... “be Undone, / By the departure of a star, / while they enjoy the Sun” (Meserole ) The living God who had authored the sanctity of the dead was poised to fill the space created by their leaving ... reaction to the vision of the valley of dry bones, the divine question and the human answer describe the Puritan response to the challenge of writing resurrections for the dry bones of the holy ... these poems indeed prepared readers to take the place of the deceased, this would occur only if the spirit of the dead infused the living Only through the survivor’s genuine assimilation of the...
Ngày tải lên: 01/11/2013, 10:20
Tài liệu The Beginnings of New England docx
... dates, by the way, we realize the import of the saying that in the sight of the Lord a thousand years are but as a day, and we feel that the work of the Lord cannot be done by the listless or the ... remarkable The grandchildren of the men who had witnessed the spectacle of a king of France and a king of England humbled at the feet of Innocent III., the children of the men who had found the gigantic ... of the feudal nobility, whether on the field or under the headsman's axe This was a conspicuous feature of the feuds of the Trastamare in Spain, of the English invasions of France, followed by...
Ngày tải lên: 21/02/2014, 08:20
Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... Mutation of the octamer in the iNOS and G-CSF promoters results in a reduction of more than 90% in the LPS-induced promoter activities of these genes [13,30], suggesting the essential role of the ... attributed to the decrease in Oct-2 expression caused by these reagents The involvement of Oct-2 in iNOS and G-CSF expression was further supported by the finding that knockdown of Oct-2 expression ... concentration of G-CSF protein in the medium was measured by ELISA (B) The values for the LPS-treated cells were divided by those for the non-LPS-treated cells and are shown as a percentage of the values...
Ngày tải lên: 22/03/2014, 17:20
The Beginnings of Cheap Steel pot
... regardless of the strength of the vested interests involved The provocation came from his claims that the product of the first stage of the conversion was the equivalent of charcoal iron, the processes ... interest the British War Office in the idea led him to submit his design to the Emperor Napoleon III Trials made with the encouragement of the Emperor showed the inadequacy of the cast-iron guns of the ... Steel, by Philip W Bishop 16 One of Mushet's replies to the paper itself took the form of the announcement of his provisional patent for the use of his triple compound which, in the opinion of The...
Ngày tải lên: 23/03/2014, 17:20
Báo cáo khoa học: Structural determinants of protein stabilization by solutes The importance of the hairpin loop in rubredoxins pdf
... (n) The lower plots show the difference of the coefficients in the presence of (B) DGP or (C) MG relative to water The points on the horizontal axis cover the entire sequence of residues of the ... for some of these residues (Fig 3) In particular, the exposure of the residues that comprise the lower part (relative to the orientation depicted in Fig 2) of the hydrophobic core of the native ... series of mutants of RdDg was constructed to investigate the importance of these mutations on the degree of stabilization rendered by solutes It is well-documented that the thermal denaturation of...
Ngày tải lên: 30/03/2014, 15:20
SHOPPER MARKETING: How to increase purchase decisions at the point of sale
... contents of the book are compiled from 37 global practitioners and professionals of shopper marketing The extensive list of authors covers nearly all of the worldrenowned experts of the area The best ... what is the business situation of the manufacturer at the retailer, and what is the performance of the retailer within the category? For both questions the key challenge is then to find the ‘why’ ... the marketplace Shopper Marketing is the first book providing an extensive outlook into the various aspects of this new area of marketing Because of the emerging nature of the new practice, the...
