progress—are we there yet

... lengthy incubation periods However, synthetic prions were not able to transmit disease directly to wild type mice To obtain infectivity in wild type mice, synthetic prions were Int J Med Sci 2008, ... propagation have been studied However, we are still far away from the complete understading of the mechanistic details of the process despite the efforts reviewed in this article On the basis ... serial PMCA products were inoculated, animals succumbed to disease It appears that infectivity of serial PMCA was due to newly synthesized PrPSc since the original PrPSc seeds were diluted beyond...

Ngày tải lên: 03/11/2012, 11:52

... persevere in good research while seeking new approaches from unheard voices AIDS at 26, are we there yet? Not quite Acknowledgements I thank Ben Berkhout, Mark Wainberg, and Andrew Lever for critical ... women [6] In sub-Saharan Africa, women between the ages of 15–24 are three times more likely than men to become infected with HIV Our failure to empower women to protect them against HIV/ AIDS ... Leadership The theme of this 20th World AIDS Day is "leadership" This is a day to consider how we can exercise leadership on new innovations and vision With increased globalization, today's world...

Ngày tải lên: 13/08/2014, 05:22

... United States and Thailand showed no protection against HIV-1 [20] The failure of traditional approaches asks for exploring novel vaccine strategies against this virus However, neutralizing monoclonal ... following the exposure appears to be contained by a partial antiviral immune response, which is not yet fully characterized Despite this initial immune response, HIV continues to replicate persistently ... distinct regions of the globe: for example, clade B viruses cause AIDS epidemic predominantly in the Western Hemisphere, clade C viruses in the sub-Saharan Africa and clade B, C and E in Asian countries...

Ngày tải lên: 20/06/2014, 01:20

... bread Yes, there are three carrots / Yes, there is a bunch of carrots No, there aren’t any No, there aren’t any Yes, there is a plate of fish Yes, there are two pieces of cheese Yes, there is a ... FISH SWEET CORN CARROT CHEESE GRAPES APPLE LEMON BREAD OLIVES • Answer the questions Use the following words when necessary: PLATE, BUNCH, PIECE, JAR, and LOAF No, there aren’t any Yes, there ... plate of fish Yes, there are two pieces of cheese Yes, there is a jar of olives No, there aren’t any 10 Yes, there is a bunch of grapes ...

Ngày tải lên: 29/08/2016, 07:17

... dịch sang tiếng Việt: Are we doctors? - No, you are not Are you nurses? - Yes, we are Are we armymen? - No, you are not Are you policemen? - Yes, we are Are they flowers? - No, they are not Are ... we ? - , you are not - Are you ? - , we are - Are they ? - , they are not - Are we ? - , you are - Are you ? - , we are not - Are they ? - , they are - Are ... Are we ? Chúng tớ phải không? Chúng phải không? Chúng ta phải không? Are we pupils? Chúng ta học sinh phải không? Are you ? Các bạn ...

Ngày tải lên: 21/01/2014, 15:20

... writers Film Employment As we saw above, overall film employment was relatively stable between 1999 and 2005, decreasing by about percent Among minority film writers, however, there was a notable redistribution ... for the moment, the longer-term trend toward increased industry consolidation Between reports, however, there were a few important shifts among larger independents Larger independents are media ... conglomerates populated the industry landscape Among the larger independents, however, there were a few changes (see Table 15) CarseyWerner, which made the list of larger independents in 2004, closed its...

Ngày tải lên: 19/02/2014, 10:20

... Adoption • High MMR, NMR & U5MR - weak health system & low coverage of MNCH interventions • The mother, newborn and child are inseparable Triad • > 61% of newborn deaths between day and • Maternal deaths, ... issues well captures and binding on all successive state governors) • IMNCH: Launched since 2007 and adopted by NCH • Passage of the national Health Bill – NHIS – PHC Board Achievements/Where Are We ... problems accessing in health care Other Challenges • Weak National human resource development and management • Poor functioning health system with weak referral linkages especially for obstetrics...

Ngày tải lên: 08/03/2014, 15:20

Ngày tải lên: 14/03/2014, 22:20

... of Nelson’s question, whether we are being theoretical yet, a question he posed by turning around Carolyn Porter’s question of 1988, whether we are being historical yet With her query she addressed ... Conclusion: Are We Still Being Historical? Exposing the Ehenheim Epitaph Using History and Theory In 1988 Carolyn Porter answered her question “Are we [literary historians] being historical yet? ” with ... the work involving infinite numbers of viewers, viewings, and meanings If we broaden our scope to include concepts, terms, and structural paradigms that were invented to show the relationship of...

Ngày tải lên: 16/03/2014, 14:20

... attention to the strengths and weaknesses of both types of indicators as well as the complementarities between them For the latter question, we distinguish between experts and survey respondents ... dimension of our taxonomy corresponds to varying answers to the question "Whose views we rely on?", that we take up in Section We distinguish between indicators based on the views of various types ... the wealth of the State and its subjects; to enhance, maintain and also safeguard such wealth, as well as the interests of the subjects Despite the long provenance of the concept, there is as yet...

