head and neck squamous cell carcinoma prognosis

... immunotherapies in head and neck squamous cell carcinoma Oral oncology 2013; 49: 1089-96 Deng WW, Wu L, Sun ZJ Co-inhibitory immune checkpoints in head and neck squamous cell carcinoma Oral Dis ... derivative, VdiE-2N, in head and neck squamous cell carcinoma European journal of pharmacology 2018; 819: 198-206 Leemans CR, Braakhuis BJ, Brakenhoff RH The molecular biology of head and neck cancer Nature ... indicator and correlated with the immunosuppression of tumor microenvironment Key words: LAMTOR5, head and neck squamous cell carcinoma, prognosis, immunohistochemistry, knockout mice Introduction Head

Ngày tải lên: 15/01/2020, 18:14

... radiotherapy in head and neck cancer: a meta-analysis Lancet 2006, 368:843-854. 7 Lee N, Puri DR, Blanco AI, Chao KS: Intensity-modulated radiation therapy in head and neck cancers: an update Head Neck ... pathologically and reviewed within the multidis-ciplinary head-and-neck team As part of the study, the imaging of the all patients who experienced LRR was reviewed by a head and neck specialist ... Karen Dyker1, Catherine Coyle1and Mehmet Sen1* Abstract Background: To establish recurrence patterns among locally advanced head and neck non-nasopharyngeal squamous cell carcinoma (HNSCC) patients

Ngày tải lên: 09/08/2014, 09:20

... signaling networks for head and neck squamous cell carcinoma Gurkan Bebek1,3,4, Mohammed Orloff1,2and Charis Eng1,2,4,5* Abstract Background: Advanced stage head and neck squamous cell carcinoma (HNSCC) ... and genes that are germane to HNSCC Background HNSCC is the sixth most common cancer and remains a major cause of cancer morbidity and mortality worldwide [1] More than 85% of head and neck squamous ... microdissection, epithelium and stromal tissue compartments of squamous cell cancer lesions of head and neck from 122 samples were acquired. Table 2 Hot spot-, cold spot- and clinicopathological

Ngày tải lên: 10/08/2014, 09:22

... comparable to other cancer cells, e.g cervical adenocarcinoma cells [43], osteosarcoma cells [42], lung adenocarcinoma cells [37,41], and gastric and colon cancer cells [44] Despite this, nanoparticle ... nanoparticles, silica dioxide, surface properties, tumor cell line, uptake, endocytosis, cellular fate Introduction Head and neck squamous cell carcinoma (HNSCC) comprise a group of epithelial cancers ... Nano ZS, Malvern Instruments Ltd., UK) 2.2 Cell Culture The head and neck squamous carcinoma cell line UMBSCC-745 was kindly provided by Dr Robert Mandić, Department of Otolaryngology, Philips

Ngày tải lên: 11/08/2014, 00:23

... distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma Addresses: * Head and Neck Surgery Branch, ... specimen; SCC, squamous cell carcinoma; S, surgery; TNM, tumor-node-metastasis (staging system); UM-SCC, University of Michigan series head and neck squamous cell carcinoma Trang 4p53 genotype and protein ... UM-SCC cell linesFigure 1 p53 genotype and protein expression in UM-SCC cell lines (a) The p53 genotype of ten University of Michigan series head and neck squamous cell carcinoma (UM-SCC) cell

Ngày tải lên: 14/08/2014, 07:21

... Lymphovascular invasion, Head and neck squamous cell carcinoma, Hub genes, TCGA, Weighted gene co-expression network analysis Background Head and neck squamous cell carcinoma (HNSCC) is one of the most ... cancers with high morbidity and mortality rates worldwide; > 90% of head and neck cancers are squamous cell carcinomas that arise in the oral cavity, oropharynx, and larynx [1] Metastasis is ... in head and neck squamous cell carcinoma Jian Zhang1†, Huaming Lin2†, Huali Jiang3†, Hualong Jiang4†, Tao Xie1, Baiyao Wang1, Xiaoting Huang1, Jie Lin1, Anan Xu1, Rong Li1, Jiexia Zhang5*and

Ngày tải lên: 17/06/2020, 11:24

... JC, et al Potentially novel candidate biomarkers for head and neck squamous cell carcinoma identified using an integrated cell line-based discovery strategy Mol Cell Proteomics 2012;11(11):1404 ... molecular signatures in head and neck squamous cell carcinoma Fatima Qadir1, Anand Lalli1, Huma Habib Dar1, Sungjae Hwang1, Hebah Aldehlawi1, Hong Ma2, Haiyan Dai2, Ahmad Waseem1and Muy-Teck Teh1,2,3* ... better prognosis in gastric cancer patients but poorer prognosis in breast, lung and liver cancer patients Trang 8regulated in salivary ductal carcinoma [28], oesophagealsquamous cell carcinoma

