probing the electronic structure of complex systems by arpes

... caused by destabilization of the native state relative to the unfolded state The decrease in the thermodynamic stability of the other less stable variants, all of which were exclusively obtained by ... effectof the mutation K31A/R33S is probably caused by the mutation of Arg33 Generally, changes in the thermodynamic stability by mutations can be caused by effects on the native and/or the unfolded ... studied the effect of the mutations on the thermodynamic and kinetic stability The similarity of the impact on both the thermodynamic and kinetic stabilities suggests a predominant effect on the

Ngày tải lên: 16/03/2014, 18:20

... through analysis of the StP primary structure The results have revealed clearly that Arg234 and Arg242 of the TOWER interface region of StP partially destabilize the dimer structure of the unligated ... elements of rmGP [4] and EcMalP [3] onto the linear sequence of StP and thus measures the extent of conservation of the respective
sites in StP As in other GPs, the catalytic site and the PLP ... about by the mutations is reflected by significant shifts of the Cmvalues for the mutants, relative to that for the wild-type, to higher urea concentrations by
1M or greater The stabilization of

Ngày tải lên: 31/03/2014, 01:20

... on the electronic structures of BNNTs Fig-ure 7a,b,c,d,e shows the PDOS of s and p orbitals of B68 and N35 atoms as well as the summation of these orbitals for the (8,0) BNNT At strain of 0, there ... effect of the interactive forces and is deter-mined by the distance between the atoms In Equation 2, Viis the Voronoi volume of atomi and is constructed by the perpendicular planes bisecting the ... strain in the axial direction of the BNNT is given by  =l −l l z t z o z o ( ) ( ) ( ) (3) where l z t( ) is the length of the BNNT in the axial direction following elongation and lz(o) is the initial

Ngày tải lên: 21/06/2014, 05:20

... elements The use of CaO in organic light-emitting diods (OLED) also showed the extension of lifetime of these devices [13] Despite of great potential for various application of CaO, there was ... core treatment options of Dmol3 to treat the core electrons in the same manner as the valence ones For the purpose of choosing the optimal correlation-exchange functional, the structure optimization ... needs to be accompanied by the third particle, the conducting mechanism of the materials should be related to phonon The Eu impurity bands are 3.7 eV above the top of the valence band and 0.41

Ngày tải lên: 14/12/2017, 15:28

... qualitatively the existence of the IS state of Mn2+, as well as the existence of elongated Jahn–Teller distortions at the B sites in (3)–(7) However, the existence of the LS ground-state of Fig The correlations ... explain the spin state of manganese ions Note that the existence of the LS state of Mn2+ ions in (1) and (2) is related to the Structure Types II and II*, while the existence of the IS state of Mn2+ ... states have the same energy On the right side of the TS, the AFM-LS is more favorable than the AFM-IS, while on the left side of the TS, the AFM-IS is more favorable than the AFM-LS We have the saving

Ngày tải lên: 16/12/2017, 17:21

... the philosophy of acancer cell Together, these problems far exceed the importance of an event like the credit crunch.The debt that the global economy is building up with the environment, or the ... to be dominated by the notion of the perfectly tuned string.’1 The Pythagoreans believed that the entire cosmos (a word coined by Pythagoras)produced a kind of tune, the music of the spheres, which ... being burned by a market fall It is therefore impossible to assign them a fixed and independent demand curve of the sort required by the ‘law of supply anddemand’ The collective effect of the agents

Ngày tải lên: 29/03/2018, 13:59

... concerns the change of cropping of farmers and their strategy to adapt to the change of salinity of water These studies only focus on a subpart of Step 6 of the LUP process They enric the plan ... Anlyzis of the recent land-use plans issues in the Mekong Delta 18 1.3 Research questions 22 1.4 Objectives of the current research 22 1.5 Contribution of the thesis 23 1.6 Structure of the thesis ... in the complexity of the decision-making of farmers, who are the ones who ultimately decide how they will make use of their parcels The decision-making is an individual behavior, influenced by

Ngày tải lên: 11/07/2021, 16:37

... depends on the exponent of a weighted set of statistics (y) The set of statistics represents the predictors that one can put in the model; for example, the number of edges, the number of triangles, ... Further, the fraction (i.e., the number of papers that have at least two authors divided by the total number of published papers) and extent (i.e., the average number of authors per paper) of ... chance Furthermore, the more time researchers are part of the field, the greater the human capital that they acquire This capital comes in the form of research ideas and human connections The longer

Ngày tải lên: 23/10/2022, 15:24

... efciency of transfer is determined both by the orientation of the energy transfer partners and by the distance between them [28] The fact that the efficiency of transfer varies with the 6th-power of the ... expressed as the ratio of the distance ‘r’ separating the donor and the acceptor over the distance resulting in 50% of the maximal efficacy (R0) As indicated by the Forster equation, the efciency of ă ... assessing the effect of ligand-binding on the quaternary structure of the receptors, the possibility that the antibodies could inhibit binding to the receptor also needs to be controlled Finally, the

Ngày tải lên: 16/03/2014, 22:20

... parse tree T , if we denote the set of lexicalized phrase structures in T by C, the set of lexicalized word structures by W, and the set of unknown flat words by F, then the joint probability Pr(T, ... with very complex structures. By (3)–(5), the generation of word structures is exactly the same as that of ordinary phrase struc- tures. Hence the probabilities of these words can be defined in the ... Example of a word with internal structure. ment on the correctness of this structure among na- tive Chinese speakers. So if instead of annotating only word boundaries, we annotate the structures of every

