... per-formance of a clinical system to be most effective, they must take into account not only the nature of the sys-tem, but also the nature of the disease The purpose of this paper is twofold First, ... impact of the nature of the disease on the types of interventions that are more likely to be effective Methods: We conducted a systematic review of the literature between 1998 and 2008 of organizational ... characteristics of the organization be considered, but so must the characteristics of the disease and its treatment Interventions must be appropriately matched to the level of complexity of not only the
Ngày tải lên: 10/08/2014, 10:23
... Department of Health Risk Analysis and Toxicology, Maastricht University, the Netherlands Colorectal cancer is the third most commonly diagnosed cancer in the world and is one of the major causes of ... absorbed in the intestinal tract, and reach the colon mainly intact [27] They are therefore bio-available to the epithelial cells in the intestinal wall, where procyanidins and other phenolics ... investigated the relationship of different structural factors of procyanidins, such as the mean degree of polymerization and percentage of galloylation, with their antiproliferative potential and their
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis doc
... on the basis of their model of human CPU, that the two consecutive I at positions 204 and 205 are exposed to the surface, and because they are quite unique to CPU, might be of importance for the process ... to the manufacturer’s instructions Expression of mutant proCPUs in insect cells Determination of the half-life (T1/2) of CPU s activity The T1 ⁄ 2 of the activity of the ... combinations increased the stability of CPU’s activity, especially the YQ mutant. Following the first round of FIND TM treatment, 50% of the mutants with improved thermal stability of their activity appeared
Ngày tải lên: 07/03/2014, 12:20
Research " A Comparative Study of returns to education and the Importance of Genetic and Environment Factors: Evidence from Different twins data " ppt
... determine the genetic traits of the resultant individual As a result of the random matching, each pair of genes in a fertilized egg consists of one from the father and one from the mother Assuming ... Requirements for the Degree of Doctor of Philosophy in Economics @ The Chinese University of Hong Kong May 2000 The Chinese University of Hong Kong holds the copyright of this thesis Any person(s) ... variables Given that these errors exist in the data, the use of the GLS estimation method rather than the OLS can reduce the effects of these errors Similarly, the “within family differenced reduced
Ngày tải lên: 16/03/2014, 03:20
Báo cáo khoa học: The importance of being dimeric pptx
... acids to their tRNAs and then to each other when on the polyribo- somes, one should take into account the energy con- sumed by the synthesis and preprocessing of mRNA inside and outside the nucleus, ... proportional to the gene length. Therefore, one should consider the addi- tional cost for the cell to keep the whole process under control. Another factor in favor of synthesizing dimers instead of larger ... the roughness of the monomer contact surface can be critical for the dimerization process, we have also checked for the presence of gaps and voids at the interface of the dimers. The data demonstrated
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: "The Importance of Rule Restrictions in CCG" doc
... grammar G T that generates the yields of the set of all transformed derivations of G. As the set of terminals of G T , we use the set of terminals of G . To form the set of nonterminals, we take ... happens to the proof of The- orem 1 in the context of pure B&K-CCG . There is only one point in the entire proof that could be damaged by the introduction of slash types, and that is the result ... category j y, plus the arguments of x. We number the arguments of a category from outermost to innermost. The arity of a category is the number of its arguments. The target of a category c is the atomic
Ngày tải lên: 16/03/2014, 23:20
The Importance of Water and Water Quality in Brewing pptx
... associated with sulfate ions In the presence of sulfate, sodium creates an unpleasant harshness, so the rule of thumb is that the more sulfate in the water, the less sodium there should be (and vice ... ChemistryAlkalinity in the Brewhouse: Alkalinity is a measure of the buffering capacity of the bicarbonate ions and, to some extent, the carbonate and hydroxide ions of water These three ions all ... of hard water, and facilitate the reduction of the Trang 17Water and TaintWater is a common source of Taints in beer Typically, water is the source of the majority of taints associated in beer:
