regulation of cortisol and epinephrine concentrations in plasma

Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors

Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors

... the expression of HIF-1α and MMP-2 (pro-angiogenic factors) and PAI-1 and CXCR2 (pro-metastatic factors), and accordingly, targeting MMP-10 with siRNA in vivo resulted in diminution of xenograft ... series of steps that involve the loss of cell to cell and cell to matrix adhesion, deg-radation of extracellular matrix and induction of angio-genesis A number of protease systems, including the ... immunohistochemical staining Clinical staging was recorded for cervical cancer using International Feder-ation of Gynecology and Obstetrics (Stages 0-IV) and for bladder cancer using TNM staging (Stage I-IV)

Ngày tải lên: 05/11/2020, 00:17

14 14 0
Radon and radium Concentrations in drinkable water supplies of the Thu Duc region in Ho Chi Minh city, Vietnam

Radon and radium Concentrations in drinkable water supplies of the Thu Duc region in Ho Chi Minh city, Vietnam

... values, there is an increase of the mineral surface or increasing stability of inorganic complexes such as chlorides so that the increase in 226Ra mobility along with an increase in mineralisation ... exposed in Thu Duc district and some others The high iron concentrations of groundwater in HCMC and low pH levels of most surveyed wells are the dominant reasons for high concentrations of 226Ra in ... these drinkable sources of water are low health risk from the standpoint of the concentrations of radon (100 Bq.l-1) and radium (0.185 Bq.l-1) in them It was found that none of the radon concentrations

Ngày tải lên: 08/09/2015, 20:16

22 620 0
FUNCTION AND REGULATION OF CALCIUM INDEPENDENT PHOSPHOLIPASE a2 IN THE ATTENUATION OF PAIN IN MICE

FUNCTION AND REGULATION OF CALCIUM INDEPENDENT PHOSPHOLIPASE a2 IN THE ATTENUATION OF PAIN IN MICE

... This increase was blocked by inhibitors to the alpha-1 adrenergic receptors, MAPK/ERK, and sterol regulatory element binding protein (SREBP) Maprotiline and phenylephrine induced binding of SREBP-2 ... Shirai and Ito, 2004) Intrathecal administration of cPLA2 inhibitors significantly reduced cPLA2 activity in spinal homogenates, which suggest the involvement of cPLA2 in spinal processing of nociceptive ... Lysophosphatidic acid is present in high levels in the brain and the highest level of lysophosphatidic acid binding proteins and receptors are found in brain tissue (Das and Hajra, 1989) Lysophosphatidic

Ngày tải lên: 09/09/2015, 08:15

232 397 0
Ontogeny and hormonal regulation of alpha amylase gene expression in seabass larvae, lates calcarifer

Ontogeny and hormonal regulation of alpha amylase gene expression in seabass larvae, lates calcarifer

... element-binding protein (CREB)-binding protein; DBD, DNA-binding domain; HDAC, histone deacetylase; LBD, ligandbinding domain; NCoR, nuclear corepressor; pCAF, p300/CBP-associated factor; RXR, retinoid ... domain (DBD) bind to a GRE in a cooperative manner (Fig.1.5), in which binding of the first molecule enhances binding of the second (Dahlman-Wright, et al., 1991) Studies of the binding of GR DBD ... enzymes of marine 1.1.1 Development of gastrointestinal tract 2 1.2.1.3 Interaction of Cortisol and Thyroid hormone in larval development 12 1.2.2 Molecular mechanisms of cortisol and thyroid

Ngày tải lên: 17/09/2015, 17:20

195 216 0
DSpace at VNU: Measurements of sulfur dioxide, ozone and ammonia concentrations in Asia, Africa, and South America using passive samplers

DSpace at VNU: Measurements of sulfur dioxide, ozone and ammonia concentrations in Asia, Africa, and South America using passive samplers

