roles and managing resistance to change in your company

... upgrading project The ultimate purpose of this study is to develop a framework which will be of use to practitioners for understanding and managing resistance to IS change Key Words: resistance to ... will be of use to practitioners for understanding and managing resistance to IS change, with specific reference to the project of upgrading VietBank’s core banking system At the baseline, the first ... during from 3/2020 to 9/2020 5/10 Trang 6The management literature has defined resistance to change as ‘the forces against change in work organisations’ (Mullins, 1999, p 824) Resistance to change

Ngày tải lên: 06/12/2024, 16:25

... leading to the accumulation of autophagosomal structures [42] Sequestosome 1 (p62) is an ubiquitin-binding adaptor protein, which binds to parkin-ubiquitinated mitochon-drial substrates and mediates ... cytoplasm in MCF-7CC10 cells, with a small amount of overlapping staining (yellow) In contrast, MitoTracker™ labeling and LC3-II staining in MCF-7DOX2–10 cells localized predominantly in the perinuclear ... the clustering of mitochondria and recruitment of ubiquitylated cargo into autophagosomes by binding to LC3 [51, 52] In fact, both ubiquitinated protein aggregates and dysfunctional mitochondria

Ngày tải lên: 20/09/2020, 18:07

... chemoresistance to doxorubicin, paclitaxel and cisplatin in AF-6/afadin strongly positive cell line To estimate chemoresistance to doxorubicin, paclitaxel and cisplatin induced by AF-6/afadin KD, ... specimens were cut into 3.5-μm sections for Trang 3hematoxylin-eosin staining and AF-6/afadin immunohisto-chemical staining Each experiment was performed three times Matrigel invasion assay Cells ... AF-6/afadin at the leading edge does not bind nectins, and enhances cell movement [10] Thus, AF-6/afadin has conflicting role in cell invasion AF-6/afadin loss induces cell migration, invasion, and

Ngày tải lên: 29/09/2020, 15:56

... progression and drug resistance The ability of released HMGB1 to trigger drug resistance in cancer cells is reportedly due to autophagy [52,53] In addition, autophagy can also play a role in anthracycline ... specific inhibitor (i.e glycyrrhizin) [55] or targeting its proposed receptors (RAGE and the toll-like receptor 4, TLR4) on cancer cells may prevent or inhibit the develop-ment of drug resistance In ... agent, in this case doxorubicin, (Dox), this increased intracellular HMGB1 can be released and may function in a paracrine manner to induce acquired chemoresistance of the nearby surviving cancer

Ngày tải lên: 30/09/2020, 13:21

... monitoring and mitigation of aflatoxin in food and feed crops This has led to an increased risk of exposure to aflatoxin resulting in outbreaks of acute aflatoxin poisoning (aflatoxicosis) [3] and ... of a genetic engineering approach in developing cotton with increased resistance to A.flavus infection and aflatoxin contamination will depend in large part on identification of resistance genes, ... with inhibition of aflatoxin included regions on chromosome arms 2L, 3L, 4S, and 8S and these may prove promising for improving resistance through marker-assisted breeding into commercial lines In

Ngày tải lên: 02/11/2022, 09:18

... capacities, success and failures in performance of institutions, explaining possibilities and constraints for institutional capacity building and performance, and identifying and contrasting lessons ... be done to enhance institutional capacity in each country to make local communities more resilient to hazards in the coming years Why are existing institutions and behavior of main actors not ... and networking activities: its approaches are in line with the foci of its GECHS programme which concentrates on exploring human vulnerabilities to global change and finding tools to increase resilience

Ngày tải lên: 22/10/2013, 10:15

... Resettlement ……… 100 2 FINDINGS FOR INDIVIDUAL RESPONDENTS………101 2.1 Initial Feelings towards Imminent Resettlement ………101 2.2 Words describing Initial Sentiments towards 3 FINDINGS FOR RESPONDENTS’ ... low-cost housing efforts to mitigate the effects of rapid urbanization Simply knowing the factors, and then installing them without understanding of the causal mechanisms behind how the factors influenced ... prevalently in Phnom Penh.” It is developing the National Housing Policy, and committing to a range of “guiding policies and commitments, including a Hundred Settlements Policy, to improve housing conditions

