planning a randomized controlled trial

... cited. Trang 2The working alliance in a randomized controlled trial comparing online with face-to-face cognitive-behavioral therapy for depression Barbara Preschl1, Andreas Maercker1, Birgit Wagner2§ ... residual gain score and the working alliance ratings in either group Trial registration: ACTRN12611000563965 Background In the past decade, accumulating research has demonstrated that internet-based ... compliance to treatment (Therapist Alliance Questionnaire, TAQ; modified version of the Helping Alliance Questionnaire, HAQ; [28]) In an open trial, Klein and colleagues investigated a therapist-assisted

Ngày tải lên: 11/08/2014, 16:21

... on patient report of col-our of sputum Statistical analysis Continuous demographic variables were analysed using two-way analysis of variance (ANOVA) and categorical demographic variables by a ... efficacy results, the primary population for efficacy analyses was the PP population, as defined in Additional file 4: Statistical analysis Analyses in the intent-to-treat (ITT) population, randomized ... Moraxella catar-rhalis, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus Monitoring of changes in gastrointestinal flora was conducted by collecting rectal swabs from a

Ngày tải lên: 12/08/2014, 11:20

... pulmonary disease patients: a randomized controlled trial: measurement information and supplemental tables ”, contains additional information about the measurements used, and additional information ... for ana-lyses and all available data used for anaana-lyses until patients dropped out A p < 0.05 was considered statisti-cally significant Analyses were performed by an inde-pendent statistician ... for linearity by visual inspection of all plots A full data set analysis was performed, signifying intention-to-treat, with all data of all patients available at the start of the home-based period

Ngày tải lên: 12/08/2014, 14:20

... score, Acute Physiologic and Chronic Health Evaluation (APACHE) II score at admission, arterial blood gases, ventilator settings and cardiovascular measurements were recorded Arterial blood gases, ... higher mean airway pressures than patients on Table 1 Patient characteristics at study entry Diagnosis (%) Site (%) Values are presented as means with standard deviations APACHE II, Acute Physiologic ... better compared with CV OI was evaluated as an interaction term in a Cox Proportional Hazard model with treatment, age and OI as explanatory variables The likelihood ratio test comparing the reduced

Ngày tải lên: 12/08/2014, 22:22

... such as increased extracellular glutamate concentrations, increased intracellular Ca2+, free radical overproduction and exacer-bated inflammatory response Medication targeted at a patho-logical ... decreases brain edema, attenuates free radical damage, and reduces neuronal loss in TBI animal models [8-13] Progesterone also reduces the inflammatory response and attenuates neurological abnormalities ... contributions GMX and WQY participated in the trial design and were involved in the study analysis and summary GMX and WMW obtained the data GMX, JW, ZHL and WMW participated in the data analysis and interpretation

Ngày tải lên: 13/08/2014, 11:22

... design, acquisition of data, analysis and interpretation of data, and writing of the manu-script JALP was responsible for acquisition of data and patient randomization JH acquired data and conducted ... (n) Age, ISS, SAPS II, APACHE II and APACHE III are expressed as median and interquartile range APACHE, Acute Physiology and Chronic Health Evaluation; admission CT, admission computed tomography ... analysis Quantitative variables are expressed as the mean and stand-ard deviation from the mean (SD) in normal distributions, and as median and interquartile range in cases that were not nor-mally

Ngày tải lên: 13/08/2014, 11:22

... in OA-ALI, due to decreased chest wall com-pliance associated with increased abdominal pressure (Table 1) Thus, in HCl-ALI, mean transpulmonary airway pressure (Ptransp, mean) was higher at all ... in OA-induced ALI can be explained by the elevated IAP and, as a consequence, a cranial displace-ment of the diaphragm with compression atelectasis or con-solidation of the juxtadiaphramatic ... Pre-acute lung injury (ALI) (Table S2 in additional data file 1) was tested only against baseline ALI Post hoc testing was always performed if a significant F ratio for a factor or the interaction