... con-centrations were o1.0 ppb The high concentrations of SO2at Linan,China,Elandsfontein,S Africa,Cochin, India,Shang Dian Zhi China,Marcapomacocha,Peru, and Agra,India,reflect major contributions from ... Nam g Department of Chemical and Environmental Engineering, The National University of Singapore, 10 Kent Ridge Cresent, Singapore 119260, Singapore h SEA START RC, Institute of Environmental ... Africa 1 Introduction Measurement programs play a critical role in air pollution and atmospheric chemistry studies Pressures of costs and changing priorities often make it difficult to maintain and

Ngày tải lên: 16/12/2017, 11:11

16 84 0
Transcriptional and post-transcriptional regulation of the jasmonate signalling pathway in response to abiotic and harvesting stress in Hevea brasiliensis

Transcriptional and post-transcriptional regulation of the jasmonate signalling pathway in response to abiotic and harvesting stress in Hevea brasiliensis

... position of the highly conserved domains, Jas and ZIM (TIFY) The Jas domain enables interaction with COI1 and with transcription fac-tors, while the TIFY domains involved in dimerization and in the interaction ... expressed in laticifers [40], the transcripts of HbJAZ1 accumulate in response to tapping and wounding [41], and HbMYC1 and HbMYC2 are more abundant in latex HbMYC1is induced by regular tapping and ... JARs, COIs, JAZs and MYCs that were involved depending on the stress in that signalling Genotypic regulation of genes involved in the JA pathway in response to harvesting stress in mature trees

Ngày tải lên: 27/05/2020, 00:39

17 41 0
Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: Implications for the regulation of tumorigenicity and angiogenesis

Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: Implications for the regulation of tumorigenicity and angiogenesis

... decreased migration of A172 cells (P < 0.001), inhibited A172 tumor-induced migration and invasion of HUVECs (P < 0.001), and significantly inhibited U87 tumor-induced invasion of HUVECs (P < 0.001) ... expression profiling of human glioma U87 and A172 cells overexpressing hHSS1 was performed Ingenuity® iReport™ and Ingenuity Pathway Analysis (IPA) were used to analyze the gene expression in the glioma ... cells in the G0/G1 cell cycle phase, and significantly increased cells in the S and G2/M phases (P < 0.05) U87-overexpressing hHSS1 significantly lost their ability to migrate (P < 0.001) and to invade

Ngày tải lên: 14/10/2020, 13:25

17 35 0
Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer

Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer

... manually using a conventional four-point pathology scoring system (0 - no staining, - weak staining, - moderate staining and - strong staining), and then by an Automated Cellular Imaging System ... play key indispensable role in development PAX proteins are defined by the presence of an 128 amino acid DNA binding domain at their amino terminal end referred to as the, ‘Paired Domain’, which ... genetics of MET/PAX8 and signaling axis Silencing of PAX8 resulted in a significant decrease in not only PAX8 levels but also that of MET and RON expression The functional consequences of loss of PAX8

Ngày tải lên: 05/11/2020, 00:46

12 10 0
function and regulation of auts2 a gene implicated in autism and human evolution

function and regulation of auts2 a gene implicated in autism and human evolution

... sweeps also include genes that are involved in cognition and social interaction, including DYRK1A, NRG3 and CADPS2 [17], reinforcing our interest in AUTS2’s role in cognition and human-Neanderthal ... Anti-proliferating Cell Nuclear Antigen (PCNA) staining showed increased amounts of cell proliferation in morphant fish in the forebrain, midbrain and hindbrain (Figure 2D and Figure S2C– S2E) While seemingly ... expressed in the skeletal muscle and the kidney, and in lower levels in the placenta, lung and leukocytes [4] In the developing mouse, Auts2 is expressed in the forebrain, midbrain, hindbrain, olfactory

Ngày tải lên: 02/11/2022, 10:42

10 3 0
Co activator binding protein PIMT mediates TNF α induced insulin resistance in skeletal muscle via the transcriptional down regulation of MEF2A and GLUT4

Co activator binding protein PIMT mediates TNF α induced insulin resistance in skeletal muscle via the transcriptional down regulation of MEF2A and GLUT4

