introduction to stem cell biology ppt

... Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine Edited by Sheng Ding Copyright
2008 John Wiley & Sons, Inc. 145 Trang 2biological systems Since a comprehensive ... incorporating stable isotopes involves growing cells in isotopically enriched media For example, one group of cells would be cultured in media that contained14N as the only source of nitrogen atoms, while ... was used to compare the mechanism of divergent growth factor effects on mesenchymal stem cell differentiation [49] Although extremely powerful for the study of biological phenomena in cell culture,

Ngày tải lên: 01/03/2023, 11:31

... 2CHEMICAL ANDFUNCTIONAL GENOMIC APPROACHES TO STEM CELL BIOLOGY AND REGENERATIVE MEDICINE Trang 3CHEMICAL ANDFUNCTIONAL GENOMIC APPROACHES TO STEM CELL BIOLOGY AND REGENERATIVE MEDICINE Edited ... ES cells ES cells can be induced to differentiate into all somatic cell lineages via the formation of three-dimensional EBs or monolayer culture Trang 11FIGURE 2.2 Adult stem cell niche Adult stem ... 12FIGURE 2.3 Discovery of the hematopoietic stem cell (See text for full caption.)Trang 13FIGURE 2.4 Cancer stem cell Two major theories of the cancer stem cell arise from the common theme of

Ngày tải lên: 01/03/2023, 11:33

... should also be directed to children Unlikeadults, children are more likely to indirectly express their fears of dying Anopenness to discuss the topic is often helpful.10 Transfer to the intensive care ... area, 393 Trang 23risk factors for, 210Cardiac physiology, normal, 206-7f Cellular defects, infection due to, 52 Cellular typing, HLA, 33-34 Trang 24Central nervous system (CNS) infection, 234-36, ... behavioral plans to be effective, all team members must agree to follow them to avoidplacing inconsistent expectations on the patient 4 Communication across shifts should be systematically conducted

Ngày tải lên: 10/08/2014, 08:20

... Laboratory, with kind permission Trang 3I Introduction: History 3Archeologists have found hearths and fire-hardened wood spears that date to about 750,000 to 500,000 years BC It is reasonable to ... Discussion Topics References and Recommended Reading Trang 2I IntrODUCtIOn: hIStOrYAir pollution has two histories, an early unrecorded one and a more recent recorded one By examining these histories, ... explain how epidemiology, toxicology, and basic laboratory research are all needed to understand the health effects of air pollution ChAPter OUtLIne I Introduction: History II The Great Air Pollution

Ngày tải lên: 15/03/2014, 20:20

... Trang 1AN INTRODUCTION TO ANDROID FOR DEVELOPERS Trang 3Introduction Goals @ Get you Started with Android Development @ Get the Environment Set Up and Working @ Create Some Demo Apps (Tutorials) ... started and stopped as needed to run an applications components ® Processes killed to reclaim resources Coovgle Trang 26Life Cycle of an Application Trang 27Activities @ Designed to be reused ... Bundles used to pass messages/store state ® onFreeze() has outState bundle passed in Data stored in outstate handed back to onCreate as the icicle bundle Google Trang 30Storage / Persistence ® Normally

Ngày tải lên: 01/04/2014, 10:20

... was to produce a document showing our work for thesemester and also to make available to other students interested in fuel cells or taking an introductory fuel cell course We would like to thank ... the power companiesthemselves move toward a more hydrogen based from of electric power generation.Thus as an introduction to fuel cells we need to study cell cells for two importantreasons First ... infrastructurefor fuel cells first a specific type of fuel cell needs to be chosen so the infrastructurecan correctly be developed to support the specific needs of the cell Also there needsto be several

Ngày tải lên: 23/04/2014, 22:24

... filled TiILEMODE – Set to 0 Paperspace enabled; set to 1 tiled viewports in Modelspace TOOLTIPS – Set to 0 no tool tips; set to 1 tool tips enabled TPSTATE – Set to 0 and the Tool Palettes window ... coordinate system, 15 AutoCAD Help web page, 411 AutoCAD Message window, 149 AutoCAD shortcut, 4 AutoCAD SHX fonts, 146 AutoCAD Text Window, 144 AutoCAD window Close button, 30 Autodesk Design ... 386 Auto-hide icon, 9 AutoCAD-reasons for using, 414 AutoCAD-system requirements, 417 AutoCAD 2011 enhancements, 416 AutoCAD 2011 in designing, 414 AutoCAD Classic workspace, 21, 50 AutoCAD coordinate