Ngày tải lên: 13/08/2014, 11:23

... Medical College, Central Avenue, Nagpur India, 2 Government Medical College, Nagpur, India and 3 Nagpur Municipal Corporation health and Family Center Nagpur, India Email: Archana B Patel* - archana_patel@vsnl.com; ... Patel* - archana_patel@vsnl.com; Leena A Dhande - leenadhande@hotmail.com; Manwar S Rawat - dr_manwarrawat@hotmail.com * Corresponding author zinccoppermicronutrientacute diarrheaand cost-effectiveness ... Medical College, Nagpur, India for assisting in the data collection and data management We are thankful to the patients and their parents for their participation in the trial Finally we thank

Ngày tải lên: 13/08/2014, 13:20

... dysfunction and liver injury, ALAT: alanine aminotransferase; ASAT: asparatate aminotransferase; AVP: arginine vasopressin; CO2: carbon dioxide; dp/dtmax: maximal systolic con-traction; dp/dtmin: maximal ... production, arterial, portal, hepatic, and mixed venous blood gases and oxi-metry), intrathoracic blood volume, extravascular lung water and indocyanine-green plasma disappearance rate (thermal-green ... μg/kg/min) Tables 1 and 2 and Figures 1 and 2 summarize the data on systemic hemodynamics and left heart function (Table 1), as well as O2 exchange, acid-base status, and metabolism (Table 2) AVP-treated

Ngày tải lên: 13/08/2014, 18:22

... 3 mg/kg/day Male Other Asian-Indian Black Other Disseminated candidiasis C albicans, Candida tropicalis, Candida parapsilosis, Candida glabrata versus other Candida spp. Candida parapsilosis ... remained a potential explanatory factor associated with treatment success, mortality at day 8, and mortality at day 30 Trial registration Post hoc analysis - clinicaltrials.gov trial NCT00106288 APACHE: ... 230) Primary diagnosis Isolated Candida spp at baselinea Data presented as n (%) ICU, intensive care unit aA patient may have had more than one Candida spp isolated at baseline. Table 4 Treatment

Ngày tải lên: 13/08/2014, 19:20

... clinical characteristics and courses of disease Materials and methods Design and eligibility This economic evaluation was part of the RELAP trial, a randomized controlled multicenter trial comparing ... (CAPD)-related peritonitis and pancreatitis Specialized randomization software was used to allocate patients centrally, with stratification by study site and APACHE-II classification as a minimization ... [6] Resource utilization and costs Data available for analysis from the index admission and follow-up admissions were available for all patients Additional data on use of healthcare resources outside

Ngày tải lên: 13/08/2014, 20:22

... , James B Fink 3 , John D Santamaria 1 , Duncan J Campbell 4,5 Abstract Introduction: Prolonged mechanical ventilation has the potential to aggravate or initiate pulmonary inflammation and cause ... Yoshikawa T, Tanaka KR, Guze LB: Infection and disseminated intravascular coagulation. Medicine 1971, 50:237-258. 11. Bone RC, Francis PB, Pierce AK: Intravascular coagulation associated with the adult ... (25), day 1 placebo (24) and heparin (25), day 3 placebo (21) and heparin (15), day 5 placebo (19) and heparin (11), and day 7 placebo (13) and heparin (7). Graphs represent mean ± standard error

Ngày tải lên: 13/08/2014, 21:21

... on quality of life in overweight/obese postmenopausal women: a randomized controlled trial International Journal of Behavioral Nutrition and Physical Activity 2011, Ikuyo Imayama (iimayama@fhcrc.org)Catherine ... postmenopausal women: a randomized controlled trial Ikuyo Imayama1, Catherine M Alfano2, Angela Kong3, Karen E Foster-Schubert4, Carolyn E Bain1, Liren Xiao1, Catherine Duggan1, Ching-Yun Wang1,5, ... We performed analyses using last observation carried forward For comparison, we also performed the analyses using available data and using multiple imputation All randomized participants were included

