japanese response to western imperialism in the 19th century

... and these predictors were independent of sepsis, interval until testing, intubation with etomidate, baseline cortisol and albumin levels The results not only help in predicting a diminished response ... participated in the design of the study and helped to draft the manuscript AG helped to draft the manuscript JG partic-ipated in the design and coordination of the study, and helped to draft the manuscript ... responders, thereby arguing against the former The contribution of low platelets to a low response, independent of sepsis or infection, may be caused by circulating factors promoting platelet

Ngày tải lên: 13/08/2014, 03:21

... Associate, McKinsey & Company “As consulting continues to go deeper into the business analytics space, this book provides great insights into both business frameworks and mathematical concepts to help ... consulting in emerging economies is significantly boosting the industry and expected to continue over the next few years The rapidly growing market demand in emerging economies has helped offset the ... particularly relevant to anyone working in the management consulting industry, as it will shape our industry in the years to come.” –Christian Wasmer, Consultant, The Boston Consulting Group (BCG)

Ngày tải lên: 05/11/2019, 14:22

... encroachment of the French in the second half of the 19th century and the concomitant dwindling of the native rulers’ power Henceforth, while from the very beginning to the end of the 19th century, the ... Vinh in the north to Dinh, then Gia Hoi market-streets in the east of the citadel In 1808, the Nguyen Dynasty built three bridges to connect the citadel and the eastern side32) in order to initiate ... 1875〕 becoming feeble.”12) The very beginning of the 19th century, therefore, was the start of Bao Vinh Market.13) The market in the early 19th century was a 9) Quốc sử quán triều Nguyễn (The Association

Ngày tải lên: 18/09/2020, 11:38

... like to introduce the term lifewide learning to emphasize skills such as self-directed learning, independent information mining, collaborative learning and reflective thinking Others have used the ... I wasprivileged to be invited to deliver keynote addresses Interest in using PBL has surged in numerous training institutionsand secondary schools in Singapore and the region The imple-mentation ... significantimprovement in public services in Singapore It was a modest initiative to highlight new mindsets needed to meet the challenges of theknowledge economy One of the first to win the award, in 2000,

Ngày tải lên: 26/07/2023, 07:37

... through G1 into S phase requires cyclin D-CDK4/6 and cyclin E-CDK2, which phosphorylate the retinoblastoma protein [26] CDK inhibitors (CKIs) are the negative regulators and are grouped into two ... TGF1 [29-32] The aim of the present study was therefore to reveal the role of c-Myc in mitogenic response to TGF1 in nucleus pulposus cells The study was designed to (1) analyze the effect of ... inhibi-tors The mitogenic response to TGF 1 suppressed by pathway inhibitors Figure 7a,b indicate that the same levels of endogenous c-Myc protein were detected in nucleus pulposus cells, independent

Ngày tải lên: 09/08/2014, 01:22

... significantly overexpressed at baseline in poor responders are induced by several cytokines in FLSs, thereby suggesting a role for these cytokines in the resistance to TNF blockade in RA ANOVA: analysis of ... of the staining was heterogeneous, the pictures were taken in order to be representative of the globality of the slide The surface staining (S) and the surface of the nuclei (N) were determined ... at baseline depending on response to therapy, we performed immunostaining experiments on the synovial biopsy specimens obtained from the 25 patients included in the study We evaluated the synovial

Ngày tải lên: 09/08/2014, 14:20

... significant Instillation of fluid into the left lung Figure 1 Instillation of fluid into the left lung The instillation of gastrograffin into the distal trachea of sedated rats in the left lateral ... disease In the current study, histology Cytokine response to chronic aspiration of gastric fluid Figure 7 Cytokine response to chronic aspiration of gastric fluid Cytokine levels were evaluated in the ... diseases, the inflammatory response has not been characterized A novel rodent model of chronic aspiration was therefore developed in order to investigate the resulting innate immune response in the

Ngày tải lên: 12/08/2014, 15:21

... arrest indicative of telomere uncapping within a single cell cycle [18] We hypothesized that, while the response to telomere uncapping in cdc13-1 strains was likely to overlap with the response to ... Hypothetical protein YHR087W Protein involved in RNA metabolism AIR1 YIL079C RING finger protein ARX1 YDR101C Protein associated with the ribosomal export complex ASH1 YKL185W Zinc-finger inhibitor ... measured in the array were lower than those quanti-fied by RT-PCR Expression of genes involved in the response to telomerase deletion The transcriptomic response to telomere uncapping in cdc13-1

Ngày tải lên: 14/08/2014, 21:20

... entry into banking through the chartering process The Federalists retained control of the legislature into the mid-1820s, but Federalist elites were willing to share the privilege of creating banks ... legislature and excluding others from the banking sector This winner-take-all game forced both parties to accommodate banks of the other party and moved the banking sector toward de facto free entry ... Democratic-Republicans began to alter the institutions that governed entry into banking through the chartering process The Federalists retained control of the legislature into the mid-1820s, but Federalist

Ngày tải lên: 15/09/2018, 09:40

... were unaware of the explant histopathology findings The largest diameter of the enhancing portion of the lesions on pre-TACE CT scan was measured in the im-aging phase in which the lesion was ... significant in recent studies [8, 15], none of them have been shown to influence the extension of necrosis in ours In order to further determine what factors can impact HCC response to TACE, we ... prior to the liver transplant were subse-quently reviewed in the same session and compared side-by-side with the pre-TACE CT scan, in order to assess the treatment response The responses to TACE

