nutritional support of the cancer patient

genome wide methylation profiling of ovarian cancer patient derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways

genome wide methylation profiling of ovarian cancer patient derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways

... epigenetic therapy for cancer [6, 7] Effective treatment of cancer relies on the identification of key molecular targets of cancer growth and subsequent development of therapeutic agents against these ... Groningen 9700 RB, The Netherlands Full list of author information is available at the end of the article © 2016 The Author(s) Open Access This article is distributed under the terms of the Creative ... patients There is growing evidence that HGSOC PDX models not only recapitulate the histology of patients’ tumors but also maintain the heterogeneity of them to some extent [12, 13] However, their

Ngày tải lên: 04/12/2022, 10:31

15 5 0
Ebook Molecular diagnostics for dermatology - Practical applications of molecular testing for the diagnosis and management of the dermatology patient: Part 1

Ebook Molecular diagnostics for dermatology - Practical applications of molecular testing for the diagnosis and management of the dermatology patient: Part 1

... broken by the processes of transcription and transla-tion The end product of these processes is the production of a protein molecule composed of amino acids The amino acid composition of the protein ... other ancillary test, dependent on the prevalence of the disease in the population tested Testing a large number of samples in a population of low disease prevalence will increase the number of ... single reac-tion, we underline the importance of critically evaluating data in the context of the individual patient, often requiring input by the entire care team We offer some practical advice,

Ngày tải lên: 22/01/2020, 03:21

182 70 0
ALI multilayered co-cultures mimic biochemical mechanisms of the cancer cellfibroblast cross-talk involved in NSCLC MultiDrug Resistance

ALI multilayered co-cultures mimic biochemical mechanisms of the cancer cellfibroblast cross-talk involved in NSCLC MultiDrug Resistance

... allows for the administration of lower doses considered the main advantage of the inhalational route and it derives from the direct delivery of the active principle to the site-of-action and the avoidance ... “air-lifted” by removing the medium from the upper chamber of the inserts and exposing the apical surface of the cells to the air This system allows searchers to test the effects of aerosolized particles ... increased patient acceptance The clinical translation of inhaled cancer therapies is currently impaired by the complete lack of preclinical (in vitro or in vivo) models capable of predicting the behaviour

Ngày tải lên: 17/06/2020, 17:35

21 23 0
Prognostic consequences of implementing cancer patient pathways in Denmark: A comparative cohort study of symptomatic cancer patients in primary care

Prognostic consequences of implementing cancer patient pathways in Denmark: A comparative cohort study of symptomatic cancer patients in primary care

... admission date) If the patient was diagnosed by a private practicing specialist, the date of diagnosis corresponds to the date of the clinical diagnosis [35] The exposure of the study was CPP ... diagnosing cancer for 7725 (79%) of the cases [28, 34] (Fig 1) Subsequently, the study population was restricted to the 79% of patients who had attended gen-eral practice before the cancer diagnosis ... referred patients, it seems feasible that CPP implementation have, at least partially, improved the prognosis Conclusion This study supports the hypothesis that the prognosis of symptomatic cancer patients

Ngày tải lên: 06/08/2020, 03:59

10 8 0
Improving the assessment of quality of life in the clinical care of myeloma patients: The development and validation of the Myeloma Patient Outcome Scale (MyPOS)

Improving the assessment of quality of life in the clinical care of myeloma patients: The development and validation of the Myeloma Patient Outcome Scale (MyPOS)

... A R T I C L E Open AccessImproving the assessment of quality of life in the clinical care of myeloma patients: the development and validation of the Myeloma Patient Outcome Scale (MyPOS) Thomas ... solution These solutions were all tested As the 3-component so-lution supports the factors derived from the theoretical model of QOL in myeloma, this was forced in the SPSS programme Table 2 shows the ... patients The model suggested that the presence or absence of physical symptoms per se was not the most important determinant of QOL, but rather the impact of symptoms on other domains such as activities,

Ngày tải lên: 30/09/2020, 12:45

12 27 0
The cost of lost productivity due to premature cancer-related mortality: An economic measure of the cancer burden

The cost of lost productivity due to premature cancer-related mortality: An economic measure of the cancer burden

... terms of numbers of deaths to 9th in terms of total premature mortality costs These changes are driven by the difference between the distribution of the ages of death for individual cancers and the ... individual cancers, they fail to yield an estimate of the overall burden of cancer-related premature mortality on the economy Also, cancer con-trol initiatives are often site-specific so estimates of ... Ireland), the emergence of cancers of the brain & CNS as the second most expensive in terms of cost per death in males and females is more interesting For can-cers of the brain & CNS, age of

Ngày tải lên: 05/11/2020, 00:56

10 8 0
Design of the remote patient monitoring system (e health) using wireless sensor networks

Design of the remote patient monitoring system (e health) using wireless sensor networks

