prevention and early detection of breast cancer

... disease and as an auxiliary means of cancer detection The results provide evidence that the PBMCs and plasma of patients with breast cancer are biochemically distinct from the PBMCs and plasma of ... for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial BMJ 2014;348. 6 Hooley RJ, Andrejeva L, Scoutt LM Breast cancer screening and ... Breast cancer screening with imaging: recommendations from the Society of Breast Imaging and the ACR on the use of mammography, breast MRI, breast ultrasound, and other technologies for the detection

Ngày tải lên: 30/09/2020, 11:00

... determining cut-off value of TNR in detection of breast cancer b TNR of BSGI distribution in breast malignant and benign disease c Sensitivity of BSGI, US, MMG and MRI for detecting breast cancer d ... fibroglandular densities (25–50 % of breast comprising glandular tissue), heteroge-neously dense (51–75 % of breast comprising glandular tissue), and extremely dense (more than 75 % of breast ... Sensitivity of BSGI, US, MMG and MRI in different traits of breast cancer Trang 7US, MMG and MRI for breast cancer diagnosis, thevalues for BSGI were 80.35 and 83.19 %, respectively, and were slightly

Ngày tải lên: 21/09/2020, 01:57

... the frequency of early-onset and second primary breast cancers Based on a population lifetime risk of breast cancer of 1 in 11 (9%), the difference in relative risk between low PRS and high PRS ... breast cancer Nat Genet 2015; 47(4):373 –80. 17 National Institure for Clinical Excellence (NICE) Familial breast cancer: Classification and care of people at risk of familial breast cancer and ... associated with a family history of breast and/ or related cancers (termed hereditary breast cancer) [2] Hereditary breast cancer is clinically important due to the availability of effective risk management

Ngày tải lên: 06/08/2020, 06:26

... resources and training for cancer screening leading to late detection of cancer So, this intervention was to test screening of breast cancer at primary care level for early detection of breast cancer ... rising incidence of breast cancer in India and more importantly high death rates among breast cancer patients One of the leading causes of high breast cancer deaths is lack of awareness and screening ... preven-tion and early detecpreven-tion breast cancer Fig 4 Percentage of women who are aware of breast cancer screening Fig 5 Percentage of women who have undergone screening of breast cancer and performing

Ngày tải lên: 23/09/2020, 01:21

... cycle of breast, ovarian, prostate, and colon cancer cell lines [18-23] In addition, DIM also induces apoptosis andp21 expression in a p53-independent manner [24-26], and is a low affinity ligand ... percent-age of all gated cells in the sample and represent the average and standard error of triplicate experiments Results Opposing effects of two AhR agonists on ERα-mediated repression of CYP1A1 ... Figure 3 Effects of different concentrations of DIM on AhR and ER α target gene expression mRNA levels of AhR target genes CYP1A1 (A) and CYP1B1 (B) and ER α target genes GREB1 (C) and TFF1 (D) were

Ngày tải lên: 14/10/2020, 13:33

... survival of breast cancer patients This marker should be taken into consideration in the development of new diagnostic and therapeutic program for breast cancer Keywords: Breast cancer, Mammary cancer, ... between the expression of this isoform and the clinicopathologic parameters, including prognosis, of breast cancer patients However, the prognostic value of ALDH1A1 for breast cancer remains controversial ... design of treatment and the as-sessment of the prognosis of patients We will further study the influence of ALDH1A1 expression on differenti-ation, invasion, and metastasis of breast cancer cells

Ngày tải lên: 14/10/2020, 17:19

... respect-ively), and family history of breast cancer was more frequent in cases than controls (60% vs 46%) Specific-ally, 39% of cases and 29% of controls had a first degree relative with breast cancer ... et al: The genomic landscapes of human breast and colorectal cancers Science 2007, 318:1108 –1113. 19 Rakoff-Nahoum S, Medzhitov R: Toll-like receptors and cancer Nat Rev Cancer 2009, 9:57 –63. ... gene and breast cancer risk: a meta-analysis Breast Cancer Res Treat 2011, 127:813 –818. 52 Inoue J, Gohda J, Akiyama T, Semba K: NF-kappaB activation in development and progression of cancer Cancer

Ngày tải lên: 05/11/2020, 06:22

... screening ensures early detection of diabetes and initiation of treatment Our results emphasize the importance of development of interventions to improve early detection and prevention of diabetes ... risk of diabetes diagnosis or treatment and early detection of diabetes The higher possibility of early detection of dia-betes among women attending follow-up screening re-duces their risk of late ... the importance of follow-up screening of women to ensure early detection and initiation of treat-ment for the prevention of late complications caused by diabetes Follow-up screening of these women

Ngày tải lên: 01/11/2022, 08:52

... survival of breast cancer patients This marker should be taken into consideration in the development of new diagnostic and therapeutic program for breast cancer Keywords: Breast cancer, Mammary cancer, ... between the expression of this isoform and the clinicopathologic parameters, including prognosis, of breast cancer patients However, the prognostic value of ALDH1A1 for breast cancer remains controversial ... design of treatment and the as-sessment of the prognosis of patients We will further study the influence of ALDH1A1 expression on differenti-ation, invasion, and metastasis of breast cancer cells

Ngày tải lên: 02/11/2022, 08:55

... 1NEAR-INFRARED AUTOFLUORESCENCE IMAGING AND SPECTROSCOPY FOR EARLY DETECTION OF PRECANCER AND CANCER IN THE COLON SHAO XIAOZHUO A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DIVISION OF BIOENGINEERING ... Overview of Colon Cancer Cancer that develops in the colon and rectum is called colon cancer or colorectal cancer Colon cancer is a common type of malignancy, which has uncontrolled growth of the ... the theory of fluorescence imaging and spectroscopy techniques and then introduces the clinical applications of fluorescence imaging and spectroscopy for detection and diagnosis of cancers in

