the generation of term definitions

... C noxiusvenom To the best of our knowledge, this is the first report of the generation of a human recom-binant antibody fragment capable of neutralizing the toxic effects of the whole venom from ... three cycles of directed evolution The use of stringent conditions in the third cycle allowed the selection of several improved clones The best scFv obtained (6009F) was improved in terms of its affin-ity ... LD50 of Cn2 toxin when a 1 : 10 molar ratio of toxin-to-anti-body fragment was used It was also able to neutralize 2 LD50of the whole venom These results pave the way for the future generation of

Ngày tải lên: 23/03/2014, 13:20

... from the most important food merchandise distribution center in the city The samplers were located on the roof of a four-story building the time of the experiment; none were smokers On the morning ... concentration of 25 mM This solution was stored in the dark at 4°C On the morning of the experiment, ml of this solution were added to the sample to give a final concentration of 100 mM The CL response ... [11] It is therefore likely that the increased air pollution and geographical characteristics of Mexico City have a significant impact on the health of the inhabitants [12,13] In view of the mechanisms

Ngày tải lên: 20/06/2014, 00:20

... on the variance of the complex Gaussian random variables at the inputs of Doppler filters as well as the characteristics of those filters. The variance value of the outputs is then input into the ... one another. Therefore, the sce- nario where the variances of the Rayleigh envelopes are equal to one another and the powers of real parts are equal to those of imaginary parts, such as the scenario ... at the output of the Rayleigh simulator may have arbitrary values, depending on the variances of the Gaussian random variables at the inputs of Doppler filters as well as the characteristics of

Ngày tải lên: 23/06/2014, 00:20

... coal-fired electricity generation comprisenearly 80 percent of the total CO2 emissions produced bythe generation of electricity in the United States, whilethe share of electricity generation from coal ... 1Carbon Dioxide Emissionsfrom the Generation of Electric Power in the United States Trang 2This report was prepared jointly by the staff of the U.S Department of Energy and the U.S Environmental Protection ... Department of Commerce, Bureau of the Census, Statistical Abstract of the United States, 1998 (Washington, DC, October 1998), Figure 1. Trang 108 Capacity factor is the ratio of the amount of electricity

Ngày tải lên: 29/06/2014, 02:20

... erythema limited to the foot or ankle, 2 = slight edema and erythema from the ankle to the tarsal bone, 3 = moderate edema and erythema from the ankle to the tarsal bone, and 4 = edema and erythema ... representative of three independent experiments. Trang 6in the culture supernatants of CD11c+ DCs of tolerized micethan in the supernatants of CD11c+ DCs of CIA mice cultured in the presence of CII (82 ... underlying the suppression by DCs of the expansion and dif-ferentiation of effector T cells and promotion of T-cell tolerance remain elusive One regulatory mechanism of DCs is the suppression of pro-liferation

Ngày tải lên: 09/08/2014, 10:22

... [6,7]). In these cases, the directionality of signaling is sufficient for developing mathematical models of how the patterns of activation and inhibition determine the state of activation of the network ... steps of the procedure The final values of the variables in the system are considered to be the stable steady states of the continuous model of the network Implementation The ... set to the default value of 1, and one parameter (the gain of the sigmoids) with a default value of 10. This set of default values sufficed to capture the correct qualitative behavior of the biological

Ngày tải lên: 13/08/2014, 23:20

... in its entirety To the best of my knowledge, I have duly referenced the sources of information and duly acknowledged the origin of other materials used in this thesis This thesis has not been ... on the way His excitement about the sometimes surprising results was infectious and his encouragement when I couldn’t see the light at the end of the tunnel helped me to enjoy the journey of ... and other angiogenic cells Ms Yingting Wang, a master student, who joined the project under my supervision during the last year helped with the conduction of some of the experiments Together

Ngày tải lên: 09/09/2015, 10:13

... contributed to the completion of this project To the rest of the friends in Paul A MacAry (PAM) laboratory, thank all of you, for the good laughs that never fail to pull me out of the brink of insanity ... attribute part of this thesis to her Life at work will not be as enjoyable and interesting without her around The continuation of all that we had set up together and the prospect of future discovery, ... co-supervisor, Professor Ng Mah Lee, Mary for offering so much advice and insight throughout my work on Dengue She, together with Mdm Boon had smoothen the path of my PhD journey by providing me with the

Ngày tải lên: 11/09/2015, 09:56

... infection Based on the shape of the monomer and the location of the antibody Trang 6epitopes, Rey et al postulated that the E protein has a „flat‟ topology along the surface of the virus lipid bilayer ... triggers dissociation of the prM/E heterodimers, which leads to the formation of 90 dimers that lie flat on the surface of the particle, with prM capping the fusion peptide of the E protein This ... across the globe have attempted to dissect the contributions by components of the adaptive immune system in DV immunopathology The hallmark of pathogenesis of DHF/DSS is the loss of endothelial

Ngày tải lên: 11/09/2015, 09:56

... examines the role of the family as a space of transmission and the function of gender as an idiom of remembrance The guardianship of the Holocaust is being passed on to us The second generation is the ... (the multiple hands holding the page and the photo, the expressionist drawing style that yanks the reader out of the commix style of the rest of the book, and the human forms that challenge the ... Children of the Holocaust (1979) to locate the beginnings of the current use of the notion of “memory” in the late 1980s and the 1990s: in contrast, they indicate, Epstein had described the “children

Ngày tải lên: 14/04/2016, 18:01

... improved the generation of the SME Wu and Jia (2016) analyze the issue from the perspective of the entry and exit behaviours of heterogeneous enterprises and find the development of the expansion of ... calculated as the ratio between the loan amount of four banks with the highest loan amount and the total loan amount of the banking market HHI is the sum of squares of the loan amount of each bank ... is the growth rate of the SME in the current period, it can indicate the overall development, generation and operation in a certain area and can directly reflect the trend of the number of the

Ngày tải lên: 01/02/2020, 22:22

... collecting procedures The aim of this study is to investigate the current social media presence of Aviano on their Facebook group “I Miss My Dad” in terms of contents and the influence of it to Aviano’s ... While the study analyzed the content of the Facebook page, it did not collect data on the total number of individuals who interacted with the page or the resulting sales generated This lack of quantitative ... likelihood of recommending Aviano's products based on their social media content on the "I Miss My Dad" Facebook group Out of the total number of respondents, only 2 customers rated their likelihood of

Ngày tải lên: 22/07/2024, 22:04

... enrich the pool of human capital not only for the auditing element of the profession, but for the more broadly defined accounting profession The significance of this issue is important for both the ... soon, there will be a growing shortage of qualified accounting professionals to meet the needs of the economy Past studies of the future of accounting education have also noted the importance of ... fundamental premise: The educational preparation of accountants should rest on a comprehensive and articulated vision of the role of accounting in the wider society This vision of the role of the well-accounting

Ngày tải lên: 18/02/2014, 01:20

... class share firms still trade) The main goal of the study is to examine the long-term impact of share unifications on the voting power of controlling shareholders and on the firm’s control structure ... attempt to undo the unification-induced dilution of their voting power In order to empirically address the issue of the possible post-unification “recovery” of the optimal level of control rights, ... present at the time of the unification Hence, in the short term (early post-unification years) controlling shareholders might have lost some of their voting power (due to the dilution effect of an

Ngày tải lên: 07/03/2014, 01:20

... b-protein is the b-site APP-cleaving enzyme 1 (BACE1) Here, we investigated the effects of genetic manipulation of BACE1 on the processing of the APP family of proteins BACE1 expression regulated the ... the total levels of soluble APP remaining constant irrespective of the presence or absence of BACE1 The levels of APPsa increased to account for the loss of APPsb (soluble C-terminally truncated ... together with associated proteins, are released from the membrane [49] Here we investigated the effects of genetic manipula-tion of BACE1 on the processing of APP, APLP1 and APLP2, and on the

Ngày tải lên: 15/03/2014, 10:20

... 143–56.] I THE DEFINITION OF THE SUPPLY OF MONEY The concept of the, supply of money plays a vitally important role, in differing ways, in both the Austrian and the Chicago schools of economics ... overriding attention The number of bathers at a beach may correlate more closely with the number of cars parked there than with either the temperature or the price of admission, yet the former correlation ... part of the money supply by virtue of their very existence; they continue as equivalent to money only so long as the subjective estimates of the sellers of goods on the market think that they

Ngày tải lên: 15/03/2014, 10:20

... glutton." And the whole science of æsthetics is, in the depth of it, expressed by one passage of Goethe's in the end of the second part of Faust;—the notable one that follows the song of the Lemures, ... one of the combinations of color, and the other of the combinations of line and form, which might each of them separately engage us in as intricate study as that of the science of music But of the ... description of Form, and expression of Thought 55 Now it is easy to show you the essential cause of the vast discrepancy in the character of these two buildings In the vault of the apse of the Duomo of

Ngày tải lên: 15/03/2014, 14:20

... relates to the effect of Stage Three of EMU on bank pricing First, the importance of the long-term market rate in the equilibrium price of retail bank products has often been reduced since the introduction ... 2001) The main lesson of these banking structure studies is that the pricing behaviour of banks may depend on the degree of competition and contestability in the different segments of the retail ... matching the one of these loans (deposits) We therefore propose to estimate, in the following sections, a model of bank pricing that provides accounts explicitly for the role of the term structure

Ngày tải lên: 15/03/2014, 14:20

... defining the value of an earning asset as composed of two components: the promised value, less the value of an option held by the bank (the lender) to take over the assets of the borrower if the loan ... Rf where EAk is the market value of the earning asset of repricing frequency k, BEAk is the promised value of the debt, Pt() is the put option on the assets of the firm, Ab, T is the time to repricing, ... in the short term would determine the magnitude of the effect of interest-rate changes and other shocks on bank profitability Our second objective is to use a large set of data, consisting of

Ngày tải lên: 15/03/2014, 14:20

... regulating the level of ammonium assimilation upon an ammonium pulse Analysis of regulation of the transient response of the GS rate The decrease in the rate of GS upon the sudden addition of ammonium ... explainedmechanistically in terms of the network topology and the kinetic properties of the molecular components of the network One possible approach to finding these explanations is through calculation of the properties ... (c) both thermodynamic and kinetic regulation Removal of thermodynamic regulation corresponds to neglecting the inhibitory effect of the backward reac-tion of GS on the rate of biosynthetic ammonium

Ngày tải lên: 23/03/2014, 13:20