... IL-13) These mediators can profoundly affect the permeability of the vascular endothelium, allowing the migration of circulating immune cells to migrate through the endothelium into the site of inflammation ... AHR in some asthma models (116, 117) The heterogeneity of findings with regards to the role of Th1 T cells in Trang 38dependent on the nature of the disease or the nature of the allergens involved ... 1.1 Overview of the immune responses involved in allergic asthma The protease activity of the allergen allows the allergen to penetrate through the epithelium Activation of PRRs on the dendritic
Ngày tải lên: 15/09/2015, 21:56
... measurement of the data in term of its distribution.The value of the score is high if the two means of the classes are very different andthe data of each class are crowded near the mean of the data ... INTO THE USE OF GAUSSIANPROCESSES FOR THE ANALYSIS OF MICROARRAY DATASIAH KENG BOON NATIONAL UNIVERSITY OF SINGAPORE 2004 Trang 2AN INVESTIGATION INTO THE USE OF GAUSSIANPROCESSES FOR THE ANALYSIS ... of the gradient information ofthe particular distribution In Gaussian Processes, the gradient of the evidencefor hyper-parameter (Θ) can be found as shown in (3.41) Thus, if the gradient of the
Ngày tải lên: 28/09/2015, 13:38
Capillary and microchip electrophoresis for the analysis of small biomolecules
... applied, the mobile layer of buffer cations migrates towards the cathode As it does, it drags the bulk of the buffer solution along with it and thereby generating the EOF The strength of this EOF is ... this will raise the buffer’s viscosity and thereby lowering the strength of the EOF The EOF, thus, determines the times at which the charged compounds migrate out When a strong EOF is generated ... commonly utilized for the microfabrication of such microchips35 The design of the fluid circuit is first printed on a transparency or chrome mask The smallest feature size of the former is limited
Ngày tải lên: 02/10/2015, 12:56
Finite element model for nonlinear analysis of steel–concrete composite beams using Timoshenkos beam theory
... to obtain the weak form of the balance condition of the problem: ∂ ∑ ∫ ∫ b d ∑ ∫ t d where b and t are the body and surface force respectively; (α =c s, ) From Eq (9) in weak form, the stress ... introduced a beam model including the shear deformability of the steel component only This model was obtained by coupling an Euler–Bernoulli beam for the RC slab with a Timoshenko beam for the steel ... located ms for both s of CB mo o the analyti of material ent-based fin d two two-sp nd Zona 200 of axis X, Y, and by the st provided by whose dom mptions for by vector d are the ax d at y and the
Ngày tải lên: 03/06/2016, 19:11
A model for the prediction of subgrade soil resilient modulus for flexible pavement design
... fulfillment of the requirements for The Master of Science Degree in Civil Engineering The University of Toledo December 2004 Subgrade soil plays a very important role in the construction of roadways Before ... “Education is not the taming or domestication of the soul's raw passions not suppressing them or excising them, which would deprive the soul of its energy but forming and informing them as art.” ... use of asphalt and the popularity of the automobile triggered the dawn of design methods The aim of these design methods is geared towards better performance and longevity of pavement so that
Ngày tải lên: 04/07/2016, 17:20
QuEChERS A Mini-Multiresidue Method for the Analysis of Pesticide Residues in Low-Fat Products
... lost The extent of losses de-pends on the amount of lipids in the sample as well as on the polarity of the analytes with the most non-polar ones showing the highest losses In the presence of ... However, these compounds are stable at the pH of the non-acidified extract (after dispersive SPE) over several days If these compounds are within the scope of analysis an aliquot of the non-acidified ... employ the internal standard at the end of the procedure (to an aliquot of the final extract) assuming the vol-ume of the organic phase as being exactly 10 mL It should be furthermore noted that the
Ngày tải lên: 06/10/2016, 09:38
Birkhäuser boston daniel h greene donald e knuth mathematics for the analysis of algorithms
... science at Stanford University on the analysis of algorithms The course presents examples of the major paradigms used in the precise analysis of algorithms, emphasizing some of the more difficult ... directly into the analysis of an algorithm The study of radix exchange sort, for example, uses the sim- ple set of relations (1.22) introduced at the beginning of this section For details see ... build up a table that shows the values of f(n) for small n, together with a list of the values of k where the maximum is achieved: In some iterations the location of the max has many possibilities,