Ngày tải lên: 02/10/2015, 17:15

... factors and ECM signals for proliferation, and insensitive to apoptotic stimuli Peng et al linked PRL-3 to integrin signalling when they identified integrin α1 as a PRL-3 binding protein in HEK293 ... [19] Protein Tyrosine Kinases (PTKs) are classified as receptor or non-receptor tyrosine kinases Many signalling ligands act through cell-surface RTKs Ligand binding to RTKs leads to autophosphorylation ... discussed in Chapter 3 Joint integrin/receptor tyrosine kinase (RTK) signalling controls cell adhesion to the extracellular matrix (ECM) and response to growth factors [58] Integrins mainly signal

Ngày tải lên: 16/10/2015, 15:37

... examine how the idioms and proverbs relating to children are carried out Therefore, I think it is necessary to make an investigation into the English and Vietnamese idioms and proverbs relating to ... that contain the words relating to children and have the meaning denoting children, idioms and proverbs that contain the word denoting children but not relating to children, and idioms and proverbs ... analyzing idioms and proverbs relating to children in English and Vietnamese in terms of syntactic and semantic features o Analyzing to find out the semantic purposes of idioms and proverbs relating

Ngày tải lên: 14/05/2016, 18:38

... Titles in the Professional and Higher Education series include: 53 interesting things to do in your lectures 53 interesting things to do in your seminars and tutorials 53 interesting ways of helping ... write notes in a few minutes Attention is devoted to listening and thinking rather than being split between thinking and note-taking; b more questioning from students who, instead of copying down ... notes; using handouts; structuring and summarising content; linking lectures to each other; holding the students’ attention; active learning during lectures; and monitoring learning For each of

Ngày tải lên: 16/06/2017, 15:07

... English and Vietnamese in particular, I hope it will partly help learners Trang 9and translators avoid difficulties in realizing and translating English proverbs and idioms intoVietnamese and vice ... proverbs, metaphor , magazines,newspapers, etc in both English and Vietnamese in which whatever relating to idiomatic andproverbial expression containing ‘animals’ is taken into consideration Then ... language learningthough it may take a longer time and make language teaching and learning more challengingthan ever Trang 131.5 Literal meanings and idiomatic meaningsAccording to Dr Duong Ky

Ngày tải lên: 08/09/2018, 22:48

... 16Learning Culture and Employee EngagementTrang 17Developing a Unified Culture• Fully define your organization’s mission and values • Translate your values into actions and outcomes • Encourage your ... your managers and employees to work on personal and company-wide values-based goals Trang 18Learning Culture and Employee EngagementTrang 19Assess Your Employees’ Potential• Desire to Lead: Is ... 2.5x more likely to stay late Trang 27Mapping Skills to Desired OutcomesDelegation Listening Skills Leadership Strategic Thinking Trang 28bamboohr.com bizlibrary.comLearning Culture and Employee

Ngày tải lên: 30/11/2018, 18:23

... percentages of infected piglets associated with housing hygience, weanling pigs tend to avoid wind, and suckling piglets are thought to be more sensitive to wind than weanlings, owing to their thinner ... side and feed intake, daily gain, and protein and fat accretion on the other side This indicates that selection for increased survival will definitely influence finishing traits, but also that intense ... shortening and crypt deepening Furthermore, weaning piglets was also associated with villas shortening 10 and crypt deepening and giving supplementary feed during the suckling period was effective in...

