history of small cell lung cancer icd 9 code

... survival of patients with lung cancer in Europe, 1985-1989. EUROCARE Working Group. Eur J Cancer 1998, 34:2191-2196. 3. Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, Thun MJ: Cancer statistics, ... non- small-cell lung cancer. J Clin Oncol 1999, 17:2692-2699. 19. Martel MK, Ten Haken RK, Hazuka MB, Kessler ML, Strawderman M, Turrisi AT, Lawrence TS, Fraass BA, Lichter AS: Estimation of tumor ... Feasibility of escalating daily doses of cisplatin in combination with accelerated radi- otherapy in non-small cell lung cancer. Eur J Cancer 1996, 32A:1314-1319. 7. Uitterhoeve AL, Belderbos JS,

Ngày tải lên: 09/08/2014, 10:21

... 157,300 deaths from lung cancer [4]. Lung cancer has traditionally been dichotomized into two groups based on the histological features of the tumor: small cell and non-small cell lung cancer. NSCLC ... non-small cell lung cancer comprise the majority of cases annotated within the database. Other cancers contained in the database include small cell lung cancer, mesothelioma, esophageal cancer, ... common of the two sub-types of lung cancer, constituting 85% of cases [5,6]. Further- more, studies have shown that NSCLC has less of a cau- sal association with smoking than other forms of lung cancer

Ngày tải lên: 10/08/2014, 09:22

... analysis of miR-451 expression in A549, A549/miR-NC or A549/miR-451 cells B Conventional stem-loop RT-PCR analysis of miR-451 expression in A549, A549/miR-NC or A549/ miR-451 cells Gel images of electrophoresis ... cytometry analysis of apoptosis in mock A549, A549/miR-NC or A549/miR-451 cells B Hoechst staining analysis of apoptosis in mock A549, A549/miR-NC or A549/ miR-451 cells C Analysis of relative caspase-3 ... 2010, 9:2742-2748 doi:10.1186/1756-9966-30-20 Cite this article as: Bian et al.: Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549) Journal

Ngày tải lên: 10/08/2014, 10:21

... Non-small cell lung cancer (NSCLC), which accounts for approximately 85% of all cases of lung cancer, will cause an estimated 161,840 deaths in the United States in 2008 [1] Approximately 70% of ... an estimated 15% of all new cancer cases diagnosed in the United States in 2008, and is responsible for an estimated 29% of all cancer deaths [1] World-wide, the impact of lung cancer is enor-mous, ... Abstract Lung cancer is the leading cause of cancer deaths world-wide Recent advances in cancer biology have led to the identification of new targets in neoplastic cells and the development of novel

Ngày tải lên: 10/08/2014, 22:20

... previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial Lancet 2008, 372(9652):1809-1818. 30 Park K, Goto K: A review of the benefit-risk profile of gefitinib in Asian ... Phase III Trial of Erlotinib Hydrochloride (OSI-774) Combined With Carboplatin and Paclitaxel Chemotherapy in Advanced Non-Small-Cell Lung Cancer J Clin Oncol 2005, 23(25):5892-5899. 16 Gatzemeier ... EGFR-related markers as potential predictors of the cetuximab benefit in 1st line advanced non-small cell lung cancer: results from the BMS099 study Journal of Thoracic Oncology 2008, 3(11):S304.

Ngày tải lên: 10/08/2014, 22:21

... IPAM e.V, Alter Holzhafen 19, 23966 Wismar, Germany Full list of author information is available at the end of the article Trang 2Lung cancer is the leading cause of cancer death in men and the ... rate will surpass breast cancer mortality rate before 2030 in many countries [3] Non-small cell lung cancer (NSCLC) accounts for approxi-mately 85% of all diagnosed lung cancer cases [4] The 5-year ... Background: The objective of this study was to describe the real-world treatment and overall survival (OS) of German patients with a diagnosis of advanced non-small cell lung cancer (aNSCLC), and

Ngày tải lên: 17/06/2020, 11:28

... effects of siRNA-mediated knockdown of CHD4 on the proliferation of A459 and H1299 cells determined by MTT assay c Representative results of the cell cycle analyses by FACS CHD4 arrested the cell ... expression of PHF5A in A549 cells, and Fig 3 The effects of CHD4 up-regulation on NSCLC cell proliferation and migration a Detection of over-expression of the CHD4 gene in H292 and PC-9 cells by ... effects of over-expression of CHD4 on the proliferation of H292 and PC-9 cells by MTT assay c Representative results of transwell migration assays in CHD4-overexpressing H292 and PC-9 cells at

