recent advances in vector design

... effective inhibitors of jack bean urease obtained recently[44] It appears to be uncompetitive inhibitor and its binding determined by molecular modeling is dif-ferent than this expected since it ... revealed the mode of binding of this inhibitor In detail, the compound is oriented with its benzopyrone moiety in proxim-ity to urea binding cavproxim-ity, letting phenyl ring to locate at the ... flap contains a cysteine resi-due that could be targeted by inhibitors This cysteine, besides being directly involved in the architecture of the active site, plays a vital role in positioning other

Ngày tải lên: 13/01/2020, 22:09

... carotenoids (Vitamin A, 2007), vitamin D is synthesized in the skin when in direct contact with UVB radiation (Vitamin D, 2007), and vitamin K is made by bacteria living in the intestines when insufficient ... of vitamin A that they were ingesting (Vitamin A, 2007) Not all vitamins need to be ingested in their final form because the body can synthesize some vitamins from other molecules Vitamin A is ... clothing, moving to temperate climates, and the tradition of keeping infants indoors), increased skin pigmentation, reduced in-utero exposure, and reduced capacity to synthesize vitamin D with increasing

Ngày tải lên: 31/03/2014, 22:20

... terpenoids in plant cell cultures Strategies for defining pathways and uncovering rate-influencing steps in global metabolism, and applying this information for successful terpenoid metabolic engineering, ... were evaluated for anti-inflammatory activity by using carrageenin induced hind paw oedema in rats, xylene induced ear odema in mice and cotton pellet induced granuloma in rats It was be concluded ... investigations into the molecular mechanisms of action of garlic compounds are lacking, allicin and ajoene have been investigated in two new in vitro models The first used an apoptosis inducing

Ngày tải lên: 28/05/2014, 15:10

... www.mdpi.com/journal/sensors Review Recent Advances in Nanotechnology Applied to Biosensors Xueqing Zhang, Qin Guo and Daxiang Cui * Department of Bio-Nano Science and Engineering, Key Laboratory for Thin Film and ... while interacting with its target, thereby leading to high binding affinity and sensitive detection GNPs in biosensors can also provide a biocompatible microenvironment for biomolecules, greatly increasing ... used for a multiplexing detection device of various targets In another study, they examined the quantification of the plasmonic binding events and estimation of ligand binding kinetics tethered

Ngày tải lên: 28/05/2014, 15:12

... August, 2011 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Recent Advances in Vibrations ... Trang 1RECENT ADVANCES IN VIBRATIONS ANALYSIS Edited by Natalie Baddour Trang 2Recent Advances in Vibrations Analysis Edited by Natalie Baddour Published by InTech Janeza Trdine 9, 51000 ... the traveling wave incident upon a discontinuity due to geometric or kinetic constraints is described by the local wave reflection and transmission matrices Combining these matrices in a progressive

Ngày tải lên: 19/06/2014, 19:20

... defined in the region xx0 to distinguish it from the one defined in the region x<x0 Combining Eqs (2.35) and (37), one can determine the ampltitude of the wave that rises at the loading point ... )1 0 1( ; )1 1 1 ( ; )1 1 Defining v as the wave injected by the applied load, the difference in amplitudes between the incoming and outgoing waves at the loading point is 2 D 1 D * 2l R * ... amplitudes of incoming and outgoing waves at a point discontinuity When compared to the string problem, the only difference in formulating these matrices for the beam problem is to use vectors and

Ngày tải lên: 19/06/2014, 19:20

... vibration response In this case, a small damping coefficient was included in the model It is noticeable how the nonlinear stiffness deforms the phase space pattern, and instead of producing an ellipse, ... appropriate monitoring system, it can detect early faults in the gear teeth, or damaging effects caused by changes in the operating conditions 3.2 Discontinuous stiffness Stiffness discontinuities are ... A typical ball-bearing system consists of five contact parts: the shaft, the inner ring, the rolling elements, outer ring and the housing The deformation of each part will influence the Trang

Ngày tải lên: 19/06/2014, 19:20

... Trang 1integrals which represent weighted averages of contributions of the strain of all points in the body to the stress at the given point Eringen showed that it is possible to represent the integral ... respectively Using the Hamilton’s principle, the nonlocal bending governing equations of motion for a single layered nano-plate are obtained as follows (Pradhan and Phadikar, 2009a) 2 2 In above equations, ... sections originally perpendicular to the longitudinal plane of the plate remain plane, but not necessarily perpendicular to the longitudinal plane This theory accounts for shear strains in the thickness

Ngày tải lên: 19/06/2014, 19:20

... index p as shown in Table 5 It is clearly visible that the frequency decreases with the increasing grading index, caused by the stiffness decreasing with increasing grading index For the same ... of grading index P , the natural frequency increases with increasing mode The effect of grading index can be shown by comparing the frequency value for the fixed value of mode and changing the ... frequency in rectangular (b=2a) SUS 304/Si3N4, FG plates The effect of grading index can be shown by comparing the frequency for the same value of mode and considering different values of grading index

Ngày tải lên: 19/06/2014, 19:20

... showing the trend of the values obtained in the four weeks of the first test for points 2, 3, 5 and 7. [...]... loss of winding clamping pressure, will lead to insulation 108 6 Recent Advances ... mechanical deformations in the winding, and hence, a change in the vibrational signature of the transformer Typical failures occurring at... Indicator 1 06 4 Recent Advances in Vibrations ... fans and oil circulating pumps for the cooling function • Bushings as an insulating structure, for connection of windings to the outside • Oil temperature indicators • Oil Level Indicator... vibrational

