... Page 4 of 10 loading standard (data not shown). Figure 4A and 4B show that CRP particularly increased in AFL rats com- pared to all other groups including normal rats and rats with NAFL disease ... diagnose early alcohol-induced pathophysiological altera- tions in clinical practice. Materials and methods Animal model and sample preparation Animal experime ntation was pe rformed according to approved ... of the animal models, several indicators in the serum including aspartate aminotransferase (AST), alanine aminotransfer- ase (ALT), total bilirubin (TBIL), total cholesterol (TCHO) and triglyceride
Ngày tải lên: 10/08/2014, 10:20
... 5'-CGATCGGAAGGGATAGACAA-3' LPA5 Forward: 5'-GCTCCAGTGCCCTGACTATC-3' Reverse: 5'-CAGAGCGTTGAGAGGGAGAC-3' COX-2 Forward: 5'-CCCCCACAGTCAAAGACACT-3' Reverse: 5'-GGCACCAGACCAAAGACTTC-3' Page of 12 (page ... fibrosis [29] Intratracheal administration of LPA increased eosinophil influx in guinea pigs [22] and treatment of human eosinophils with LPA induced calcium mobilization, actin reorganization, and ... LPA and LPA2 play a critical role in pathogenesis of airway inflammatory diseases Therapeutic targeting of LPA2 may be beneficial in reducing allergic inflammatory responses in airway diseases
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model" pptx
... detection of antibodies to the antigen in human sera Proc Natl Acad Sci... Nishikawa K, Nishitsuji H, Kurihara K, Hasegawa A, Furuta RA, Fujisawa J, Tanaka Y, Hanabuchi S, Harashima N, Masuda T, ... Sapporo, 060-0815, Japan Email: Takashi Ohashi* - ohashi-t@igm.hokudai.ac.jp; Mika Nagai - purefood@igm.hokudai.ac.jp; Hiroyuki Okada - hiro1230@igm.hokudai.ac.jp; Ryo Takayanagi - coffea-arabica@igm.hokudai.ac.jp; ... of Japan 19 References 1 2 3 4 5 6 7 Hinuma Y, Nagata K, Hanaoka M, Nakai M, Matsumoto T, Kinoshita KI, Shirakawa S, Miyoshi I: Adult T-cell leukemia: antigen in an ATL cell line and
Ngày tải lên: 13/08/2014, 05:21
Therapeutic potential of endothelial progenitor cells in a rat model of epilepsy: Role of autophagy
... Trang 1Original articleTherapeutic potential of endothelial progenitor cells in a rat model of epilepsy: Role of autophagy Shimaa O Alia,⇑, Nancy N Shahina, Marwa M Safarb,c, Sherine M Rizka a ... determination of GABA (EIAab Ltd., Wuhan, China), glutamate (MyBioSource, San Diego, USA), serotonin (LifeSpan BioSciences, Inc Seattle, WA, USA), dopamine (Cusabio, Wuhan, China) and acetylcholine ... epilepsy and are considered a model of drug-resistant epilepsy[15] Material and methods Animals Male Wistar albino rats weighing 170 ± 30 g, obtained from the animal facility of the Faculty of Pharmacy,
Ngày tải lên: 16/01/2020, 00:56
Masters thesis of science intestinal permeability and functional properties of duodenal enteric neurons in a mouse model of autism
... reserves are exhausted, the gastrointestinal lining becomes more susceptible to injury (Rao and Samak, 2012a) Additionally, L-glutamine aids in the elimination of ammonia and in maintaining a healthy ... zonulin-2, claudin-8, and zonulin-581, as well as increased claudin-15 expression, was observed in offspring of a maternal inflammatory activation mouse model of autism, similar to findings in patient ... treatments available (Rao and Bhagatwala, 2019) Trang 151.2 The gastrointestinal tract The major aims of this dissertation are to assess for changes in gut function by analysing permeability in a mouse
Ngày tải lên: 05/02/2023, 12:29
Topological determinants of self sustained activity in a simple model of excitable dynamics on graphs
... to appear in the first layer and be involved in cycling excitation, the signal amplification is already working, due to a hole located in a deeper layer and having a degree k max > k max,1 Indeed ... The data are obtained by scanning graphs having a fixed number N = 80 of nodes and a varying number M = 150 2000 of edges (steps of 30), considering 50 realizations for each value of M, and ... (and in particular can lead to an amplification of excitations in a graph) The gradual change of signal propagation with noise intensity is not related to the sharp, topologically determined transition
Ngày tải lên: 19/03/2023, 15:06
Accuracy of cause of death data routinely recorded in a population-based cancer registry: Impact on cause-specific survival and validation using the Geneva cancer registry
... cause of death, age at diagnosis, age at death, year of diagnosis, year of death, social class, stage of the tumour, treatment, sector of care and place of death The Geneva Cancer Registry has general ... stratified the analysis accord-ing to age at diagnosis, age at death, period of diagnosis, period of death, social class, stage, treatment received, sector of care and place of death Age at diagnosis ... organisation collecting death cer-tificates and maintaining a mortality database for the whole of Switzerland provides the Geneva Cancer Regis-try with a mortality database for the Geneva canton
