role of oxidative stress and antioxidants in male infertility

... determination of apoptotic markers (DNAF in testes homogenate and calcium ions in mitochondrial matrix) Also, OS Fig. 1  Structure of hesperidin Page of 11 markers including ROS [such as MDA and ... of venous insufficiency and hemorrhoids [9] A deficiency of H in the diet has been linked with abnormal capillary leakiness as well as pain in the extremities causing aches, weakness and night ... range of pharmacological properties [10] Therefore, the present study was carried out to investigate the role of H in minimizing the testis damage induced by γ-radiation in a total dose of 8 Gy

Ngày tải lên: 04/12/2022, 16:05

... creatinine] Figure 1 Levels of 1-OHP, 8OHdG and reducing species in urine. Concentrations of 1-OHP (a), 8OHdG (b) and reducing capacity (c) in urine samples of workers, presented as a function of ... smoking status and time of sampling. Concentrations are expressed as μmol/mol creatinine for 1-OHP, μg/g creatinine for 8OHdG, and μW/g creatinine for the reduced species. Horizontal line in the ... response of the organism to particle-induced oxida- tive stress. The observed increase of reducing species in urine would mirror an increased level in blood originat- ing from a response to oxidative

Ngày tải lên: 20/06/2014, 00:20

... role of oxidative stress We also aimed at evaluating the role of protein kinase C (PKC) in the putative glucose-induced, oxidative stress-mediated impairment of the NO-cGMP signalling in VSMC, since ... endothelial and in the media layers of the aorta, indicating the occurrence of a PKC-mediated increase of oxidative stress in VSMC, the main component of the media [40] Furthermore, acetylcholine induced ... phosphorylation induced by the NO/cGMP signalling, underlining the role of oxidative stress in this phenomenon Our working hypothesis was that high glucose increases in a short-term oxidative stress by

Ngày tải lên: 02/11/2022, 08:46

... setting of obesity Impact of reduction in obesity in attenuating inflammation, oxidative stress and generation of vasoconstriction and ROS Undoubtedly, increased oxidative stress, ROS and in-flammatory ... than in control and obese reduction, and significantly lower in obese reduction than in control (all p<0.001) Protein and mRNA expressions of markers of vasoconstriction and oxidative stress in ... protein expressionsof oxyblot (i.e., protein carbonyls) (Figure 3), an index of oxidation, and mRNA and protein expressions of NOX-1 and NOX-2 (Figure 4), two indices of ROS, were signifi-cantly increased

Ngày tải lên: 02/11/2022, 09:23

... Processing’ 113 and 75 proteins were involved in translation and folding, sorting and degradation of ‘Genetic Information Processing’ respectively In ‘Metabolism subcategory’, large proportion of ... with those in IS including 36 unknown proteins and 213 identified proteins, and 319 differential proteins in MS compared with those in DS Strikingly, nearly half of quantified proteins were expressed ... long-chain specific acyl-CoA dehydrogenase It was involved in the initial step of mitochondrial beta-oxidation of straight-chain fatty acids and in the maintenance of an internal steady state of lipid

Ngày tải lên: 19/03/2023, 15:29

... ples and deposits When interpreting the results of the chemi- cal analysis of rainwater and deposits it is necessary to bear in mind the interactions between the matrix and ... needle are released during rinsing. In the rainwater samples there can be interferences with atmospheric dust and dry deposits of non- marine origin. In any case, the highly ... &mdash; treatment of P pinea in the open field The following sets of tests were made: - NaCl in varying concentrations (0, 30, 60 and 120 g/l); - NaCl in a single concentration

Ngày tải lên: 08/08/2014, 19:21

... Such strategies included increasing the reading activity of nurses, teach- ing research critique and appraisal skills, and offering a variety of educational programs targeted at the individual [9]. ... understanding and use of P&Ps also play key roles. Thus, moving research evidence into practice will require careful interplay between the organization and the individual. P&Ps may be the interface ... in the Canadian province of Newfoundland and Labrador with the specific aim of understanding the role of P&Ps in pro- moting research utilization. Theoretical framing No theory or conceptual

Ngày tải lên: 11/08/2014, 05:22

... amino acids of which two are within the third extracellular CAT-1 loop that contains the virus binding site: I214V, and a glycine insertion within the YGE virus binding site [6]. As shown in the present ... 88) and MA139 (ferret, obtained from J. Hartley). Cells were trypsinized and passed 24 hours after transfec- tion and maintained in medium with 0.8 mg/ml geneticin (Invitrogen, Grand Island, ... transfectants of MA139, Tb-1-Lu and MDCK cells were infected with a panel of ecotropic gammaretro- viruses including two, Spl574 and F-S MLV that induce multinucleated syncytia in M. dunni cells but not in

Ngày tải lên: 13/08/2014, 06:20

... 2002) Cholesterol in the brain may play an important role in synaptic development and plasticity, brain growth, neuron repair and remodeling, and even maintaining the normal function of this important ... vesicle tethering, and are involved in modulation of cellular cholesterol transport and homeostasis In this study, I demonstrate inhibition of intracellular cholesterol trafficking in primary neurons ... cleave a variety of intracellular polypeptides, including major structural elements of the cytoplasm and nucleus, components of the DNA repair machinery, and a number of protein kinases, which then

Ngày tải lên: 14/09/2015, 14:06

... policies in determining performance, as measured by growth and inflation In this section we also study the time profile of output and inflation in transition economies taking initial conditions and ... the Central and Eastern Europe (CEE) and the former Soviet Union (FSU) China and Vietnam have contained inflation and benefited from continued high growth in GDP since the beginning of their reforms, ... problems include difficulties in estimating deflators; difficulties in deriving consistent measures of trade and balance of payments over time; over-reporting of output at the beginning of transition

