the critical perioperative period in cancer patients

... examine cognitive functioning and subjective cognitive complaints in cancer patients during treatment with the VEGFR TKI sunitinib or sora-fenib We found that these patients performed worse on the ... support the neces-sity for a longitudinal study on cognitive functioning in these patients We included both patients on sunitinib and sorafenib As both sunitinib and sorafenib inhibit the VEGFR2 ... testing Furthermore, the in vitro rodent data demonstrated that VEGF plays a role in cognitive functioning [7,8] The com-plaints of VEGF TKI treated patients about cognitive functioning and the...

Ngày tải lên: 05/11/2020, 00:55

... between the themes This informed the final theoretical synthesis of findings into overarching, analytical themes, or ‘core themes’ [47] These core themes were developed in rela-tion to the meta-synthesis’ ... for assessing the quality of included studies, and they were also used as a guide for reporting findings in this present meta-synthesis The strength of the COREQ guidelines lies in outlining three ... reassuring, strengthening, warming, Trang 9inviting, containing, peace-giving, and easing (seeAdditional file 2 Themes and illustrative quotes) Gardens provided consolation in the clinical setting and...

Ngày tải lên: 06/08/2020, 07:17

... a non-cancer re-lated reason of admission but had an ongoing active cancer as described in the patient history NCRH in-cluded patients where the diagnosis of cancer was men-tioned in the patients’ ... can-cer patients then all other patients For the endpoint of any cancer related therapy (ACDT and/or RT), cancer type and insurance type were Table 2 Descriptive statistics of clinical information ... symptoms in their final disease stages [35] Most of these differences were to be expected and are thought to be in accordance with the clinical practice for these cancers The observed de-crease in...

Ngày tải lên: 05/11/2020, 00:16

... resulted both in an increasing percentage of small breast cancers found at the initial diagnosis and in a small decline in mortality [2]. Howewer, as the current goal for breast cancer patients is ... surgery In this procedure, the skin flap covering the breast gland and the nipple-areola complex (NAC) are preserved In some cases the major ducts are removed. In the past, the nipple has been routinely ... approaches in breast cancer patients, there is no general agreement even on the definition of “negative” margins, and many describe such as the absence of tumor at the microscopic or inked margin, or...

Ngày tải lên: 09/08/2014, 03:21

... human cancer ● Rab31 and findings implicating Rab31 in human cancers ● Mechanisms underlying Rab31’s role in cancer – Why are Rab31 levels elevated in cancer cells? – Is Rab31 a driver in cancer, ... [77–79] In the next section, we outline how Rab31 has been implicated in human cancers, and in the section after postulate the underlying mechanisms based on recent findings Rab31 and findings implicating ... is highly expressed in the epithelial cells of the gastro-intestinal tract, lungs and kidney, has in the past few years been impli-cated in cancers from multiple organs These include breast [59,...

Ngày tải lên: 22/09/2015, 15:17

... broad aspects was drawn up, the researcher eliminated three of them within the writing process. After removing these three aspects from the list of factors to consider while evaluating success within the confines of the consumer processor industry, the following factors were left for the  ... In this release, the benchmark all the latest CPU’s using a variety of applications. The researcher has decided to incorporate two critical benchmarks into the literature review (See Appendix 2). These benchmarks relate to tasks (HDTV Playback and AVG Virus Scan) that average consumers might perform in their usage of their PC or Laptop. Looking at the HDTV playback benchmark  we can see that the difference in CPU utilization is minimal at the top end of the scale in terms  of  the  Intel  ... within  the  consumer  processor industry. That being said we can draw the following conclusions that due to the lack of FMA, Intel and AMD are forced to continuously innovate in order to maintain profit margins. ...

Ngày tải lên: 09/01/2020, 18:00

... broad aspects was drawn up, the researcher eliminated three of them within the writing process. After removing these three aspects from the list of factors to consider while evaluating success within the confines of the consumer processor industry, the following factors were left for the  ... In this release, the benchmark all the latest CPU’s using a variety of applications. The researcher has decided to incorporate two critical benchmarks into the literature review (See Appendix 2). These benchmarks relate to tasks (HDTV Playback and AVG Virus Scan) that average consumers might perform in their usage of their PC or Laptop. Looking at the HDTV playback benchmark  we can see that the difference in CPU utilization is minimal at the top end of the scale in terms  of  the  Intel  ... within  the  consumer  processor industry. That being said we can draw the following conclusions that due to the lack of FMA, Intel and AMD are forced to continuously innovate in order to maintain profit margins. ...

