the head and neck

... using the SCC4 cells Top graphs: the data were presented as the fold difference between the SP and MP cells in the number of migrated or invaded cells The values represent the mean ± standard ... at 450 nm The data of the SP and MP cells were separately presented as follows: the data on day 1 were defined as 1.0, and those on day 2 and 3 were defined as the fold increase in the respective ... added to the bottom of wells as a chemoattractant The inserts for the migration and inva-sion assays were incubated for 24 h and 48 h, respectively, at 37 °C The filters were removed, and then cells

Ngày tải lên: 22/09/2020, 23:50

... association of MMPs and TIMPs and the possible therapeutic aspects of these proteinases in potentially malignant and malignant head and neck lesions So far, no promising drug target therapy has been ... the head and neck is a multi-step process Head and neck malignancies consist of a heterogeneous group of neoplasia They constitute the sixth most common malignancy, and more than 90% of these malignancies ... to their ability to degrade the ECM and basement membranes [24] Regulation of MMPs in potentially malignant and malignant head and neck lesions The MMPs are regulated at many levels [21] The

Ngày tải lên: 10/08/2014, 05:21

... synthesized the radiotracers RG was responsible for recruiting patients and participated in the design of the study OS and HM participated in the design and coordination of the study and helped draft and ... studies and participated in the coordination of the project KOS, PK and JL were responsible for histology and immunohistochemical analyses, drafting and correcting the manuscript. OE and TV synthesized ... between the expressions of HIF-1 α and GLUT-1 (A) The expression of p53 showed a negative correlation with the expression of GLUT-1 (B) and the amount of apoptosis with Ki-67 (C) Furthermore, the

Ngày tải lên: 14/10/2020, 13:08

... parameter in the interpretation and rendering of diagnostic decision algorithms for in vivo tissue diagnosis and characterization in the head and neck Further, we also explored the utility of ... Box charts of the 5 PCA scores for the different tissue types (i.e., PN, FOR and LVC) The line within each notch box represents the median, but the lower and upper boundaries of the box indicate ... measurements in the head and neck We carried out the transnasal image-guided Raman endoscopy for the first time to directly assess distinctive Raman spectral properties of nasopharyngeal and laryngeal

Ngày tải lên: 09/09/2015, 10:09

... 2002) stage and treatment plan Additionally, radiotherapy dose, number of fractions and the start and end date of radiotherapy were recorded for each patient The pre-treatment neutrophil and lympho-cyte ... including other head and neck associated cancers, such as thyroid cancer [42, 43] The association between NLR and poor OS and recur-rence is not well understood However, it is hypothesised that ... multidisciplin-ary head and neck tumour board, which included oto-laryngology surgeons, radiation oncologists and medical oncologists who assigned the tumour stage and subse-quent management The patient

Ngày tải lên: 21/09/2020, 11:23

... of the head and neck (SCCHN) Background Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer and also the most com-mon tumor type in the head and neck region The ... to the promoters of the p63 gene ChIP/PCR analysis of WT1D transfected and non-transfected FaDu cells A PCR analysis of the precipitate using p1, p2 and p3 primer pairs Size and location of the ... LB and XG. KN contributed the materials, reagents and analysis tools The manuscript was written by XL, SO, SW and AL All authors were involved in revising the manuscript All authors read and

Ngày tải lên: 29/09/2020, 16:23

... with head and neck cancer patients The FACT-HN consists of a 27-item core scale (FACT-G) and is supplemented with a 12-item head and neck subscale targeting head and neck related symptoms and ... and DLQI will be administered a baseline and at 3, 12, and 24 months after the start of radiation therapy 1.7.2 Timeframe of Assessments These patient-reported QOL and function measures and the ... including: the FACT HN and the Dermatology Life Quality Index (DLQI) Both of these QOL validated tools are currently being used by the RTOG in SCCHN trials, and the FACT HN is being used in the UCCI

