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... 6 Principles of Clinical Pharmacology TABLE 1.1 Status of Renal Function in 44 Patients with Digoxin Toxicity a Serum creatinine (mg/dL) No. of patients with CL CR of Percentage of group 50 ... 2.5). Concept of Elimination Half-Life If the rate of drug distribution is rapid compared with rate of drug elimination, the terminal exponential phase of a semilogarithmic plot of drug concentra- tions ... of pharmacokinetic cal- culations required for clinical application are simple algebra, some understanding of calculus is required to fully grasp the principles of pharmacokinetics. Concept of...

Ngày tải lên: 22/03/2014, 23:20

... Second Edition In the 28 years since the first edition of this textbook, significant advances have been made in our understanding of physical chemistry of foods, and in particular of the effects of ... osmotic pressure, c is concentration of solute in gl 21 of solution and M 2 is molecular weight of the solute. One of the many uses of Eq. (89) was determination of molecular weight. In that connection, ... Preservation of Foods 462 A. Introduction 462 B. Properties of Ionizing Radiations 463 C. Dosimetry of Ionizing Radiations 468 D. Chemical Effects of Ionizing Radiations 471 E. Effects of Radiation...

Ngày tải lên: 02/04/2014, 15:05

... Center University of Michigan Ann Arbor, MI 48109-2136 J.A. Martin Department of Orthopaedics University of Iowa College of Medicine Iowa City, IA 52242 Manuela Martins-Green Department of Cell Biology ... Obradovic Department of Chemical Engineering Faculty of Technology and Metallurgy University of Belgrade 11000 Belgrade Serbia Bjorn R. Olsen Department of Developmental Biology Harvard School of Dental ... x0 y0 w2 h1" alt="" PREFACE The third edition of Principles of Tissue Engineering attempts to incorporate the latest advances in the biology and design of tissues and organs and simultaneously...

Ngày tải lên: 29/06/2014, 09:21

... of endocrine and exocrine tissues. The endocrine pancreas occupies less than 5% of the pancreatic tissue mass and is composed of cell clusters called the islets of Langerhans. The islets of ... low levels of insulin, but insulin production subsequently fell to undetectable levels as a result of the loss of expression of key insulin gene transcription factors. A combination of the introduction ... IDENTIFICATION OF INTESTINAL STEM CELLS The maintenance of homeostasis of the intestinal epi- thelium involves an intricate and complex interplay of mul- tiple regulatory mechanisms. It is therefore of...

Ngày tải lên: 29/06/2014, 09:21

... not offer free credit but will give you $1,000 off the list price. If the rate of interest is 10 percent a year, which company is offering the better deal? 13. Recalculate the NPV of the office ... 3.774% expected real rate of return Thus, we could say, “The bank account offers a 10 percent nominal rate of return,” or “It offers a 3.774 percent expected real rate of return.” Note that the ... rate of r will, therefore, grow to e r ϭ (2.718) r by the end of the first year. By the end of t years it will grow to e rt ϭ (2.718) rt . Appendix Table 4 at the end of the book is a table of...

Ngày tải lên: 06/07/2014, 08:20

... Brealey−Meyers: Principles of Corporate Finance, Seventh Edition I. Value 4. The Value of Common Stocks â The McGrawHill Companies, 2003 CHAPTER FOUR 58 THE VALUE OF COMMON STOCKS Brealey−Meyers: Principles ... ϭ DIV 1 ϩ P 1 Ϫ P 0 P 0 CHAPTER 4 The Value of Common Stocks 61 Brealey−Meyers: Principles of Corporate Finance, Seventh Edition I. Value 4. The Value of Common Stocks â The McGrawHill Companies, ... existing stockholders buy none of the new issue, their ownership of the com- pany shrinks to The value of the existing shares should be 83.9 percent of the present value of each dividend paid after...

Ngày tải lên: 06/07/2014, 08:20