... evaluation of the long-term safety and efficacy of risperidone in adolescents with schizophrenia Gahan Pandina, Stuart Kushner, Keith Karcher and Magali Haas* Abstract Background: Data on the long-term ... documented the safety and tolerability of risperidone in disruptive behavior disorders over a period of 1 year or longer [15,16], data on the long-term safety and tolerability of risperidone in adolescents ... in one of two short-term, double-blind, controlled clinical stud-ies (NCT00088075 and NCT00034749) assessing the short-term efficacy and safety of risperidone (Figure 1) [8,9] Inclusion and exclusion
Ngày tải lên: 14/01/2020, 20:36
... Trang 1Modeling the Effects of Fire on the Long-Term Dynamics and Restoration of Yellow Pine and Oak Forests in the Southern 3 Knowledge Engineering Laboratory, Department of Entomology, Texas A&M ... species intolerant of fire, and also favored the development of dense stands of stressed trees that are vulnerable to insect infestation and disease (Schowalter et al., 1981; Coulson and Wunneburger, ... Mountains and likely promoted oak and pine (Harmon et al 1983; van Lear and Waldrop 1989; Delcourt and Delcourt 1997; Delcourt and Delcourt 1998) Paleoecological analyses of sediment charcoal and
Ngày tải lên: 18/10/2022, 16:43
juvenile idiopathic arthritis in adulthood fulfilment of classification criteria for adult rheumatic diseases long term outcomes and predictors of inactive disease functional status and damage
... discussion of a new classification capable of better unifying the lan-guage between paediatric and adult care and to contribute to a better understanding of the long-term outcomes and consequences of ... and valid for assessment of validation of a radiographic scoring system for the hip in juvenile validation of a clinical index for assessment of long-term damage in adulthood and predictors of ... disease and functional impairment at long-term follow-up Younger age at disease onset showed to be predictive of higher HAQ, JADI-A and JADI-E and decreased the chance of inactivity of the disease
Ngày tải lên: 04/12/2022, 15:00
long term safety and stability of angiogenesis induced by balanced single vector co expression of pdgf bb and vegf164 in skeletal muscle
... by specific VEGF doses; and 2) the safety of long-term co-expression of VEGF and PDGF-BB in a therapeutically relevant range of doses A major hurdle has been the paucity of tools available to precisely ... effects, and b) the long-term safety and stability of angiogenesis induced by balanced and constitutive co-expression of VEGF and PDGF-BB in the therapeutic target tissue of skeletal muscle Results ... delivery, with the goal of improving safety and efficacy of therapeutic angiogenesis However, long-term expression, which may be nec-essary to ensure stabilization and persistence of induced angiogenesis,
Ngày tải lên: 04/12/2022, 15:15
Long-term outcomes and recurrence pattern of 18F-FDG PET-CT complete metabolic response in the first-line treatment of metastatic colorectal cancer: A lesion-based and patient-based
... gen-erated with long-term follow-up of 47 months was also reflective of real-world clinical practice In summary, our results provided additional information on the long-term outcomes and pattern of recurrence ... PET-CT and complete eradication of disease Normalization of 18 F-FDG uptake in metastases after chemotherapy has been described as CMR but the long term outcomes and recur-rence pattern of these ... response (CMR) • Median number of chemotherapy cycles received after CMR was achieved Trang 6highlighted the long-term outcomes and recurrence pat-terns The PFS and OS of 15.6 and 44.6 months, respect-ively,
Ngày tải lên: 03/07/2020, 01:26
Long-term effects and psychological adjustment: Study protocol of a large register-based study on quality of life among survivors of hematological malignancies
... Götze and Anja Mehnert Abstract Background: Both incidence and survival rates of hematological cancers are increasing, leading to a growing number of survivors with specific late and long-term ... to investigate the different domains of quality of life among long-term survivors of hematological cancers and to identify factors predicting high quality of life Methods/Design: This is a large ... assessment of different domains of quality of life will ensure novel and robust results A limitation of the study is the cross-sectional design Keywords: Hematological malignancies, Long-term effects,
Ngày tải lên: 06/08/2020, 06:13
Long term outcome of anastomotic leakage in patients undergoing low anterior resection for rectal cancer
... [14] Therefore, the objective of our study is to report and analyse long-term oncological and functional outcome in a homogeneous population of patients with AAL and SAL who had undergone curative ... differentiation grade as well as presence of vascular, lymphatic or peri nervous emboli were stated in pathology report Long-term outcomes Long-term functional and oncological outcomes were re-corded in all ... patient and included demographic parameters, primary tumor characteristics, neoadjuvant treatment, intraoperative and pathology vari-ables, as well as short-term and long-term oncological and functional