Ngày tải lên: 18/04/2017, 12:21
Freeze-drying: An alternative method for the analysis of volatile organic compounds in the headspace of urine samples using solid phase micro-extraction coupled to gas chromatography - mass
... know that the migration of compounds from the urine, or liquid phase, to the headspace of the vial, or gas phase, depends on the volume of the liquid phase, the volume of the gas phase and the affinity ... freeze-dried, with the addition of 1 ml of saturated NaCl solution (salt), with the addition of 1 ml of 5M HCl solution (acid) or with the addition of 1 ml of 5M NaOH solution (base) The results obtained ... in the liquid phase, which results in more compounds moving to the gas phase It is known that the addition of acid reduces the pH of the solution and increases the volatility of acids, while the
Ngày tải lên: 29/05/2020, 13:33
mathematics for the analysis of algorithms (3rd ed ) greene knuth 2007 11 05 Cấu trúc dữ liệu và giải thuật
... science at Stanford University on the analysis of algorithms The course presents examples of the major paradigms used in the precise analysis of algorithms, emphasizing some of the more difficult ... directly into the analysis of an algorithm The study of radix exchange sort, for example, uses the sim- ple set of relations (1.22) introduced at the beginning of this section For details see ... build up a table that shows the values of f(n) for small n, together with a list of the values of k where the maximum is achieved: In some iterations the location of the max has many possibilities,
Ngày tải lên: 29/08/2020, 18:31
Evaluation of TgH(CX3CR1-EGFP) mice implanted with mCherry-GL261 cells as an in vivo model for morphometrical analysis of glioma-microglia interaction
... and then the needle was pushed back 0.5 mm to inject the rest of the volume About 5 min were spent to complete the injection and two Trang 3additional min for totally removing of the needle Thesub-cutaneous ... mixture of O2 (50%), and N2O (50%) at 120 strokes/min (100–160 μl/stroke depending on the body weight) A lon-gitudinal incision of the skin was performed between the occiput and the forehead The ... quantitative cell analysis during their infiltration into the tumor mass The present GL261/CX3CR1 glioma model also allowed imaging of microglial cells present in tumor areas for analysis of morphology
Ngày tải lên: 21/09/2020, 11:32
A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays
... correlated with the FIRMA scores for an alternatively spliced exon as both the random effects of the REIDS model will resist and the residuals of the FIRMA model will be large The combina-tion of an exon ... based on informaalterna-tive calls The concept of informative or non-informative calls was intro-duced for arrays by applying a factor analysis model to calculate a score of informativeness based ... panel: the probe set 2319718 of the KIF1B gene Right panel: the probe set 2751068 of the PALLD gene The black and blue lines indicatethe mean profiles of the gene and exon level data respectively The
Ngày tải lên: 25/11/2020, 17:48
Mathematics for the analysis of algorithms
... đầu tiên) cần được sắp xếp theo thứ tự (tăng) Trước hết ta so sánh hai số đầu tiên, nếu chúng không theo thứ tự thì ta đổi chỗ cho nhau để được thứ tự mong muốn Tiếp theo ta so sánh số thứ hai ... tiếp theo chiều ngược lại kể từ vị trí ngay trước khi kết thúc lượt đó Chẳng hạn sau khi kết thúc lượt đầu, ta so sánh hai số ở vị trí thứ (n − 2) và thứ Trang 6(n − 1) với nhau; tiếp theo đó, ... thức tường minh cho 𝑥𝑛 nếu x 1 =1 Lời giải Xét một hoán vị a1a2 · · · a n of [n], và ta sẽ chia thành 2 trường hợp, tùy theo giá trị của a1 Nếu a1 = 1 thì a1a2 · · · a n được xếp xong sau 2 lượt
Ngày tải lên: 13/01/2021, 21:14
A simple displacement model for response analysis of EPS geofoam seismic buffers
... through the backfill soil from the heel of the buffer at a to the horizontal The system of forces acting on the block is shown in Fig 2 Here, m is the mass of the soil block and u¨gand g are the corresponding ... of the normal spring constants at the soil wedge boundaries are calculated based on assumed values for the modulus of elasticity of the materials and the depth of the zone in the direction of ... elevations above the base of the wall were connected to metal plates embedded in the surface of the geofoam layer to record lateral displacements (compres-sion) of the geofoam Details of the experimental
Ngày tải lên: 18/05/2021, 17:26
Some statistical methods for the analysis of survival data