Ngày tải lên: 01/07/2014, 19:20

... the indicating thata1 went toa2,a2 toa1,a3 toa4, and a4toa3 If we always choose the top row to be 1 2 3 4 then, to prescribe the permutation, we need only give the bottom row, with the understanding ... isasymptotically equal to b n, and writea n ∼ b n, if ratio tends to 1 asn tends to infinity, we have a n ∼ b n 2 Theorem 3.3 (Stirling’s Formula) The sequencen! is asymptotically equal to n n ... The total number ofk-permutations of a set A of n elements is given Factorials The number given in Theorem 3.1 is called n factorial, and is denoted by n! The expression 0! is defined to be 1 to

Ngày tải lên: 04/07/2014, 10:20

... variance does not seem to increase or decrease from onegeneration to the next This was known at the time of Galton, and his attempts to explain this led him to the idea of regression to the mean This ... themselves in some sense conformable to it Galton invented a device known as a quincunx (now commonly called a Galtonboard), which we used in Example 3.10 to show how to physically obtain a binomialdistribution ... Theparent population is shown at the top of the figure, and the slanted lines are meant to correspond to the reversion effect The offspring population is shown at thebottom of the figure 11 ibid., p

Ngày tải lên: 09/08/2014, 23:20

... co-cultured CD34+ hematopoietic stem cells with 3A6 cells, we noted the formation of cobblestone areas from hematopoietic cells that transmigrated beneath the layer of 3A6 cells (Figure 3C) Previously, ... out the expression profile of the cells converged toward embryonic stem cells These data demonstrate these cells not only are a useful tool for the studies of cell differentiation both for the ... Downregulation of the embryonic transcription factors such as Oct4 and Nanog is associated with differentia-tion of neural stem cells, hematopoietic stem cells and MSCs However, an increase in Oct4

Ngày tải lên: 10/08/2014, 05:21

... Guide to Stem Cell and Bone Marrow Transplantation Trang 18Page 1Introduction to Stem Cell and Bone Marrow Transplantation The pluripotent stem cells from which all committed blood cells arise ... blood stem cells 118 Chapter 5 Management of Stem Cell/Bone Marrow Transplantation Complications Terry Wikle Shapiro, Deborah M Rust, Deborah Branney Davison Trang 17Page iA Clinical Guide to Stem ... viiContents Introduction to Stem Cell and Bone Marrow Transplantation Terry Wikle Shapiro Trang 12Antimicrobial prophylaxis 85Trang 13Page viiiChapter 4 Bone Marrow, Peripheral Blood Stem Cell, and

Ngày tải lên: 10/08/2014, 08:20

... a cell cycle specific antitumor therapy 4 Cyclophosphamide was added to radiation therapy because it was found to be an effectivecytotoxic approach and appeared to have few nonhematopoietic toxicities ... factors) C Medical evaluation 1 Complete medical history 2 Attention to chronic medical problems 3 Medications 4 Pregnancy history (female) 5 Anesthesia history 6 Transfusion history 7 History ... found to be the dose-limiting toxicity Indose escalation studies of etoposide combined with 12- or 13.2-Gy fractionated TBI, 60mg/kg of etoposide was found to be the maximum tolerated dose; stomatitis

Ngày tải lên: 10/08/2014, 08:20

... started around day +7 to +8 post-transplant c) Interleukin-3 (IL-3) is used to stimulate the earliest progenitor cells of all celllineages (red cell, platelets, and white cells) May decrease the ... Colony-stimulating factors6, 7, a) Granulocyte-macrophage colony-stimulating factor (GM-CSF); Leukine (Prokine) is a multilineage colony-stimulating factor glycoprotein used to stimulate earlyprogenitor cells ... is 2 to 3 mg/kg/d IV divided q12h or by 24-hour continuous, infusionstarting 1 to 3 days prior to marrow infusion; q12h infusion may be infused over 1 to 6 hours When patients are able to tolerate

Ngày tải lên: 10/08/2014, 08:20

... thought toresult from marrow rejection by host T cells not eliminated during conditioning 9d) T-cell depletion of donor marrow to prevent GVHD also contributes to graftrejection e) In the autologous ... setting, graft failure is thought to be due to infusion ofinadequate numbers of stem cells, ex vivo manipulation of marrow (purging), andcryopreservation.3 3 Risk factors a) Recipient of HLA-incompatible ... Presence of white cells suggests bacterial infection, althoughneutropenic BMT patients are unable to mount white cell response c) Stool from viral culture and electron microscopy to rule out viral