Ngày tải lên: 20/09/2020, 19:02
Effect of paste content on long-term strength and durability performance of green mortars
... quantities of both fly ash and crushed sand corresponding to the highest density of blended materials are determined, with the maximum weight ratio of blended fly ash and crushed sand (αmax, ... for long-term properties On the other hand, increasing paste content increased porosity and compressive strength, however, it reduced thermal conductivity and UPV of the green mortars All of the ... strength and durability of concrete [13], which may apply for mix design of the green mortars with consideration on both long-term strength and durability performance The main objective of this
Ngày tải lên: 05/07/2022, 11:22
Associations of childhood trauma with long-term diseases and alcohol and nicotine use disorders in Czech and Slovak representative samples
... higher percentage of occurrence of long-term diseases, Trang 6Table 2 Odds ratios of the occurrence of long-term diseases in association with various types of childhood trauma in Czech and Slovak representative ... concurrent occur-rence of emotional abuse and neglect, combined trauma (more than 3 types of trauma) and long-term diseases and alcohol and nicotine use disorder in Czech and Slo-vak national representative ... maltreatment and long-term diseases are stronger overall Emotional abuse predicts the occurrence of all the studied long-term diseases, and the concurrent occurrence of emotional abuse and neglect
Ngày tải lên: 31/10/2022, 03:15
long term changes in numbers of geese stopping over and wintering in south western poland
... flyways which included geese occurring in Poland Trang 4We also compared the long-term and the short-term rates of change in population size between SW Poland and the total flyways, in these three species ... of Silesia for these years The most recent survey was carried out during three periods: the second half of November 2009 and 2010, mid-January 2010 and 2011, and the beginning of March 2010 and ... Academy of Sciences, 60-809 Poznań, Poland Andrzej Wuczyński1,*, Bartosz Smyk1, Paweł Kołodziejczyk1, Wiesław Lenkiewicz1, Grzegorz Orłowski2, Andrzej Pola1 Long-term changes in numbers of geese
Ngày tải lên: 02/11/2022, 14:23
modeling long term uptake and re volatilization of semi volatile organic compounds svocs across the soil atmosphere interface
... Temperature-driven diurnal concentration changes and the height and the stability of the atmo-spheric boundary layer do not affect the long term uptake and release of pollutants from soils A sensitivity ... Long-term soil-atmosphere exchange of SVOCs is controlled by the soil • Reduction of atmospheric pollution leads to short-term re-volatilization of pollutants • On the long term soils generally are sinks ... and transport in soils in the short term is dominated by diffusion, whereas in the long term groundwater recharge and biodegradation become relevant As expected, sorption causes retardation and
Ngày tải lên: 02/11/2022, 14:39
faim l regulation of xiap degradation modulates synaptic long term depression and axon degeneration
... Comella2,3,4 Caspases have recently emerged as key regulators of axonal pruning and degeneration and of long-term depression (LTD), a long-lasting form of synaptic plasticity However, the mechanism underlying ... levels of XIAP and FAIM-L were determined by Western blot 48 h after infection with overexpressing and silencing vectors Data are represented as the mean ± standard error of the mean (SEM) of three ... activation of calpain by caspase-3 degradation of its inhibitor calpastatin Therefore, one of the characteris-tic features of pruning is the appearance of degraded substrates of calpains such as neurofilament
Ngày tải lên: 04/12/2022, 10:34
long term ground deformation patterns of bucharest using multi temporal insar and multivariate dynamic analyses a possible transpressional system
... exponent provides a measure of the long-term memory and the fractality of a time series and, consequently, it can be used as a numerical estimate of the predictability of a time series It is defined ... a geological and geomorphological point of view and the PS InSAR processing of the ERS data returned a density of approximately 1500 PS/km2 between 1992 and 2000 The processing of the ENVISAT ... linearity or nonlinearity, and long memory, may affect the stability and the performance of any classification Each one of these measures and properties was analysed and the main achievements
Ngày tải lên: 04/12/2022, 15:08
long term outcome of hematopoietic stem cell transplantation for il2rg jak3 scid a cohort report