Ngày tải lên: 17/06/2020, 11:36

... number:NCT01494558 (Registered 19 December 2011) Keywords: Locally advanced, Non-small-cell lung cancer, ECOG 2, Chemoradiotherapy, Efficacy, Toxicity Background Non-small-cell lung cancer (NSCLC) ... study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer J Clin Oncol 1999;17(9):2692 ... and quality of life benefits in poor prognosis stage III non-small-cell lung cancer: a randomised trial by the Norwegian lung Cancer study group Br J Cancer 2013;109(6):1467 –75. 19 Bi N, Wang

Ngày tải lên: 17/06/2020, 11:38

... for PD-L1-positive non-small-cell lung Cancer N Engl J Med 2016;375(19):1823 –33. 4 Remon J, Vilarino N, Reguart N Immune checkpoint inhibitors in non-small cell lung cancer (NSCLC): approaches ... prediction of both eligible tar-gets for irradiation and probable lesion of abscopal response Characteristics of participants One hundred thirty patients with metastatic non-small cell lung cancer ... subsets of Trang 8immune cells To this end, tissue slides will be subjectedto a panel of IHC markers capable of identifying various types of immune cells Depending on the availability of tumor

Ngày tải lên: 17/06/2020, 18:37

... R T I C L E Open AccessInvestigation of the key chemical structures involved in the anticancer activity of disulfiram in A549 non-small cell lung cancer cell line Kate Butcher1†, Vinodh Kannappan1†, ... chemoresistance in resistant cancer cell lines [9–11, 13] Its cytotoxicity in cancer cells is copper dependent [8, 9, 19] Although DS shows high in vitro toxicity in cancer cells, there was almost ... the cytotox-icity of DS in cancer cells [19, 24] The role of the thiuram structure and ethyl groups in the cytotoxicity of DS in cancer cells is still not clear Elucidation of the relationship

Ngày tải lên: 03/07/2020, 01:05

... proliferation of A549 and H1993 cells whether followed by X-ray irradiation or not The combined treatment of MβCD and radiation resulted in additive increases in apoptosis of A549 and H1993 cells In ... proliferation of human NSCLC cell lines A549 and H1993 with or without X-ray irradiation, and the combination of MβCD and radiation resulted in additive increases in the apoptosis of A549 and H1993 cells ... radio-resistance of NSCLC cells Methods Cell lines, reagents and instruments Human NSCLC cell line A549 (catalogue number: TCHu150) was obtained from the Cell Bank of the Chinese Academy of Sciences and H1993

Ngày tải lên: 24/07/2020, 01:11

... 0.9567 yes 1469(55.58) 788(55.53) 681(55.64) Family history of NSCLC none 2494(94.36) 1324(93.31) 1170(95.59) 0.0112 have 149(5.64) 95(6.69) 54(4.41) primary lesion site left 1051(39.77) 560(39.46) ... stage I non-small cell lung Cancer Anticancer Res 2015;35(7):4243 –9. 19 Potosky AL, Saxman S, Wallace RB, Lynch CF Population variations in the initial treatment of non-small-cell lung cancer J ... 0.701, 95%CI 0.510–0.962), or to receive ACT (OR = 0.627, 95%CI 0.450–0.873), PORT (OR = 0.129, 95%CI 0.036–0.469) and radiographic assessment of chemotherapy response (OR = 0.627, 95%CI 0.441–0.893)

Ngày tải lên: 24/07/2020, 01:47

... Afatinib 85,802 1.69 2.59 1.18 119,048 30% reduction PemCis 69,583 1.58 2.45 0.68 Afatinib 81,724 1.69 2.59 1.18 109,747 40% reduction PemCis 66,534 1.58 2.45 0.68 Afatinib 77,646 1.69 2.59 1.18 100,447 ... Dedication waiver Trang 2Lung cancer is one of the most common cancers diag-nosed in adults in Singapore, accounting for approxi-mately 11% of all cancers and 22% of cancer-related deaths from ... study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy Lung Cancer 2012;75:82 –8. 15 Rohatgi A WebPlotDigitizer Version 3.9 http://arohatgi.info/