... được theo chuẩn LED 7 đoạn thì sẽ thu được giá trị đo SPO2 và nhịp tim [34] Các giá trị SPO2 và nhịp tim được đo theo giờ gian thực Hình 5.7 Giao tiếp song song với MSP430F6659, giải mã dữ liệu theo ... 2 phần Firmware và software  Firmware: Phát triển phần mềm nhúng trên MCU.Các lưu đồ trạng thái, xác định và gửi, thời gian lấy frame, thời gian tính toán nhịp tim,…  Software: Sử dụng hệ ... tự động thông minh  Quản lý tiêu thụ điện năng, gas, nước  Theo dõi căn hộ khi không có ai ở nhà và báo về cho chủ  Giúp bác sĩ theo dõi bệnh nhân mà không cần liên tục ở gần bệnh nhân Ngoài

Ngày tải lên: 23/01/2021, 11:05

121 50 0
UNITED STATES’ MEMORANDUM OF LAW IN SUPPORT OF THE CONSTITUTIONALITY OF THE AMERICANS WITH DISABILITIES ACT TABLE OF CONTENTS

UNITED STATES’ MEMORANDUM OF LAW IN SUPPORT OF THE CONSTITUTIONALITY OF THE AMERICANS WITH DISABILITIES ACT TABLE OF CONTENTS

... MEMORANDUM OF LAW IN SUPPORT OF THE CONSTITUTIONALITY OF THE AMERICANS WITH DISABILITIES ACT Trang 2TABLE OF CONTENTS PAGE INTRODUCTION 1SUMMARY OF ARGUMENT 3ARGUMENT: I TITLE II OF THE AMERICANS WITH ... raised for the first time the question of whether Congress has the power, under title II of the ADA, to require theStates to provide health-related services to persons with disabilities in the most ... light of the evil presented.” Ibid Therefore, this Court must examine both the extent and nature of the discrimination faced by individuals with disabilities, and the appropriateness of the relief

Ngày tải lên: 19/10/2022, 23:42

56 3 0
Complex predicate constructions in vietnamese in support of the extended VP shell hypothesis

Complex predicate constructions in vietnamese in support of the extended VP shell hypothesis

... according to their different syntactic behavior with respect to the thematic hierarchy Only the lam causatives show thematic constraints, therefore they are the focal point of the paper Trang ... that telicity of the predicate must be guaranteed the presence of a group of particles that can occur between the main verb and the direct object' For instance, the interpretation of the particle ... the object of the whole complex That is to say, the particle on its own is not predicated of the object” In this seritence, the particle ‘dugc’ (obtain) says nothing about the properties of the

Ngày tải lên: 24/10/2022, 15:00

23 2 0
critical care considerations in the management of the trauma patient following initial resuscitation

critical care considerations in the management of the trauma patient following initial resuscitation

... initialmanagement of the traumatized patient, the transition be-tween early resuscitation of the critically injured patient with hemorrhage and/or polytrauma and the ICU has received less attention These patients ... an issue for these patients The nature and severity of the injuries and the amount of resources already expended should certainly factor into the equation of when to discontinue further resuscitative ... to the ICU the patient’s coagulation status may be in any of these states It is essential therefore to promptly re-assess the patient’s coagulation status in order to initiate ap-propriate therapy

Ngày tải lên: 01/11/2022, 09:49

15 3 0
essential role of the cancer stem progenitor cell marker nucleostemin for indole 3 carbinol anti proliferative responsiveness in human breast cancer cells

essential role of the cancer stem progenitor cell marker nucleostemin for indole 3 carbinol anti proliferative responsiveness in human breast cancer cells

... direct the development of therapy-resistant tumors and relapse of the disease, which significantly influences the effectiveness of a therapeutic strategy [8,9] Therefore, a critical issue in cancer ... similar levels of HER2 protein, the ability of 10AT-Her2 cells to form tumorspheres cannot be attributed only to the high level of exogenous HER2 To compare the expression of cancer stem/progenitor ... MDA-MB-231 breast cancer cells express approximately 30% of the levels of nucleostemin compared to either 10AT-Her2 or SKBR3 cells The production of ALDH-1 was not detected in ei-ther 7 cells or

Ngày tải lên: 02/11/2022, 09:25

22 6 0
natural compounds as regulators of the cancer cell metabolism

natural compounds as regulators of the cancer cell metabolism

... over the years in the development of different classes of therapeutic agents reducing cancer cell proliferation or inducing cancer cell death The main target of these studies was the differential ... susceptibility of cancer versus normal cells to these treatments Over the time, however, we have also learned about the limits of this approach considering the high incidence of therapeutic failure and the ... in cancer The availability of recent sophisti-cated experimental approaches to study the metabolic profile of cancer cells has allowed identification of an impressive number of alterations They

Ngày tải lên: 10/11/2022, 16:34

17 3 0
Catalytic competence, structure and stability of the cancer associated r139w variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1)

Catalytic competence, structure and stability of the cancer associated r139w variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1)

... stability of the protein and to a loss of the FAD cofactor On the other hand, the involvement of NQO1*3 in the development of cancer is currently unclear Initial observations indicated that splicing of ... loss of enzymatic activity is increasing the toxicity of benzene as well as aggravating the cancer treatment of patients [18] The broad substrate specificity of NQO1 allows the activation of chemotherapeutic ... the nqo1 gene (NQO1*3) Initial analysis of the recombinant R139W variant by UV-visible absorption spectroscopy indicated that the affinity of the FAD cofactor as well as the nature of the cofactor