... Statistical Methods for the Analysis of Survival Datain Cancer Clinical Trials Thesis submitted in accordance with the requirements of the University of Liverpool for the degree of Doctor in Philosophy ... Computational methods of the analysis of propor-tional hazards models In this section, exploration is given to the formulation of likelihoods for various forms of proportional hazards models Introducing ... estimates Further, notethat the exponential model can be expressed as a special case of the Weibull model with fl = 1 To illustrate the uses of parametric models the likelihoods of the Weibull,
Ngày tải lên: 03/09/2021, 22:51
Model for the electrolysis of water and its use for optimization
... clear, therefore, that a better model than the classical model is needed for gas production in electrolysis Thus, the new model is based on the premise that each electron will break a bond This model ... This model is based on the electron number instead of the energy It can be thought of as a transportation model instead of a continuous model Using this model we can calculate the theoretical hydrogen ... production Based on this new theoretical model for hydrogen production and the experimental results, the efficiency of electrolysis in creating hydrogen gas can be calculated by taking the ratio of the
Ngày tải lên: 28/10/2022, 05:18
a pspice model for the study of thermal effects in capacitive mems accelerometers
... in opposite direction of the acceleration, due to Newton’s law of motion The force by the acceleration is F Ma Where M is the mass, a is the acceleration. The dynamics of a simple accelerometer ... temperature, ε is the Strain,T σ is theT stress, E is the Young’s Modulus of silicon material Moment of inertia of a beam is given by I bh3 12.Where b is the width of the cantilever beam and h is the thickness ... source; (b) VCVS for thermal expansion coefficient and young’s modulus. Temperature is varied in the range of 100K to 400K for the device and the performance is studied The thermal expansion
Ngày tải lên: 01/11/2022, 08:54
fractal geometry based hypergeometric time series solution to the hereditary thermal creep model for the contact of rough surfaces using the kelvin voigt medium
... one of the main tools for studying statistical models of rough surfaces The autocorrelation function Rδ of the profile is Trang 7Another tool for the characterization of surfaces is the spectral ... technique44 is then used to derive thethermoviscoelastic model from the corresponding elastic model The main contribution of Trang 10this work is a mathematical model for the time-dependent-creep of a ... theapproach of punch surface and half space is in the order of the size of the surface roughness Theclosed-form results are obtained for selected values of the system parameters; the fractal
Ngày tải lên: 02/11/2022, 10:41
Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx
... validity of the new model for the analysis of the mechanisms of cartilage destruction by SFB Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible for the cleavage of other extracellular ... established the modified, present form of the model, performed the real-time PCR, the immunohistochemistry and the respective data analyses and wrote the manuscript D Pohlers performed some of the experiments ... basis of their known caseinolytic activity and the molecular weight of their latent and active forms were then identified by western blot analysis of the same pooled supernatants Western Blot for...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy" pptx
... providing the base for the development of individual and more efficient anticancer treatment regimens However, most experimental data are based on either animal models, the extrapolation of which ... treatment for patients with NSCLC The complete analysis of the part infiltrating cells might play within the tumor scenario, which would have exceed the extent of this study, is a necessary theme of ... responsible for the surgical part of the investigation CM and ARR carried out the LIFE/DEAD-assay and 2-photon microscopy PZ was involved in the design of the study, evaluation of the results...
Ngày tải lên: 12/08/2014, 15:20
Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc
... structure of C24 Doc S1b sbml format of model structure of C24 Doc S2a Model structure of Rsch Doc S2b sbml format of model structure of Rsch Doc S3 Documentation of the model structure This supplementary ... assessment of the trajectory of interconversion rates as a function of time of cold exposure, (b) comparison of the magnitudes of the various interconversion rates, and (c) lineup of the accessions ... also depends on the concentration of the reaction product and the dissociation constant Ki,B for inhibitor binding The rate of hexose-based sucrose synthesis was described by the mass action...
Ngày tải lên: 14/02/2014, 22:20