Ngày tải lên: 17/06/2020, 19:01

... Understanding the factors behind patients’ response to neoadjuvant chemotherapy may be beneficial in determining their personal treat-ment regimen and predicting their overall prognosis Though the ... low to high, in-creasing from 6.8% to 17.4% to 38% (Fig 1e) Further-more, patients in the combined intermediate and high groups exhibited significantly higher rates of pCR com-pared to the low ... determined their accuracy by calculating the AUC, as we did previ-ously (Fig 3) Overall, the accuracy of the E2F4 signature was comparable to the other clinically-available assays in both the discovery

Ngày tải lên: 06/08/2020, 07:53

... similar to the Cdk-binding motif of cyclins [3, 4] and are highly selective in their binding of CDK5 [5] The levels of p35 and p39 are not regulated through the cell cycle suggesting the function ... obtained by excising the stained protein band from the gel and counting in scintillation fluid Western blotting SDS loading buffer was added to cell lysates and samples subjected to electrophoresis ... accurately mimic the fixation and processing of human clinical tissues used in diagnostic histopathology (Fig 3b) The intensity of staining and the number of cells stained with the anti-body to phospho-Ser522

Ngày tải lên: 22/09/2020, 23:40

... confirm these observations for the allosteric mTOR in-hibitor everolimus, providing further evidence that ΔT1 reflects the number of remaining proliferating tumour cells following successful chemotherapy ... histology Since everolimus inhibited tumour growth, there was of course a reduction in the total and viable area and consequently a reduction in the total cell num-ber examined by IHC comparing ... sensitive to a) the amount of water in the extracellular space (but not intracellular) and b) the amount of protein in the water [21-25] It is well recognised that inhibition of mTOR (the molecular

Ngày tải lên: 05/11/2020, 01:11

... to middle intertidal zones 6 A marina 1.9 In the lower intertidal zones along the rivers 1.8 Along the dike into the island, in scattered lower intertidal zones along the rivers 1.4 In high intertidal, ... surveying 113 families During the interviews, the questions and scale were clearly explained to the respondents, facilitating their understanding and engagement with the topic.Data processing was ... mitigating the impact of these storms Additionally, the lack of designated boat shelters forces residents to move their boats deep into the mangrove forest during storms to safeguard their property

Ngày tải lên: 12/12/2021, 21:03

... (2005) The Spanish Royal Philanthropic Expedition to Bring Smallpox Vaccination to the New World and Asia in the 19th Century Clinical Infectious Diseases, 41 (9), pp 1285-1289 Mark, Catherine ... research works, this article examines the situation of smallpox in Vietnam during the Nguyen Dynasty and their effort to access the smallpox vaccine in the early nineteenth century Keywords: smallpox, ... one of the deadliest diseases known to humans In Vietnam, during the Nguyen Dynasty, smallpox was an endemic disease not only causing epidemics in some localities but also influencing the political

Ngày tải lên: 15/10/2022, 16:19

... summarizes some initial results from each data source Next steps to the analysis will be combining all the data into a COVID dashboard to understand the “system” response to COVID-19 within Colombia ... in PEP was either included in the EPS-S scheme or the EPC-C when formally employed Those who remain without PEP, remain in the “non-affiliated” sub-scheme- granting them access to emergent care ... others, staying home without receiving any visitors, avoiding social gatherings of more than 10 people, and using masks in public However, when asked about their perception of the adherence to Social

Ngày tải lên: 22/10/2022, 22:16

... addition, intense storms tend to increase, heavy rain due to storms increases Vietnam's climate at the end of the 21st century has changes similar to the general changing trend of the region and the ... According to the RCP8.5 scenario, the maximum increase could be over 20% in most North In the whole of Vietnam, the maximum daily rainfall tends to increase compared to the baseline period Besides, the ... annual rainfall tends to decrease at most of the northern weather stations In addition, extreme rainfall is significantly reduced in the Northern Delta, and the number of strong storms tends to increase

Ngày tải lên: 23/10/2023, 06:30

... Inaddition, intense storms tend to increase, heavy rain due to storms increases.Vietnam's climate at the end of the 21st century has changes similar to the generalchanging trend of the region and the ... According to the RCP8.5scenario, the maximum increase could be over 20% in most North In the whole ofVietnam, the maximum daily rainfall tends to increase compared to the baselineperiod Besides, the ... (3) carbon storage On the otherhand, I also divided the social role of mangroves into two specific parts, including (1)maintaining people's livelihood and (2) reducing the impact of CC To research

Ngày tải lên: 23/10/2023, 14:38

... existed intermittently. During times of open entrances the bones accumulated. Then all entrances to the cave were apparently sealed between some- time in the Irvingtonian (based on the age of the ... conditions defined variable patterns of filling, resulting in the establishment of bedding patterns. Overall the package of strata becomes finer upward, suggesting [that] the orifice supplying sediments gradually ... the indicator species used in the quantitative climate analysis 308 22.7. Highest temperature (summer) minima and lowest temperature (winter) maxima on the climate space shared by the indicator...

Ngày tải lên: 17/02/2014, 20:20

... from, apoptosis [9,10]. Beclin 1, a class III phosphatidylinositol 3-kinase- interacting protein [11], plays a role in promoting autophagy [12]. Beclin 1 contains a Bcl-2-binding domain which ... MagicRed-Cathepsin B substrate was added to the cells during the last 30 min of an experiment according to the manufacturer’s instructions. Calcium imaging For dye loading, Fluo-4 was dissolved in in ... serve as a point of cross-talk between the autophagic and apoptotic pathways. Recently, a BH3 domain in the Bcl-2-binding domain of Beclin 1 was shown to bind to Bcl-X L [13]. Anti-apoptotic Bcl-2 and...

Ngày tải lên: 07/03/2014, 09:20