Ngày tải lên: 07/04/2014, 12:41
Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf
... to the standards of animal care as outlined in the Guide for the Care and Use of Experimental Animals of the Medical College of Shanghai Jiaotong University The study protocol was approved by the ... counting the cells that migrated to the lower side of the filter with optical microscopy at 400× A total of five visual fields at the center and in the surrounding areas were counted, and the average ... efficiency of the target gene after RNAi The cell line with stable transfection and effective inhibition of the ADAM 10 gene was named SACC-ADAM 10-RNAi, and the cell line with stable transfection of the...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines" pdf
... experiments, analyzed the data, generated the figures, and wrote the manuscript JW did parts of the animal surgery JW, YS, LW, EB performed the experiments PEK provided advice in the design of the study ... (MCAO) was produced by filament occlusion of the right MCA following a modification of the method reported by Clark and colleagues [21] In brief, mice were anesthetized with isoflurane (induction ... regulator of macrophage activation [15] Further investigations by our group and others indicated that MCPIP1 can play a significant antiinflammatory role by inhibiting the generation of a set of major...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB" doc
... inactivation of NF-κB signaling, resulting in the inhibition of cell proliferation and induction of apoptosis (Figure 5) Our hypothesis is also supported by the evidence of down-regulation of the important ... [27,29], and melanoma cells [30], associated with the inhibition in the translocation of p65 subunit of NFκB in the nucleus, which is otherwise increased by the cisplatin treatment http://www.ovarianresearch.com/content/1/1/9 ... sensitize even the drug-resistant cell line and cause inhibition of cell viability Further, to assess whether the loss of overall cell viability could also be due to the induction of apoptotic...
Ngày tải lên: 20/06/2014, 07:20
The Story of Alchemy and the Beginnings of Chemistry ppt
... ART THE LANGUAGE OF ALCHEMY THE DEGENERACY OF ALCHEMY PARACELSUS, AND SOME OTHER ALCHEMISTS SUMMARY OF THE ALCHEMICAL DOCTRINE THE REPLACEMENT OF THE THREE PRINCIPLES OF THE ALCHEMISTS BY THE ... movements of minute particles; and this was the central idea of the atomic theory of the Greek philosophers The atomic theory was used by the great physicists of the later Renaissance, by Galileo, ... that are of mortal body." The first -beginnings, or atoms, of things were thought of by Lucretius as always moving; "there is no lowest point in the sum of the universe" where they can rest; they...
Ngày tải lên: 28/06/2014, 19:20
annual report 1999 holderbank by accelerating the construction of new cement plants and kiln lines we aim to strengthen market and cost leadership and enhance environmental efficiency
... Schmidheiny Markus Akermann The term of office for all members of the Board of Directors expires on the day of the 2002 General Meeting of Shareholders The Area Managers and the CEO of “Holderbank” Management ... consolidat- further enhanced by the takeover of cement ed in the second half of 1998, merged with terminals on several islands of the eastern Juan Minetti at the beginning of 1999 Caribbean The five ... capable of loading 1,200 tonnes in The local winegrowers’ cooperative is justifi- just 75 minutes; on the other, there is the ably proud of its harvest: their quality has natural environment of vineyards...
Ngày tải lên: 27/07/2014, 16:07
Báo cáo y học: " b-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryo" docx
... output The induction of apoptosis of the endocardium and erythrocytes by b-lapachone is mediated through an NQO1- and calcium-dependent pathway This study further demonstrated the importance of the ... by co-incubation of b-lapachone with either dicoumarol, an NQO1 inhibitor, or BAPTAAM, a Ca2+ chelator (Figure 5) These results indicate that the induction of cell death of erythrocytes and the ... in both erythrocytes and the endocardium of b-lapachone-treated embryos Furthermore, we demonstrated that the induction of apoptosis of the endocardium and erythrocytes by b-lapachone is mediated...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of" ppt
... associated with the expression of pro-inflammatory cytokines To determine whether the inhibition of IL-6 and IL-8 expression was mediated by inhibition of MAPK, we examined the effect of POMx on the activation ... glands, resulting in the recruitment of activated immune and inflammatory cells to the site of inflammatory lesion, thereby amplifying and sustaining the inflammatory condition [8] The pro-inflammatory ... μg/ml of POMx significantly decreased the PMACI-induced IL-6 and IL-8 production in the culture supernatant of activated KU812 cells Effect of POMx on the activation of MAPK Activation of MAPKs...
