simulation of biological processes in the genome context

... rehabilitation clinic (clinical sample 2; Klinik Viktoriastift Bad Kreuznach, Federal State of Rhineland-Palatinate, Germany) and iii) within the city limits of Mainz and the rural district of Mainz-Bingen ... However, other factors affecting the individual burden of disease such as the social context and personality, have not been investigated in our study However, they might also explain some part of the ... condition The identification and rating steps of this algorithm are illustrated in Fig 1 This algorithm allowed the combination of information of the condition itself with information the condition’s

Ngày tải lên: 01/02/2020, 06:11

... similarly defined as the disdis-tance to the northern end of the GBR divided by the sum of distances to the northern and south-ern ends of the GBR This has the effect of mapping the GBRMP to ... values on the outer-shelf reefs of the northern half of the GBR (Figure 8) The spatial model explained 66% of variation in the data (Figure 9) P ATTERNS IN S OFT AND H ARD C ORAL C OVER Soft coral ... unrelated to that of the zooxanthellate hard and soft corals The total cover of soft and hard corals on the GBR remained uninfluenced by tur-bidity and sedimentation This finding indicates the potential

Ngày tải lên: 12/08/2014, 05:21

... large spatial mapping of salinities was needed to determine the origins of lower salinity events (34 ppt) within the reef matrix of the GBR Further, understanding the possible fates of river plumes ... plumes in the central section of the GBR DISCHARGE CHARACTERISTICS OF THE CENTRAL GBR REGION The rainfall catchment area adjoining and impacting the GBR Marine Park totals 424,000 km2not including ... including the influence from rivers intruding into the GBR from Papua New Guinea and Irian Jaya The mainland catchments have been divided into 35 drainage basins The two largest basins in this

Ngày tải lên: 12/08/2014, 05:21

... far-ther offshore in the GBRWHA have since been examined within the context of “out-welling”—the export of nutrients or organic detritus from fertile estuarine areas tosupport productivity of offshore ... in the western Indo-Pacific The early closure during any ice age of the shal-low Torres Straits seaway to the north of the GBR ensured that the Coral Sea was theprincipal connection in spread of ... estuaries, and there are very few euryhalinespecies in the south.Just offshore from the vegetated coastal fringe, the dominance of fine, terrige-nous sediments has produced an “estuarisation of the shelf”

Ngày tải lên: 12/08/2014, 05:21

... to line-fish in the offshore sections of these habitats rather than in the more accessible inshore edge of the reef shoal and inter -reef The rationale for these increasing ... par- ticular to the GBR or that were of particular interest in terms of the effects of fishing on the ecosystem. Initially these were the major commercial species of prawns and the discarded bycatch ... species vs. that of species found in the inshore reef lagoon. This spatial component to the model was explored further using the ECOSPACE simulation routine. The dynamic effects of the prawn fishery

Ngày tải lên: 12/08/2014, 05:21

... zones ofretention were in the south and southeast sectors where aggregations of fish generallyremained at or above the concentration of the incident plume DISCUSSION The findings of these two independent ... arafuensis was instrumental in distinguishing the late evening, far-grid community. con-The relevance of these key taxa in defining fish associations is evident from the composition of the four sample ... release to the water column of actively swimming larvae or juveniles, thus minimizing the time their off-spring are exposed to the vagaries of ocean or shelf currents and enhancing the 13 209

Ngày tải lên: 12/08/2014, 05:21

... frame of the animation The date assoasso-ciated with the 3-day animation is also indicated at the top of the key in the lower left of the screen As shown in Animation 3, the beginning of the warm ... mixing was another period of low winds only a week later, but unlike the northern section, this coincided with a maximum in the tidal range in the south, effectively maintain-ing mixmaintain-ing ... bleaching more often During the GBR 1998 bleaching event, bleaching only occurred in the absence of mixing In all bleaching cases, the winds were low Many reefs seemed to escape the bleaching temperatures

Ngày tải lên: 12/08/2014, 05:21

... and aesthetically. COMPARISON WITH THE LAND In thinking of the future of the Great Barrier Reef (GBR), we can learn from our treatment of the Australian landscape In the process of increasing agricultural ... scale for the “survival” in our heading should be considered? In the early part of the rising sea northeastern Australia’s aboriginal inhabitants would have experienced remark-able change in the GBR ... is at present insufficient care taken • In the use of its living resources • In planning its coastal zones • In environmental impact assessment of developments • In control of the final development

Ngày tải lên: 12/08/2014, 05:21

... Use of information and communication technologies in the processes of technological training in sustainable agriculture in the Brazilian context a literature review Uso das tecnologias da informação ... Based on the hypothesis that the use of ICTs in technological training in sustainable agriculture can contribute to the economic and social development of the territories, a literature review of articles ... to identify the contributions of technological training in sustainable agriculture made possible with the use of information and communication technologies [ICTs] in the Brazilian context and

Ngày tải lên: 11/10/2022, 16:25

... and moving back about 30 cm (placing their feet on a duct tape line on the floor), perching their infants at the front of their knees (not leaning back against their chest), and holding them tightly ... corner of the puppet stage and the box containing a colorful toy in the middle The Cow then entered from underneath the back curtain, but instead of moving forward and attempting to open the box ... lowering it in between as though unable to open the box During Prosocial Events, during the 5th struggle the Prosocial Pig (resting in the corner of the opposite side of the stage from where the