Ngày tải lên: 10/09/2015, 08:29

... tumour free breast was reached in 24/104 (23.1%) of the patients 3/24 cases of pCR were found in each of quartiles 1 and 2, 6/24 in quartile 3, and 12/24 in quartile 4 (Table4and Fig.3) pCR of quartile ... A R T I C L E Open AccessEarly prediction of pathologic response to neoadjuvant treatment of breast cancer: use of a cell-loss metric based on serum thymidine kinase 1 and tumour volume Bernhard ... treat-ment option for patients with early stage breast cancer (BC) [1–4] The acceptance of NACT in routine treatment is based on long-term follow-up of large cohorts of pa-tients, sub-grouped according

Ngày tải lên: 30/05/2020, 21:40

... improved mi-grating capability and invasion in breast cancer cells by up-regulating the expression of Vimentin and F-actin and reorganizing intermediate filaments and microfilaments Angiogenesis is ... dormant niches of cancer cells Fig 5 Expression of critical dynamic factors in breast cancer cells before and after cryopreservation a Cryopreserved and non-intervened ZR-75-1 and MDA-MB-231 ... expression of protein Ki-67 and P53 Accordingly, the expression of multiple related proteins was the proxy assessment as evidence of the breast can-cer cell phenotypes By IF staining and WB, Ki-67 and

Ngày tải lên: 19/09/2020, 22:05

... pathways for each stage of breast cancer The stage- and breast cancer-specificity of subnetworks were assessed through a new computational approach To identify breast cancer-specific prognostic ... Biology and Poisonings Institute, Tehran, Iran 3 Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran Full list of ... (PC and NC) in stage I, four genes (PC) in stage II, 15 genes (PC and NC) in stage III, and 12 genes (PC and NC) in stage IV The Kaplan-Meier curves and Log-rank P-values of c21orf62, SF3B3, and

Ngày tải lên: 30/01/2023, 20:32

... C, Wang Y, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG): Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year ... communities and receive state of the art breast radiotherapy as an adjunct to mod- ern breast conserving surgery. Conclusions Early stage breast cancer can be treated with breast con- servin g therapy and ... from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer. World Journal of Surgical Oncology 2011

Ngày tải lên: 09/08/2014, 01:24

... expression profiles of miRNAs are informative for the classification of human cancers Based on miRNA-expression profiles, Lu et al [13] reported the classification of 334 leukemia and solid cancers ... especially Ago2 and Dicer, were differentially expressed between ER- and ER+ breast cancer, which may explain the different regulatory effects of microRNAs in these two breast cancer subtypes ... ER+ breast cancer This may suggest higher RISC activities and, therefore, that miRNAs down-regulate target gene expression in ER- breast cancer with higher efficiency Results and discussion and

Ngày tải lên: 09/08/2014, 20:20

... 2008 estimates, breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females, accounting for 23% of the total cancer cases and 14% of the cancer deaths[1] ... chemotherapy and endocrine therapy based on tamoxifen, is employed for most cases of breast cancer The poor prognosis of the patients with advanced stage breast cancer is due mainly to the progression and ... progression and metastasis of the disease after the standard surgical treatment Clearly, a better understanding of the mole-cular mechanisms underlying the progression of breast cancer is needed to

Ngày tải lên: 10/08/2014, 10:21

... vii List of Figures viii List of Abbreviations ix Chapter 1 : Introduction 1 1.1 Breast cancer 1 1.1.1 Incidence of breast cancer 1 1.1.2 Classifications of breast cancer 2 1.2 EMT and MET ... association between level of ERp29 and breast cancer stage/grade To elucidate the role of ERp29 in breast cancer progression, aggressive breast cancer cells - MDA-MB231 and BT549 - were stably ... Introduction 1.1 Breast cancer 1.1.1 Incidence of breast cancer Each year cancer is claiming millions of lives and affecting millions more In developed country it is the leading cause of death and is

Ngày tải lên: 13/10/2015, 15:55

... diagnosed with primary breast cancer and had not re-ceived the histopathological results at the time of assessment Inclusion criteria were: first diagnosis of breast cancer, ab-sence of major psychiatric ... histologically confirmed diagnosis of breast cancer were identified via two databases: the Insti-tutional Breast Cancer Database and the Tumor Registry of the European Institute of Oncology (IEO) The study ... 8avoidance of reality that, in the case of breast cancerpatients, may exclude the cognitive and emotional impact of the disease In particular, low levels of paternal care were associated with the use of

Ngày tải lên: 10/01/2020, 13:42

... cancer is suspected, a microscopic analysis of the breast tissue is required for diagnosis, determination of breast cancer status and type of breast cancer The tissue for microscopic analysis ... % of all breast cancers (10) and even in94 % of TNBCs (11).Due to its characteristic aberrant glycosylation as a result of reduced activity of glycosyltransferases and accelerated activity of ... diagnosis and treatment of breast cancer which could be addressed by utilizing specific molecular targets Tumor-associated MUC1 is expressed on over 90 % of all breast cancer entities and differs

Ngày tải lên: 15/01/2020, 19:03

... mortality from that cancer, and the rationale for the early detection of breast cancer is similar. Fifty years ago, there was no established method for the detection of breast cancer at an early stage ... $40,000 offered, detection of early breast cancer, especially in may be used over 3-year period. the areas of biological or immunological methods for the detection of early- stage breast cancer. New ... de- Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer Committee on Technologies for the Early Detection of Breast Cancer Sharyl J. Nass, I. Craig Henderson, and Joyce...

Ngày tải lên: 05/03/2014, 12:20