Ngày tải lên: 15/01/2020, 19:42

... education issues in developing countries in Asia and the main points in building policies for higher education and policy of importers in the international intergration period In Vietnam, the research ... benefit of the learners in the internation intergration period 11 Layout of the thesis Besides the introduction, conclusion and list of references, appendices, the main content of the thesis is ... member of the policy planning team? Do the managers involved in the building process of the objective of the policy? Do relevant parties involved/consulted in the policy building process ? Do the policy...

Ngày tải lên: 18/01/2020, 14:06

... broad aspects was drawn up, the researcher eliminated three of them within the writing process. After removing these three aspects from the list of factors to consider while evaluating success within the confines of the consumer processor industry, the following factors were left for the  ... In this release, the benchmark all the latest CPU’s using a variety of applications. The researcher has decided to incorporate two critical benchmarks into the literature review (See Appendix 2). These benchmarks relate to tasks (HDTV Playback and AVG Virus Scan) that average consumers might perform in their usage of their PC or Laptop. Looking at the HDTV playback benchmark  we can see that the difference in CPU utilization is minimal at the top end of the scale in terms  of  the  Intel  ... within  the  consumer  processor industry. That being said we can draw the following conclusions that due to the lack of FMA, Intel and AMD are forced to continuously innovate in order to maintain profit margins. ...

Ngày tải lên: 26/04/2020, 22:14

... receptor-interacting pro-tein kinase 1 (RIPK1)–receptor-interacting protein kinase 3 (RIPK3) –mixed lineage kinase domain-like protein (MLKL) [9] More specifically, RIPK1 kinase activity leads to the phosphorylation ... 153 patients and a minimum sample size of 54 patients (Mean 102.0) The accrual period of these studies ranged from 2013 to 2017 The regions represented in this study included the China (5) and the ... of cancer patients may be the result of decreased necroptosis signaling, leading to the resistance to death for cancer cells in these patients Fur-thermore, it has been proven that a growing...

Ngày tải lên: 03/07/2020, 01:14

... the first cancer such as radiotherapy and certain chemotherapy regimens [3–5] Since its introduction into clinical practice in 1970s, cis-platin, a chemotherapeutic agent binding to and causing ... Second cancers Second cancers were reported in 143 patients, includ-ing 75 patients in the cisplatin arm (raw event rate 1.91%) and 68 in the non-cisplatin arm (raw event rate 1.96%) The incidence ... 7403 patients Second cancers were reported in 143 patients, including 75 patients in the cisplatin arm and 68 in the non-cisplatin arm (raw event rates of 1.91 and 1.96%, respectively) The pooled...

Ngày tải lên: 23/07/2020, 23:48

... first examining the hematoxylin and eosin-stained prostatectomy tumor slides and then sampling tissue from the corresponding paraffin blocks A tissue microarray instrument (Beecher Instruments) ... profile of the IGF system in primary prostate cancer and its association with prognosis The expression of insulin-like growth factor-1 receptor (IGF-1R), insulin receptor (INSR), insulin-like growth ... or chemo-therapy prior to surgery), as previously reported [25] The clinico-pathological features of the PCa samples analyzed in the study, including the T2E status, are summarized in Table 1...

Ngày tải lên: 06/08/2020, 07:13

... at the beginning of the WMR program and takes a minimum of 30 min The session is aimed at 1) getting patients familiar with the program right from the beginning of their treatment, 2) initiating ... like to thank the Klinik Bavaria in Freyung, the Paracelsus-Klinik am See in Bad Gandersheim, the MediClin Rose Klinik Horn-Bad Meinberg, and the Röpersbergklinik in Ratzeburg for their support ... Due to the increasing survival rates of cancer patients, the specific role of RTW in coping with the disease, and the higher risk of being excluded from the labor market, a clear need for interventions...