Ngày tải lên: 18/03/2014, 00:20
Báo cáo khoa học: Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence doc
... packing of TM1 with the other helices, causing a slight shift of TM1 relative to the rest of the bundle (Fig. 3A). At the same time, the main kinks in the TM helices of rhodopsin (e.g. the functionally important ... The lower binding affinity of the receptors in the ER may be the result of several mechanisms: (a) the cholesterol content of the ER membrane is different from that of the. ... preserved in the 3D model of C5aR. Also, the 3D model of the TM bundle of C5aR differed from the recently published X-ray structure of the b 2 -adrenergic receptor [4,5] by a rms value of only 2.69
Ngày tải lên: 23/03/2014, 04:21
Báo cáo khoa học: Structural determinants of protein stabilization by solutes The importance of the hairpin loop in rubredoxins pdf
... accommodate the conserved structural features. Overall, the structure of the mutant retains the main features of the native structure with the obvious excep- tion of the loop region. The RMSD between the ... some of these residues (Fig. 3). In particular, the exposure of the residues that com- prise the lower part (relative to the orientation depic- ted in Fig. 2) of the hydrophobic core of the native protein, ... despite the drastic deletion; this reveals the structural importance of the other unaffected motifs in directing folding. Even with a severe disruption of the middle loop, the rest of the characteristic
Ngày tải lên: 30/03/2014, 15:20
Báo cáo lâm nghiệp: " Ranking the importance of quality variables for the price of high quality beech timber (Fagus sylvatica L.) ppt
... observed price of the test data (217.58 of the estimations for the independent data was greater It 4.2 Estimating the e ffect of timber quality variables Being aware of the great importance of the buyers’ ... for the evaluation models rather than artefacts A ranking of the importance of the timber quality variables on the basis of both models there-fore seemed acceptable Among the quality variables the ... regardless of the prediction for the main or for the independent test data set (Tab V) When compared to the performance of the model without the buyers’ preference (one-stage approach) the results of the
Ngày tải lên: 08/08/2014, 00:22
báo cáo khoa học: " Characterization of cp3 reveals a new bri1 allele, bri1-120, and the importance of the LRR domain of BRI1 mediating BR signaling" doc
... Full list of author information is available at the end of the article recently than any of the other plant hormones, the identification of BRASSINOSTEROID-INSENSITIVE1 (BRI1), a receptor of BR [3], ... found in the extracellular portion of the plasma membrane BRI1 constitutively forms a homodimer in the plasma membrane In the absence of BR, the activity of the BRI1 homodimer is inhibited by the ... BKI1 to the C-terminal portion of BRI1 In the presence of BR, BKI1 is released by the direct binding of BR to the 70-amino acid island region in the extracellular domain of BRI1 [7] Then, BRI1
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Reduction of exacerbations by the PDE4 inhibitor roflumilast - the importance of defining different subsets of patients with COPD" pps
... responsibility for the integrity of all of the data and the accuracy of the data analysis, including and especially any adverse effects DB contributed to the conception and design of these studies, the acquisition ... final approval of its content ahead of submission U-MG contributed to the conception and design of these studies, the acquisition of study data, and the analysis and interpretation of these data. ... conception and design of these studies, the acquisition of study data, and the analysis and interpretation of these data He was fully involved in the drafting and revision of this manuscript, and
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps
... against the consen-sus sequence of the known transcripts for the target gene Microarrays carry multiple probes against the same gene dis-tributed throughout the length of the transcript, some of which ... to the standard One-cycle method on 11 out of 12 quality control parameters tested There was a small bias in the 3'/5' ratio of some genes caused by the generation of shorter products from the ... example of annexin V staining of cancer and normal prostate cells in response to an 18 hour Nested RT-PCR for the detection of the TMPRSS2:ERG fusion Figure 2 Nested RT-PCR for the detection of the
Ngày tải lên: 14/08/2014, 08:21
LUẬN MẪU LỚP 12 The importance of the newspaper