Ngày tải lên: 24/07/2020, 02:00

... K Quality of life and survival survey of cancer cachexia in advanced non-small cell lung cancer patients-Japan nutrition and QOL survey in patients with advanced non-small cell lung cancer study ... Takahashi T, Yamamoto N Prognostic impact of cancer cachexia in patients with advanced non-small cell lung cancer Support Care Cancer 2015;23:1699 –708. 9 Crawford J, Prado CM, Johnston MA, Gralla ... Keywords: Non-small-cell lung cancer, Elderly, Cancer cachexia, Activity of daily living, Length of hospital stay, Medical cost Background The number of elderly people living with advanced lung cancer

Ngày tải lên: 06/08/2020, 03:21

... cohort of 3556 patients diagnosed with non-squamous non-small cell lung cancer in northern New Zealand between 1 Feb 2010 and 31 July 2017 A total of 1694 patients were tested forEGFR mutations, of ... University of Auckland, B507, 22-30 Park Ave, Grafton, Auckland 1072, New Zealand Full list of author information is available at the end of the article Trang 2Non-small cell lung cancer (NSCLC) ... systemic chemotherapy in non-small cell lung cancer (NSCLC) patients withEGFR gene mutations Detection ofEGFR mutations is a challenge in many patients due to the lack of suitable tumour specimens

Ngày tải lên: 06/08/2020, 05:46

... non-small cell lung cancer (NSCLC), as well as the underlying mechanisms Methods: The effect of overexpression of miR-146a and/or knockdown of cyclin J (CCNJ) in A549/DDP and SPC-A1/ DDP cells ... A549/DDP and SPC-A1/DDP cells Overexpression of miR-146a enhanced the in vivo sensi-tivity of A549/DDP cells to DDP To further confirm the effects of miR-146a on the che-mosensitivity of A549/DDP ... ana-lyzed the effects of miR-146a on cell cycle and apop-tosis of A549/DDP and SPC-A1/DDP cells by flow cytometry Compared with A549/DDP/NC and SPC-A1/DDP/NC cells, the percentage of G0/G1 phase was

Ngày tải lên: 20/09/2020, 01:30

... polymerase chain reaction, Non-small cell lung cancer, Tyrosine kinase inhibitors * Correspondence: guxia1373@163.com 1 Department of Pathology, the First Affiliated Hospital of Guangzhou Medical University, ... the 40 % of the tumor cells (Fig 1f ) Twenty-three of these cases underwent EGFR muta-tion detecmuta-tion, and 17 of them were confirmed as EGFR mutation (8 with exon 19 deletion and 9 with exon ... R C H A R T I C L E Open AccessComparison of detection methods and follow-up study on the tyrosine kinase inhibitors therapy in non-small cell lung cancer patients with ROS1 fusion rearrangement

Ngày tải lên: 20/09/2020, 15:04

... between 1 and 30 % of the cells Considering FISH as the reference method, the sensitivity of the Ventana CDx Assay was 69.2 % with a specificity of 99.3 % and an accuracy of 99 % (Fig 2b) Comparison ... FISH by IHC Background Lung cancer is the leading cause of death due to cancer worldwide [1] The disease comprises histologically dif-ferent entities where non-small cell lung cancer (NSCLC) presents ... as the reference method the sensitivity of the in house IHC assay was 61.5 % with a specificity of 99.6 % and an accuracy of 98.9 % (Fig 2c) The results of the comparisons between FISH and both

Ngày tải lên: 20/09/2020, 15:18

... of 11 tumors with squamous cell carcinoma had a maximum tumor diameter <3 cm (81.8 %) On the other hand, 68 of 69 adenocarcinomas had a maximum tumor diameter <3 cm (98.6 %), and 6 of 9 ... Abstract Background: To investigate the prognostic value of oligo-recurrence in patients with brain-only oligometastases of non-small cell lung cancer (NSCLC) treated with stereotactic radiosurgery ... median OS of 18 months (95 % CI: 14.8–21.1 months) and a 5-year OS of 0 %, while the oligo-recurrence group achieved a median OS of 41 months (95 % CI: 27.8–54.2 months) and a 5-year OS of 18.6

Ngày tải lên: 20/09/2020, 15:26

... Trang 2Lung cancer is the primary cause of cancer related death in the developed world, accounting for 12 % of deaths worldwide [1] The majority of patients with advanced non-small cell lung cancer ... survival rate of just 15 % [3] Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths in men and women, com-prising approximately 80–85 % of all lung cancers [4] Baicalein, ... reduc-tion in cell number can be seen compared to control cells and cells treated with the other two concentra-tions (891 ± 286.6 cells 10 μM baicalein vs 3414 ± 300 cells untreated; 989 ± 89.4 cells

Ngày tải lên: 20/09/2020, 17:55