Ngày tải lên: 19/06/2014, 19:20

... 90%, in core vibrations and temperature 100%, 110% in core vibrations Current Effect of current in Effect of current and 30%, 60%, 100%, 120% winding package vibrations temperature in winding ... on propagating the effects of the known variables through the links, and combining them in each unknown variable This can be done by local operations and a message passing mechanism, in a time ... winding Thus, they subtract the effect of both minus the effect of the core to deduce the effects of the winding With this information, they calculate four coefficients that reflect the clamping

Ngày tải lên: 19/06/2014, 19:20

... going into the eclipse, the exposures are changed to 1/16 to take good images in the umbra in each case In cases 5 to 9, measurements start 2 minutes after entering the eclipse, and finish 2 minutes ... Determining the threshold for finding markers The thresholds for finding markers change depending on the luminance of the marker candidate area in the upgraded algorithm, since this changes around ... distinguished as noise if the thresholds for finding markers are changed Trang 54.3.4 Specifying the marker candidate area in the next frame The marker candidate area in the next frame is distinguished

Ngày tải lên: 19/06/2014, 19:20

... October, 2011 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Recent Advances in Robust Control ... expense of chattering in the control variable It is shown in Chapter that combining quantitative feedback theory and sliding mode control can alleviate this phenomenon An integral sliding mode controller ... computing and self-organizing systems It is outlined how the robust control problem can be represented in an information theoretic setting using entropy A toolbox for the robust fuzzy control using...

Ngày tải lên: 19/06/2014, 08:20

... Bi K j In order to obtain the main results in this chapter, the following lemmas are needed (8) 24 Recent Advances in Robust Control – Novel Approaches and Design Methods Will-be-set-by -IN- TECH ... scientific domain For example, it gained a foothold in Economics in the late 1990 and has seen increasing numbers of Economic applications in the past few years This theory aims to design a controller ... for bounding cross terms used in these methods also bring conservativeness Recently, in order to reduce conservatism, the weighting matrix technique was proposed originally by He and al in (He...

Ngày tải lên: 19/06/2014, 08:20

... here to obtain a fuzzy model from (57) By decomposing the nonlinear term and integring nonlinearities of x2 (t ) into + x1 ( t ) incertainties, then (20) is represented by the following fuzzy model: ... set of indices i for which gi ( k ) is an external input, defining ß as the set of indices i for which y i ( k ) is an internal input or a neuron output, and defining ui ( k ) as the combination ... by solving for xo (t ) in the second equation above by setting xo (t ) to zero using the singular perturbation method (by setting ε = ) By performing this, the following equation is obtained:...

Ngày tải lên: 19/06/2014, 08:20

... control Finish training when the training performance is satisfactory Repeat this nominal layer training process for all the nominal neural networks Training the regional neural networks The input ... combining challenge arising from the following: • The designed controller is expected to stabilize the system in the presence of uncertainties in the parameters of the nonlinear systems in question ... aims at developing an 92 Recent Advances in Robust Control – Novel Approaches and Design Methods intelligent control design framework to guide the controller design for uncertain, nonlinear systems...

Ngày tải lên: 19/06/2014, 08:20

... S ( t ) = in a finite time less than or equal to S ( t ) η In other words, by maintain the condition in equation (11), S ( t ) will approaches the sliding surface S ( t ) = in a finite time, ... Proportional Integral Derivative (PID) controllers have been widely used in industry due to their simple control structure, ease of design, and inexpensive cost (Ang, 116 Recent Advances in Robust ... the time varying property of uncertain parameters of the nonlinear systems All these pieces 112 Recent Advances in Robust Control – Novel Approaches and Design Methods come together in an organized...

Ngày tải lên: 19/06/2014, 08:20

... measure within bound In short, the implementation of integral sliding-mode control solves the in uence of matched-type nonlinearities and uncertainties while, in the meantime, maintaining the system ... nonlinearities h( x ) ∈ R m is continuous in x gi ( x, t) ∈ R n , an unmatched-type nonlinearity, possibly time-varying, is piecewise continuous in t and continuous in x We assume the following: ... problem herein Sliding mode control preliminaries In sliding mode control, a time varying surface of S(t) is defined with the use of a desired vector, Xd, and the name is given as the sliding surface...

Ngày tải lên: 19/06/2014, 08:20

... are continuous The four case sliding surfaces are shown in fig 15, those are continuous also The three case continuously implemented control inputs instead of the discontinuous input in Fig 12 ... Continuous approximation of output feedback discontinuous control input Also, the control input (50) with (35) chatters from the beginning without reaching phase The chattering of the discontinuous ... the sliding surface is exactly defined from a given initial condition to the origin, so there is no reaching phase, only the sliding exists from the initial condition The one of the two main problems...

Ngày tải lên: 19/06/2014, 08:20

... clearance of the Recent Advances in Immunology to Target Cancer, Inflammation and Infections carcinogenic HPV infection, pointing to the importance of these factors in future study design In fact, they ... cytokines tended to be correlated with EOTAXIN in women with carcinogenic HPV, while Recent Advances in Immunology to Target Cancer, Inflammation and Infections they were correlated with IL-2 in ... western blots may not work for staining since staining requires fixation, which can change the confirmation of the cytokine protein, thereby preventing antibody binding (Sachdeva and Asthana 2007)...

Ngày tải lên: 07/03/2014, 20:20