Ngày tải lên: 21/06/2014, 06:20

... were involved in establishing and/ or maintaining the resistance to TA In that case, these changes could theoretically be reverted, resulting in the restoration of cell sensitivity to the inhibitor ... http://www.biomedcentral.com/1471-2229/10/272 Habituation to TA is associated with important transcriptional changes To study the genetic mechanisms that may be involved in TA resistance and in maintaining this resistance in TA(-)hab cells, ... upregulated in TA(-)hab cells Moreover, numerous genes encoding members of different transcription factors families, including WRKY, C2H2-type zinc finger protein, MYB and NAC domain containing proteins,...

Ngày tải lên: 11/08/2014, 11:21

... Our company is seeing changes in how consumers in general prefer to obtain access to goods and services 26 56 10 Our company is seeing changes in how our own customers prefer to obtain access to ... defining financial oversight rules and insurance requirements to establishing data security guidelines for information exchange and collection, regulators are being forced to rethink how these industries ... subscription goods and services to our business model 40% We are integrating shared goods and services to our business model 27% We are integrating leasing/rental goods and services to our business model...

Ngày tải lên: 04/12/2015, 00:19

... VIETNAMESE IN TERMS OF In this section, we will analyse one word in each meaning syntactically namely hear and nghe in meaning 1, listen and l ng nghe in meaning 2, overhear and nghe l m in meaning and ... listen in English and nghe in Vietnamese Thirdly, WRHs in four meanings can combine with N or NP whose meanings relate to sounds Fourthly, the number of WRHs of the meaning and meaning in English and ... outstanding individual property of the word.” And the lexical and the closed classes or empty word-forms And in this paper, we meaning of the word can be classified in to denotational meaning and...

Ngày tải lên: 26/11/2013, 13:31

... areas, including: • Designing and implementing risk-based federal and critical infrastructure programs Shortcomings persist in assessing risks, developing and implementing controls, and monitoring ... areas, including designing and implementing risk-based programs; detecting, responding to, and mitigating cyber incidents; promoting education, awareness, and workforce planning; promoting R&D; and ... analysis and warning capability Difficulties in sharing and accessing classified information and the lack of a centralized information-sharing system continue to hinder progress According to DHS,...

Ngày tải lên: 20/02/2014, 05:20

... the meeting is to be kept in control, the chairperson must ask participants to indicate intention to speak by raising a hand, then noting and keeping to a strict order of the contributors In larger ... years teaching experience Training experience Extensive experience in training, and training of trainers for international, national and local organisations Computer literacy Recent update in MS Office ... 23 7.4 CHAIRING A MEETING 4.1 The Role of the Chairperson 4.2 Observing Protocols and Voting 4.3 Managing the Meeting 4.4 Concluding the Meeting 26 7.5 MEETING RECORDS 5.1 Types of Minutes 5.2...

Ngày tải lên: 31/03/2014, 18:20

... chức công (Theories about Organizational change in Public Organization)  Các nhân tố đóng góp vào thay đổi thành công (Factors contribute to successful change) LÝ THUYẾT VỀ THAY ĐỔI TỔ CHỨC Ở ... thuyết xem hành động có mục đích quản lý hành động dẫn dắt thay đổi (driving change) - Lawrence and Lorsch 1967, Pfeffer and Salancik 1978 Những nghiên cứu khu vực công cung cấp chứng cho vài ... thay đổi Yếu tố 3: Xây dựng hỗ trợ nội để thay đổi vượt qua kháng lực (Build internal support for change and Overcome resistance)  Các nhà lãnh đạo phải xây dựng hỗ trợ nội để thay đổi làm giảm...

Ngày tải lên: 16/04/2014, 02:30

... frequent and responsive symptom domains Flow diagram of 28 symptom domains in questionnaire and criteria for determining frequent and responsive symptom domains Sixteen symptom domains were included ... clinical trials, including molecules targeting interleukin 12, interleukin 17, and endothelial integrins The efficacy of UC therapies in clinical trials is assessed with disease activity indices that ... 2: Symptom domains and their frequency and responsiveness to changes in disease activity Frequent and Responsive Symptoms (n = 13) Infrequent or Unresponsive Symptoms (n = 15) Symptom Domains Derived...

Ngày tải lên: 18/06/2014, 19:20