Ngày tải lên: 05/11/2020, 01:50
demonstration of synchronised scanning lidar measurements of 2d velocity fields in a boundary layer wind tunnel
... data recorded at 2500 Hz has been averaged to match the Lidar measurement frequency of 390 Hz Subsequently, the data of both devices was averaged to 1 Hz and compared again In table 1 the mean ... height containing the wake of all three wind turbines Note that at the far end of the scan, the Lidar units are measuring at a focus distance of about 20 m, which results in a probe length of about ... measurements and a Leica total station in combination with well localised rotating hard targets that give a distinct Doppler Lidar return signature Additional verification of the measurement locations was
Ngày tải lên: 24/11/2022, 17:46
Development of second mode instability in a mach 6 flat plate boundary layer with two dimensional roughness
... and transitional hypersonic boundary layersbecause of the Saffman force29caused by the large shear stress near the wall The laminar and tran-sitional hypersonic boundary layers also do not have ... still faces many other challenges in hypersonic boundary layermeasurement, such as large movement of the tracer particles, large velocity gradient in the thinboundary layer, and intense scattering ... conditioner A DH5939 data acquisition sys-tem is used for data acquisition It has a bandwidth of 600 kHz and a 14-bits vertical resolution.The sampling rate is 5 MHz The detailed parameters of the
Ngày tải lên: 24/11/2022, 17:54
Thành Phần Điện Tử Mạng Gắn Vào Bên Trong Một Mạng Lan Và Hoạt Động Ở Tầng Vật Lý (Physical Layer) Và Tầng Liên Kết Dữ Liệu (Data Link Layer) Của Mô Hình Osi.docx
... ứng với physicallayer & Data link layer trong OSI + Internetwork layer: định tuyến gói dữ liệu giữa các máy chủ + Host to host layer: kết nối các thành phần mạng + Application layer: hỗ trợ ... quốc tế) Physical layer: X21, X21 bis Data link layer: LAP-B Network layer: X25 - TCP/IP (Transmission Control Protocol/Internet protocol): là họ cácgiao thức cùng làm việc với nhau để cung cấp ... 2.5.2 Giao thức tầng mạng * Giao thức X25 là họ giao thức 3 tầng của mạng chuyển mạch gói(Packet Switched Network) Physical layer: X25.1 tớng ứng X21 bit Data link layer: X25.2 tơng ứng với LAP-B
Ngày tải lên: 19/06/2023, 11:23
Optimum feeding rate of solid hazardous waste in a cement kiln burner
... feed rate at 2.5 t/hr, the raw meal feeding was again increased by 5 t/hr (i.e a total raw meal feeding rate of 221 t/hr) A slight decrease in free lime could be observed, indicating that a reduction ... mechanical sieving using a Retsch AS200 instrument Additional chemical analyses of the fuels were available from the plant laboratory 100 mm Trang 33 Full-scale test A full-scale test was carried ... Process data (fuel and raw meal feed rates, emissions, Pfister feeder characteristics, bypass and cooler data, etc) were collected through a plant database system in one minute intervals during the
Ngày tải lên: 05/09/2013, 15:28
A computational study to investigate the effects of insulation and EGR in a diesel engine
... Kingdom of Saudi Arabia 2 Department of Mechanical Engineering, K.L University Vaddeswaram, Guntur(Dist), Andhra Pradesh -522502, India 3 Shaaz College of Engg & Tech Himayatnagar, Moinabad ... cases are the same Also at adiabatic case for 400°CA and 420°CA, these regions more spread out in the main chamber and the values of local peak temperature in cylinder are higher than those of ... curve that for the adiabatic case values of peak temperature increase by 230 k and consequently causes that the amount of NOx emission increases In part load case maximum temperature for adiabatic
Ngày tải lên: 05/09/2013, 16:11
LORD NEUBERGER OF ABBOTSBURY, MASTER OF THE ROLLS JUSTICE IN A TIME OF ECONOMIC CRISIS AND IN THE AGE OF THE INTERNET ppt
... not only essential that we maintain ourselves as a liberal democratic society as an aim in itself, but, by doing so, we will ensure that we can maintain our security and freedom Any reform must ... dislocating revolution And the present pressures on government finances mean that it is particularly important to bear in mind fundamental principles, because they must always be upheld 6 In facing ... development, of international law, international relations and the nation-state He said this, ‘It is a cliché that generals prepare to fight the last war rather than the next one, But if it is a cliché,
Ngày tải lên: 31/03/2014, 03:20
Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt
... Transplantation Seven days after the induction of focal cerebral ischemia, animals were anesthetized with an intra-peritoneal injec-tion of 400 mg/kg chloral hydrate (Pharmaceutical Plant of ... host brain In addition to the expres-sion of the class I and II MHC, the activation of caspase III in NSC cultures and brain sections was also assayed Primary antibodies, including anti-nestin (1:150; ... with class I MHC-positivity were evident in the infarcted brain parenchyma of transplanted rats (A-iii and A-iv) A comparable extent of class II MHC was noted in ischemic rats irrespective of any
Ngày tải lên: 18/06/2014, 16:20
báo cáo sinh học:" Factors affecting recruitment and retention of community health workers in a newborn care intervention in Bangladesh" pptx
... care intervention in Bangladesh Syed Moshfiqur Rahman†1, Nabeel Ashraf Ali†1, Larissa Jennings†2, M Habibur R Seraji1,2, Ishtiaq Mannan1,2, Rasheduzzaman Shah1,2, Arif Billah Al-Mahmud1, Sanwarul ... opportunities in the beginning (i.e working as a Family Welfare Assistant or FWA), after a year there was a marked difference between their salary and that of the government FWAs In implementation of the ... available at the end of the article Trang 2and in raising awareness of appropriate maternal andnewborn care practices [12] Implementation of newborn care interventions is relatively complex compared
Ngày tải lên: 18/06/2014, 17:20
Báo cáo sinh học: "Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" pptx
... were obtained from the Cell Bank of the Chinese Academy of Science (Shanghai, China) and maintained in 5% CO2at 37°C in Dulbecco’s minimum essential medium (DMEM) containing 10% fetal bovine serum ... deoxynecleotidyl transferase-mediated dUTP nick-end labeling; ALT: alanine transaminase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Cr: Creatinine. Acknowledgements This work was supported ... were measured at the indicated time points after intratumoral injection with AdCMV(-), AdhTERTHRP, AdCMVmIL-12 alone or in combination Each data point represented the mean tumor volume in that group
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: " Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastase" potx
... estimate the amount and intensity of staining seen in each sample The grading system used was: as: 0: no staining 1: faint staining; 2: small amount or weak staining; 3: moderate staining; 4: abundant ... Alternatively positive stained areas were calculated using Image-Pro Plus soft-ware and expressed as arbitrary units Semi-quantitative analysis of IFNg Areas of interest were identified using a light ... by local laser ablation (LA) may also stimulate host immunity against cancer We investigated local and systemic induction of immune responses after laser ablation in the setting of residual tumor
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: "Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model" potx
... anti-oxidative, and pro-angiogenic effects in pulmonary tissue after IR injury ADMSC Transplantation Ameliorates Inflammation and Oxidative Stress, and Attenuates Apoptosis and Architectural Damage in ... hematoxylin and eosin (H & E) staining, the number of alveolar sacs was determined in a blinded fashion according to our recent study [33] Three lung sections from each rat were analyzed and ... injury, in animals after acute lung IR Additionally, the number of alveolar sacs was signifi-cantly decreased, whereas the crowded score of lung parenchyma was substantially increased in the animals
Ngày tải lên: 18/06/2014, 22:20
Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf
... and vaccination with a whole tumor cell vaccine combined with GM-CSF (a treatment strategy abbreviated as LRAST) Anti-tumor activity to subcutaneous tumor challenge was examined in a prophylactic ... mAb was obtained from Invitrogen For staining of intracellular Foxp3, a FITC-conjugated anti-body and buffers were purchased from eBiosciences (San Diego, CA, USA) and staining was performed according ... presence of GM-CSF at the vaccine site, antigen-presenting cells (APC) are recruited, activated and capable of activating tumor-specific T cells in the vaccine-draining lymph nodes [33,37] A future aim
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson''''s disease" potx
... calcu-lated for striatal and midbrain volumes The striatum was outlined according to anatomical landmarks following the Paxinos atlas[31] To avoid bias in the outline of the substantia nigra ... 2002, 81:1285-1297. 12. Castano A, Herrera AJ, Cano J, Machado A: Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system J Neurochem ... 11C-CFT binding in the striatum and a parallel increase in 11C PK-11195 binding in the control (vehicle) group The increase in 11C PK 11195 binding was absent in COXIB treated animals and in both
Ngày tải lên: 19/06/2014, 22:20
Bạn có muốn tìm thêm với từ khóa: