product specification files and medical device validation in quality systems

... problem, explains its relevance in the design of single systems and SPLs, and also motivates it with a running example 2.1 Problem Definition In the software design of single systems and SPLs, the ... abstract syntax and its formalization as the basis for IDEs that can help developers in the design of single systems as well as in the domain engineering and the application engineering of SPLs A ... that can help developers in documenting the web of design information and validating software design for single systems and SPLs To guide the tool developers in building such IDEs, I specify...

Ngày tải lên: 01/10/2015, 17:26

... improvements in local care at a rate far higher than routine incidentreporting systems but without requiring substantial investments of additional resources Moreover, the direct involvement of clinicians ... disclosure and analysis Page of (page number not for citation purposes) Many academic centers are increasingly recognizing engagement in quality improvement as a distinct career pathway [15] Involving ... clinicians in the detection of patient safety and quality- of-care problems likely facilitates the crucial next step in any process for detecting adverse events, namely identifying and implementing strategies...

Ngày tải lên: 25/10/2012, 10:06

... each demand site and flow requirement Runoff and infiltration from catchments, assuming no irrigation inflow Inflows and outflows of water for every node and link in the system This includes ... demand based on supply preferences and demand priorities These two software products are capable of simulating operating rules In AQUATOOL, operating rules are fixed and in WEAP they are defined ... demand and those months for which there is no water demand Demand intakes Transmission links (the equivalent of demand intakes in AQUATOOL) are elements that supply water to demand sites A demand...

Ngày tải lên: 05/09/2013, 14:58

... metalinguistic, and extralinguistic knowledge The system is constructed by combining a "closed" system, based only on linguistic knowledge (a lingware written in ARIANE-78), and two "open" systems, ... documents Lingware engineering may be compared with modern software engineering, because it requires the design and implementation of complete programming systems, uses specification tools, and leads ... to "word senses" - Grafting on expert systems Seeing that linguistic expertise is already quite well represented and handled in current ("closed") systems, we are orienting our research towards...

Ngày tải lên: 08/03/2014, 18:20

... Discovery and Data Mining (PAKDD) (Hong Kong, China) WANG, H AND ZANIOLO, C 2000 Using SQL to build new aggregates and extenders for objectrelational systems In Proceedings of 26th International ... Database Systems, Vol 29, No 2, June 2004 Expressing and Optimizing Sequence Queries in Database Systems • 309 WHERE A.PageType ‘p’ AND X.ccount < 100 AND X.first + 20 Minute > X.ClickTime AND ... systems In Proceedings of the 21st ACM SIGACT-SIGMOD-SIGART Symposium on Principles of Database Systems ACM, New York, 1–16 BERRY, M AND LINOFF, M 1996 Data Mining Techniques for Marketing, Sales, and...

Ngày tải lên: 30/03/2014, 22:20

... both adolescents and adults [1-3] and monitoring adult QOL continues to be of interest in the United States [4,5] Monitoring adolescent QOL is also beginning to receive attention in some adolescent ... Robinson PG: Is quality of life determined by expectations or experience? BMJ 2001, 322:1240-1243 Smith KW, Avis NE, Assmann SF: Distinguishing between quality of life and health status in quality ... Although definitions vary, QOL has been defined as "a popular term that conveys an overall sense of well-being, including aspects of happiness and satisfaction with life as a whole "It is broad and subjective...

Ngày tải lên: 20/06/2014, 15:20

... and work status The mBI is a 50-point scale that was applied to quantify impairment in activities of daily living such as grooming, walking, transferring, hygiene and voiding (50 points meaning ... Oliveira-Filho J: Validation of the National Institutes of Health Stroke Scale, Modified Rankin Scale and Barthel Index in Brazil: the role of cultural adaptation and structured interviewing Cerebrovascular ... activities and self-care [17,18] Most (> 50%) stroke patients in our study showed complaints in these same domains Conversely, the CHF group demonstrated significant complaints in mobility and usual...

Ngày tải lên: 20/06/2014, 15:20

... Advances in Signal Processing and its inverse IN is the N × N identity matrix and 0M ×N is the M × N all zero matrix Operators !, · and ÷ denote factorial component-wise vector multiplication and ... [l] and hence Dtot [l] is accurately known, we can obtain Stot [l] as in (12) This is the principle behind the joint compensation scheme in [11, 17] It should be noted that (14) is also valid in ... these lead to ill-conditioning in (45) N p shows that as the number of training symbols is increased, we also have additional tone pairs that can be included in (45), leading to an improved estimation...

Ngày tải lên: 21/06/2014, 08:20

... matrix Λ contains singular values in descending order, the (M −d)×L matrix U and Q×L matrix V consist of left and right singular vectors, respectively U p (V p ) and Ur (Vr ) are the left and right ... estimation is mainly in uenced by the SNR, and the dimension of the matrices Y1 and Y2 Then the sampling period is the key parameter in both the complexity and performance since the main computation ... pulse, and this sampling rate is already above the Nyquist rate in terms of the −10 dB bandwidth To reduce the sampling rate without introducing aliasing, similar to [3], a low-pass filter with bandwidth...