Ngày tải lên: 20/09/2020, 15:00

... claim in the database after the VTE event We therefore explored patterns of long-term anticoagulant treatment in the remaining 415 patients Overall, long-term anticoagulant therapy was initiated in ... all cancer patients a 715 patients had portal vein thrombosis, 12 patients had hepatic vein thrombosis, 7 patients had thrombosis of renal vein. b 86 patients had portal vein thrombosis, 2 patients ... VTE, including pregnancy, major surgery, hospitalization, cancer treatments (chemo-therapy (including biologic (chemo-therapy), radiation (chemo-therapy, hormone therapy, and combination therapy),...

Ngày tải lên: 30/09/2020, 11:18

... scaled to have the same variance as that ob-served in the DLBCL GEP data The GEP data of the DLBCL and MM datasets were then merged together resulting in the HBCCL dataset In the development ... all cell lines without categorising them Fifth, combine the developed REGSs into a classifier and predictor for CHO Finally, sixth, validate the established REGSs in independent clinical cohorts. ... parameter, which shrinks the regression coefficients by penalising their size Increasing the amount of regularisation increases the shrinkage of each coefficient Here we used the elastic net penalty...

Ngày tải lên: 30/09/2020, 12:36

... to influence survival in cancer patients Furthermore, this study included non-terminally ill patients; this indicates that assessing these variables might also be useful in the non-terminal cancer ... obestatin, leptin and Ghrelin as biomarkers of cachexia ROC analyses were performed in order to define the diagnostic profile of obestatin, leptin and ghrelin in iden-tifying cachexia among cancer patients ... ex-penditure in patients with cancer cachexia There are severalin vitro data on obestatin involvement in the on-cologic field [21] Different studies have shown that obestatin has a role in regulating the...

Ngày tải lên: 30/09/2020, 14:56

... on the firms, including the decrease in expected future earnings and the increase in cost of capital (Hribar and Jenkins, 2004) We are interested to examine the role of financial analysts in ... conclude that the earnings uncertainty reflected in the forecast dispersion originates largely from noise in the financial reporting system rather than the fundamental uncertainty in the firm’s ... that the optimistic bias in FAF for the bankrupt firms declines to insignificant levels by the year prior to the bankruptcy filing They attribute the decline to the increasing costs for financial...

Ngày tải lên: 08/11/2015, 17:09

... each other, in many instances when one includes both physical functioning and performance status in the regression models, the likelihood of finding inconsistent results can be expected In other ... that pain and appetite loss are independent determinants of overall survival One found that a 40-point increase in the pain subscale of the EORTC QLQ-C30 was associated with a 27% increase in the ... between patients receiving intermittent and continuous treatment strategies The findings indicated that changes in the quality of life index, measured by a series of Linear Analog Self Assessment...

Ngày tải lên: 18/06/2014, 19:20

... LMWH in cancer patients (Table 1) [39-45] The Enoxaparin and Cancer (ENOXACAN) study compared the LMWH enoxaparin and UFH in 1,115 patients undergoing abdominal or pelvic cancer surgery Enoxaparin ... excluded from clinical trials, the patients included in clinical trials are typically in better health than cancer patients seen in clinical practice Conclusion Cancer patients are at increased risk ... unfractionated heparin *For definitions of major bleeding see original studies † Included non -cancer patients for routine thromboprophylaxis in medical cancer patients [1,16-19] However, in the Fundamental...

Ngày tải lên: 10/08/2014, 22:20

... life-sustaining therapy in ICU patients independently predict hospital death Intensive Care Med 2003, 29:1895-1901 Moreno R, Matos R: Outcome prediction in intensive care Solving the paradox Intensive ... discrimination with poor calibration This pattern has been observed in different settings and with different instruments [27] Information regarding the usefulness of these general scores in cancer patients ... patients requiring MV, 76% died in the hospital [33] In the present cohort about 37% of patients received MV Whether studying the entire population or the subgroup of nonscheduled surgical patients, ...

Ngày tải lên: 12/08/2014, 20:20