operationalizing the biopsychosocial model of disease

... the same viral RNA polymerase; this RI RNA is used as a template for the synthesis of more negative sense genome [11-13] The use of in vivo models with good clinical translation is vital in the ... high titres of neutralising antibody Our data support this hypothesis We conclude that the evaluation of antibodymediated viral therapies in the mouse model may be confounded by the high viral ... out the in vivo and cellular assays and analysis and interpretation of data, EJM, MW and CL participated in the design of the study and analysis and interpretation of data HB conceived of the...

Ngày tải lên: 12/08/2014, 01:22

... selected on the basis of their international expertise in the area of each disease or risk factor of concern The experts were identified either by the WHO unit responsible for the area, by other experts ... estimates of burden of disease from a much broader range of environmental risk factors, and in terms of the categories of diseases and health conditions affected The analysis makes use of the results ... estimates of 'burden of disease' from environmental factors across the major categories of reported diseases and injuries By focusing on the disease endpoint, and how various kinds of diseases...

Ngày tải lên: 12/02/2014, 12:20

Ngày tải lên: 18/02/2014, 11:20

... or required further explanation of the need for their samples I often thought of the irony of the situation At these reunion parties, Dr Garcia would oversee the administration of the electrical ... with the arrowheads representing the short, direct repeats formed at the point of insertion The left half of Alu contains the A and B boxes of the RNA polymerase III promoter The two halves of the ... (3) elucidation of the chemical basis of heredity, the molecular basis of disease has been addressed in the context of how mutations affect the structure, function, or regulation of a gene or its...

Ngày tải lên: 05/03/2014, 23:20

... area; an examination of the effects of day -of -the- week and daily changes in the weather; the use of general additive models with nonparametric smoothing, or general linear models with parametric ... we propose that the log linear model of exposure and the average of all years of available exposure be used, since the resulting estimate of the disease burden is likely to have the minimum measurement ... the attributable disease or potential benefits of reducing the risk factor by a specified amount A determination of the size of the population groups exposed to PM10 and PM2.5, and the type of...

Ngày tải lên: 06/03/2014, 16:20

... disorders Diseases of the nervous system Diseases of the circulatory system Diseases of the respiratory system Diseases of the digestive system Diseases of the skin and subcutaneous tissue Diseases of ... applicable to the superficial tissues of the tongue as well as to other soft tissue surfaces of the oral cavity In many cases, however, there is a separate classification for a set of diseases or ... meeting of consultants was convened by the World Health Organization in 1964 to consider the classification of diseases of the buccal cavity in relation to the impending Eighth (1965) Revision of the...

Ngày tải lên: 15/03/2014, 11:20

... distribution of burden of disease 42 16 Leading causes of burden of disease 42 17 The disease and injury burden for women 46 18 The growing burden of noncommunicable disease 47 19 The unequal burden of ... contribution of various conditions and diseases to the burden of disease in a community are given in later sections Diarrhoeal disease is the most common cause of illness Of the diseases listed ... but is the leading cause of cancer deaths in the African Region and in the low- and middle-income countries of the Region of the Americas In the South-East Asia Region, Global Burden of Disease...

Ngày tải lên: 28/03/2014, 09:20

... uncertainty of the base-case estimates was quantified by estimating the joint uncertainty in the estimates of annual mean concentration and the estimates of the relative risks The sensitivity of the ... absence of essential data on exposure and response Where better data exist, as they currently in some parts of the world, they should of course be used Future estimates of the global burden of disease ... that of unsafe sex (due to acquired immunodeficiency syndrome and other risks) (WHO, 2002) DISCUSSION The results indicate that the impact of outdoor air pollution on the burden of disease in the...

Ngày tải lên: 29/03/2014, 18:20

Ngày tải lên: 24/04/2014, 17:22

... 9) The sizes of the DNA molecules obtained from this model on the replication of LuIII Lt-Lt correspond very closely with the sizes of the products predicted by the model (figure and 3) for the ... interpretation of the data, participated in the idea and design of the models proposed and in the drafting and revision of the manuscript IDM collected the data resulting from the transfections of LuIII ... for the Replication of Parvovirus LuIII Proposed Model for the Replication of Parvovirus LuIII A model for the replication of the (+) and the (-) strand of LuIII is shown The NS1 nick site and...

Ngày tải lên: 19/06/2014, 08:20

... in the formation of retinal NV in the later stages of the OIR model In this study, we investigated the temporal and spatial distribution of microglial cells during the different stages of the ... retina, the mean number of microglial cells Page of from the three fields of each counting position (central or peripheral zone, and layer) was calculated Then, the mean and standard error of these ... expressed under the control of the Cx3cr1 promoter They are located in the vitreous (v) near the retina (see arrow heads in the cryosection) In contrast to the microglial cells, they have a larger...