Ngày tải lên: 30/08/2016, 07:40

... manufacturing in low-income countries, Kumar and Managi (2012) on states in India, Wang and Szirmai (2013) and Bas and Causa (2013) on China, and the case of the manufacturing sector in Viet Nam ... in 1985 in Helsinki, Finland, as the first research and training centre of the United Nations University Today it is a unique blend of think tank, research institute, and UN agency—providing a ... capital and process innovation Meanwhile, Kumar and Managi (2012) showed that productivity changes could vary and spread across regions in India Concerning the influence of innovation and the

Ngày tải lên: 13/01/2020, 18:01

... manufacturing in low-income countries, Kumar and Managi (2012) on states in India, Wang and Szirmai (2013) and Bas and Causa (2013) on China, and the case of the manufacturing sector in Viet Nam ... Model 1: Role of innovation (b) Model 2: Role of innovation and environmental practices (c) Model 3: Role of innovation, environmental practices, and firm characteristics (d) Model 4: Role of innovation, ... in 1985 in Helsinki, Finland, as the first research and training centre of the United Nations University Today it is a unique blend of think tank, research institute, and UN agency—providing a

Ngày tải lên: 16/01/2020, 11:45

... now investigated the role of EGFR signalling in the stimulation of migration by LPA Blocking of the EGFR with the EGFR tyrosine kin-ase inhibitor gefitinib or the EGFR antibody cetuximab inhibited ... migration and invasion in several cancers, including ovarian, pancreatic, various gastro-intestinal, and oral carcinomas [22,39] Clarification of the mechanisms underlying LPA-induced cell migration in ... is important to understand in detail 1 Department of Pharmacology, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, and Oslo University Hospital, Blindern, P.O Box 1057,

Ngày tải lên: 14/10/2020, 17:15

... high-check, casual-dining and fine-dining restaurants (Goldman, 1993) For the purpose of this thesis, upscale ethnic restaurant population consists of casual and fine dining units offering full service, ... as good looking when they are on job duty (Nickson et al., 2005) Training methods: on-job training/ off-job training There are two types of training methods Under off-job training approach ... The following part declares the necessity of people training and development to improve staff skill in a context of less training practise in the hospitality due to unawareness of training benefits

Ngày tải lên: 24/03/2021, 17:39

... demands for safer and more natural products are increasing, mainly in food, cosmetic and medicine industries One of the most important opportunity to deal with this kind of demands is the use of ... providing this early version of the manuscript The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form Please note that during ... N and 99° 24’ 01’’ W) at 1 100 masl within a warm subhumid climate with rains in summer, including an average annual temperature of 18 ℃ and average annual precipitation of 900 mm The predominant

Ngày tải lên: 04/12/2022, 15:45

... results of this study will contribute to the understanding of the role of vocabulary depth and breadth in academic writing skills in higher education students The findings will provide valuable information ... to completing the sentences by filling in the blank and adding punctuation Data is analysed by Markin4 and SSPS 3.2 Sampling & population Participants included 50 students majoring in English ... no change in the percentage of academic vocabulary used in the students' writing after 12 weeks, in contrast to Storch and Tapper's (2009) findings and hypothesized that the time frame of 12 weeks

Ngày tải lên: 30/06/2023, 17:07

... meeting the needs of employees Following is a review of the history of coaching in business to give further understanding of the context in which coaching arose History of Managerial Coaching ... 10Chapter {: Introduction Coaching Defined History of Managerial Coaching Origin of the Term The Evolving Role of the Manager Coaching in Organizations: The Early Years Coaching in Organizations: ... terms of what the coach does, “interviewing and counseling with a focus on reality problems” (Levinson, 1996, p 116); and in terms of business results, “facilitate private individual learning in

Ngày tải lên: 02/01/2024, 21:38

... problems of contract law which, by proving convincing and becoming accepted in practice, could grow into new general principles As to the legal status of the PICC, the principles are a non-binding ... Trang 1MINISTRY OF EDUCATION & TRAININGHO CHI MINH CITY UNIVERSITY OF LAW The role of UNIDROIT PICC and CISG in international sale of goods contract, can UNIDROIT ... discerning underlying general principles 11 Ingeborg Schwenzer, INTERPRETATION AND GAP-FILLING UNDER THE CISG, 7.4 THE CISG AND THE PICC. 12 Ingeborg Schwenzer, INTERPRETATION AND GAP-FILLING UNDER

Ngày tải lên: 17/04/2024, 09:46

... problems of contract law which, by proving convincing and becoming accepted in practice, could grow into new general principles As to the legal status of the PICC, the principles are a non-binding ... Trang 1 MINISTRY OF EDUCATION & TRAINING HO CHI MINH CITY UNIVERSITY OF LAW The role of UNIDROIT PICC and CISG in international sale of goods contract, can UNIDROIT ... discerning underlying general principles 11 Ingeborg Schwenzer, INTERPRETATION AND GAP-FILLING UNDER THE CISG, 7.4 THE CISG AND THE PICC 12 Ingeborg Schwenzer, INTERPRETATION AND GAP-FILLING UNDER

Ngày tải lên: 10/09/2024, 22:11

... Nonretained proteins were washed out with 20 m M triethanolamine buffer pH 8.0 and retained proteins were eluted using a gradient of NaCl prepared in the same initial buffer. The presence of the ... clearly increased. Actually, the substitution of R97 by methionine or lysine resulted in the same increment in the pK a of E399 (Table 2). Therefore, M97 and K97 are equally effective in stabilizing ... to E187, in order to minimize unfavourable interactions with the apolar side chain of F331. Thus, the increment in the pK a of E399, in addition to it being closer to E187, may have resulted in a...

Ngày tải lên: 23/03/2014, 15:21