... main component of environmental tobacco smoke, burns off the end of a lit cigarette and is the smoke inhaled by passive smokers While the association between inhalation of mainstream smoke and ... Trang 2environmental tobacco smoke can produce adverse effectson cardiovascular and lung health and encouraged broader investigation in this area [17] Subsequently, a number of studies have addressed ... either active or pas-sive, and the type of smoke inhaled in each case has a dif-ferent origin Mainstream smoke is the smoke that an active smoker inhales with each puff, while sidestream smoke,
Ngày tải lên: 05/03/2014, 17:20
... Analysis of Inbound Logistics Activities Correlation Analysis Cost Advantage Access to Quantity Advantage Faster/Earlier Delivery Advantage Customized Arrival Advantage Trang 11Comparison of Results ... the faculty and staff of the Department of Management, especially Dr Sang M Lee, Linda Rohn, and Cathy Watson The author would especially like to thank Annette and Hillary Samaras, who sacrificed ... demonstrated by fashion apparel manufacturers who are continuously changing their short term differentiation advantages In fashion apparel, the advantages of differentiated products are frequently made
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Missense mutations as a cause of metachromatic leukodystrophy Degradation of arylsulfatase A in the endoplasmic reticulum potx
... influence of glucosidase and mannosidase inhibi-tion on the mutant ASAs (Gly86Asp, Tyr201Cys, Asp335Val, Pro136Leu, Asp255His, Thr274Met) In these experiments all of the mutant ASAs behaved rather ... h; Asp255His, 4.5 h; Pro136Leu, 8 h) After the chase ASA was immunoprecipitated from the homogenates with the polyclonal ASA antiserum Precipi-tated ASA was quantified after SDS ⁄ PAGE with a ... a1,2-mannosidase I inhibition on ER exit of amino acid-substituted ASAs In order to investigate whether stabilization of mutant ASAs through inhibition of ER a1,2-mannosidase I via Kif can lead
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... signalregulated kinase ⁄ (ERK1 ⁄ 2) and protein kinase B (PKB) pathways that act downstream of oncogenic protein kinases [10,11] It is increasingly apparent that BIM as a mediator of tumour cell death ... pathway, the PKB pathway and the Janus kinase ⁄ signal transducer and activator of transcription (JAK-STAT) pathway, to promote proliferation, survival and transformation [56,57] The importance ... protein kinase ⁄ extracellular signal-regulated kinase kinase ⁄ kinases: mechanism of action in vivo, pharmacokinetic ⁄ pharmacodynamic relationship, and potential for combination in preclinical models
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library pdf
... Identification of calreticulin as a ligand of GABARAP by phage display screening of a peptide library Jeannine Mohrluder1,2, Thomas Stangler1,2, Yvonne Hoffmann1,2, Katja Wiesehan2, Anja Mataruga3 ă and ... folded GABARAP [22] The addition of CRT to GABARAP resulted in the disappearance of GABARAP resonances, a clear indication of binding (Fig 3B) Only weak amide signals for a Gln ⁄ Asn side chain and ... response Rmax was fitted as a separate parameter for each binding sensorgram The dissociation constant was obtained as Kd ¼ koff ⁄ kon NMR All NMR spectra were recorded at 25 °C on a Varian (Darmstadt,
Ngày tải lên: 16/03/2014, 05:20
The welfare state as a determinant of women’s health: support for women’s quality of life in Canada and four comparison nations pptx
... (adapted from International Reform Monitors, 2002) Canada: Canada’s national health care act stipulates the provision of health care to be an entitlement However, administration of health care ... inequality and poverty Ottawa: Status of Women Canada; 2001 [5] Day S, Brodsky G Women and the equality deficit: the impact of restructuring Canada’s social programs Ottawa: Status of Women Canada; 1998 ... increasing poverty and low income threatens Canadians’ health and health care system Canadian Review of Social Policy 2003;51:9–28 [19] Raphael D, Bryant T The limitations of population health as
Ngày tải lên: 22/03/2014, 11:20
Characterization of Spin Coated Polymers in Nano-environments as a Function of Film Thickness pot
... For each image, at least and as many as 12 height differences have been calculated and averaged together to give an overall feature height of each sample A summary of the averages is shown in ... nature, of the surface as the reaction time increased Also, an increase in the overall film thickness, as determined by ellipsometry, and an increase in the height, as demonstrated from AFM, measurements ... relationship of aT, explained as a ratio of relaxation times aT = τ ∗ (T ) / τ ∗ (TR ) (2) where TR is a reference temperature and T is the temperature of the measurement, was applied to Equation
Ngày tải lên: 23/03/2014, 01:20
Báo cáo khoa học: Lack of stabilized microtubules as a result of the absence of major maps in CAD cells does not preclude neurite formation pot
... GCTTGAAGGCGCTGGATCTGCGACAATAG GACTGGGCTTTCATCAGCGACAGGTGGC 91489–91517 92431–92404 NC_000067 Idem Tau-for Tau-rev GTGAACCACCAAAATCGGAGAACGAAGC CAGGTTCTCAGTAGAGCCAATCTTCGACCTGAC 78772–78800 79013–78981 ... LIS1-rev CGAACTCTCAAGGGC ATGCATCAGAACCATGCACG 1288–1303 1427–1407 NM_95116 Idem Tubulin a6-for Tubulin a6-rev AGCCCTACAATTCCATCCTCACC GCTGAAGGAGACGATGAGGGTGA 6854–6876 7646–7624 NC_000081 Idem Trang ... in parallel (Br) and revealed with antibodies to each of the MAPs For brain and CAD cells, the volume loaded in each lane was adjusted to contain equivalent amounts of total tubulin, as revealed
Ngày tải lên: 23/03/2014, 05:22
Fermentation as a Method of Food Processing ppt
... inoculated at the same time, large amounts Trang 28of aflatoxin was found The aflatoxin production of Aspergillus parasiticus was studied and found to increase in the presence of Lactococus lactis ... cultures of lactic acid bacteria had a wider range of activity against mutagensthan those produced with a single strain of lactic acid bacteria (Tamai et al., 1995). Antimutagenic properties of the ... with a range of 19.4-90.6%) in faecalmutagenicity compared to that before the administration as well as an increase in population of Lactobacillus spp and Bifidobacterium spp in the faeces of all
Ngày tải lên: 24/03/2014, 04:20
A Study on the Effects of Argentine Tango as a Form of Partnered Dance for those with Parkinson Disease and the Healthy Elderly pptx
... Trang 1Tango as a Form of Partnered Dance for those with Parkinson Disease and the Healthy Elderly Madeleine E Hackney1,5 Svetlana Kantorovich2 and Gammon M Earhart1,3,4 Falls are the leading ... increasing age (Rogers and Mille 2003) Gait changes associated with aging include decreased gait speed, decreased stride length, increased double support time, and increased width of the base of ... Stance Test (Vellas et al 1997) Walking velocity was assessed by tracking a reflective marker placed on the trunk using a motion capture system (Motion Analysis Corporation, Santa Rosa, CA) Measurement
Ngày tải lên: 28/03/2014, 20:20
scientific american - 2002 09 - special issue - a matter of time
... classified work to a separate domain So most ban classified research as a matter of policy and hold sacrosanct the concept of “basic research”— an of cial term delineating certain categories ... Silver ASSOCIATE PUBLISHER, STRATEGIC PLANNING: Laura Salant PROMOTION MANAGER: Diane Schube RESEARCH MANAGER: Aida Dadurian PROMOTION DESIGN MANAGER: Nancy Mongelli GENERAL MANAGER: Michael Florek ... mercury, lead, fiberglass, sulfuric acid and particulate matter of varying sizes. Thomas A. Cahill, an atmospheric scien- tist at the University of California at Davis, is most worried about the particulates.
