stigma in facially disfigured cancer patients

... comprise patients with traumatic brain injury, periopera-tive brain mass lesion, acute intracranial bleeding, spinal cord injury, spinal lesions and tumors, subarachnoid hemorrhages, and, increasingly, ... prostaglandin E1 (PGE1) are used to suppress inflammatory cytokines such as interleukin 6 and interleukin 8 Several studies have indicated that the use of corticosteroids in the pre- and intraoperative ... applied with insulin infusion and those with excessive vomiting Hyperkalemia may be seen in patients with cronic renal failure and acidemia Hypocalcemia is an anticipated finding in cases of liver

Ngày tải lên: 20/01/2020, 10:55

... Procedures in Critically Ill Cancer Patients 1 Epidemiology of Mechanical Ventilation and Acute Respiratory Failure in Cancer Patients 3 Dulce Apolinário 2 Breathlessness in Advanced Cancer Patients: ... Therapeutic Procedures in Critically Ill Cancer Patients Trang 12© Springer International Publishing AG 2018 A.M Esquinas et al (eds.), Mechanical Ventilation in Critically Ill Cancer Patients, https://doi.org/10.1007/978-3-319-49256-8_1 ... and Acute Respiratory Failure in Cancer Patients Trang 17© Springer International Publishing AG 2018 A.M Esquinas et al (eds.), Mechanical Ventilation in Critically Ill Cancer Patients, https://doi.org/10.1007/978-3-319-49256-8_2

Ngày tải lên: 23/01/2020, 17:40

... relatively slowly In some patients, the SCC-Ag level began to increase within 1 month after surgery In other patients, the SCC-Ag level reverted and increases during Table 1 Clinicopathological ... Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 2018;68(6):394 –424. 2 Cohen PA, Jhingran A, Oaknin A, Denny ... and Bin Kang contributed equally to this work. 3 Fudan University Shanghai Cancer Center – Institute Merieux Laboratory, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China

Ngày tải lên: 17/06/2020, 03:14

... of Parkin may promote cancer however the precise mechanism ofParkin inactiva-tion remains unexplored mainly in breast cancer Aberrant promoter methylation is a widespread mech-anism in cancer ... ofParkin mutations in breast cancer were obtained Oncomine database and UALCAN analysis Oncomine database was exploited to investigate the mRNA expression of Parkin in breast cancer using the criteria ... with clinical parameters of the patients, we Fig 4 Oncomine analysis showing loss of Parkin (PARK-2) expression in different types of breast carcinoma in TCGA a Invasive lobular breast carcinoma

Ngày tải lên: 17/06/2020, 17:24

... Nordgard O Disseminated tumor cells in bone marrow assessed by TWIST1, cytokeratin 19, and Mammaglobin a mRNA predict clinical outcome in operable breast Cancer patients Clin Breast Cancer. 2010;10(5):378 ... in bold Trang 8breast cancer patients is still not clearly defined, evi-dence indicates that BM is a common homing target for tumor cells in many types of carcinoma before they re-circulate into ... study involves the longest follow-up reported in breast cancer studies investigating the clinical signifi-cance of DTC detection Methods Patient cohort The patients (n = 191) included in this

Ngày tải lên: 17/06/2020, 19:02

... a standard staining protocol on the Labvision system (Thermo Fisher Scien-tific Inc., Waltham, USA) For both stainings, the pro-portion of invasive tumor cells with nuclear staining was assessed ... staining, one of the TMAs was quantified independently in a blinded manner by a second observer (JS) to calculate inter-observer variability The inter-observer variability was analyzed using ... cell cycle inhibitors have been shown to be benefi-cial in metastatic breast cancer patients when added to endocrine therapy, both in CCND1 amplified tumors as well as in unselected patients [34]

