ischemia reperfusion injury with long term survival

... study: To evaluate long-term survival outcome of LAG with D2 lymph node dissection for gastric cancer SUBJECTS AND METHODS 1 Research subjects 165 patients were diagnosed with gastric adenocarcinoma, ... Results of follow-up survival Figure 1: Follow-up overall survival Overall 5-year survival rate was 50.3% Figure 2: Follow-up overall survival of sex Overall 5-year survival rates of male ... study on 165 patients with gastric cancer were LAG with D2 lymph nodes dissection, we found that it was technically feasible, safe and a good long-term outcome The median survival was 53.9 ± 31.3

Ngày tải lên: 15/01/2020, 11:56

... T I C L E Open AccessBrain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury Amy A Wilkinson1,2*, Maureen Dennis1,2,3ˆ, ... principle study to determine which combination of injury (Glasgow Coma Scale; GCS) and child (age at injury, sex, SES, and pre-injury functioning) variables and six brain-injury and inflammatory ... microvascular injury and inflammation that may be associated with outcome following TBI This study identifies the characteristics that may be most closely associ-ated with long-term cognitive

Ngày tải lên: 20/02/2020, 22:22

... 1R E S E A R C H A R T I C L E Open AccessThe long-term survival of patients with III-IVb stage nasopharyngeal carcinoma treated with IMRT with or without Nimotuzumab: a propensity score-matched ... of distant metastasis-free survival, locoregional relapse –free survival, progression-free survival, and overall survival of NPC patients treated with (green lines) or without Nimotuzumab (blue ... A total of 6908 consecutive NPC patients who were treated with Table 1 Baseline characteristics of patients with NPC treated with or without Nimotuzumab N = 184(%) No Nimotuzumab Arm Trang 5IMRT

Ngày tải lên: 17/06/2020, 18:19

... clinicopathologic factors affect short-term survival while others are related to long-term survival Controversy regarding the prognostic impact of tumor thrombus in patients with RCC may be at least partly ... also likelihood of aggressive cytoreductive operation in patients with RCC with venous thrombus on short-term and long-term overall survival, the present comprehensive univariate and following multivariate ... Alternatively, patients with a tumor thrombus within the RV had a lower ESR compared with those with a tumor thrombus extending to the suprahepatic IVC Patients with a tumor thrombus within the RV or

Ngày tải lên: 05/11/2020, 05:09

... non-claimants of injury compensation Trang 9working with modified duties with early and appropri-ate intervention may reduce long term individual and societal burden Claiming compensation While injury ... following injury when compared with injury compensation records [44] In our study, post-injury paid work status was classified as ‘full work duties’, ‘modified work duties’, or ‘not in paid work’, with ... derived from the longi-tudinal modelling and presented in terms of relative risk (RR) estimates with 95% confidence intervals (CI) Multi-variable adjustments for preinjury factors, injury factors,

Ngày tải lên: 29/11/2022, 14:22

... associated with high rates of morbidity and mortality Hepatic I/R injury occurs in a biphasic pattern: The acute injury phase is characterized by hepatic injury occurring within 1–6 h after reperfusion, ... Results: Reperfusion caused significant hepatocellular injury in both wild-type and P/I null mice as was determined by plasma ALT levels and liver histopathology The injury was associated with a ... not hepatic I/ R injury would be attenuated in P/I null mice after longer periods of reperfusion, at time points most consistent with the neutrophil-mediated phase of liver injury Methods All

Ngày tải lên: 11/08/2014, 08:21

... variable with survival time was found, in which a lower number of surgical revisions was asso-ciated with a shorter survival time (Figure 5) Discussion Magnitude of short-term and long-term survival ... defined as P < 0.05. Analysis of long term survival beyond the second year after inclusion Kaplan-Meier survival analysis was used to describe long-term survival after the second year after ... prognosis Advanced age was an independent prognostic determinant of poor short-term and long-short-term survival Conclusion Acute and long-term prognosis in chronically critically ill surgical