Ngày tải lên: 17/06/2020, 17:43

... classification update Revisions proposed by American Head and Neck Society and the American Academy of Otolaryngology Head and Neck Surgery Arch Otlolaryngol Head Neck Surg 2002;128:751–8 Gregoire V, Eisbruch ... therapy (65 % vs 48 %, p = 0.04), and the postoperative radiation therapy has been a standard of care for patients with advanced resectable head and neck squamous cell carcinoma (HNSCC) Nevertheless, ... midline, and existence of ECS Results: Seventy-two patients were identified who were treated with postoperative radiation therapy for head and neck squamous cell carcinoma between November 2005 and

Ngày tải lên: 21/09/2020, 09:19

... NCT01081041; date of registration: March 3, 2010) Keywords: Carcinoma, squamous cell, Cetuximab, Head and neck cancer, Safety Background Head and neck cancer is the sixth most common cancer worldwide, ... RT: randomized and treated; SCCHN: squamous cell carcinoma of the head and neck; TEAE: treatment-emergent adverse event; US: United States Page of 10 Competing interests KB, SH, CKO, S-CC, and ... carboplatin and fluorouracil in patients with recurrent or metastatic squamous cell carcinoma of the head and neck J Clin Oncol 2006;24:2866–72 Submit your next manuscript to BioMed Central and we

Ngày tải lên: 21/09/2020, 11:15

... cancer Background Head and neck carcinomas arise in the mucosal layer of the upper aerodigestive tract (oral cavity, oropharynx, hypopharynx, and larynx) Nearly 90 % of head and neck carcinomas are ... Fifty-seven paired pieces of head and neck squamous cell carcinoma (HNSCC) and adjacent non-cancerous tissue (ANCT) were compared for their mRNA levels for ACh-related proteins and ACh-hydrolyzing activity ... prognostic in patients with head and neck squamous cell carcinoma Ana Cristina Castillo-González1†, Susana Nieto-Cerón1†, Juan Pablo Pelegrín-Hernández2, María Fernanda Montenegro3, José Antonio

Ngày tải lên: 30/09/2020, 10:56

... therapy Keywords: HNSCC (head & neck squamous cell carcinoma), Stem-like cells, CD24, CD44, Salivary gland malignant neoplasms Background Squamous cell carcinoma of head and neck (HNSCC) is a heterogeneous ... growth, and invasion of cancer are driven by a small population of cancer stem cells (CSC) Previous studies have identified CD44+ cells as cancer stem cells in head and neck squamous cell carcinoma ... L E Open AccessIdentification and characterization of cancer stem cells in human head and neck squamous cell carcinoma Jing Han1, Toshio Fujisawa2, Syed R Husain1and Raj K Puri1* Abstract Background:

Ngày tải lên: 05/11/2020, 01:35

... induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt Abstract Background: Cancer stem cells ... determine the effects of salinomycin on head and neck squamous cell carcinoma (HNSCC) stem cells Methods: MTS and TUNEL assays were used to study cell proliferation and apoptosis as a function of salinomycin ... extend our understanding of salinomycin’s therapeutic properties in head and neck squamous cell carcinoma (HNSCC) stem cells We aim to determine whether salinomycin, alone and in combination

Ngày tải lên: 05/11/2020, 07:53

... represses PTEN and is over-expressed in head and neck squamous cell carcinoma Durmus Burgucu1, Kenan Guney2, Duygu Sahinturk3, Irem Hicran Ozbudak4, Deniz Ozel5, Gulay Ozbilim4 and Ugur Yavuzer1* ... diagnostic and treatment strategies, head and neck squamous cell cancer (HNSCC) constitutes one of the worst cancer types in terms of prognosis PTEN is one of the tumour suppressors whose expression and/or ... expressed in HNSCC and may repress PTEN, thus leading to cancer formation and/or progression Methods: Using immunohistochemistry and quantitative PCR (qPCR), protein and mRNA levels of PTEN and Tbx3 were