Ngày tải lên: 03/07/2020, 00:49

... different at baseline (in the direction of increased aging) in CG compared to CTG, corresponding to the fact that clinical aging was also slightly more pronounced in Association of aging miRNAs with ... biological aging, by analysing the behaviour of circulating aging-related miRNAs Indeed, in addition to the above-mentioned aging bio-markers, several miRNAs have also been implicated in non-coding RNAs, ... stating that adjuvant TC chemotherapy does not significantly boost aging progression in elderly breast cancer patients Our findings also endorsed specific age-related miRNAs as promising aging/frailty

Ngày tải lên: 03/07/2020, 00:52

... staining was specific The staining intensity in the nuclear and staining per-centage of tumor cells were both evaluated: no staining was given a score 0; a faint, moderate or strong staining ... expression In order to further validate this finding in protein level, we analyzed RECQL protein expression in an independent cohort (N = 322) In the second cohort, patients with low protein level ... all data in the study Fig 1 Immunohistochemical staining for RECQL expression in breast cancers RECQL showed a negative staining and b positive staining (magnification × 200) Trang 5Clinicopathologic

Ngày tải lên: 24/07/2020, 01:40

... methylation with protein expression in Indian breast cancer patients YAP1 protein expression YAP Promoter Methylated (% within Protein expression) Unmethylated (% within Protein expression) Total ... spor-adic breast cancer cases were included in the study Nor-mal adjacent breast tissue not infiltrated with tumor served as control Inclusion criteria included female breast cancer patients in the age ... 50.0, Obs/Exp > 0.60 Trang 5min 3, 3’ – diaminobenzidine (DAB) was then added tovisualize the antibody binding site followed by counter-staining with hematoxylin Normal breast tissue served

Ngày tải lên: 24/07/2020, 01:52

... preserving strategies in cancer patients derive mainly from small single center retrospective or pro-spective series At the time of cancer diagnosis, approximately 50% of young breast cancer patients ... barriers remain in discuss-ing and dealdiscuss-ing with these issues The PREFER study represents a comprehensive program in young breast cancer patients across several Italian institutions aiming to ... and are inter-ested in maintaining fertility and future reproductive capacity [7] International guidelines recommend an early and prompt discussion about the possible risk of developing these

Ngày tải lên: 06/08/2020, 07:09

... Colorectal cancer Background Colorectal cancer (CRC) is the second most common cancer in females and the third most common cancer in males worldwide [1] It is one of the most rapidly growing cancers in ... is lower than in western patients.important in predicting the prognosis of early CRCs, which is one of the novel findings of our study Our findings support a role forBRAF mutation in the natural ... and OS according to KRAS mutation status in combination with BRAF a DFS according to KRAS mutation status in combination with BRAF and b OS according to KRAS mutation status in combination with

Ngày tải lên: 06/08/2020, 07:22

... remains, however, unclear in this population Considering the recent interest in phenotypic changes and tumor heterogeneity during breast cancer progression, additional tumor markers could be interesting ... ECD in HER2-negative tumors as well [19] Other biomarkers have been investigated to predict outcome in MBC patients, including circulating tumor cells and growth factors [14, 18] Considering ... Considering the recent interest in phenotypic changes and tumor heterogeneity during breast cancer progression, it could be interesting to evaluate additional tumor markers in this setting to better assess

Ngày tải lên: 21/09/2020, 01:45

... concurrent malignancy other than non-melanoma skin cancer, or in situ cervix carcinoma Trang 3Baseline evaluation included a physical examination(including evaluation of vital signs and performance ... fingerprinting in November 2013 (Power Plex 1.2, Promega, Madison, WI, USA) as tumor model target cells, and patients’ PBMCs as effectors The cell line was cultured in DMEM (Sigma), containing ... setting [22] The impressive results obtained without anthracyclines, at least in a selected population of patients, may become“practice-changing” in the next few years Achievement of pCR in patients