... in techniques and supportive care have led to better survival 4,5 However, most publications described long-term outcome of the entire SCID cohort, irrespective of the genotypic and phenotypic ... questionnaires, and performed the statistical analysis and interpretation of the data and the writing of the manuscript MS, FMK, MP and ARG contributed equally to the conceptualization of the research, ... health-related quality of life (QoL) and presence or absence of on-going medical issues, which may be dependent on Trang 4prior use of a preparative regimen Therefore, we aimed to assess the long-term immune
Ngày tải lên: 04/12/2022, 15:13
preoperative adjuvant transarterial chemoembolization cannot improve the long term outcome of radical therapies for hepatocellular carcinoma
... grasped instead of directly pinching the vessels When necessary, the liver pedicle was intermit-tently clamped in cycles of 10 min of clamping and 5 min of reperfusion In cases of bleeding, the ... the donation was voluntary and altruistic, and we informed the donors and their families of the possible 1-, 3-, and 5-year overall survival rate (%) P value 1-, 3-, and 5-year tumor-free survival ... strictly under the guidelines of the Ethical Committee of our hospital, the regulations of the Organ Transplant Committee of Sichuan Province and the Declaration of Helsinki No prisoners served
Ngày tải lên: 04/12/2022, 15:50
báo cáo hóa học: " Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression" docx
... Levels of components of the TLR-4 signaling pathway, of LPS and of different inflammatory, oxidative/nitrosative and anti-inflammatory mediators were measured by RT-PCR, western blot and/or ELISA ... cortex of rats exposed to an animal model of depression This activa-tion occurs with increased levels of the pro-inflamma-tory cytokine IL-1b and of one of the main enzymatic sources of inflammatory ... production of pro-inflammatory cytokines, expression of COX-2 and, as a co-factor, activity of indoleamine 2,3-dioxygenase (IDO), which reduces levels of 5-HT, a hallmark of depression On the other hand,
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "Long-term outcome and prognosis of dissociative disorder with onset in childhood or adolescence" pot
... characteristics and outcome of children and adolescents with conversion disorder Indian Pediatr 2002, 39:747-752 Ghosh JK, Majumder P, Pant P, Dutta R, Bhatia BD: Clinical profile and outcome of conversion ... the statements of patients and controls with respect to their family of origin, to friendship and social contacts as well as to partnership and sexuality Most of the patients and controls reported ... writing of the paper and are entirely responsible for the scientific content of it: TJ participated in the design and organization of the study, performed parts of the statistical analysis and drafted...
Ngày tải lên: 13/08/2014, 18:21
Tài liệu The long-term reproductive health consequences of female genital cutting in rural Gambia: a community-based survey doc
... pp 643±653 august 2001 L Morison et al Long- term consequences of FGC in The Gambia secondary level education (3% of Mandinkas, 6% of Fulas and 1% of Wollofs) During interviews with a ®eldworker ... or II operations and two women who reported being sealed had no signs of closure Of the three main ethnic groups, 98% of Mandinkas, 4% of Wollofs and 32% of Fulas had signs of genital cutting ... common and how serious the short- and long- term consequences are is lacking (Obermeyer et al 1999) Hospital-based studies have catalogued types of cutting and morbidity, but give no indication of...
Ngày tải lên: 13/02/2014, 16:20
The Long-Term Labor Market Consequences of Graduating doc
... Put." The Review of Economics and Statistics, 84(3) (August): pp 462482 [28] Oreopoulos, Phil, von Wachter, Till and Andrew Heisz (2006) "The Short- and LongTerm Career E¤ects of Graduating in ... Conditions and Long- Term Outcomes for Economists." The Journal of Economic Perspectives, 20(3) (Summer): pp 143-160 [31] Topel, Robert H and Michael P Ward (1992), "Job Mobility and the Careers of Young ... Starting from a sample of 2,236 individuals, I restrict attention to the 631 of these with at least a college degree Of the 596 of these where year of college graduation can be determined, I focus...
Ngày tải lên: 17/03/2014, 03:20
Báo cáo y học: " Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome" potx
... mutations were detected in 12% of perinatally infected infants born in 1998 and 1999 [13] and in 19.1% of such infants born in 2001 and 2002 [14] In France, between 1997 and 2004, the estimated MTCT ... course of infection and persist for years in replication-competent form [24] Moreover, resistance acquisition and long- term persistence have been described after PMTCT with a single dose of nevirapine ... Figure Resistance analysis of HIV-1 RNA and DNA from the mother-child pair #9 Resistance analysis of HIV-1 RNA and DNA from the mother-child pair #9 Time course of HIV-1 RNA and DNA levels in children...
Ngày tải lên: 12/08/2014, 23:22