the development of lung cancer

... the platinum-based drug resistant of lung cancer cells may involve in the regulation of let-7 and miR-29 to CSB Keywords: CSB, Let-7, miR-29, Platinum, Lung cancer Background Lung cancer is the ... therapy and the down-regulationof ERCC1-XPF by siRNA sensitizes lung cancer cells to cis-platin [9] CSB, the master sensor of TC-NER, is overexpressed in a variety of cancers including lung cancer ... and the re-expression of miR-29 in lung cancer cells can inhibit tumorigenesis [13] Due to the evidences that these miRNAs are involved in the lung cancer, it is im-portant to reveal the role of

Ngày tải lên: 17/06/2020, 18:33

... of Cur14–16 Therefore, the natural herbal Cur is less toxic than other chemotherapeutic agents in the treatment of cancer Despite of the safety and the broad pharmacological effects of Cur, the ... colorectal cancer is the world most common cancer and the third leading cause of cancer death in both male and female1,2 In spite of the development of novel powerful treatment, chemotherapy still plays ... colon cancer in the future. Cancer is one of the most severe diseases with increasing morbidity and mortality every year around the world According to statistics in the United States, colorectal cancer

Ngày tải lên: 01/11/2022, 09:55

... role in the development of oral cancer [28], esophageal cancer [29] and colorectal cancer [30] Furthermore the association between the presence of HPV 16 and the development of head and neck cancer ... neurogenesis The list of these genes is reported in additional file These results support the hypothesis of a possible role of E6 and E7 in the induction of neuroendocrine differentiation of SCLC ... Asian lung cancer is 35.7% The authors concluded that HPV may be the second leading cause of lung cancer after cigarette smoking Although studies of viral-related lung cancer have been reported, the

Ngày tải lên: 18/06/2014, 16:20

... be offered urgent referral to a member of the lung cancer MDT, usually the chest physician D 1.1.7 Patients should be offered an urgent referral to a member of the lung cancer MDT, usually the ... for men, who account for 60% of lung cancer cases In women, lung cancer is the second most common cause of cancer death after breast cancer Survival rates for lung cancer are very poor In England, ... incidentally suggestive of lung cancer, a second copy of the radiologist’s report should be sent to a designated member of the lung cancer MDT, usually the chest physician The MDT should have a

Ngày tải lên: 15/03/2014, 00:20

... effect of each of these exposures was attenuated in the presence of high levels of the other Conclusion Our findings provide further evidence that diesel exhaust exposure may cause lung cancer ... study of lung cancer nested in this cohort to evaluate the risk of lung cancer from exposure to diesel 2   Article | JNCI exhaust (The Diesel Exhaust in Miners Study [DEMS]) The purpose of the ... increased risk of dying from lung cancer Among heavily exposed workers, the risk of dying from lung cancer was approximately three times greater than that among workers in the lowest quartile of exposure

Ngày tải lên: 22/03/2014, 17:20

... pattern of development for genetic abnormalities in preneoplastic lung epithelium. Role of viruses in lung tumorigenesis The understanding of lung cancer molecular approaches has led to the development ... tumor development Tissue microarrays (TMAs) of lung cancerFigure 3 Tissue microarrays (TMAs) of lung cancer. TMAs are comprised of core biopsies of 0.6 mm in diameter of different tumors and of ... do not have the characteristics of cancer cells. Microdissection of lesions of the bronchial epithelium as well as of invasive tumors has provided purified tissue for the analysis of point mutations

Ngày tải lên: 12/08/2014, 18:21

... under the ROC curve (AUC) were pooled to evaluate the accuracy of miRNA-155 in the diagnosis of lung cancer For the prognosis analysis of miR-miRNA-155 in lung cancer, the pooled HRs and 95% CIs of ... with the pathogenesis of lung cancer, indicating that miR-155 acts as an oncogene in lung cancer [37,38] Zang et al revealed that miR-155 was involved in the drug resistance of lung cancer In their ... biomarkers for the diagnosis of lung cancer, so as to improve the diagnosis accuracy in the future By the way, as polymorphisms in genes encoding miR-NAs may alter the expression of the corresponding

Ngày tải lên: 17/06/2020, 19:12

... or in one of the 16 other certified breast cancer centers of the BRENDA-study group The primary end point of this trial was the risk of the development of bone-only metastases and the prognostic ... constitutes a site of para-mount importance for the development of distant metas-tases of breast cancer The establishment of metastases in the skeleton is based on mutual interactions of breast cancer cells ... classifying the grading of breast cancer, we applied the morphological assessment of the degree of differentiation of breast cancer described by Elston et al [22] Information on the time and site of first

Ngày tải lên: 21/09/2020, 01:22

... evalu-ate the significance of the above variants to the higher ex-pression of BDNF in lung cancer cells We found that the mRNA level of variants IV and VI was identical, only the mRNA level of variant ... to the proliferation and invasion of lung cancer cells Methods Lung cancer samples 110 cases of lung SCC and ADC samples were all from the Pathology Department in China Medical University The ... and the incidence and mortality of lung can-cer are increasing every year Lung SCC and ADC are the primary histological classification of lung cancer and included in this study The outcome of

Ngày tải lên: 21/09/2020, 02:07

... that, in the NC group 63.43 % of cells were in the G1 phase and 32.77 % of the cells were in S of the cell cycle, and in the BC group 63.02 % of cells were in the G1 phase and 33.87 % of the cells ... Organization (WHO) (2000) The pathological TNM status of all CRC was defined according to the criteria of the sixth edition of the TNM classification of the International Union Against Cancer (2002) In ... Colorectal cancer (CRC) is a common malignant disease and remains one of the leading causes of cancer mortality worldwide [1] With the development of China’s economy, the incidence of CRC in China