Ngày tải lên: 14/08/2014, 08:21

... model as appropriate All available data were used in the analysis, and no imputation was performed for missing data Trial Registration and Ethics Approval The trial was registered with the Australian ... trials, with 5 trials per panel Panels were illuminated in a random order to eliminate anticipatory movements The average time taken during the 20 trials was used in the analysis Postural Stability. ... using the average absolute constant error between the target and actual angle across 20 trials (5 trials each for inversion, eversion, plantar flexion, and dorsiflexion angle presented in a random

Ngày tải lên: 25/08/2016, 19:20

... Trang 1100 Original Article Assessing the Effectiveness of Teachers’ Mental Health Literacy Training in Cambodia: A Randomized Controlled Trial Bunna Phoeun1,3,*, Amanda J Nguyen2, Dang ... culturally adapted version of a school-based mental health literacy program, initially developed in Canada, for use in Cambodian high schools Specifically, we aimed to adapt the program, evaluate baseline ... reflects poor mental health literacy among teachers [49, 50] Further, research across multiple settings such as United States, Canada, Malaysia and Nigeria have all demonstrated a need to improve

Ngày tải lên: 10/01/2020, 09:01

... for analysis ap-plied are Analysis of variance (ANOVA) as well as Analysis of covariance (ANCOVA) models The main factor is the intervention group (A or B) and the most relevant secondary factor ... Abbreviations ADS: Allgemeine Depressionsskala; ANCOVA: Analysis of covariance; ANOVA: Analysis of variance; BAMF: Bundesamt für Migration und Flüchtlinge (German Federal Office for Migration and ... initial value (baseline value) All baseline characteristics will be described at the individual level Relevant characteristics will be added if Trang 9applicable as covariates to the models Six main

Ngày tải lên: 10/01/2020, 12:22

... Measurement Waves and Informants (DOCX 19 kb) Abbreviations ANCOVA: Analysis of Covariance; CAU: Care as Usual; LGC: Latent Growth Curve; R&W: Rock and Water; RCT: Randomized Controlled Trial ... study is financially supported by a grant from The Netherlands Organization for Health Research and Development, grant number 531001106 Availability of data and materials The datasets obtained in ... there are differences in the amount and sort of physical activities adolescents engage in For instance, Black and Asian adolescents are less physically active and show more sedentary behavior than

Ngày tải lên: 10/01/2020, 12:26

... General Data Protection Regulation Data and hair and saliva samples are coded using a participant numbering system Names and other information that can directly identify participants is omitted Data ... the changing table while being changed and a car parks backwards at a safe distance from a baby in a car seat placed on sidewalk) These videos thus con-trast situations in which protective action ... stairs, a baby accidentally falls off a changing table while being changed, and a car is parked backwards and hits a baby in a car seat which was placed on the parking lot) The threatening videos

Ngày tải lên: 10/01/2020, 12:28

... data Data transformation will be applied when necessary to approach normal distribution of data points [82] To avoid any inflation of Page of 10 statistical tests, we are not planning to examine ... a randomized controlled trial Laura Kolijn1,2,3, Saskia Euser1,2,3, Bianca G van den Bulk1,2,3, Renske Huffmeijer1,2,3, Marinus H van IJzendoorn1,2,3 and Marian J Bakermans-Kranenburg1,2,3* Abstract ... first assessment, from all participants Participants were reminded that participating in the trial is voluntary, that their data are stored anonymously and securely and that they can withdraw from

Ngày tải lên: 10/01/2020, 12:38

... only a few small trials have directly compared CBT and MBCT as two active treatments (Manicavasagar et al., 2012; Zautra et al., 2008) None of them have been conducted in a diabetic population ... & Costa, PTJ (2008). Personality and differential treatment response in major depression: A randomized controlled trial comparing cognitive-behavioural therapy and pharmacotherapy The Canadian ... Analysis plan Primary analyses are conducted according to the intention-to-treat approach To answer the primary research question, repeated measures analyses of (co) variance ((M)AN(C)OVA) are

Ngày tải lên: 10/01/2020, 12:44