Ngày tải lên: 01/11/2022, 09:47

... (22-mers) of the viral genome is comprised of n-mers that are not present in any of the other dengue genomes For example, in the genome of the DENV-4 China Guangzhou B5 strain (AF289029), 75.4% of the ... sequences contained in any of their strain members For the 216-probe set, the minimum number of probes differentiating a DENV-1 strain from the all other strains belonging to one of the three other serotypes ... in the genome of interest and absent from the host genome as being ‘host-blind’ (human-blind, mosquito-blind, mouse-blind, rat-mouse-blind, etc.) sequences The greater the num-ber of changes necessary

Ngày tải lên: 23/03/2014, 11:20

... indication of the subject's own assessment of their health status on the day of the survey [13,25] The women in the present study were asked to complete the EQ-5D descriptive system and not the ... widely applied in the broader health-related quality of life literature [35-40] It is defined as the ratio of the square of the t-statistic of the comparator instrument (assumed to be the SF-6D utility ... and the saved young life equivalent (SAVE) [6] The QALY syn-thesises information on the length of life and the health-related quality of life into a single measure of health out-come, and is the

Ngày tải lên: 18/06/2014, 18:20

... concern the process of developing scienti¢c software The codes involved in simulation software are becoming larger and larger In engineering, they range from 50 000 lines to perhaps 000 000 lines of ... In that Empire, the art of cartography attained such perfection that the map of a single province occupied the entirety of a city, and the map of the Empire, the entirety of a province In ... on-line tools for data mining, homology searching, sequence alignment and numerous other analyses One of the best entry points for those interested in the burgeoning ¢eld of bioinformatics is the...

Ngày tải lên: 11/04/2014, 09:47

... part  of the lost  wave  energy  is  transformed  into  turbulence  energy.  At  the beginning  of the wave  breaking  process,  the turbulence  is  confined into a small portion of the breaking  ... wetted function is 1. For other cases, value of the cell  side  wetted  function  equals  to  the ratio of the length of the wetted portion over  the total length of the cell side. After getting  all the wetted points on four sides of the cell,  ... by  the dotted line in Fig. 1. The wetted area in cell i,j  in this  figure  is  the portion  of the cell  from  the dotted  line  to  offshore.  The wetted  periphery  and  area  inside ...

Ngày tải lên: 28/03/2014, 15:20

... abundant in the genomes of bacterial pathogens As expected, the authors confirmed that The Importance of Biological Interactions in the Study of Biodiversity the presence of these prophages was in ... selection in an environment such as a biofilm leads to the evolution of unequal interactions Specific mutations in the genome of one species lead to adaptation to the presence of the other The resulting ... detected in any section of the crypt region Biofilms are the leading cause of contamination of medical devices and in industrial and agricultural settings The initial adhesion and further colonization...

Ngày tải lên: 28/06/2014, 08:20

... found in the genome, in this case in the E coli genome The connection pattern of coloured boxes then indicates the presence of the bacteria-type lysine biosynthesis pathway Thus, given the reference ... clear about the functions of the database regarding the purpose of modelling According to the decision we have made at this stage of de¢ning the purpose of the database, there is a series of speci¢cations ... developing bioinformatics technologies for deciphering the genome in terms of the biological system at the cellular level; namely, in terms of systemic functional behaviours of the cell or the single-celled...

Ngày tải lên: 06/08/2014, 13:22

... experimental investigations o¡er the promise of providing data pertaining to the above steps A major challenge, then, is the organization of this data into knowledge in the form of hypothesis, models ... pathways Thus, if the digital signature of protein kinase A in two di¡erent pathways is the same, then the kinase is in the same functional state in the two pathways Middle tier The middle tier ... another selection to ¢nd the interacting partner The protein and its interacting partners will be displayed as nodes on the GUI Each node can now act as a further starting point, and the interaction...

Ngày tải lên: 06/08/2014, 13:22

... to the template in order to map points in this template to points in the target The bottom panel shows the result of applying the inverse mapping f to the target to take this target back into the ... surprising change in the apparent ¢bre orientation in the septum in the failing dog hearts Could this be due to something other than a change in the principal axis of the myocytes, and instead ... shows the result of applying the forward mapping f to the template (C), and the inverse mapping fÀ1 to the target (D); the right column shows the grids deformed by the forward mapping f (E) and the...

Ngày tải lên: 06/08/2014, 13:22

... eleven binary £ags Ten of these represent the state of binding or modi¢cation sites: aspartate binding (1); CheBp binding (2); CheR binding (3); methylation (4^7); phosphorylation (8); CheY binding ... residues on the cytoplasmic domain of MCPs Each added methyl group increases the activity of CheA in complex with the receptor, thereby counteracting the e¡ect of attractant binding Methylesterase/deamidase ... ignores the downstream phosphorylation cascade The full complement of receptor states should include, in addition, the binding of ligand in the periplasm and of the modi¢cation enzymes, as well as the...

Ngày tải lên: 06/08/2014, 13:22

... working in simulation studies in engineering or cosmology or in many other physical sciences And, in fact, the failure of the MNT model is one of the most instructive examples of experiment ^simulation ... point of view, they are also in uencing the younger scientists We shouldn’t be giving up on them From the point of view of the science of biology, there are many of these scientists and they are ... is the fate of insights that were hard-won at the time to become obvious later This review will also therefore serve the purpose of reminding readers of the role simulation played in gaining them...

Ngày tải lên: 06/08/2014, 13:22