Ngày tải lên: 10/08/2014, 08:20

... Development of counterbalancing regulatory cells e) Development of circulating autoantibodies 3 Risk factors a) History of acute GVHD b) Increased age (> 20 years) c) T cell—depleted marrow recipient ... Urologic system: renal involvement (nephrotic syndrome) and bladderinvolvement (severe cystitis) r) Hematopoietic system: Eosinophilia and thrombocytopenia, platelet-boundautoantibodies, autoimmune ... described that contribute to the pathogenesis ofchronic GVHD.a) Initiation by donor T cells b) Persistence of circulating alloreactive T cells c) Development of autoreactive T cells d) Development

Ngày tải lên: 10/08/2014, 08:20

... malabsorption.d) Stool electrolytes: Secretory diarrhea tends to have an elevated stool sodium and alower osmotic gap (< 100 mOsm/L) In malabsorption or viral illness, the stool tends to have a decreased ... Guide to Laboratory Medicine Philadelphia: WB Saunders Co; 1993:73–77 Witherspoon RP Immunological reconstruction after allogeneic marrow, autologous marrow or autologous peripheral blood stem cell ... ventricular function) 2 Application: to determine cardiac function prior to conditioning regimen therapy or toassess toxicity of therapy 3 Advantage: sensitive test to determine cardiac function 4

Ngày tải lên: 10/08/2014, 08:20

... anemia, thrombocytopenia(Monistat) Topical: 2% (30 g) Topical: Apply 1–2 times per dVaginal supp: 100, 200 mg Vaginal: 1 applicator of cream (100 mg) qhs for 7 d OR 200-mg suppositoryqhs for 3 d ... perdose q8 h for 10 dTopical HSV treatment: 1/2 inch ribbon toaffected area 6 times perd Treatment of varicellazoster virus (VZV)infection: Children: 10–20 mg/kgper dose up to 800 mg 4times per ... mg IV q10–20 min; up to 30 mg/8h; may repeat in2–4 h Transdermal: Initial: 25 mg/24 h patch If patient is takingopiates; convert tofentanyl equivalent Toconvert from oral to IV,the previous 24

Ngày tải lên: 10/08/2014, 08:20

... anyfaith-based dietary practices 4 Lactose intolerance: Identify any preexisting symptoms with ingestion of lactose-containing foods and beverages and whether lactose therapy has been beneficial in ... depleted (filtered) and irradiated 5 Irradiation, gamma type (15 to 25 Gy), is used to inactivate viable T cells in the bloodproduct to prevent transfusion-induced graft-versus-host disease (GVHD) ... plateletrefractoriness b) Reduce the transmission of cytomegalovirus (CMV) and nonhemolytic febrilereactions II Blood and Blood Products A Red blood cell transfusions 1 Indications a) Cytomegalovirus

Ngày tải lên: 10/08/2014, 08:20

... was effectively added to the crack length, leading to disaster. Modern aircraft are built with this failure mode in mind, and have “tear strips” that are supposedly able to stop any rapidly growing ... 3multiple small cracks to link up to form a large crack A great deal of attention is currently being directedto protection against this sort of “multi-site damage.” It is important to realize that the ... apply in modes IIand III The equations show three factors that taken together depict the stress state near thecrack tip: the denominator factor (2πr)−1/2shows the singular nature of the stress

Ngày tải lên: 11/08/2014, 09:21

... is 10 (略) Router#terminal history size ? <0-256> Size of history buffer Router#terminal history size 25 Router#sh terminal (略) History is enabled,history size is 25 (略) Gather ... 1.show history:显示最后输入的 10 条命令,默认是 10 条,可以修改该值 2.terminal history size:修改显示最后输入过的的命令的数量,默认是 10 条,最大是 256 条 3.show terminal:显示命令历史缓存大小,如下: Router#sh terminal (略) History is enabled,history size ... 2.Ctrl+E:把光标快速移动到整行的最末尾 3.Esc+B:后退 1 个单词 Chapter4 Introduction to the Cisco IOS The Cisco Router User Interface Cisco Internetwork Operation System(IOS)是 Cisco 的 routers 和 switches 的内核 Cisco...

Ngày tải lên: 10/12/2013, 16:15