Ngày tải lên: 19/06/2014, 22:20

... assemble the mesothelin mRNA sequence using the Blast and multiple alignment programs available at NCBI The contour quantities (density of the band multiplied by the area of the band) of amplicon ... dilutions None of the sera from hens without mesothelin mRNA expression had an optical density (OD) above the cutoff value for mesothelin antibody The cutoff was determined as the mean value of normal ... mesothelin (D-F) Mesothelin staining was observed in the ovarian surface epithelium (SE) and clusters of cells in the ovarian stroma (ST) of tumors that express mesothelin (G-I) Examples of different...

Ngày tải lên: 20/06/2014, 08:20

... Dây treo: giá trị lực dọc trục lớn tính theo MH3, nhỏ theo MH1 Giá trị thay đổi khoảng ±1,26% Chuyển vị theo phương thẳng đứng: lớn tính theo MH3, nhỏ theo MH2 Giá trị thay đổi khoảng ±1, 6% ... khoảng ±10% Dầm ngang giữa: giá trị mơ ment dương lớn tính theo MH2, nhỏ theo MH4 Giá trị mơ ment âm lực cắt lớn tính theo MH2, nhỏ theo MH3 Giá trị mơ ment dương thay đổi khoảng từ -64,1% đến ... -13,15% đến 15,15% Giằng ngang: giá trị mơ ment dương lớn tính theo MH2, nhỏ theo MH1 Giá trị mơ ment âm lực cắt lớn tính theo MH2, nhỏ theo MH4 Giá trị mơ ment dương thay đổi khoảng từ ±7,0%, giá...

Ngày tải lên: 08/08/2014, 04:21

... Based on the data presented, we conclude that the TSK mouse is not a suitable model to study the effects of radiation in case of scleroderma Further studies are required to elucidate the role of FBN-1 ... separated by 24 hours Each point for the TGF-β1 protein represents the mean value for the group The error bars represent the standard deviation of the mean Page of (page number not for citation purposes) ... the median value for the group The error bars represent minimum and maximum value of the range Each point for leg extension data represents mean value for the group The error bars represent the...

Ngày tải lên: 09/08/2014, 09:22

... years [21] These include the Theory of Reasoned Action, the Theory of Planned Behavior, the Health Belief Model and Social Cognitive Theory [31-34] Implicit in the combination of these theories ... [21]? The ability of these constructs to predict behavior depends upon how well the behavior is defined and upon the degree of correspondence between the measure of behavior and the measures of the ... could then develop interventions that target these determinants, thereby increasing the likelihood that the intervention would lead to the adoption of the target behavior As noted above, each of the...

Ngày tải lên: 11/08/2014, 05:21

... weight of PCE Most of the solids in the commercial extract were not soluble in 50% ethanol The dry weight of the ethanol-insoluble pellet remaining after centrifugation of the extract from 1.0 g of ... in both ears of each mouse by the topical application of µg TPA dissolved in 20 µL of acetone to both the inner and outer ear surfaces Thirty minutes after the application of TPA, the inner and ... guidelines The sample size of animals for each test group was justified on the basis of a pilot experiment showing that the sample standard deviation (s) for measurements of ear edema was about 5% of the...

Ngày tải lên: 11/08/2014, 08:21

... years [21] These include the Theory of Reasoned Action, the Theory of Planned Behavior, the Health Belief Model and Social Cognitive Theory [31-34] Implicit in the combination of these theories ... [21]? The ability of these constructs to predict behavior depends upon how well the behavior is defined and upon the degree of correspondence between the measure of behavior and the measures of the ... could then develop interventions that target these determinants, thereby increasing the likelihood that the intervention would lead to the adoption of the target behavior As noted above, each of the...

Ngày tải lên: 11/08/2014, 16:20

... distribution of exposure that would lead to the lowest theoretical minimum levels of disease burden Thus, for example, in the case of tobacco, the theoretical minimum distribution would be 100% of the ... assess the reliability of data, and the use of a common metric to summarise disease burden from both diagnostic categories of the International Classification of Disease and Injuries, and the major ... a measure of the future stream of healthy life (i.e years expected to be lived in full health) lost as a result of the incidence of specific diseases and injuries in 1990 The effect of incident...

Ngày tải lên: 11/08/2014, 18:20

... DNA into the muscle of the murine model of allergic disorder Some of the injected DNA might be postulated to stay in the nuclei of cells or be integrated in the host DNA and elicit the endogenous ... weeks after the last vaccination, mice were sensitized subcutaneously at the base of the tail with 100 µg of HDM extract in CFA The mice were also given an intraperitoneal dose of 300 ng of purified ... orchestrating the interaction of the participating cells since they are able to release an array of cytokines that can attract, prime, and activate other cell types [25] A successful outcome of immunotherapy...

Ngày tải lên: 13/08/2014, 13:22