role of airway surfactant in chronic obstructive pulmonary diseases

... different parameters for tolerance, r (0.1→0.5 in intervals of 0.1) and embedding Trang 7dimension, M (1→5 in intervals of 1); 20 out of 25 (80%) of these combinations were viable when considered physiologically ... this zone of values more intensively Once more, we fix values for M and r There are values for tolerance, r (0.01→0.25 in intervals of 0.01) and embedding dimension, M (1→5 in intervals of 1) For ... Note: 1000 RR-intervals were required in the calculations for each subject where, tolerance is r (0.01→0.25 in intervals of 0.01) and embedding dimension is M (1→5 in intervals of 1) The physiologically

Ngày tải lên: 30/10/2022, 19:09

... recording time Accordingly, in addition to the traditional threshold of 30% of the time with a saturation < 90%, the effect of Table 1 Schedule of follow-up procedures, including a fourth year of ... challenge since the beginning of the trial in November 2009 It has become obvious that the target sample size of 600 patients would not be reached within a reasonable period of time In order to increase ... heartdiseases, interstitial lung diseases, bronchiectasis as the main cause of obstructive disease, lung carcinoma, severe obesity (body mass index≥ 40 kg/m2 ), or any other disease that could influence

Ngày tải lên: 04/12/2022, 15:45

... providing this early version of the manuscript The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form Please note that during ... Terminology ICD-9 - International Classification of Diseases, Ninth Revision ICS – Inhaled corticosteroids IQR - Inter-quartile range LABA - Long acting beta agonists LAMA – Long acting muscarinic ... Philips-Respironics, Inc The funding institution did not have any role in the design, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and

Ngày tải lên: 04/12/2022, 16:04

... is, an acute bout of pulmonary inflammation involving increased secretion of purulent sputum) in 9 patients, abdominal surgery in 2 patients, and gastrointestinal hemorrhage in 1 patient Three ... day) nitroglycerin Nitroglycerin was admi-nistered by continuous intravenous infusion starting at the beginning of the spontaneous breathing trial, and its dose was titrated to maintain normal systolic ... second day with (Study day) nitroglycerin continuous intravenous infusion starting at the beginning of the spontaneous breathing trial, and titrated to maintain normal systolic blood pressure Hemodynamic,

Ngày tải lên: 13/08/2014, 21:21

... robustness of the results by investigating the effects of including and excluding studies with high risk of bias and studies with missing information All evidence will be presented in a standardized ... Thomson MA. Closing the gap between research and practice: an overview of systematic reviews of interventions to promote the implementation of research findings.(Getting Research Findings into Practice, ... implementing guidelines: article 13 in integrating and coordinating efforts in COPD guideline development An official ATS/ERS workshop report In., vol 9; 2012: 298-303. 15 Marciniuk DD, Goodridge D, Hernandez

Ngày tải lên: 24/11/2022, 17:41

... men The increasing incidence of COPD is reflected in increasing health care costs to treat and care for pa-tients The total cost of COPD in the U.S was ap-proximately $32 billion dollars in 2002 ... of statistical in-ference and underpins the basis of probability theory [18, 19] Gotway and Young [17] outline a combination of spatial smoothing and geostatistical upscaling or aggregation of ... specific to smoking as are other diseases typically included in the spectrum of illnesses falling under the rubric of COPD We should also mention that our information re-garding COPD charges

Ngày tải lên: 26/10/2012, 09:57

... drug to drug interactions [12] The collective results of inhaled corticosteroid/long-acting beta-2 ago-nist combination are summarized in figure 2 In total, there were 269 deaths in the inhaled corticosteroid ... reference group of the trial in order to pre-serve the integrity of the original trial design and avoid Figure 3 The Effects of Inhaled Corticosteroid/Long-Acting Beta-2 Agonist Combination on Total ... combination may also attenuate the systemic inflammatory response in COPD Figure 4 The Effects of Inhaled Corticosteroid/Long-Acting Beta-2 Agonist Combination on Total Mortality Using Clinical

Ngày tải lên: 12/08/2014, 11:21

... risk Chronic obstructive respiratory disease (CORD) is defined as chronic obstructive diseases of the airways and pulmon-ary tissues CORD includes a wide array of serious dis-eases, and chronic obstructive ... overfitting, yielding spurious findings, which made a large 95% CI for OR in our analysis Increasing the sample size and collecting more IBPA cases in a further study may avoid this kind of limitation ... Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongren Tiyuchang South Road, Beijing, 100020, PR China Full list of author information

Ngày tải lên: 14/08/2014, 07:21

...   of   Chronic obstructive pulmonary disease in Que Vo and Thuan Thanh districts, Bac Ninh province in 2015 2). Analyzing some factors related to Chronic obstructive pulmonary disease in the studied area ... 3. New contributions of the thesis: 1) Epidemiological characteristics of Chronic obstructive pulmonary disease in Que Vo and Thuan Thanh districts of Bac Ninh province in 2015: The overall prevalence of Chronic obstructive pulmonary disease in Que  ... 3)   Evaluating   the   effectiveness   of   a   number   of   intervention measures   against   Chronic   obstructive   pulmonary   disease   in   Que   Vo district, Bac Ninh province 3. New contributions of the thesis:

Ngày tải lên: 17/07/2020, 23:29

... and MeSH terms referring to inhaled corticosteroid and the risk of URTI were used as search terms, including “Pulmonary Disease, Chronic Obstructive” OR “chronic obstructive pulmonary disease” ... of blinding of participants and personnel bias, 1 study had high risk of blinding of outcome assessment bias, and 1 study had high risk of incomplete outcome data One study had unclear risk of ... (participants, interventions, comparators, outcomes and study design) [18] Inclusion criteria included: (1) patients with COPD; (2) The interventions included any type of inhaled corticosteroids, including