Ngày tải lên: 29/03/2014, 08:20

... Gleick Safeguarding Our Water 38 We drink it, we generate electricity with it, we soak our crops with it And we re stretching our supplies to the breaking point Will we have enough clean water to ... hard time imagining why they did not” choose to continue We would be globally in so much better shape if we knew whether the Higgs were there or not, in trying to map out the future [accelerator] ... is entwined worldwide is produced by turbines spun by the power with the history of the ways we have learned of falling water Yet there is a dark side to this picture: despite our to manipulate...

Ngày tải lên: 12/05/2014, 16:07

... the future web proclaimed by blogs, investors and so-called “social media gurus.” We are the music makers, And we are the dreamers of dreams.” Wiiam Wonka FADS vs THE FUTURE Where are we going? ... around the web, but are they really? Social validation is the primary driver for activity on today’s web Social Validation • We share on Facebook in order to receive comments and likes • We post ... hope of being re-tweeted, which in turn boosts our follower count • We upload to Flickr and look forward to being favorited Quora Gratuitous Hugh Jackman Geo-blah • Every week a new location-based...

Ngày tải lên: 10/06/2014, 09:38

... addition to the greatly increased use of showers by Americans, there are a lot more of us taking showers In 1900 there were only 76 million of us; today we are 295 million And the amount of water ... shower water is to step into the shower, wet yourself, turn off the water, soap yourself, and then rinse the water-sweat-dirt mixture from your beautiful frame Three minutes of running shower ... our water we have no choice but to either change the way we live or treat the problem we have created We are often told that the two certainties in life are death and taxes To that we can add...

Ngày tải lên: 11/06/2014, 15:18

... 2010 12% Keynote Other 9% 7% Prezi 0% 12% 10% 5% 3% Learn what to with PowerPoint, not just how to use it Presentations Viewed and Delivered per year How many presentations you view per year? 47% ... losers since our 2010 survey Usage in Usage in 2010 vs 2011 2010 2011 Let’s compare usage stats between our results in 2010 and 2011 Usage in 2010 vs 2011 2010 Ppt 2007 Usage in 2011 53% 36% Usage ... 90 Respondents gathered through Keep a look out for the brilliant comments received from respondents What software...

Ngày tải lên: 21/07/2014, 11:53

... discuss where these papers were published Which made it into Science or Nature? Which were in the most visible biology journals and which in more specialized journals? Were any in obscure journals ... be: What were the claims and evidence in the papers cited in the review? What constituted a publishable unit in this field, at that time? Is there a substantial difference in quality between papers ... question, then what we ask of reviewers is that they consider this context in writing the review Sure, it’s easy to trash a manuscript missing a paper published online this week or that fails...

Ngày tải lên: 06/08/2014, 18:21

... individually, may have a relatively weak effect; however, they can interact synergistically when expressed together From this observation, it has been theorized that there is incomplete penetrance ... left cerebral hemisphere in schizophrenia However, evidence also supports an increased likelihood that schizophrenic patients are lefthanded [3], as there exists a gene LRRTM1 associated with ... [1] Contributing environmental factors Epidemiologic studies, as well as studies from discordant identical twins, indicate that there are significant environmental risks for schizophrenia which...

Ngày tải lên: 08/08/2014, 23:21

... with the NSAIDs However, there was a numerical excess of MI events in the celecoxib group, regardless of whether patients were concurrently taking aspirin Since the trial was not powered to detect ... non-naproxen NSAIDs that were studied [15] Konstam et al., employees of the manufacturer of rofecoxib, concluded that differences observed between rofecoxib and naproxen were the result of the ... result of the antiplatelet effects of naproxen A large cohort study by Ray et al [16], however, demonstrated that there was no protective effect of naproxen on the risk of coronary heart disease (rate...

Ngày tải lên: 09/08/2014, 01:21

... joints One week later these joints were replaced and synovial tissue exhibited IL-1Ra expression, whereas the joints receiving control cells were IL-1Ra negative No adverse effects were recorded ... facilitate the transmembrane transport of fusion proteins However, this cargo protein cannot mediate intercellular transport of tat fusion proteins between the adenovirally transduced and noninfected cells ... not been described in experimental models of arthritis, and therefore this treatment with CRAds might not be effective in animals However, inducing cell toxicity by introducing the HSV thymidine...

Ngày tải lên: 09/08/2014, 01:24

... contrast, changes of CTX-I were not related to joint damage [14,15] The changes in CTX-II levels, however, were broadly overlapping with baseline values, and were therefore predictive primarily ... observations as well as the CTX-II data were recently confirmed [17], although there was again broad overlap in biomarker levels of patients with and without progression of joint damage Yet none of ... physical function, however, has been poor for most of them This may be due to a variety of reasons First, what we measure in various body fluids may not reflect sufficiently well what is ongoing...

Ngày tải lên: 09/08/2014, 10:23

... Africa; they found that hospital nurses had higher job demands and lower job resources than other categories of nurses and were therefore more at risk of burnout, despite having many tasks in common ... Additional file Similar tasks that were generated by multiple focus groups were merged into a single task, to avoid redundancy in the task bank SMEs then reviewed the edited tasks to ensure that ... content and job title Results showed that primary care is composed of four functions, the largest being service delivery; over one third of primary care tasks, however, were not directly related to...

Ngày tải lên: 11/08/2014, 05:22