... and protein levels of GLUT4 and IRS, key molecules in insulin mediated glucose home-ostasis33,38,39 As noted above, chronic elevation of pro-inflammatory cytokines (TNF-α ) is implicated in insulin ... above findings demonstrate that PIMT mediates TNF-α -induced insulin resist-ance in skeletal muscle cells TNF-α induced phosphorylation of PIMT at Ser 298 is required for the inhibition of insulin ... etiology of obesity-induced insulin resistance is complex and several independent studies demon-strate that chronic inflammation is strongly linked to the development and progression of insulin resist-ance15–17,50,51,64

Ngày tải lên: 19/11/2022, 11:40

16 4 0
Differential regulation of starch synthetic gene expression in endosperm between indica and japonica rice cultivars

Differential regulation of starch synthetic gene expression in endosperm between indica and japonica rice cultivars

... regulator of the SSGs in the endosperm, and the expression of all SSGs was upregu-lated in mutant rsr1, resulting in larger grains and higher grain weight and amylose content (Fu and Xue 2010) Alkaline ... consists of two types of glucan polymers: amylose and amylopectin Amylose comprises predominantly linear chains of α(1–4)-linked glucose residues and is synthe-sized by granule-binding starch ... (Hirano and Sano 1998) For tran-scriptional regulation of Wxb, loci du-1 and du-2 might be involved as splicing factors in alternative splicing of pre-mRNA of Wxb(Isshiki et al 2000) The signaling

Ngày tải lên: 24/11/2022, 17:40

10 4 0
Evaluation of cortisol and telomere length measurements in ethnically diverse women with breast cancer using culturally sensitive methods

Evaluation of cortisol and telomere length measurements in ethnically diverse women with breast cancer using culturally sensitive methods

... col-lection of saliva, e.g., they ate a snack after brushing their teeth at bedtime and before collecting their saliva first thing in the morning Thus, clarifying and reinforcing the importance of the ... respectively, and 20 ng of gDNA in a 20-μl final reaction volume The cycling profile for the single-copy gene (S) consisted of denature at 95 °C for 10 min followed by 35 cycles of 15 s at 95 °C, annealing/ ... conducted in English, Spanish, Chinese, or Tagalog and asked about various forms of discrimination, coping, stress, social support and social networks, and quality of life Clinical and follow-up

Ngày tải lên: 24/11/2022, 17:57

12 1 0
Pineal gland transcriptomic profiling reveals the differential regulation of lncRNA and mRNA related to prolificacy in STH sheep with two FecB genotypes

Pineal gland transcriptomic profiling reveals the differential regulation of lncRNA and mRNA related to prolificacy in STH sheep with two FecB genotypes

... Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China Full ... of 18 edges (Fig.8b, of 6 DE lncRNAs and 10 DE mRNAs were involved in the network, and it consists of 10 edges (Fig.8c, total of 30 DE lncRNAs and 12 DE mRNAs were in-volved in the network, and ... roles of these genes mainly involved in regulation of function in pineal gland as candidate genes Co-expression analysis of differential lncRNA-mRNA and functional prediction of target genes revealed

Ngày tải lên: 30/01/2023, 20:12

17 8 0
SIMULTANEOUS DETERMINATION OF BORAX AND POLYPHOSPHATES CONTENT IN FOOD BY LIQUID CHROMATOGRAPHY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (LC-ICP-MS)

SIMULTANEOUS DETERMINATION OF BORAX AND POLYPHOSPHATES CONTENT IN FOOD BY LIQUID CHROMATOGRAPHY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (LC-ICP-MS)

... powder and meat also showed a risk of containing borax of 3/9 pyramidal rice dumpling samples detecting borax content of 54.0 - 444 mg/kg In which, one analyzed sample in total had pyro-P, and tripoly-P ... sanctions, the use of borax in small and individual businesses was still going on at an alarming rate Meanwhile, in contrast, 100% of processed, packaged, and canned products sold by branded manufacturers ... requirements of AOAC standards The research group applied the method in analyzing the content of borax and polyphosphates in a total of 83 samples divided into nine different foods collected in several

Ngày tải lên: 26/04/2024, 21:06

12 2 0
Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"

Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"