Ngày tải lên: 05/11/2020, 09:18

... Photochemotherapy To Head And Neck Squamous Cell Carcinoma Alp Yurter Follow this and additional works at: https://elischolar.library.yale.edu/ymtdl This Open Access Thesis is brought to you for free and open ... Application to Head and Neck Squamous Cell Carcinoma 5 STATEMENT OF PURPOSE 8 Specific Aims 8 Hypothesis 8 MATERIALS AND METHODS 9 HPV16 E7 Antigen Sources 9 Peripheral Blood Mononuclear Cells (PBMCs) ... controls.4 Potential Application to Head and Neck Squamous Cell Carcinoma To test ECP’s efficacy in other solid tumors, we sought a malignancy with poor prognosis and easily trackable antigens to

Ngày tải lên: 27/02/2022, 06:33

... therapy Keywords: HNSCC (head & neck squamous cell carcinoma), Stem-like cells, CD24, CD44, Salivary gland malignant neoplasms Background Squamous cell carcinoma of head and neck (HNSCC) is a heterogeneous ... growth, and invasion of cancer are driven by a small population of cancer stem cells (CSC) Previous studies have identified CD44+ cells as cancer stem cells in head and neck squamous cell carcinoma ... L E Open AccessIdentification and characterization of cancer stem cells in human head and neck squamous cell carcinoma Jing Han1, Toshio Fujisawa2, Syed R Husain1and Raj K Puri1* Abstract Background:

Ngày tải lên: 02/11/2022, 11:41

... Akhilesh Pandey12,13,14,15, Harsha Gowda1,8 & Aditi Chatterjee1,8 Despite advances in clinical management, 5-year survival rate in patients with late-stage head and neck squamous cell carcinoma ... therapeutic target in HNSCC. Squamous cell carcinoma of head and neck (SCCHN) is a common malignancy worldwide arising from var-ious regions of upper-aero digestive tract and oral cavity It is the ... positive and PI negative), compared to 3.7% late apoptotic cells and 1.7% of early apoptotic cells in the control (DMSO treated) cells (Fig. 5a) In JHU-O28 cells harmine treatment induced 10.8% and

Ngày tải lên: 08/11/2022, 14:58

... Wu3†and Michael Hsiao1,2,10*† Abstract Background: Head and neck squamous cell carcinoma (HNSCC) represents a unique and major health concern worldwide Significant increases in glucose uptake and ... downregulation Methods Cell culture and stable clone establishment The human head and neck squamous cancer cell lines FaDu, Detroit-562, HSC-2, HSC-3, HSC-M3, HSC-4, RPMI-650, and Ca-922 were grown ... was 190 months Over-all survival and disease-free survival were defined as the intervals from surgery to death caused by head and neck squamous cell carcinoma and recurrence or distant me-tastasis,

Ngày tải lên: 04/12/2022, 10:32

... Trang 2Head and neck squamous cell cancer (HNSCC) is the sixth most prevalent form of cancer It has a high inci-dence worldwide, and 90% of cases are histologically identified as squamous cell carcinomas ... in head and neck squamous cell carcinomas Head Neck 2006;28(9):813 –8. 13 Huang CF, Zhang L, Ma SR, Zhao ZL, Wang WM, He KF, Zhao YF, Zhang WF, Liu B, Sun ZJ Clinical significance of Keap1 and ... in oral squamous cell carcinoma PLoS One 2013;8(12):e83479. 14 The Cancer Genome Atlas Network (348 collaborators) Comprehensive genomic characterization of head and neck squamous cell carcinomas.

Ngày tải lên: 23/07/2020, 23:49

... docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells Seok-Woo Park1†, ... proliferation of head and neck squamous cell carcinoma (HNSCC) cell lines in a receptor-independent manner In this study, using HNSCC cell lines, we examined the anti-cancer effects and the mechanisms ... 1 DHEA and NALA effectively inhibit cell proliferation and induce cell death in HNSCC cell lines a Cells were treated with 20 μM of DHEA, EPEA and NALA At 72 h, cells were subjected to cell proliferation

Ngày tải lên: 21/09/2020, 01:54

... Chemotherapy, Head and neck squamous cell carcinoma, Recommendations Background Head and neck carcinomas account for 5 % of all can-cers, and over 90 % are head and neck squamous cell carcinoma (HNSCC) ... Lertsanguansinchai11, Vijay Anand Reddy12and Xia He13 Abstract With increasing numbers of patients with unresectable locoregionally advanced (LA) head and neck squamous cell carcinoma (HNSCC) receiving ... the field of head and neck cancer management assembled for an Asia–Pacific head and neck cancer expert panel meeting in China The compilation of discussion outcomes of this meeting and literature

Ngày tải lên: 21/09/2020, 11:18