Ngày tải lên: 21/09/2020, 09:59

... non-small cell lung cancer (including adenocarcinoma, squamous, large cell lung cancer) and small cell lung cancer, **P < 0.01. Trang 6control cells (Figure 3C) To further verify the ability ofE2F1 ... For the peak value, the filtering was con-ducted according to the p value obtained by MACS analysis The data was discarded when the p value was higher than 1e-5, which ensured the fidelity of the ... early phase is the most important feature of SCLC In this study, we investigated the involvement of E2F1 in the process of invasion and metastasis in SCLC by regulating the expression of matrix metalloproteinases

Ngày tải lên: 05/11/2020, 00:08

... reviewthe literature to characterize the role of MET in the development oftumorigenesis, metastasis and chemoresistance, highlighting thepotential of MET as a therapeutic target in pancreatic cancer ... led to the recognition and development of targetedtherapies toward tyrosine kinase receptors such as the c-Metreceptor In this review, we characterize the role of c-Met in thedevelopment of tumorigenesis, ... we characterize the role of c-Met in the development oftumorigenesis, metastasis and chemoresistance, highlighting thepotential of c-Met as a therapeutic target in pancreatic cancer © 2014 Baishideng

Ngày tải lên: 20/10/2022, 09:01

... modification of the current ultrasound equipment The development of various types of probes for target diseases will be an issue in the future The target diseases could be: skin cancer, breast cancer ... the tumor side, was confirmed by the flow cytometry in our study Furthermore, the apoptosis induction of tumor cells and extension of survival time of cancer bearing mice were found even in the ... to several types of cancers, it is not yet considered as an established treatment On the other hand, due to the development of basic studies in recent years, the enhancement of drug effects by

Ngày tải lên: 02/11/2022, 09:25

... 1 h The participants were given an explanation regarding the purpose of the feedback, the purpose of the conceptual model, some background of the research that lead to the development of the ... By these definitions, and due to the importance of the role of project management in the success of projects, the authors consider related department collaboration on product development by the ... parts of a manufacturing company (2) Reduce new product development time by using the conceptual model (3) Reduce the cost of new product development by using this model The validation of the

Ngày tải lên: 07/03/2014, 00:20

... responibility is the continuing commitment by business to contribute to economic development while improving the quality of life of the Trang 189 workforce and their families as well as of the community ... aspect in Carroll’s concept mentions about other things rather than only the profit Trang 22of company, and carries out the promise of maximize the investment of shareholders In short, one company ... reliable Therefore, the company guarantees shareholders’ profit from their investment From these benefits, it can be said that there is a relationship between CSR and sustainability development of

Ngày tải lên: 13/03/2014, 14:20

... for sustained development The paper is divided into four major sections Section II briefly takes the bird’s eye view of the common characteristics of the general consensus about the development ... liberalization and particularly that of the capital account strongly contributes to the development of the financial sector in the long run (IMF,2000; Bailliu, 2000) 3.1 Movement of the Major Macroeconomic ... risky signal when the economic performance of other sectors goes down (as the consequences of crises), affecting the economic performance of the banking sectors Structural changes in the banking system

Ngày tải lên: 14/03/2014, 17:20

... molecules are the main triggers of the hyper-sensitive response (HR) in plants In the present study of the effect of ribo-flavin, which is excited to generate ROS in light, on the development of the HR ... Tokyo, Japan) On the basis of the absorbance value, the standard curve (obtained by adding the concentration gradient of H2O2) and the loaded weight of plant tissue, the content of H2O2was calculated ... in the 8 h group, and then the ratio rose dras-tically in the 12 h group, approximating to the level of ParA1 zones It is known that the fluorescence inten-sity of riboflavin provides a means of

Ngày tải lên: 15/03/2014, 00:20

... for the development of the breast, paradoxically oestrogen is also involved in the development of breast cancer via the stimulation and proliferation of breast cancer cells15,16 In fact, the ... breast cancer cases and for the remainder, scientists and doctors are still unsure of the causes2,3 One of the suggested additional risk factors for breast cancer is the environment, i.e the world ... development of the disease9, and 8 out of 9 women who develop breast cancer do not have an affected mother, sister, or daughter10 There are a small percentage of women who have faulty versions of genes

Ngày tải lên: 15/03/2014, 01:20

... methods of care reasonably directed to obtaining the same results The ultimate judgment regarding the propriety of any specific procedure must be made by the physician in light of all of the circumstances ... colorectal cancer because this may affect surgical decisions.9 The colorectal cancer risk in family members in-creases with the number of affected members, the closeness of the relationship to the patient, ... as-sessment of the size and degree of fixation of mid and low rectal tumors Although digital assessment of the extent of local disease may be imprecise, it provides a rough estimate of the local

Ngày tải lên: 15/03/2014, 01:20

... viên.  Theo dõi tình hình biến động lao động và tiền lương của cán bộ nhân viên.  Theo dõi và khiếu nại với cơ quan Nhà nước có thẩm quyền khi cơ quan BHXH vi phạm điều lệ BHXH.  Thực hiện và theo ... vào các ngày nghỉ theo quy định thì được thanh toán tiền lương theo đúng tỷ lệ của pháp luật lao động. Khi có công việc phát sinh mà Công ty đòi hỏi nhân viên làm việc thì tùy theo mức độ phức ... chính thức duyệt xét và đánh giá sự hoàn thành công tác của một cá nhân theo định kỳ. Người quản lý phải thường xuyên quan tâm theo dõi tình hình thực hiện công việc của người lao động. Qua đó người...

Ngày tải lên: 19/04/2013, 23:00