Ngày tải lên: 18/10/2022, 13:06

... Kamada T, and the Japan Carbon Ion Radiotherapy Study Group, A Multicenter Study of Carbon-Ion Radiotherapy for Mucosal Melanoma of the Head and Neck: Sub-analysis of the Japan Carbon-Ion Radiotherapy ... affect the content, and all legal disclaimers that apply to the journal pertain. Trang 2A Multicenter Study of Carbon-Ion Radiotherapy for Mucosal Melanoma of the Head and Neck: Sub-analysis of the ... Of these, 268 patients (excluding choroidal melanoma) had a pathological diagnosis of malignant melanoma The primary sites were the head and neck mucosa in 260 patients, the orbit in 6, and other

Ngày tải lên: 19/11/2022, 11:40

... of the parotid gland doses The planning target volumes and both parotid glands, the mandible, and the larynx were outlined on the transversal slices of the planning CT-scans The planning goal ... tomographies of the parotid glands Trang 4gland dose and the tumor site were the independent determinants 12 and 36 months after the end of RT Patients of group I and II parotid gland function ... circumstances that the protection of at least one single parotid is achieved either with 3D-CRT and IMRT Depending on the radiation dose to the salivary glands the time of recovery of the parotid glands should

Ngày tải lên: 09/08/2014, 09:21

... of head and neck lesions. about the editor LEON BARNES is Professor of Pathology and Otolaryngology, Chief of the Division of Head and Neck– Endocrine Pathology and Director of the Head and Neck–Endocrine ... Head and Neck Tumors, and is the editor of the two previous editions of Informa Healthcare’s Surgical Pathology of the Head and Neck. Printed in India H9163 Trang 2Pathology of the head and neck ... SSurgIcal PaThologY of ThE hEaD anD nEck BARNES Surgical Pathology of the Head and Neck, Third Edition is a complete stand-alone reference covering all aspects of head and neck pathology Providing

Ngày tải lên: 20/01/2020, 13:56

... cartilage involvement and does not specifically address cutane-ous SCC of the head and neck Accordingly, this system is inadequate for SCC of the head and neck and for use in patients in the high-risk ... melanomas at other body sites Additionally, lentigo maligna melanomas are more common on the head and neck than other sites, and, of head and neck melanomas, nodular melanomas are more common on the scalp ... presents on sun-exposed surfaces, most commonlythe head and neck and dorsum of the hands, althoughthe trunk and extremities have been described (208).The classic age distribution is in patients

Ngày tải lên: 21/01/2020, 13:07

... of head and neck lesions. about the editor LEON BARNES is Professor of Pathology and Otolaryngology, Chief of the Division of Head and Neck– Endocrine Pathology and Director of the Head and Neck–Endocrine ... PaThologY of ThE hEaD anD nEck BARNES about the book… Surgical Pathology of the Head and Neck, Third Edition is a complete stand-alone reference covering all aspects of head and neck pathology ... Head and Neck Tumors, and is the editor of the two previous editions of Informa Healthcare’s Surgical Pathology of the Head and Neck. Printed in India H9165 Trang 2Pathology of the head and neck

Ngày tải lên: 22/01/2020, 10:24

... 5 4 5 % of neurilemomas present in the head and neck, with the lateral neck being the most frequent site (8-9) The spinal roots and the cervical sympathetic, and vagus nerves are commonly involved ... extremities and shoulder girdle (1.2,6-13,15,17,18) Only occasionally have they been reported i n the head and neck region (8,10.18-21) Of the tumors reported in the head and neck, Mentzel et al and ... remaining involved the perineum (2.4%), hypophysis (2.4%) and miscellaneous sites (2.9%) (30) Common cutaneous sites in the head and neck include the forehead nose, neck and eyelids; the scalp is rarely