Ngày tải lên: 12/05/2014, 16:14
báo cáo sinh học:" Migration as a form of workforce attrition: a nine-country study of pharmacists" pptx
... based on the interest of local pharmacy student asso- ciations to participate and willingness to gather data, and included Australia, Bangladesh, Croatia, Egypt, Nepal, Sin- gapore, Slovenia, ... States of America: measures of the African brain drain. Human Resources for Health 2004, 2:17. 3. Hagopian A, Ofosu A, Fatusi A, Biritwum R, Essel A, Gary Hart L, et al.: The flight of physicians ... final-year pharmacy students from nine countries: Australia, Bangladesh, Croatia, Egypt, Portugal, Nepal, Singapore, Slovenia and Zimbabwe. Data were analysed by means of Principal Components Analysis
Ngày tải lên: 18/06/2014, 17:20
báo cáo hóa học: " Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults" pptx
... to indicate whether they had a disease or another health condition diagnosed by a health professional that had lasted, or was expected to last, 6 months or more These data were used to classify ... several health outcomes that are important to quality of life Physical activity of at least 1,000 Kcal per week was associated with relatively fewer mobility limitations, reduced pain, and greater ... condition varia-ble, and physical activity was specified as a mediator of this relationship The Pratt-Index (d) [25] was used to par-tition the R-square so as to determine the relative impor-tance of
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Behaviour of motor unit action potential rate, estimated from surface EMG, as a measure of muscle activation level" potx
... of MUAPs, eMR was substantially lower than the actual MUAP Rate (aMR) The percentage of detected MUAPs decreased with aMR, but the relation between eMR and aMR was rather stable in all simulated ... Morphological, electrical and physiological parameter values were based on data of the biceps brachii (default values of the software package) For a full list of parameter settings, see Table 1 Simulation ... muscle is modelled as a one-layer cylindrical shape with a high axial and lower radial conductivity Fat and skin tissue is modelled as a peripheral layer (referred to as subcutaneous layer) where no
Ngày tải lên: 19/06/2014, 10:20
As A Matter Of Course pdf
... people and organizations in: Alabama, Arkansas, Connecticut, Delaware, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Information about Project Gutenberg Louisiana, Maine, ... immense amount of unnecessary nervous strain A spirit of rivalry has so taken hold of us and become such a large stone in the way, that it takes wellnigh a reversal of all our ideas to realize that ... counteract an unpleasant brain-impression by something pleasant but false We must call a spade a spade, but not consider it a component part of the man who handles it, nor yet associate the man with...
Ngày tải lên: 23/03/2014, 02:20
A Matter of Perspective - Point of View
... is clear, write the words used in paragraph B to replace the words in paragraph A The first replacement has been filled in to get you started PARAGRAPH A PARAGRAPH B usually always on time carefully ... ways to evaluate test results She has an extensive knowledge of the latest medical research, which has been invaluable What message does the writer of paragraph B convey about Nicole Bryan? a ... note A is more effective than the point of view of note B because a note A feels less formal b note A speaks personally to the reader c note A addresses the reader as an individual d all of the above...
Ngày tải lên: 25/10/2013, 17:20
Social Phobia as a Consequence of Brain Defects
... (accepting) accepting and negative and neutral expresssions: activation accompanied by in amygdala, evaluation of: hippocampus, Task performance: parahippocampal recognition of gyrus, medial type of emotion ... circuit (amygdala, hippocampus, insula, temporal lobe as well as anterior cingulate, medial, orbito, and dorsolateral prefrontal cortices) of social phobic patients are greater than those of controls ... physical signs with imbalances in autonomic neurotransmission In this formulation, the physical complaints typical of social phobia, are associated with rapid release of catecholamines (noradrenaline,...
Ngày tải lên: 01/11/2013, 08:20
Social Phobia as a Consequence of Cognitive Biases
... way as if through the eyes of an observer Again, it is difficult to grasp the meaningfulness of this finding, let alone as evidence of a bias However that may be, this putative ‘‘bias’’ is assigned ... treated as if originating in a scale of equal intervals This violates the basic postulates of the analysis of variance The relevant data should have been properly treated through some form of ... instance of a ‘‘category mistake.’’ According to Ryle (1949) this logical fallacy consists of treating the label for a class of events as if it were a member of that class From this vantage point...
Ngày tải lên: 01/11/2013, 08:20
Social Phobia as a Consequence of Inadequate Social Skills
... definitions aside, I shall now consider how the construct of social skills has been assessed in research Assessment of Social Skills of Social Phobic Individuals As the assessment of social skills had ... value of matching treatment with patients’ patterns of fear Based on extreme responses to a role-play and a ‘‘rationality’’ test, 39 patients were classified as either predominantly behavioral ... consider social phobia not as a breakdown in social ability but as emerging out of a pattern of meaningful actions that constitute a means to an end Although not necessarily abnormal in themselves,...
Ngày tải lên: 01/11/2013, 08:20