testicular cancer in childhood and non germ cell tumors

... tumour size and nodes were based on the International Union Against Cancer TNM staging system [12], and all of the patients were classified as having stage Ia, Ib and IIa lung cancer None of the ... conception and design, analysis and interpretation of data, involved in drafting the articles MG: substantial contribution to conception and design, statistical analysis and interpretation of data, involved ... need for non- invasive diagnostic procedures aimed at identifying lung cancer at an early stage and adding specificity to imaging techniques In 1999, Phillips et al [7] selected 22 VOCs – mainly alkanes...

Ngày tải lên: 12/08/2014, 18:21

... previously described [14]: = negative or faint staining in 10% of cancer cells; = moderate staining; = strong staining A score of was considered negative, ... receptor tyrosine kinases, which also includes HER2/neu, HER3, and HER4 [15] Activating mutations in the tyrosine kinase domain, involving mainly exons 19 and 21, play an important role in lung oncogenesis ... AF: Activating and resistance mutations of EGFR in non- small -cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors Oncogene 2009, 28(Suppl 1):S24-31 10 Molina-Vila MA,...

Ngày tải lên: 18/06/2014, 16:20

... thoracic radiotherapy in combination with mito- 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 mycin, vindesine, and cisplatin in unresectable stage III nonsmall -cell lung cancer J Clin Oncol 1999, 17:2692-2699 ... chemo-radiation in Head and Neck cancer [59,60] In conclusion: implementation of the treatment schedule used in EORTC study 08972/22973 in a non- randomised setting resulted in comparable outcome in our ... Worldwide and in Europe lung cancer is the most common cause of cancer related-death with an increasing incidence each year The majority of patients has Non- Small Cell Lung Cancer (NSCLC) and 75%...

Ngày tải lên: 09/08/2014, 10:21

... multiple stepwise linear regression analysis, suggesting a link between IMT, insulin resistance and dyslipidemia Insulin resistance is a common phenomenon and plays an important role in the cardio-cerebrovascular ... disease in obese population [17,18] In our study, the obese and MetS group both demonstrated increased fasting insulin than control group rather than fasting blood glucose Meanwhile, fasting insulin ... Short-term overeating induces insulin resistance in fat cells in lean human subjects Mol Med 2009; 15:228-34 Atabek ME, Pirgon O, Kivrak AS Evidence for association between insulin resistance and premature...

Ngày tải lên: 25/10/2012, 11:40

... formation, to a decrease in plasmin binding or to a combination of the two We demonstrate that both mAb 34D3 and mAb A10.2 inhibit plasmin binding to cells (Fig 5A) and fibrin (Fig 5B) in a concentration-dependent ... thus indicating accessibility and participation of both K1 and K4 in firmly anchoring plasmin to fibrin and cell surfaces Because the expanded Lys-form of plasminogen may be an intermediary in plasmin ... plasmin proteolytic activity on fibrinolysis and extracellular proteolysis, are lacking Furthermore, the relative importance of K1 and K4 in mediating interactions of plasminogen with fibrin and cells...

Ngày tải lên: 20/02/2014, 01:20

... Manufacturing Industries Three years Diploma in Engineering with 60% marks in aggregate from a recognised Indian University/Institute in the following respective branches Mechanical Engineering 04 ... examination, interview, selection and any other matter relating to recruitment will be final and binding on the candidate (22) The Candidates may please take note that the factory being a continuous ... examination, interview, selection and any other matter relating to recruitment will be final and binding on the candidate (22) The Candidates may please take note that the factory being a continuous...

Ngày tải lên: 09/03/2014, 00:20

... distribution in (a) Gainesville (ns200), (b) Miami (ns240), and non- urban areas (ns448) in Florida centrations in non- urban areas surrounding the two cities and land-use categories analyzed within the ... Edelman and de Bruin, 1986) suggesting that clay content is important in controlling the level and distribution of trace metal concentrations in soils A study conducted in both urban and non- urban ... between OC and arsenic concentrations in nonurban areas (Table 4) Humic substances in organic soils (peat) can serve as strong reducing and complexing agents and influence the processes controlling...

Ngày tải lên: 15/03/2014, 23:22

Ngày tải lên: 16/03/2014, 11:20

... effective in substantially reducing the risk of progression to cancer Conclusion Cost Effectiveness of Screening Much of the success in reducing the incidence of cervical cancer has come from expanded ... at: http://www .cancer. org The Body, an Internetbased HIV and AIDS information source, has a section on AIDSrelated cancers, including anal cancer, at: http://www.thebody com/treat/cancers.html ... cytological screening is reliable and effective In much the same way a Pap smear is used for identifying those at increased risk for cervical cancer, clinicians can use a swab to gather cells from the...

Ngày tải lên: 22/03/2014, 17:20

... COS-7 and SH-SY5Y cells generate different proNPFFA fragments indicating that a neuronal cell line possess a capacity of processing not found in non- neuronal cells The undecapeptide generated in ... N-terminal sequence of NPFF in mammals and recent reports demonstrating the importance of a protein convertase, the subtilisin/kexin isozyme SKI-1, in the processing of prohormones at specific nonbasic ... from extracts of non- neuronal COS-7 cells indicating that processing of hproNPFFA at a specific nonbasic residue should be considered to explain the presence of NPFF in cell extracts In contrast,...

Ngày tải lên: 31/03/2014, 07:20

... no staining (data not shown) Her2 staining was scored based on the scoring system applied to breast cancers, with scores of 0,+1, +2, +3 for increasing intensity and “continuity” of staining of ... (DakoCytomation, Carpinteria, CA) at 95°C, for 10 and 40 min, for Her3 and Her2 staining respectively To minimize non- specific staining, the section was incubated with protein block (DakoCytomation) ... including differentiation, migration, proliferation, and survival Her2 has an extracellular domain, but appears to lack ligand-binding activity, while Her3 has a non- functional kinase domain and...

Ngày tải lên: 18/06/2014, 22:20

... causing a threonine/isoleucine switch at amino acid location Thr399Ile (rs4986791) These polymorphisms alter the amino acid sequence of the TLR4 protein and affect the extracellular domain and ... (AB) The percentage of tumor cells showing a positive membranous/cytoplasmatic staining and the intensity of staining were assessed Cases with complete lack of staining were scored as negative, ... polymorphisms are linked with an increased susceptibility for gastric cancer and gallbladder cancer [15,16] In aggregate, these results delineate a clinically relevant pathway triggered by tumor cells with...

Ngày tải lên: 18/06/2014, 22:20

... assumption of a linear decline in Pmax is sometimes incorporated into leaf lifetime carbon gain models (Hiremath, 2000; Kikuzawa 1991) As it turns out, making an assumption of a linear decline in Pmax ... sucrose, or reoxidation in glycolysis and mitochondrial respiration The Calvin cycle, and starch and sucrose synthesis are anabolic processes requiring the input of energy- and reducingequivalents derived ... conductances and Pmax rates that were 30% and 13% lower, respectively, than the WT plants Aquaporin density as a factor in mesophyll conductance CO2 is complicated by its role in maintaining tissue...

Ngày tải lên: 19/06/2014, 12:20

... the intrinsic dissipation, we postulate an elastic domain defined by a convex function : ( , , )≤0 (79) The domain contains the origin, in other words: (0,0,0) < (80) Introducing the classic standard ... (108) Specialising to a linear isotropic porous material, after substituting (107) into (76) and taking into consideration the decomposition into the mean and deviatoric parts, and the initial stresses ... potential, definite positive, convex and contains the origin, can be defined: 79 Thermodynamics in Mono and Biphasic Continuum Mechanics ∗ = ∗( ) ; , ∗ = ; =− ∗ (47) so that the non- negativity...

Ngày tải lên: 19/06/2014, 12:20

... premelting and melting endotherms in Fig smoothly shifts to higher temperatures with stress increasing Multiple melting peaks in PET pellets (Kong & Hay, 2003) and filaments are observed and studied ... 0.12 MPa at a linear heating with the same heating rate (3.5 0C/min) and again in the temperature range from 20 0C to 200 0C The structural tests of the SHMM samples in this preliminary experiment ... 80 ml/min Temperature calibration was done using the onset melting temperatures of indium and zinc, and the energy calibration was based on the heat of fusion of indium Fibers were cut in pieces...

Ngày tải lên: 19/06/2014, 12:20

... interesting in that it works by supplying heat energy regardless of its origin (waste heat, geothermal water, solar energy ) Operating principle The operating principle of such a machine is briefly ... Duhem in 1899, relating to binary mixtures, that the absorption chillers have been growing significantly In 1930, Borzig had developed a machine using the couple water-ammonia This system is interesting ... Refrigerating System Operating at Low Enthalpy Sources Nahla Bouaziz, Ridha BenIffa, Ezzedine Nehdi and Lakdar Kairouani Engineering National School of Tunis Tunisia Introduction Since the work...

Ngày tải lên: 19/06/2014, 12:20

... landscape 152 Thermodynamics – Systems in Equilibrium and Non- Equilibrium 4.3 Main transformation modalities in the landscape In a landscape or in its subsystems (i.e Landscape Units) the main ... transforming itself following the time arrow, in a non- finalistic evolution and in a creative way That is why history has becoming indispensable Without it, it is simply impossible to understand properly ... Thermodynamics – Systems in Equilibrium and Non- Equilibrium (1928) maintain their significance as basic concepts in studying vegetation, but are in need to be integrated in new scientific theories...

Ngày tải lên: 19/06/2014, 12:20

... (lines are eye-guides), and b) corresponding H/T versus 1/T plot (lines are linear fits to isomagnetic points) 182 Thermodynamics – Systems in Equilibrium and Non- Equilibrium Will-be-set-by -IN- TECH ... construct the scaling plot, using the obtained λ1 and λ3 parameters (Fig 8(b)) From the scaling plot and the subsequent fit with the Brillouin function, we obtain values of spin and saturation magnetization ... from the non- equilibrium thermodynamics, concerning living systems and, consequently, (b) to revise the main concepts of vegetation science in the light of the new “Landscape Bionomics” and indicate...

Ngày tải lên: 19/06/2014, 12:20

... and   Q are respectively the Prandtl number and the heat/sink k k parameter Introducing the variable  Pr 2 e  (17) And inserting (17) in (15) we obtain      Pr  Pr    1 ... isotherms from Landau theory, for a first-order transition, with equilibrium (solid lines) and non- equilibrium (dashed and dotted lines), and b) estimated ΔS M versus T for equilibrium and non- equilibrium ... Generation in Viscoelastic Fluid Over a Stretching Surface Saouli Salah and Aïboud Soraya University Kasdi Merbah, Ouargla, Algeria Introduction Due to the increasing importance in processing industries...

Ngày tải lên: 19/06/2014, 12:20

... fields in pure and applied sciences, because they can be used as models for several biochemical and pharmacological systems and can solubilize water-insoluble substances (including certain medicines/drugs) ... effect on the cmc and their thermodynamics of amphiphilic drugs Clouding is a well-known phenomenon observed in non- ionic surfactants The clouding phenomenon can be induced by changing the temperature ... determine the cmc of these drugs in presence of different additives The surface 232 Thermodynamics – Systems in Equilibrium and Non- Equilibrium properties (in water and in presence of varying mole...

Ngày tải lên: 19/06/2014, 12:20