ C1011L 5¢ TAG CAG ATA TTG AAA AGG AG 3¢ C12U 5¢ CCA GTG AAT ATT CAG GAC TGA T 3¢ C12L 5¢ AGG CTC TAG CAT GAT TTG ATG T 3¢ C13U 5¢ GCA TTT TTA TTT TGA ATG TAA A

Ngày tải lên: 22/02/2014, 04:20

... laying claim to.” In actuality, this conversation never took place Because of the weather, seating was abundant and the table next to us that evening was empty And it was because of the weather ... without warning and the first concrete barri-cades installed a few days later In addition to the inaccuracy of referring to the two walls as a singular entity, to speak of the Wall as simply a wall ... function As a physical manifestation of the Iron Curtain, the Wall veniently fit the Cold War narrative Its fall brought with it the collapse of the East German state, the return of a uni-fied Germany,

Ngày tải lên: 22/02/2014, 06:20

... Malaysian coastal and marine resources off the Straits of Malacca and the adjacent waters of the Andaman Sea and the Indian Ocean In the process, an attempt is made to identify, examine, and rank those ... Kalimantan Kuala Lumpur, the national capital, Labuan Trang 12and Putra Jaya form the Federal territories The multiracial population of Malaysia is composed of 58 percent bumiputra (Malays and ... 20.46% of the total land area Penang, Selangor, Malacca, and Perlis have population densities that are multiples of the national average Trang 31Table 2.6: Population by State - Malaysia (2000)

Ngày tải lên: 06/03/2014, 15:21

... Copies of working papers are available from the author The Impact of a Corporate Culture of Sustainability on Corporate Behavior and Performance Robert G Eccles, Ioannis Ioannou, and George Serafeim ... Ioannis Ioannou is an Assistant Professor of Strategic and International Management at London Business School George Serafeim is an Assistant Professor of Business Administration at Harvard Business ... companies), compete on the basis of brands and reputation, and make substantial use of natural resources These results have implications for investors that integrate environmental and social data

Ngày tải lên: 06/03/2014, 20:21

... said: the great masses of humanity are using the Law destructively, or partially so, and the scales are balanced against them. Here and there, among the masses, we find an occasional outstanding ... as the beasts of the field, the birds of the air and the fish of the sea are bountifully supplied. For any man, no matter what his station in life, to take the stand that it is the destiny of ... that I had met my deliverer, and at the close of the performance was overjoyed at his invitation to accompany him to a nearby café. I noticed that the attention of those in the café was drawn...

Ngày tải lên: 15/12/2013, 06:15