head and neck cancer cell lines hpv

... that affect cellular proliferation, apoptosis, angiogenesis, immune and proinflammatory responses, and therapeutic resistance in head and neck squa- mous cell carcinoma (HNSCC) and other cancers ... differentially expressed by head and neck cancer cell lines differing in p53 status. There were 748 NF- κ B targets predicted and individually annotated for RELA, NF κ B1 or cREL regulation, and a prevalence ... factor, and hepatocyte growth factor [18,34,37,39-42]. We recently identified specific gene expression signatures in HNSCC cell lines (UM-SCC, University of Michigan Cell Lines Series of Head and Neck

Ngày tải lên: 14/08/2014, 08:20

... smoking and the reversal of head and neck cancer risk. Int J Epidemiol 2010;39(1):182 –96. 5 Leemans CR, Braakhuis BJ, Brakenhoff RH The molecular biology of head and neck cancer Nat Rev Cancer ... Trang 2Head and neck squamous cell cancer (HNSCC) is the sixth most prevalent form of cancer It has a high inci-dence worldwide, and 90% of cases are histologically identified as squamous cell ... head and neck squamous cell cancer Akhileshwar Namani1†, Md Matiur Rahaman2†, Ming Chen2*and Xiuwen Tang1* Abstract Background: NRF2 is the key regulator of oxidative stress in normal cells and

Ngày tải lên: 23/07/2020, 23:49

... M, Sudhoff HH: HPV & head and neck cancer: a descriptive update Head Neck Oncol 2009, 1:36. 3 Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment ... identified CD24 as a marker in cancer stem cells in several cancers, including pancreatic cancer [11], colorectal cancer-derived cell lines [8], and ovarian cancer [9] Cancer stem cell immunophenotype ... growth, and invasion of cancer are driven by a small population of cancer stem cells (CSC) Previous studies have identified CD44+ cells as cancer stem cells in head and neck squamous cell carcinoma

Ngày tải lên: 05/11/2020, 01:35

... rate of head and neck cancer cells Fadu and SCC25 cell lines were transfected with miR-10b precursor and negative control (scramble) and the proliferation rate was measured for 72 hours A and C: ... miR-10b and miR-196a lead to im-paired cell proliferation Precursor molecules of miR-10b were transfected into SCC25 and SCC9 (tongue squamous cell carcinoma-derived cell lines) and FaDu (a cell ... considered in several human diseases and cancers [5,6] Head and neck squamous cell carcinoma (HNSCC) is a significant public health entity, representing the sixth lead-ing cancer by incidence worldwide

Ngày tải lên: 05/11/2020, 05:32

... M, Sudhoff HH: HPV & head and neck cancer: a descriptive update Head Neck Oncol 2009, 1:36. 3 Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment ... identified CD24 as a marker in cancer stem cells in several cancers, including pancreatic cancer [11], colorectal cancer-derived cell lines [8], and ovarian cancer [9] Cancer stem cell immunophenotype ... growth, and invasion of cancer are driven by a small population of cancer stem cells (CSC) Previous studies have identified CD44+ cells as cancer stem cells in head and neck squamous cell carcinoma

Ngày tải lên: 02/11/2022, 11:41

... proliferation abilities and resist cell death signals or growth suppressors Head and neck squamous cell carcinoma (HNSCC) ranks among the eighth of the leading cancers in the USA and is estimated to ... proliferation, and differentiation in endochondral bone formation process13,14 and is an important transcription factor in breast and prostate cancer development and progression15 In breast cancer cells and ... role of PTHLH in head and neck cancer by Figure 4 RUNX2 controls HNSCC cell growth (A and B) The in vitro proliferation (A) and in vivo tumor growth (B) abilities in of Ca9-22 cells without (EV)

Ngày tải lên: 04/12/2022, 15:59

... therapy for head and neck carcinoma The Oncologist 2007, 12:555-564. 2 Lee N, Puri D, Blanco AI, Chao KS: Intensity modulated radiathion therapy in head and neck cancers: an update Head and Neck 2007, ... head and neck cancers is feasible and effective, with acceptable toxicities Introduction Radiotherapy (RT), with or without chemotherapy, is the primary treatment modality for head and neck cancer ... radiation therapy of head and neck cancer Expert Rev Anticancer Ther 2008, 8:633-644. 4 Li Y, Ten Haken R, Eisbruch A: The impact of dose on parotid recovery in head and neck cancer patients treated

Ngày tải lên: 09/08/2014, 09:20

... radiotherapy in head and neck cancer: a meta-analysis Lancet 2006, 368:843-854. 7 Lee N, Puri DR, Blanco AI, Chao KS: Intensity-modulated radiation therapy in head and neck cancers: an update Head Neck ... preliminary results of a European Organization for Research and Treatment of Cancer phase III trial EORTC Head and Neck Cancer Cooperative Group J Natl Cancer Inst 1996, 88:890-899. 3 Induction chemotherapy ... pathologically and reviewed within the multidis-ciplinary head-and-neck team As part of the study, the imaging of the all patients who experienced LRR was reviewed by a head and neck specialist

Ngày tải lên: 09/08/2014, 09:20

... Radiotherapy for Locally Recurrent Head-and-Neck Tumors Int J Radiat Oncol Biol Phys 14 Langlois D, Eschwege F, Kramar A, Richard JM: Reirradiation of the head and neck cancers Radiother Oncol 1985, ... head and neck cancer with curative intent Int J Radiat Oncol Biol Phys 1994, 29:687-698. 16 Ohizumi Y, Tamai Y, Imamiya S, Akiba T: Prognostic factors ofreirradiation for recurrent head and neck ... 9610, a multi-institutional trial ofreirradiation and chemotherapy for unresectable recurrent squamous cell carcinoma of the head and neck Head Neck 2008, 30:281-8. 20 Sulman EP, Schwartz DL, Le

Ngày tải lên: 09/08/2014, 09:21

... Amsterdam, The Netherlands, 3 Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands, 4 Department of ... Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands and 5 Department of ORL, Academic Medical Center, Amsterdam, the Netherlands, Department of Head and Neck ... glands was removed in 53% of the cases, both submandibular glands in 12%, 6% had their superficial parotid gland removed another 6% had their superficial parotid gland and one submandibular gland

Ngày tải lên: 09/08/2014, 09:22

... with head and neck cancer Head Neck 2000, 22:474-82. 37 Stenson KM, MacCracken E, List M, Haraf DJ, Brockstein B, Weich-selbaum R, Vokes EE: Swallowing function in patients with head and neck cancer ... for head and neck carcinoma Oncologist 2007, 12:565-8. 5. Rosenthal DI, Lewin JS, Eisbruch A: Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer ... patients with head and neck cancer treated with radiotherapy J Clin Oncol 3776, 26:3770-2008. 32. Rosenthal DI, Trotti A: Strategies for managing radiation-induced mucositis in head and neck cancer

Ngày tải lên: 09/08/2014, 10:20

... simultaneously integrated boost (SIB) in head and neck cancer patients Address: 1 Department of Radiation Oncology, University Hospital, Zurich, Switzerland and 2 Department of Radiation Physics, ... boost (SIB) application in the head and neck region in terms of normal tissue response As known from 3DCRT, dose, fractionation and treated volumes are the tumor control and normal tissue tolerance ... (H-0022 and 0225)) have been pub-lished; to this date there is no universally agreed standard of dosage We found SIB 2.11 and SIB2.2 equally well tolerated and safe with respect to acute and late

Ngày tải lên: 09/08/2014, 10:20

... resistant) was measured in head and neck tumor cell lines [30] (GSE9714) and NCI Anti-Cancer Drug Screen (NCI60) cell lines [31] (GSE7505), only the stroma-associated genes (Table 3 and Additional File ... signaling networks for head and neck squamous cell carcinoma Gurkan Bebek1,3,4, Mohammed Orloff1,2and Charis Eng1,2,4,5* Abstract Background: Advanced stage head and neck squamous cell carcinoma (HNSCC) ... proteins and genes that are germane to HNSCC Background HNSCC is the sixth most common cancer and remains a major cause of cancer morbidity and mortality worldwide [1] More than 85% of head and neck

Ngày tải lên: 10/08/2014, 09:22

... resistance in breast and ovarian cancer cell lines Niels Eckstein Abstract Breast and ovarian cancers are among the 10 leading cancer types in females with mortalities of 15% and 6%, respectively. ... collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006, 10:515-27. 4. Wang D, Lippard SJ: Cellular processing of platinum anticancer drugs. Nature ... functional and biochemical changes after establishment of Cisplatin resistance is given. Cisplatin resistant breast cancer cells and ovarian cancer cells were compared to their non-resistant parental cells.