Ngày tải lên: 13/08/2014, 03:21

... Heart Protection Against Ischemia - Reperfusion Injury Dr Igor Khaliulin Trang 2Coronary Artery Occlusion and Heart Attack Heart Attack Risk Zone Reperfusion Reperfusion INJURY Ischaemia-Myocardium ... Consecutive perfusion with isoproterenol and adenosine Trang 8Consecutive Isoproterenol/Adenosine Treatment Drammatically Improves Haemodynamic Function Recovery During Reperfusion 0 20 40 60 ... treatment of hearts with a PKA activator ( isoproterenol ) and a PKC activator ( adenosine ) results in an extraordinary cardioprotective effect during normothermic (37°C) ischaemia and reperfusion

Ngày tải lên: 30/08/2015, 13:58

... perfused with NaHS-containing HEPES-buffered solution 2.5 Ischemia/reperfusion in isolated rat ventricular myocytes For the cardiac myocytes ischemia/reperfusion experiments, simulated ischemia ... ischemia/reperfusion injury The further functional study showed that perfusion with NaHS significantly improved pos-tischemic contractile function in isolated rat hearts Trang 7subjected to ischemia/reperfusion ... treatment groups: vehicle + ischemia group (myocytes treated with vehicle and subjected to simulated ischemia solution for 30 min), NaHS + ischemia group (myocytes were pretreated with NaHS at 0.1 mM

Ngày tải lên: 02/10/2015, 17:13

... In Prepper’s Long-Term Survival Guide, Jim shares his best advice and strategies for planning for basic needs, including food, hygiene, shelter, warmth, and security Long-term survival requires ... of the world. When we talk about long-term events, we are referring to catastrophes that effectively bring society to a screeching halt, along with all the long-Term evenTs: learning from hisTory ... on the Internet for a long time, and I think with this volume, he’s collected a canon of survival knowledge and training The chapters on survivalism in fiction and the survival library section

Ngày tải lên: 12/03/2018, 09:28

... February 2016 to directly target and assess people with long-term conditions in order to improve quality of life were included Interventions without long-term condition populations, psychological intervention ... interventions to improve quality of life in people with long-term conditions: rapid systematic review of randomised controlled trials Abstract Background: Long-term conditions may negatively impact multiple ... healthcare provision and practice Keywords: Long-term, Physical, Conditions, Psychological, Intervention, Health, Quality, Life, Mental, Wellbeing Background Long-term conditions (LTC) are complex physical

Ngày tải lên: 10/01/2020, 14:45

... modulate ischemia-reperfusion injury There are some researches that platelets play a role to damage an endothelium during I/R injury with thrombosis [19], [20] Therefore, the role of platelet in ischemia-reperfusion ... the ischemia group (Group C) and the ischemia-PRP group (Group D) were cyanotic with adequate ischemia After the removal of microclamp, the flaps showed hyperemic immediately, with apparent reperfusion ... sutured without ischemia In the ischemia group (Group C), the flap was elevated, 120 μl of PBS was injected, and the pedicle was ligated with microclamp (Synovis, AL, USA) for 4 h After ischemia,

Ngày tải lên: 14/01/2020, 22:54

... experimental research Key words: hepatic ischemia-reperfusion injury, ischemic postconditioning, next-generation RNA-Seq, DEGs, MAPK pathway Introduction Hepatic ischemia/reperfusion (I/R), or the interruption ... repetitive cycles of brief reperfusion and re-occlusion applied at the onset of reperfusion after a prolonged ischemic insult, has been used to attenuate organ I/R injury in the heart [12, 13], ... had liver ischemia induced for 1 h and then reperfusion for 4 h The IPO group received occlusion of the porta hepatis for 1 h and was then treated with three consecutive 5-sec cycles of reperfusion