... educational institution offering a training program coor-dinated by a medical physician However, this is in its infancy and much needs to be worked out This does indi-cate a growing level of interest in ... investigating include: • What is the incidence and prevalence of musculoskeletal chest pain in chiropractic clinical practice? • What is the incidence and prevalence of musculoskeletal chest pain in ... condition; (4) Inter-professional coordination of care; (5) Best practices and standardization of care; and (6) Training and education These thematic issues are summarized below, and key excerpts

Ngày tải lên: 25/10/2012, 10:06

10 792 0
Improvement of recruitment and selection process in HKT Consultant Jsc

Improvement of recruitment and selection process in HKT Consultant Jsc

... Administration and Human Resources, IT,and Finance and Accounting Now, HKT mainly does business in two fields including implementation of IT and modern management models in business and resesearch ... individual needs and career goals;dentify areas that suffer lack of knowledge and insufficient training, andaccordingly provide methods in the form of workshops and seminars; developingpositive interactions ... betweentraditional administrative functions and the well-being of all employees within anorganization The HRM is responsible for: understanding and relating toemployees as individuals, thus identifying individual

Ngày tải lên: 24/07/2013, 15:36

45 779 8
Integration of energy and environmental systems in wastewater treatment plants

Integration of energy and environmental systems in wastewater treatment plants

... Engineering from North Carolina State University, Master of Engineering in Mechanical Engineering and Master of Business Administration from the University of Hartford, and her doctorate in Engineering ... Department of Engineering Management and Systems Engineering, 600 W, 14th Street, 215 EMGT Building, Rolla, MO-65401, 573-341-7621, U.S.A 2 Department of Engineering Management and Systems Engineering, ... Assistant Professor with the Department of Engineering Management and Systems Engineering, Missouri University of Science and Technology Prior to joining Missouri S&T she was an Assistant Professor

Ngày tải lên: 05/09/2013, 15:28

10 641 1
Tài liệu Environmental impacts of petroleum production: Fate of inorganic and organic chemicals in produced water from the Osage-Skiatook Petroleum Environmental Research sites, Osage County, Oklahoma doc

Tài liệu Environmental impacts of petroleum production: Fate of inorganic and organic chemicals in produced water from the Osage-Skiatook Petroleum Environmental Research sites, Osage County, Oklahoma doc

... production of petroleum typically involves activities such as road building, site clearing and leveling, seismic surveys, and drilling Road building and site clearing impacts the soil and biota, and in ... scarring, soil salinization and oil contamination, and brine and petroleum contamination of ground water and surface water, including Skiatook Lake, a 4,250-hectare reservoir that provides drinking ... isotopes and concentrations of selected inorganic and organic chemicals from surface and ground water samples from OSPER ‘A’ and ‘B’ sites and adjoining areas in Osage County, OK are listed in Table

Ngày tải lên: 14/02/2014, 03:20

30 883 0
Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice

Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice

... 15 of the Economic Zone Edict; Arts and 15 of the Environmental Edict; and Art 11 of the Decree of the Council of Ministers of the USSR, June 1990, ‘On Measures of Securing the Implementation of ... within the inland waters, territorial sea or EEZ adjoining the USSR northern coast and that it includes seaways suitable for guiding vessels in ice Due to the vagueness concerning leading in Article ... the mandatory prescription of leading in ‘other regions’, as well as from Article 7(1) which states that the NSRA will determine the beginning and end of the navigational period taking into account,...

Ngày tải lên: 01/11/2013, 09:20

23 557 0
Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

... contains an N-terminal domain harboring activation function 1, a central DNA-binding domain (DBD) and a C-terminal ligandbinding domain (LBD) containing activation function [67–70] Upon binding androgens, ... Actin and ABPs in transcription regulation B Zheng et al Table Role of nuclear actin-binding proteins interacting with the androgen receptor AR, androgen receptor; LBD, ligand-binding domain ... Direct a-actinin-2 ()) Bundling proteins Coactivator Supervillin NLS F-actin- and membraneassociated scaffolding protein Filamin NLS? Cross-linking proteins Filamin A NLS? Cross-linking proteins Transgelin...

Ngày tải lên: 07/03/2014, 01:20

17 584 0
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