solidstate nuclear magnetic resonance spectroscopy theory and pharmaceutical applications

... NOE stands for Nuclear Overhauser Effect Probably only physicists stand the NOE fully, and we shall not go into the theory but only present the results It is a phenomenon which is useful and important ... NMR, infrared spectroscopy (IR), ultraviolet spectroscopy (UV) and mass spectrometry (MS) However, the information available from UV and MS is limited in its predictive capabil-ity, and IR is useful ... doublet) at 1.33 ppm, the distances between lines 1 and 3, 2 and 4, 3 and 5 or 4 and 6 are equal to (3JH-C-C-H): we irradiate the methylene protons and observe the methyl protons The result of this

Ngày tải lên: 31/05/2017, 09:04

... height and area • NAA/Cr height and area • Cho/Cr height and area • mIns/NAA height and area • mIns/Cho height and area • mIns/Cr height and area • NAA/Cho height and area • NAA/Cr height and area ... height and area • mIns/NAA height and area • mIns/Cho height and area • mIns/Cr height and area • NAA/Cho height and area • NAA/Cr height and area • Cho/Cr height and area • Lac/NAA height and area ... H-MRS: Proton magnetic resonance spectroscopy; Lac: Lactate; lip: Lipid; LV: Low voltage; MDI: Mental Developmental Index; mIns: myo-inositol; MR: Magnetic resonance; MRI: Magnetic resonance imaging;

Ngày tải lên: 01/02/2020, 21:26

... children include sonography, hepatobiliary scin-tigraphy, CT and magnetic resonance cholan-giopancreatography (MRCP) Imaging of the pancreas and biliary system often requires a combi-nation of two ... the biliary system This article reviews MRCP techniques and their applications for assessing anatomic biliary and pancreatic variants and common pediatric diseases TECHNIQUE Conventional Techniques ... pressure and distension of the biliary and pancreatic ducts Silva and Friese18 have described the use of morphine during MRCP in adults to improve the visualization of small intrahe-patic biliary and

Ngày tải lên: 29/12/2020, 19:34

... 10 and 5% D 2O and 5 mM ammonium acetate, are shown in Figures S1a and S1b along with their proton STD responses These three formamides are neutral under the test conditions and have similar and ... separations [25] Nuclear magnetic resonance (NMR) has for decades been used for characterizing stationary phase chemistry [ 26, 27], as a spectro- scopic detection technique in HPLC [28], and more recently ... due to the polar ligands of the HILIC phases, and also to widen the un- derstanding of the interactions that govern retention in HILIC 2.1 Chemicals Ammonium acetate ( ≥98 %) and formic acid were

Ngày tải lên: 25/12/2022, 00:54

... habitat and natural landscape linkages Public lands presently provide most cougar habitat, and management of these lands should consider the needs of cougar populations — prey cover, security, and ... environment, such as the loss of forests and grasslands and their valuable animal and plant products, or impairment of water supplies essential to human life and agriculture Further-more large cats, ... techniques, and methods of live-stock husbandry Studies of cougar population dynamics could help managers develop population objectives, assess impacts of harvest and control, and provide an understanding

Ngày tải lên: 12/08/2014, 02:20

... trophy males is expanding and generating new ecological, social, and economic challenges and opportunities (Hofer 2002) “Alternative” hunting products such as penned hunts and hunts for exotic ... of wolves and cougars to protect endangered Vancouver Island marmots (Marmota vancouverensis), even though both predators are plentiful (on Vancouver Island and in many other areas) and the marmot ... endangered species legislations and requirements to consult with Aboriginal Peoples and various stakeholder groups These changes require new ideas and initiatives from wildlife and social scientists Ungulate

Ngày tải lên: 12/08/2014, 02:20

... by Kie and White (1985) Fawn survival from birth to fall is erratic (Ginnett and Young 2000) and low compared to white-tailed deer populations in general (Downing and Guynn 1985) Unhunted and otherwise ... (March, April, and May) rainfall total (cm) for time t, and Z t is standard noise (with Z1, Z2, uncorrelated) Unknown parameters to be estimated from the data were a, b, c, and σ The random variables ... 1964 and 1969) and V t = mean embryos/adult doe, whereas N t= number of deer The second method used to test for density dependence was described by Dennis and Otten (2000) Because Ginnett and

Ngày tải lên: 12/08/2014, 02:20

... logged and fragmented as a habitat type Almost all such forests on state and private lands had already been cut, and those stands remaining on National Forests and lands managed by the Bureau of Land ... victorious and excused them from liability if they lost In addition to incorporating new information and understanding from ongoing research and consultations with technical experts, land and wildlife ... in varying degrees and aspects — to other federal lands and to state and local jurisdictions and ownerships The National Environmental Policy Act of 1970 required that all land management activities

Ngày tải lên: 12/08/2014, 02:20

... vectors and wildlife hosts and their shared pathogens, making humans more likely to be infected with exotic viruses such as Ebola, jungle yellow fever, Nipah, and HIV The expanding demand for wood and ... destruction of more and more tropical and temperate forests and exposes forest and agriculture workers and their families to disease pathogens such as Ebola in Africa, yellow fever and arenaviruses ... the past 40–50 years and farmland gradually reverted to meadows, shrubs, and secondary growth woodlands that provided food and shelter for increasing populations of deer and rodents These habitat

Ngày tải lên: 12/08/2014, 02:20

... inbreeding, genetic drift, and population size and structure Wright’s 1968, 1969, 1977, and 1978 volumes provide a thorough and extensive overview of population genetic theory Theodosius Dobzhansky ... population genetics and evolutionary theory, theoretical aspects of selection and estimation of genetic parameters; The Genetical Theory of Natural Selection (1930) unified natural selection and population ... Wright and Fisher, arguably provide the foundation of population genetic theory Haldane’s mathematical approach provided insights into the interaction of selection and mutation, and to understanding

Ngày tải lên: 12/08/2014, 02:20

... island, and the island’s distance from the nearest mainland; smaller islands have larger extinction rates and islands closer to the mainland receive more immigrants The deep simplicity of island ... Lima and Zollner 1996; Sutherland 1998; Caro 1999; Anthony and Blumstein 2000) For example, optimal foraging theory is used to predict why and how individuals move through the landscape, and this ... century The theory of island biogeography (MacArthur and Trang 6Wilson 1967), and associated concepts of food webs and predator–prey dynamics, all emerged from these trails of inquiry and greatly

Ngày tải lên: 12/08/2014, 02:20

... the system of land surveys, land policy, land tenure, and farming methods in the West, and a denial of almost every cherished fantasy and myth associated with the westward migration and the American ... centuries, the feudal and aristocratic system of land ownership and commerce lay in collapse, as multiple famines and disease outbreaks swept across Europe And yet, much of the property and associated ... remaining use of rangelands in America’s food system Hunting and observing wildlife is now bargained for, as reflected by land prices, lease rates, and state and federal laws and regulations Places

Ngày tải lên: 12/08/2014, 02:20

... INVESTIGATION AND PHARMACEUTICAL APPLICATIONS OF CHLORIN e6 IN BIODEGRADABLE CARRIERS SHUBHAJIT PAUL NATIONAL UNIVERSITY OF SINGAPORE 2013 Trang 2PHOTOPHYSICAL INVESTIGATION AND PHARMACEUTICAL APPLICATIONS ... Enhanced permeability and retention effect Trang 21 Conservative force between beads, i and j Dissipative force between beads, i and j Random force between beads, i and j FBS Fetal ... specific band around 400 nm (Soret band) and four further specific bands in the region 500-650 nm [21] Photofrin® was marketed as the first generation photosensitizer by Axcan Pharma, USA in 1982 and

Ngày tải lên: 08/09/2015, 19:22

... superparamagnetic radius (rSP), induces a magnetic transition in particles where both ferro- and ferrimagnetic nanoparticles (FM) become superparamagnetic and, as previously said, high magnetic ... expressed by the magnetic volume susceptibility χ and the magnetic field strength H where the volume susceptibility is a constant for diamagnetic and paramagnetic substances and a function among ... immobilization, drug delivery and protein adsorption and purification [2,5,13-16] Magnetic separation involves magnetic particles, carrier liquids, complexes and target molecules Magnetic separation has

Ngày tải lên: 10/09/2015, 15:52

... Hetero -nuclear single quantum correlation spectrum M Molar ml Milliliter mm Millimeter ppm Parts per million rpm Rounds per minute µl Micro liter MRS Nuclear magnetic resonance spectroscopy NMR Nuclear ... spectroscopy NMR Nuclear magnetic resonance NOE Nuclear Overhauser effect NOESY Nuclear Overhauser enhanced spectroscopy RMSD Root-mean-square deviation TOCSY Total correlation spectroscopy ix TROSY ... information, and can help clinical investigators in understanding the role of metabolites in normal and pathological conditions In recent years the biomedical and in vivo applications of 1H spectroscopy...

Ngày tải lên: 10/11/2015, 11:35

... 1D and 2D NMR data, Journal of Magnetic Resonance 183(1): 145 151 24 22 Magnetic Resonance Spectroscopy Magnetic Resonance Spectroscopy Cobas, J C & Sardina, F J (2003) Nuclear Magnetic Resonance ... Resonance Spectroscopy Magnetic Resonance Spectroscopy Metz, K R., Lam, M M & Webb, A G (2000) Reference deconvolution: A simple and effective method for resolution enhancement in Nuclear Magnetic Resonance ... MRS signals of 10 Magnetic Resonance Spectroscopy Magnetic Resonance Spectroscopy human brain using HLSVD with a model order of 25 (K = 25) Nevertheless, suppression of unwanted resonances of in...

Ngày tải lên: 17/03/2014, 02:20

... TFA Salt Stoichiometry Solid-state Nuclear Magnetic Resonance  NMR in solids, like solution-state, relies on the behavior of nuclear spin energy levels in a magnetic field However, the interactions ... see P G Morris, NMR Imaging in Medicine and Biology, Oxford University Press, 1986 12 Magnetic Resonance Force Microscopy  A “combination” of AFM and EPR (and hopefully NMR)  Uses a nano-scale ... correlated spectroscopy HMQC heteronuclear multiple quantum coherence 1H-13C covalent bonding, bond HMBC heteronuclear multiple bond correlation 1H-13C NOE difference, NOESY, ROESY nuclear Overhauser...

Ngày tải lên: 27/06/2014, 01:20

... of electron and nuclear spin 1936: C J Gorter (Netherlands) attempts to study 1H and 7Li NMR with a resonance method, but fails because of relaxation 1945-6: E M Purcell (Harvard) and F Bloch ... Bodenhausen, and A Wokaun, “Principles of Nuclear Magnetic Resonance in One and Two Dimensions”, Oxford, 1987 C P Slichter, “Principles of Nuclear Magnetic Resonance , Springer-Verlag, 1996 20 ... www.nobelprize.org Nuclear Magnetism  A nuclear electromagnet is created by the nucleons (protons and neutrons) inside the atomic nucleus  This little electromagnet has a magnetic moment (J T-1) – The magnetic...

Ngày tải lên: 27/06/2014, 01:20

... hands and feet in a posterior-anterior projection was performed within a month of the US X-rays of both hands and feet (2nd–5th MCP, PIP, DIP, and MTP joints) were assessed for bone erosions and ... x-ray and not by US were in the non-MRIexamined hand However, x-ray erosions (all in PsA: MCP and DIP joints) and proliferations (both PsA: DIP joints) were located in the MRI-examined hand and ... ultrasonography (US) and magnetic resonance imaging (MRI) appear promising MRI can detect inflammation and bone destruction in joints earlier than projection radiography (x-ray) in PsA, RA, and spondyloarthritis...

Ngày tải lên: 09/08/2014, 10:21

... describing C Kleinstreuer, Modern Fluid Dynamics: Basic Theory and Selected Applications in Macro- and Micro-Fluidics, Fluid Mechanics and Its Applications 87, DOI 10.1007/978-1-4020-8670-0_1, © ... traditional and modern fluid dynamics, i.e., the fundamentals of and basic applications in fluid mechanics and convection heat transfer with brief excursions into fluid-particle dynamics and solid ... Definitions and Concepts A sound understanding of the physics of fluid flow with mass and heat transfer, i.e., transport phenomena, as well as statics/dynamics, stress–strain theory and a mastery...

Ngày tải lên: 02/04/2014, 14:53