... a lot of harm On the other hand,if the policy of the newspaper is to promote the welfare of thepeople, it could do a lot of good For example, it could exerciseits influence to persuade the government ... Trang 1 The importance of the newspaperThe newspaper, today, plays a vital role in human affairs Itsimportance has not been diminished by the appearance of theradio or the television ... of the famous leaders of the world We are alsoable to see some of the great events of the day In addition, wecan get news from all parts of the world, and listen to songs andmusic Sometimes there
Ngày tải lên: 15/07/2015, 23:18
LUẬN MẪU LỚP 12 The importance of rivers
... are written just for the pleasures of the mind Indeed, the variety of books is infinite One of the reasons for the existence of such a wide variety of books is that the field of knowledge is very ... a means of communication for the goods that they transport from place to place Early civilization began on the banks of the great rivers of the world, such as the Nile and the Indus These rivers ... among the peoples of the world Today there are hundreds of newspapers all over the world Everywhere there is a keen desire to learn more and more about the affairs of the world This is partly the
Ngày tải lên: 15/07/2015, 23:18
LUẬN MẪU LỚP 12 The importance of good roads in a country
... festival a success This is the time for the men, women and children of the village to wear their best clothes and the village is full of colour These simple ways of life in the village, Trang 4however, ... seen playing the popular games of the village Occasionally, a cyclist passes by Then, in the evening, the villagers meet one another Some play cards and other types of games peculiar to the village ... In the afternoon, most of the villagers are at home Some of them take a nap after lunch; some work in their small gardens, and some visit the small shops in the village In various parts of the
Ngày tải lên: 15/07/2015, 23:18
Modeling the importance of biomass qualities in biomass supply chains for bioenergy production
... each of the four plants were fixed instead of biomass being the function of amount of energy productions. This was modeled such as the information available at the time was constrained. The main ... adapted to the similar cases elsewhere. Hence, the importance of this work is of global nature in the era of emerging sustainable energy development around the globe in order to mitigate the GHGs ... two types of biomass distributed over the productive forest cells derive the total biomass requirement to produce bioenergy at the capacity levels of each power plant. The end results of the entire
Ngày tải lên: 09/09/2015, 10:32
THE IMPORTANCE OF DEVELOPING AND LAUNCHING PRODUCTS
... market, are clear evidences to the importance of the development and the presence of new products Trang 11PART II RATIONALEI The importance of developing new products 1 The product life cycle Like ... help businesses improve and confirm the role andposition themselves in the market Therefore, the development and launch ofthe product as well as the expansion of the market is an important activity ... complained about the lack of novelty of Vietnamese products Around the world, in addition to the tremendous success of Apple, Samsung is the failure of Blackberry, and Nokia in the smartphone market,
Ngày tải lên: 11/09/2015, 08:13
A STUDY ON THE IMPORTANCE OF LEARNER IDEAL SELF TO THE SUCCESS IN LEARNING ENGLISH OF THE LEARNERS AT THE BORDER GUARD ACADEMY
... 2 2 Aim of the study 2 3 Objectives of the study 2 4 Research question 2 5 Scope of the study 2 6 Methods of the study 2 7 Significance of the study 2 PART B: DEVELOPMENT 2 CHAPTER 1: THEORETICAL ... success I immediately came up with the idea of doing a study of the importance of the Learner Ideal Self to the Success in Learning English of the Learners at The Border Guard Academy It is unarguable ... done for the purpose of finding out the role of the learner ideal self in the success in learning English of the learners at the Border Guard Academy Depending on the research result, the teachers
Ngày tải lên: 14/09/2015, 09:29
THE IMPORTANCE OF AN ALLOSTERIC POCKET IN THE DENGUE PROTEASE
... to fusion of the viral and the cell membrane (Figure 1.5 (3c)) The nucleocapsid is then released into the cytoplasm and replication of the RNA genome is initiated after dissociation of the capsid ... by residues of both NS2B and NS3 The goal of this study is to assess the functional importance of this pocket by mutating selected residues lining the pocket Enzymatic activities of the recombinant ... are formed in the lumen of the ER and later released into the trans-Golgi network (TGN) Cleavage of the prM protein (Figure 1.5 (7c)), mediated by the host-cell protease furin in the TGN, creates
Ngày tải lên: 02/10/2015, 17:13
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