Ngày tải lên: 17/03/2014, 00:20

... the integrity of the cell The goodness of these simplified models was evaluated by using the solutions of the full mechanistic model as the reference standard In most cases that were tested, the ... bold) The heading designates the type of load parameter varied and the range of variation relative to the normal value of the reference state The last four columns show the percentage of the total ... passage of the cell through thin capillaries [17], the ATP demand may increase by a factor of 3–5 The oxi-dative load of erythrocytes may rise by two orders of magnitude in the presence of oxidative

Ngày tải lên: 23/03/2014, 06:20

... occupy the position vacated in the H334A mutant through removal of the imidazole group of the His, thereby effectively replacing the function of the origi-nal side chain in catalysis by the mutant ... upshift by £ 1.0 pH units of the entire pH dependence of phosphoro-lysis by the mutant, whereas the pH rate profile of the wild-type was not influenced by the added imidaz-ole Although these results ... for the hydrogen bond between Nd of His334 and the 6-OH of the glucosyl residue bound at the catalytic subsite in the selective stabilization of the transition state O-6, the ring oxygen, and the

Ngày tải lên: 23/03/2014, 07:20

... Acceleration of the cis–trans isomerization of the peptide results in the collapse of these resonances into a single set of peaks (D) Binding, but not isomerization, of the N-terminal peptide of PPWD1 ... by the model of the crystallographic data, which shows Arg489 pointing into the active site of the isomerase, whereas Lys488 points into the solvent There are chemical shifts on addition of the ... interactions between the backbone nitrogen of Glu485 with the oxygen of Gly551, the side-chain of Glu485 is nestled in a deep pocket of the enzyme (Fig 3B) An oxygen of the c-carboxyl group forms

Ngày tải lên: 23/03/2014, 07:20

... B Fig 1 The topology of Glut1 and alignment of the deduced amino acid sequences of Glut1 and Glut3 (A) The predicted structure of Glut1 [1] The position of the single endogenous site of N-linked ... line [25] The differential distribution of these isoforms seems to be independent of cell type or the amount of protein expressed To clarify the molecular basis for the con-trol of the differential ... N31 contains the first 12 amino acids of the N-terminal tail of Glut1 and, subsequently, amino acids 11–496 of Glut3 The location of the FLAG-tag is indi-cated by hatched areas at the N-terminus

Ngày tải lên: 23/03/2014, 09:20

... following the sequence.) Together with the extended loop, which extends 20 A ˚ from the center of the funnel, they form the base of the b subunit (Fig. 3). The last four resi- dues in the C-terminal ... domain with the active site of the enzyme on one side and the Rieske center on the other side of the sheet (Fig. 3). Covering one side of the sheet are two Fig. 2. Crystal structure of PhnI. Ribbon ... from the interface between the a and b subunits to the catalytic site. The comparison of these structures with other known oxygenases suggests that the broad substrate specificity pre- sented by the

Ngày tải lên: 23/03/2014, 09:21

... structure of the dimeric apo form of TmIDH at 2.2 A ˚ . The R-factor of the refined model was 18.5% (R free 22.4%). The conformation of the TmIDH structure was open and showed a domain rotation of 25– 30° ... into the nature of substrate specificity exhibited... of different domain orientations found in other IDH crystal structures The rotation and the position of the dimer of the ... Super- position of the small domains showed an rmsd of 0.27 A ˚ for the C a -atoms, whereas the rmsd between the large domains was 0.32 A ˚ . The relative difference in the rotation of the large domain

Ngày tải lên: 23/03/2014, 10:21

... to the enzyme. This may indicate that the steric limitation of the enzyme’s binding pocket takes place in the area between the ortho and para positions of the aromatic substrate. On the basis of ... removes the steric hindrance and allows the approach of 2IPA towards the catalytic iron. Residue I248 lies at the entrance of the substrate- binding pocket of the enzyme, leading to the substrate channel. ... [14]. The lack of characterization of the structural determinant of the substrate specificity of the AtdA enzyme has thus limited its development as a biocatalyst for the bioremediation of a wide...

Ngày tải lên: 19/02/2014, 02:20

... A ˚ resolution by the molecular replacement method. The schematic view of the overall structure is shown in Fig. 3A. Theenzymeexistsasadimeroftheabc heterotrimer. There is a noncrystallographic twofold ... cob(II)alamin by X-ray irradiation [59]. Therefore, we believe that the structure reported in this paper is also that of the glycerol dehydrataseÆcob(II)alamin complex. The dihedral angle of the northern ... from a bulk of water by the corrin ring of cobalamin. Figure 4B shows the structure around the enzyme-bound cobalamin. The cobalamin molecule is bound between the a and b subunits in the so-called...

Ngày tải lên: 21/02/2014, 03:20

... [27]. On the basis of the Ping Pong mechanism, the acetylation rate (k 2 )of NAT2 by the acetyl donor is independent of the trans- acetylation rate (k 4 ) of the arylamine substrate. Because the values ... the active site. The more dras- tic mutations, Y190I and Y190A, however, revealed the importance of the phenyl ring of the Tyr side chain on the pH dependence of enzyme acetylation. Both of the ... trunca- tions, the availability of the Tyr190 mutants makes it feasible to conduct cell-based studies of the effects of the stability of the acetylated enzyme intermediate on the N-acetylation of aromatic...

Ngày tải lên: 16/03/2014, 00:20

... HeLa? Chapter Ten: The Other Side of the Tracks 1. Explain the meaning of the idiom the other side of the tracks.” 2. What do the names of the creek and the river suggest about life in Lacks Town? 3. How ... in the development of the field of cell culture, and the industry of selling HeLa cells and other human biological materials. 11. Who profited monetarily from the sale of HeLa cells and other ... her mother and her mother’s cells. The result of their relationship is an illuminating portrait of the enduring legacy of Henrietta’s life, death, and immortality. about the book about the author random...

Ngày tải lên: 13/02/2014, 23:20