Ngày tải lên: 22/01/2020, 21:30

... submandibular glands and the parotid tails may abut one another in the upper neck The submandibular salivary gland lies at the posterior, free margin of the mylohyoid muscle (Fig. 2.3) Some of the gland ... the ultrasound probe in the left hand and injects the anesthetic into the lesion with the right hand (B) Observing the monitor and using the ultrasound probe for guidance, the aspirator uses negative ... within the parotid Trang 23reference to the parotid glands The size of the submandibular glands varies between individuals and in some patients (with gener-ally large salivary glands) the submandibular

Ngày tải lên: 08/09/2020, 14:36

... assess the incidence and to review experience with the treatment of mucosal melanoma of the head and neck (MMHN) in Slovenia between 1985 and 2013 Methods: The National Cancer Registry database and ... melanoma, Head and neck cancer, Epidemiology, Therapy, Survival Introduction Mucosal melanoma of the head and neck region (MMHN) was first described by Weber in 1856 and has since been the subject ... Epidemiology In the 29-year period from 1985 to 2013, MMHN repre-sented 0.5 % of all head and neck malignancies, 0.8 % of all melanomas, 4.4 % of all melanomas in the head and neck region and 42 % of

Ngày tải lên: 04/12/2022, 15:42

... Trang 1pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status Addresses: * Head and Neck Surgery Branch, NIDCD, ... factor controlling the expression of genes that affect cellular proliferation, apoptosis, angiogenesis, immune and proinflammatory responses, and therapeutic resistance in head and neck squa-mous ... NF-κB inducing kinase and IKKα modulating NFκB2 and RELB [1,2,11,24-26] Furthermore, there is potential for cross-talk between IKK/NF-κB and other major signal path-ways, such as the mitogen-activated

Ngày tải lên: 14/08/2014, 08:20

... nose, and the bregm a is the junction of the coro-nal and sagittal sutures The m axillae and m andible provide the sockets and sup -porting bone for the m axillary and m andibular teeth The m ... of the upper jaw and face Each bone form s the bulk of the oor and lateral wall of the nasal cavit y and the orbital oor It also contributes to the infratem poral and pterygopalatine fossae The ... bone and the crests of the nasal bones.4 orly, the plate articulates w ith the crest of the sphenoid body superiorly and the vom er inferiorly The broad inferior border Posteriat taches to the

Ngày tải lên: 17/11/2019, 15:04

... of the Head and Neck Trang 13 Submandibular Space The submandibular space is below the mylohyoid muscle and bordered by the carotid, sublingual, and masticator space [ 7 ] The contents are the ... larynx and, therefore, the lower edge of the subglottis The arytenoid cartilage spans the ventricle The upper arytenoid is at the level of the false fold, whereas the vocal process defi nes the ... landmark Another important landmark is the upper margin cricoid cartilage This cartilage is the only complete ring of the cartilage frame-work and thus is key to the integrity of the airway The

Ngày tải lên: 20/01/2020, 17:42

... resolution DSA remains the “gold standard” in the evaluation of the arteries and the hemodynamics We believe the gadolinium-enhanced MRV is now the “gold standard” in the evaluation of the venous system ... are exempt from the relevant protective laws and regulations and therefore free for general use The publisher, the authors and the editors are safe to assume that the advice and information ... perfusion clarifi es the extent of the damage and the territory at risk CTA in acute stroke must include the neck since many embolic strokes originate in the neck The assessment of the carotid bifurcation

Ngày tải lên: 21/01/2020, 21:20

... project; AN, Md-MR, MC and XT analyzed the data and drafted the manuscript; MC had critically read the manuscript; XT edited and reviewed the manuscript All authors read and approved the final manuscript. ... tobacco smoking and the reversal of head and neck cancer risk. Int J Epidemiol 2010;39(1):182 –96. 5 Leemans CR, Braakhuis BJ, Brakenhoff RH The molecular biology of head and neck cancer Nat ... reported in the BTB (broad-com-plex, tramtrack, and bric-a-brac) domain, 1 in the IVR (intervening region), 1 in the C-terminal, 1 in the N-terminal region, and another 4 were in the Kelch domain,

Ngày tải lên: 23/07/2020, 23:49