Ngày tải lên: 19/11/2022, 11:48

27 3 0
Ebook Transfusion management of the obstetrical patient: A clinical casebook - Part 1

Ebook Transfusion management of the obstetrical patient: A clinical casebook - Part 1

... accus-tomed to the importance of keeping a patient normothermic in the operating room, but the obstetric provider should be vigilant to prevent hypothermia in the patient bleeding outside of the operating ... 16Risks of the high-risk delivery had been explained to the patient ahead of time. Do You Agree or Disagree with the Management? I agree with the management Given the lack of evidence to support ... As the first round of the MTP (6:6:1—RBC, plasma, apheresis platelet) was being prepared, the blood bank notified the transfusion medicine physician of the Obstetric (OB) MTP (0330 h) The patient

Ngày tải lên: 19/11/2022, 19:56

121 7 0
báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot

báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot

... as a major motivational theme as it demonstrates yet another dimension of the QOL Appraisal Profile and further helps elucidate the nuances of the profile The major theme of reaching an event/ ... of the study, gathering of the data, analysis of data, and drafting of the publication BB and GD helped to develop the study, write the protocol, recruit patients, and write the introduction of ... measures Completeness of Data Due to the complex nature of treating patients with bladder cancer, the difficult course leading up to the surgery, and the method of retrieval of the survey, several...

Ngày tải lên: 20/06/2014, 15:20

18 583 0
Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps

Báo cáo khoa học: "Recent advances in the surgical care of breast cancer patients" pps

... avoid radiation therapy plays a role in the decision process New options are now available for these women and they represent the forefront of the surgical therapy for breast cancer patients Oncologic ... Effect of radiotherapy and surgery in early breast cancer An overview of the randomized trials N Engl J Med 1995, 333:1444-55 64 EBCTCG: Effects of radiotherapy and of differences in the extent of ... standard of care for breast cancer patients around the world, the incidence of local recurrence (LR) has been widely studied It occurs in 5-10% of patients at 10 years, and it is more pronounced in the...

Ngày tải lên: 09/08/2014, 03:21

17 514 0
Tài liệu Nutritional Care of the Housebound Elderly pptx

Tài liệu Nutritional Care of the Housebound Elderly pptx

... factors of undernutrition should use the mini nutritional assessment to determine the nutritional status of the patient before treatment proceeds If the patient is undernourished or at risk of undernutrition ... flats, often alone and widely scattered across the streets and suburbs of Australia and there is no register of who they are We hope the meeting of November 2005 will increase awareness of the community, ... nutrition of disabled and frail old people in their own homes CNOA is part of the Nutrition Research Foundation of the University of Sydney The major funding for the Conference comes from the Australian...

Ngày tải lên: 13/02/2014, 18:20

41 570 1
Tài liệu Assessment of the AHRQ Patient Safety Initiative pptx

Tài liệu Assessment of the AHRQ Patient Safety Initiative pptx

... involved in patient safety We adopted a national perspective, the goal of which was to assess the progress of the AHRQ initiative and the activities of other federal agencies in the context of the larger ... standards of practice Recent Events Two major events during 2003–2004 either have altered the scope of the patient safety initiative or were expected to so One of these was the shift in focus of patient ... and by extending the resources and reach of the agency for translation and diffusion of practices THE PRODUCT EVALUATION AND SELECTION OF MEASURES To assess the effects of the patient safety initiative,...

Ngày tải lên: 18/02/2014, 01:20

101 339 0
Tài liệu Live Red in support of the Heart and Stroke Foundation of Manitoba pdf

Tài liệu Live Red in support of the Heart and Stroke Foundation of Manitoba pdf

... lesser of 10% of the value of the gift and $75, then the value of the advantage is considered to be zero For example, if the price to attend the benefit dinner is $200 and the value of the dinner ... only if the bid amount exceeds the value of the item by 20% The amount of the receipt is equal to the difference between the bid amount and the value of the item Can a charity issue an official ... the value of the dinner is $40 and the value of a gift bag received is $45, then the total advantage is $85 or 85% of the ticket price and therefore cannot be receipted However if the value of...

Ngày tải lên: 19/02/2014, 03:20

57 558 0
HEALTH AND NUTRITIONAL STATUS OF THE ELDERLY IN THE FORMER YUGOSLAV REPUBLIC OF MACEDONIA pot

HEALTH AND NUTRITIONAL STATUS OF THE ELDERLY IN THE FORMER YUGOSLAV REPUBLIC OF MACEDONIA pot

... the distance from the tip of the left middle finger to the sternal notch (in cm, to the nearest 0.1 cm) Total arm-span Measure the distance from the tip of the left middle finger to the tip of ... region (the others are Japan and the United States), with 13.2–17.9% of their population already over 65 years In these countries, the increase in the elderly population will be of the order of 30–140% ... benefit the elderly (http://www.helpage.org/) The nutrition of elderly people: Report of the Working Group on the Nutrition of Elderly People of the Committee on the Medical Aspects of Food Policy...

Ngày tải lên: 05/03/2014, 18:20

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