Ngày tải lên: 21/06/2014, 23:20

... filtering, and neural network learning theory and applications He received the Outstanding Youth Award of the Ministry of Electronic Industry and Guanxi Province Outstanding Teacher Award, China, in ... Science and Technology, Chengdu, China, in 1994 and the M.S degree from the Guilin University of Electronic Technology, Guilin, China, in 2002 He received the Ph.D degree in information and communication ... and [P]i, j is the (i, j)th entry of P The main steps in obtaining (12) are outlined in the appendix As vI and τ are integers, the estimation range of the normalized IFO vI is in [0, N − 1] and...

Ngày tải lên: 22/06/2014, 22:20

... generation, and review are important components of systems InSTEDD and GPHIN incorporate human input and review, allowing users to add comments, tags, and ranks during the data-processing phases and ... GPHIN, HealthMap, InSTEDD, MedISys, MiTAP, and Proteus-BIO), and systems collect from both formal members and informal sources (EWRS and GOARN) ProMED-mail is the only system obtaining firsthand ... existing systems could track only the clinical and epidemiological attributes for corona or influenza infections that had already been discovered and defined, but not new strains of viral infections...

Ngày tải lên: 08/04/2015, 17:20

... communication process (Source: Shannon and Weaver, 1949 and Rogers and Kincaid, 1981) Packaging Strategy Feeding Exploring Evaluating and Transferring Embedding Making Back Adapting Table 2.5, Technology ... of a mechanism, as defined by O’Dell and Grayson (1998), is benchmarking Benchmarking is a process of defining, understanding and adapting outstanding practices either internally or externally ... management systems standards, as well as the customers Overall, specific quality systems like ISO9000:2000 present a formal system used in today’s manufacturing industry in order to maintain quality systems...

Ngày tải lên: 08/11/2015, 17:24

... educational institution offering a training program coordinated by a medical physician However, this is in its infancy and much needs to be worked out This does indicate a growing level of interest in ... was made that medical training includes developing skills/competencies in referral practices (e.g., standardized referral forms are used in medical academic practice and teaching clinics) Discussion ... education in musculoskeletal chest pain Interestingly, concern was also raised by participants that the current training in medical schools was inadequate, and that in part this was due to instructors...

Ngày tải lên: 25/10/2012, 10:06

... Care Resources (ARCCCR) maintains a database recording information on critical care resources, including the timing of introduction of METs In addition, ANZICS maintains an Adult Patient Database ... does not include hospitals participating in the Medical Emergency Response and Intervention Trial ANZICS-APD, Australian and New Zealand Intensive Care Society Adult Patient Database tals, and tertiary ... timing and extent of the introduction of MET services into ANZ hospitals in relation to relevant publications, (b) to assess the association between MET service introduction and the incidence and...

Ngày tải lên: 25/10/2012, 10:35

... portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution in patients ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks ... (Tegretal and others), clozapine (Clozaril), droperidol (Inapsine and others), gabapentin (Neurontin), haloperidol (Haldol and others), lamotrigine (Lamictal), lithium (Eskalith and others), metformin...

Ngày tải lên: 25/10/2012, 10:51

... functions of proteins in human milk include preventing infection, preventing inflammation, promoting growth, transporting microminerals, catalyzing reactions, and synthesizing nutrients.29 In studies ... exposure and development of infants throughout the first year of life: Influence of passive smoking and nursing on cotinine levels in breast milk and infant’s urine Acta Paediatrica 81:550–557 92 Ando ... Amphetamine † Cocaine Heroin Marijuana Nicotine (smoking) Phencyclidine Irritability, poor sleeping pattern† Cocaine intoxication Tremors, restlessness, vomiting, poor feeding Only one report in literature;...

Ngày tải lên: 05/03/2014, 10:20

... 419, 420, 422 and 428 aa; nine aa in total) were located near the interface of the physiological dimer The Cterminal domain may contain structural features involved in protein–protein interactions ... backbone atoms of Mglu and Bacillus glutaminase induced by ligand binding Displacement values for backbone atoms of the nonliganded and liganded structures are shown The average and SD of these conserved ... of ligand binding is also observed in b-lactamase Toho-1 (PDB 1bza and 1iyq) from E coli Substrate specificity Glutaminase is strictly specific to l-glutamine [1] and distinct from asparaginase...

Ngày tải lên: 06/03/2014, 09:22

... it binds to the calmodulin domain, inducing a con‐ formational change and binding of the proximal M13 peptide sequence The M13 binding results in shortening of the linker, bringing CFP within ... effect of calcium binding to receptors calmodulin or troponin [73] In one construct, the CFP/YFP pairing is separated by a linker containing a calmodulin domain and a calmodulin ligand peptide called ... proteins (FPs) are within a certain distance, which may be induced by a liganddependent conformational change in a linking domain between the two fluorescent pro‐ teins, or by binding of interacting...

Ngày tải lên: 16/03/2014, 12:20

... data management in biomedicine; medical data mining and information retrieval; workflow management and decision support in medicine; classification in bioinformatics; data mining in bioinformatics ... Diseases Introduction Translational bioinformatics is involved in the relation of bioinformatics and clinical medicine Bioinformatics was originated by the outstanding development of information ... responsible for storing the information produced in all cancer stages, beginning with the first medical visit and continuing with diagnosis, treatment and monitoring The information produced in each stage...

Ngày tải lên: 22/03/2014, 22:20