Ngày tải lên: 11/08/2014, 08:22
báo cáo khoa học: " Ethylene is involved in pistil fate by modulating the onset of ovule senescence and the GA-mediated fruit set in Arabidopsis" docx
... patterns of genes of the ethylene biosynthesis and GUS activity in the ACS2:GUS line closely matched the unfertilised ovule senescence [4] In view of the fact that the up-regulation of those genes of ... degradation of all tissues in the ovule Despite all this evidence, the independence of the pistil responsiveness to GA of the ovule fate cannot be completely ruled out Elucidation of the location of the ... consequently, the window of GA fruit set responsiveness Therefore, the final parthenocarpic fruit length would depend on the number of viable ovules present in the pistil at the time of GA treatment...
Ngày tải lên: 11/08/2014, 11:20
báo cáo khoa học: " Identification of novel maize miRNAs by measuring the precision of precursor processing" ppsx
... sequences of known miRNAs of other species [31-34] Out of the 84 unique miRNA sequences, 49 can be confirmed by our sequencing Table Summary of small RNA sequencing No of reads No of unique No of unique ... library The expressions of the newly identified miRNAs were validated by Northern blot using RNAs from kernel of mixed stages (Figure 4) As additional evidence to support the annotation of some of these ... satisfy the following: the MFEI [32](minimum free energy calculated by RNAfold divided by the sequence length) should ≤-0.15; the miRNA candidates should be on the stem of the stem-loop sequences; the...
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27kip1 in rats" ppsx
... Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European ... in the process of chronic hypoxia-induced pulmonary artery remodeling, the lysates of each group of PASMCs were used to WB assays As the results showed, compared with the normoxia group, the ... [3,8] Media hyperplasia is the main pathologic change of the remodeling pulmonary arteries The nature of the structural alteration and the mechanisms responsible for the pulmonary vasculature...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: "Mutations in matrix and SP1 repair the packaging specificity of a Human Immunodeficiency Virus Type 1 mutant by reducing the association of Gag with spliced viral RN" ppsx
... base-pairing of the DIS of two RNA molecules is a major determinant in the selection of the copackaged RNA partners, and the identity of the DIS plays an important role in the copackaging of RNAs ... with the reduced production of infectious virions, thereby reducing the overall infectivity of the virus In support of this hypothesis, we found that the compensatory mutations did not rescue the ... of MA (data not shown) We then determined the infectious titer of the virus, normalized against the amount of p24, to quantify the production of infectious virus by the mutants NLΔSL1 produced...
Ngày tải lên: 13/08/2014, 01:20
Integrating process planning and scheduling by exploring the flexibility of process planning
... by CFR Figure 7.13 The comparison of four rules by production cost increase Figure 7.14 The comparison of four rules by production time increase vi List of Tables Table 4.1 Machine database of ... operation of Job‘j’ 33 Chapter The Facilitator for Integration StartT(j, k) – The starting time of the ‘k’th operation of Job‘j’ EndT(j, k-1) – The ending time of the ‘k-1’th operation of Job‘j’ ... to their order in the sequence For each operation of the job Assign the operation to the machine in the available time slot No Last operation of job? Yes No All jobs assigned? Yes Output the...
Ngày tải lên: 08/11/2015, 16:30
Requirements elicitation driven by interviews the use of viewpoints (1996)
... that the tool offers two feedback mechanisms: one at the time the auestion is beinq annotated and the other as the interview ends, At the 86 Proceedings of the 8th International Workshop on Software ... deals with the interface, the order of questions and heuristic’s application Heuristics are activated by a particular question or by the end of the interview The questions are based on the conceptual ... for other entity defined and the arcs the relationships among the information The nodes serve as basis for the questions posed by the assistant The arcs provide relationships that will help the...
Ngày tải lên: 15/01/2016, 16:29