Ngày tải lên: 30/09/2020, 13:20

... an independent prognostic factor for Chinese patients Our finding that KRAS codon 13 mutations (in particular G13D) are associated with inferior survival in BRAF wild-type CRCs in Chinese patients ... patients Conclusion: Our findings indicate that PI3K/RAS-RAF signaling pathway genes are frequently mutated in Chinese CRC patients, but have different characteristics than found in Western patients ... extra 9 patients were excluded from the remaining 223 patients because of poor DNA quality At last 214 patients were included in our study (Figure 1) There was no difference in the major clinicopathological

Ngày tải lên: 30/09/2020, 14:46

... baseline labora-tory parameters such as haemoglobin, bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and creatinine Although timing and reasoning of GCSF use were incomplete, ... occurrence in patients receiving chemotherapy with epirubicin A predictive role for WBC or ANC in CIN and FN occurrence in cancer patients receiving chemotherapy has been described in other studies ... factors predicted FN in breast cancer patients Prediction was improved by adding genetic information but overall remained limited Internal validity was satisfactory Further independent validation

Ngày tải lên: 05/11/2020, 00:50

... Denaro V, Tonini G: Pamidronate induces modifications of circulating angiogenetic factors in cancer patients Clin Canc Res Off J Am Assoc Can Res 2002, 8(5):1080 –1084. 9 Santini D, Vincenzi B, ... type Invasive ductal and lobular Grading T staging N staging M staging Trang 6out of 81 patients (45.7%; 95% CI, 34.6 to 57.1) in theLET + ZOL arm (P = 0.192) Effect on surgery A total of 12 patients ... the patients who participated in this study We would also like thank the investigators and their institutions for treating the patients in accordance with the study protocol and for reporting

Ngày tải lên: 05/11/2020, 01:05

... 2Gastric cancer remains a significant health problem des-pite its declining incidence in the West It is the fourth most common cancer worldwide, accounting for 8.6% of all new cancer diagnoses in 2002 ... and PLR in advanced gastric cancer patients receiving first-line palliative chemother-apy in terms of providing useful information regarding prognostication This study also reports the investigation ... outcome in advanced gastric cancer patients with an initial abnormal NLR and in assisting clinical decision-making Platelet count is an additional index of systemic in-flammation elicited by the

Ngày tải lên: 05/11/2020, 05:50

... staining and evaluate the predictive significance on survival in 32 CTCs-positive patients with advanced CRC Results: Forty-eight of 98 patients were CTCs-positive, including 18 CTM-positive patients, ... CTCs-negative patients, which indicated that patients with high CEA levels had more opportunities to be CTCs-positive Moreover, CTC count was increasing with decreasing tumor de-differentiation, increasing ... manuscript did not include details, images, or videos relating to individual participants. Consent to participate Informed consent was obtained from all individual participants included in the study.

Ngày tải lên: 19/11/2022, 11:47

... care in such women To this end, we performed a systematic review of HRQL research targeting breast cancer patients in Spain, analysing the studies published and instruments used, and summarizing ... “Spain” in PubMed, EMBASE and PsycINFO, with “Breast Cancer also being used as a key word; “Quality of life” AND “Breast cancer in Dialnet; “quality” AND “life” AND cancer AND “breast” in ... relative interest in HRQL research in breast cancer patients within a more international context The systematic search and review processes were conducted in accordance with PRISMA (Preferred Reporting...

Ngày tải lên: 20/06/2014, 15:20

... cloning these into the pCR4-TOPO vector (Invitrogen) For each PCR, positive control plasmids containing the R- or Q-sequence were included Recombinant Proteins, Immunization Recombinant proteins ... protein was subsequently tested by immunofluorescence assay using HEK 293T cells expressing XMRV and cells expressing the gp70- or pr65 proteins alone No XMRV specific binding was seen, indicating ... found using RNA-based microarray techniques in tissue samples from prostate cancer patients [10] XMRV was detected predominantly in patients who are homozygous for the QQ allele at R462Q in the...

Ngày tải lên: 12/08/2014, 23:22