Ngày tải lên: 15/01/2020, 05:49

... LPS on the heart ischemic/reperfusion injury As shown in figure 6, global ischemia/reperfusion (I/R) caused LV myocardial damage and increased the LDH (a myocardial injury biomarker in the perfused ... ischemic injury and dysfunction after the ischemia stimulation in adult offspring [27-29] Our current findings that neonatal LPS treatment caused an increased heart ischemia/reperfusion injury ... functions and the development of a heart ischemia-sensitive phenotype later in life Key words: lipopolysaccharide, neonatal exposure, ischemia/reperfusion injury Introduction Cardiovascular diseases

Ngày tải lên: 15/01/2020, 23:29

... series, the estimated long-term survival was about 90 % at 5 years, 80 % at 10 years and 70 % at 18–20 Fig 4 Survival in patients with known BRCA mutation status Kaplan-Meier survival estimates ... BRCA (p = 0.04) Conclusions: Long-term survival was high in MBC patients referred to our clinical unit Survival was poorer in BRCA-mutated patients than in patients with wild-type BRCA Keywords: ... overall estimated long-term survival was about 90 % at 5 years, 80 % at 10 years and 70 % at 20 years Patients carrying a BRCA mutation had a significantly lower survival than patients with wild-type

Ngày tải lên: 21/09/2020, 01:38

... association of the surrogate marker with long-term survival Sensitivity of pCR as a predictor of survival was low (0.38), indicating that the majority of long-term survivors not achieving pCR following ... to predict long-term survival Sensitivity and specificity as well as the likelihood ratio were analyzed for the different histopathologic regression parameters to predict long-term survival For ... observed survival time according to a back-ward selection proportional hazard model These pa-tients were included in the analysis with weight p as long-term survivors and with weight 1-p as short-term

Ngày tải lên: 30/09/2020, 10:52

... significantly prolonged animal survival (median survival 35 days vs 28 days in vehicle controls) Remarkably, increasing CNF1 concentration to 80 nM resulted in a dramatic enhancement of survival with no ... incubated with CNF1 for 24 hours before Trang 3making the scratch, and wound healing was assessed 8,24 and 48 hours after the injury The cells were then fixed with methanol and stained with crystal ... Fate of GL261 cells after prolonged CNF1 exposure To determine the fate of polynucleated GL261, cells were treated with CNF1 (18 nM) at day one and then cultured without removal of the toxin

Ngày tải lên: 14/10/2020, 17:21

... dexmedetomidine on cerebral ischemia/reperfusion injury via the Wenyi Liu1, Cuihua Shao2, Chuanshan Zang3, Jian Sun1, Min Xu4and Yuna Wang1* Abstract Background: Cerebral ischemia/reperfusion injury (CIRI) ... impairing ROCK1 rats with CIRI Background Cerebral ischemia/reperfusion injury (CIRI) is often in-duced by ischemic stroke which is caused by arterial oc-clusion, leading to long-term disability and ... 0.05 compared with rats injected with NC inhibitor For panel B and E, comparisons were made using one-way or two-way ANOVA, respectively * p < 0.05 compared with rats injected with NC inhibitor;

Ngày tải lên: 12/01/2022, 22:17

... Trang 4Survival rates of each cancerSurvival was highest in patients with breast cancer, followed by patients with colon and stomach cancers; similar mortalities were observed in patients with ... propofol was associated with better survival after surgery in 670 patients with hepatocellular carcinoma [25] For patients with breast cancer, propofol may reduce the relapse rate within 5 years, but ... patients had a long-term survival of 80–90 months Another study of 1538 patients with gastric cancer found that propofol-based TIVA had no significant effect on 1-year overall survival or cancer-related

Ngày tải lên: 13/01/2022, 01:18

... reportreport-ing the occurrence of three or more long-term diseases Conclusion: The extent of reporting childhood trauma and associations with long-term diseases in the Czech and Slovak population ... predict the selected long-term diseases We also hypothesized that the number of child-hood trauma types will be positively associated with the Trang 3occurrence of three or more long-term diseases Another ... operative, high school graduate and college) Long‑term health complaints Long-term health difficulties were detected by the item “Do you have any long-lasting disability or disorder? Please,

Ngày tải lên: 31/10/2022, 03:15