Ngày tải lên: 05/05/2021, 03:28

... person Informed consent During the process of obtaining informed consent for Phase 1, participant’s interest in engaging in Phase 2 and/or Phase 3 of the project will be ascertained Expres-sion of ... six stages of the-matic analysis [42] which involves identifying excerpts of data, dividing data into units of code, using and continu-ally adapting the coding frame, building codes into categories ... per-taining to the implementation of PR in people with COPD living in Perth, WA In addition to clinical influ-ence, the financial influence of strategies which seek to optimise the implementation of

Ngày tải lên: 06/05/2021, 15:32

... Immunology of asthma and chronic obstructive pulmonary disease Nature Reviews Immunology 2008;8:183 –92. 22 Vlahos R, Bozinovski S Role of alveolar macrophages in chronic obstructive pulmonary ... al The nature of small-airway obstruction in chronic obstructive pulmonary disease NEnglJMed 2004;350: 2645 –53. 4 Hiemstra PS Altered macrophage function in chronic obstructive pulmonary disease ... activation markers in sub-populations of monocytes in severe COPD We evaluated the level of expression of the activation and homing proinflammatory chemokine receptors CCR2 and CCR5 in each of our subject

Ngày tải lên: 23/10/2022, 16:41

... result in waxing and waning of airway inflamma-tion [13,29-31] This study was limited to cross-secinflamma-tional analysis, with lower airway bacterial colonisation defined as being a single positive ... and the airway inflammatory response Increasing qPCR total bacterial load was strongly asso-ciated with an increase in airway but not systemic Table 2 Airway and systemic inflammation in colonised* ... 1% of bacteria can be cultured using traditional methods [14], there has been increasing interest in the use of culture-independent diagnostic techniques Many of these rely on the analysis of

Ngày tải lên: 02/11/2022, 11:37

... treat-ment comparisons of interest Role of the funding source The funder of the study was involved in study design, data collection, data analysis, data interpretation and writing of the report All ... baseline in inspiratory capacity (IC) and change in morning pre-dose trough FEV1and IC An ex-ploratory endpoint included change from baseline in FVC These endpoints provided additional information ... and B In Part A, the PK profiles of glycopyrrolate and formoterol after chronic administration of GFF MDI were compared with those after chronic administration of the monocomponent MDIs In Part

Ngày tải lên: 15/03/2023, 20:11

... decrease of 9.8% per decline of 6.2μg/ m3, assuming linearity of the association Other studies investigated the effect of declining air pollution in cross sectional studies: Studies in children ... the effect of a reduction in air pollutants on chronic respiratory symptoms and diseases, including chronic cough Chronic cough is common in people aged 70 and over and the prevalence increases ... symptom in the develop-ment of chronic obstructive pulmonary disease [21,22] There is evidence that a reduction in air pollutants attenuates the decline in respiratory health in children The delay in

Ngày tải lên: 17/02/2014, 22:20

... Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study Am J Respir Crit Care Med Inspiratory muscle training in pulmonary ... awareness of the burden of chronic respiratory diseases in all countries of the world, and to disseminate and implement recommendations from international guidelines van Weel C Chronic diseases in general ... RodriguezRoisin R Ventilationperfusion mismatching in chronic obstructive pulmonary disease during ventilator weaning Am Rev Respir Dis M Randomised controlled trial of home based care of patients with chronic

Ngày tải lên: 21/02/2014, 12:20

... reproduction in Trang 2in worsening airway physiology, ultimately manifestingas respiratory and systemic symptoms [10,11] The pre-sence of bacteria in the airways in stable COPD, long thought to be innocuous, ... primary definition of exacerbation was an extended definition added before unblinding to maximize clinically relevant events This definition included any confirmed acute exacerbation of chronic ... to an excess of gas-trointestinal disorders The most common adverse events (occurring in≥ 2 patients) leading to premature discontinuation of treatment, included nausea (moxiflox-acin 5 vs placebo

Ngày tải lên: 12/08/2014, 11:20

... active. These findings contribute to the growing body of information that supports the importance of investigating t he role of IL-17 and related cytokines in COPD, potentially providing novel therapeutic ... 7 of 10 Figure 4 Double immunofluorescence staining for detection of IL-17A and IL-17F expression in CD4 + and CD8 + T cells in airways of COPD patients. (A) Double immunofluorescence staining ... number of positive cells/mm 2 .The number of cells was corrected for the total number of cells by c ounting the number of nuclei in the submu- cosa. The positive staining area of IL-17F in airway

Ngày tải lên: 12/08/2014, 13:22

... level of airway obstruction in COPD, suggesting that cumulative smoking induces chronic inflammation with subsequent sequelae of airway obstruction Our results indicate that inflammatory effects of ... peripheral airways), which may be insufficient to obtain a full view Fourth, remodelling in COPD may itself generate and maintain an inflammatory process, independent of cigarette smoking [25] In order ... inflammatory effects of current smoking may mask findings of chronic inflammation in COPD, since numbers of inflammatory cells in bronchial biopsies and sputum are comparable in smokers with mild COPD...

Ngày tải lên: 12/08/2014, 18:21

... nitrate in a proportion of 1:2 to obtain the final working solution for staining of AgNORs The silver reaction carried out for 22–24 in the dark The sections were mounted in DPX without conterstain ... of allergic obstructive airway diseases such as allergic bronchial asthma [20], not exist In this respect, in striking contrast to numerous existing experimental approaches to determine the inflammation ... compounds in the background of airway inflammation and hypersecretion in future Five different concentrations of SO2 were used in two periods Routine histopathology revealed signs of bronchitis with increas-...

Ngày tải lên: 20/06/2014, 00:20