Ngày tải lên: 10/08/2014, 10:21

... References Tobias JS: Cancer of the head and neck Bmj 1994, 308:961-966 Amir Z, Kwan SY, Landes D, Feber T, Williams SA: Diagnostic delays in head and neck cancers Eur J Cancer Care (Engl) 1999, ... Harrison PR: Profiling early head and neck cancer Nat Rev Cancer 2005, 5:127-135 Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment Mayo Clin Proc 2008, ... concentrations comparable to other cancer cells, e.g cervical adenocarcinoma cells [43], osteosarcoma cells [42], lung adenocarcinoma cells [37,41], and gastric and colon cancer cells [44] Despite this,

Ngày tải lên: 11/08/2014, 00:23

... UM-SCC cell linesFigure 1 p53 genotype and protein expression in UM-SCC cell lines (a) The p53 genotype of ten University of Michigan series head and neck squamous cell carcinoma (UM-SCC) cell lines ... distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma Addresses: * Head and Neck Surgery Branch, ... four cell lines, namely UM-SCC 1, 6, 9, and 11A Mutation of p53 was detected in five cell lines, namely UM-SCC 5, 22A, 22B, 38, and 46 (Figure 1a) A mutation was also detected in UM-SCC 11B cells,

Ngày tải lên: 14/08/2014, 07:21

... Receptor In Squamous Cell Carcinoma Of the Head And Neck as a Target for a Novel Nanotherapeutic Drug Head And Neck-Journal for the Sciences And Specialties Of the Head And Neck 2009; 31: 475-81 ... smoking in never drinkers, and the risk of head and neck cancer: Pooled analysis in the international head and neck cancer epidemiology consortium Journal Of the National Cancer Institute 2007; 99: ... Multimodal treatment for head and neck cancer Surg Clin North Am 2009; 89: 43-52 Murphy BA, Gilbert J, Ridner SH Systemic and global toxicities of head and neck treatment Expert Rev Anticancer Ther 2007;

Ngày tải lên: 15/01/2020, 16:59

... knockout mice Introduction Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer globally, accounting for more than 95 % of head and neck cancers [1] With an annual new ... a new and promising approach for several cancers including head and neck cancer [18] With downregulation of antigen-processing and presentation, secretion of immunosuppressive cytokines, and recruitment ... of head and neck cancer Nature reviews Cancer 2011; 11: 9-22 Guan GF, Zhang DJ, Wen LJ, Xin D, Liu Y, Yu DJ, et al Overexpression of lncRNA H19/miR-675 promotes tumorigenesis in head and neck

Ngày tải lên: 15/01/2020, 18:14

... squamous cell carcinoma, Hub genes, TCGA, Weighted gene co-expression network analysis Background Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers with high morbidity and ... worldwide; > 90% of head and neck cancers are squamous cell carcinomas that arise in the oral cavity, oropharynx, and larynx [1] Metastasis is the main cause of treatment failure and an important ... in head and neck squamous cell carcinoma Jian Zhang1†, Huaming Lin2†, Huali Jiang3†, Hualong Jiang4†, Tao Xie1, Baiyao Wang1, Xiaoting Huang1, Jie Lin1, Anan Xu1, Rong Li1, Jiexia Zhang5*and

Ngày tải lên: 17/06/2020, 11:24

... NOK3, NOK16 and NOK376) and 10 HNSCC cell lines (SCC4, SCC9, SCC15, SCC25, SqCC/Y1, UK1, VB6, CaLH2, CaDec12 and 5PT) We identified 3 most significantly upregulated (PLAU, FN1 and CDCA5) and 3 most ... keratinocytes Mol Cancer 2010;9(1):45. 19 Waseem A, Ali M, Odell EW, Fortune F, Teh MT Downstream targets of FOXM1: CEP55 and HELLS are cancer progression markers of head and neck squamous cell carcinoma ... advances in oncological management (https://www.cancerresearchuk org/health-professional/cancer-statistics/statistics-by-can cer-type/head-and-neck-cancers) © The Author(s) 2019 Open Access This

Ngày tải lên: 17/06/2020, 17:43