geriatric patients with advanced cancer

... ranged from 31 to 64 years (Table 1) Patients The sample of patients for the present study consisted of 201 advanced cancer patients (146 female) To participate, patients needed to meet the following ... psychiatric pathology and hematological cancers The age of patients ranged from 27 to 89 years old Diagnoses included breast cancer (45.3%), colorectal cancer (20.9%), lung cancer (14.9%), and others (18.9%; ... Keywords: Cancer, Oncology, Depression, Symptom assessment, Physician-patient relations, Patient-centered care Background Depression is a common emotional experience in people with advanced cancer

Ngày tải lên: 10/01/2020, 13:19

... symptoms among patients with advanced cancer Methods: An open-label randomized phase II clinical trial with two intervention arms and one control group Patients with advanced cancer starting ... incurable cancers: breast cancer, platinum-resistant ovarian cancer, cervical cancer, endometrial cancer, neck and head cancer (after radiotherapy failure), castration-resistant prostate cancer, ... non-depressed patients with advanced cancer starting first-line palliative chemotherapy, the early provision of PC would be associated with lower rates of depressive symptoms compared to standard cancer

Ngày tải lên: 06/08/2020, 05:03

... comprehensive support system for both patients with advanced cancer and their FCs are warranted and can be derived from these findings Keywords: Advanced cancer, Cancer patients, Caregivers, Palliative ... set-tings (inpatients vs outpatients), care received (with or without PC), and KPS scores As there is a paucity of local data on palliative care needs in patients with ad-vanced cancer and FCs ... Participants characteristics The data consisted of 599 patients with advanced cancer and 599 FCs recruited Comparing advanced cancer pa-tients with FCs, the demographics of papa-tients appeared to

Ngày tải lên: 19/09/2020, 22:08

... predictive factors of this regimen in a larger cohort of Taiwanese patients with advanced BTC Methods Patients All patients with histologically confirmed BTC treated at the Chang Gung Memorial ... prognostic and predictive factors of this regimen in a cohort of Taiwanese patients with advanced BTC Methods: A total of 118 patients with histologically confirmed BTC treated at Chang Gung Memorial Hospital ... findings could provide physicians with more information to justify the clinical outcomes in patients with advanced BTC in real-world practice Keywords: Biliary tract cancer, Chemotherapy, Gemcitabine,

Ngày tải lên: 30/05/2020, 21:37

... out of all patients with NSCLC, patients with advanced disease stage were identified based on their tumor stage at the time of their lung cancer diagnosis Tumor staging was evaluated with respect ... Study Population patients aNSCLC patients who received a mutation test aNSCLC patients who did not receive a mutation test aNSCLC patients aNSCLC patients without a test or with negative test ... mutation-positive patients, out of all identified incident aNSCLC patients (19·3% of patients with a presumed negative test result, and 73·7% of patients without testing) Among all incident aNSCLC patients,

Ngày tải lên: 17/06/2020, 11:28

... the survival of patients with advanced gastric cancer However, whether triplet chemotherapy can further improve the survival of patients with advanced gastric cancer compared with doublet chemotherapy ... combined with chemotherapy is approved, with only about 10% of patients experiencing HER2 overexpression [7] Chemotherapy can improve the survival of patients with advanced gastric cancer Compared with ... OS of patients with untreated advanced gastric cancer compared with cisplatin plus S1 regimen [12] Hence, whether triplet or doublet chemotherapy improves the survival of patients with advanced

Ngày tải lên: 17/06/2020, 19:11

... inpatient medical costs among elderly patients with advanced non-small-cell lung cancer (NSCLC) receiving chemotherapy Methods: Thirty patients aged ≥70 years with advanced NSCLC (stage III-IV) scheduled ... cancer treatments [1] In Japan, 65% of lung cancer morbidity cases and 73% of lung cancer-related deaths were attributed to elderly individuals aged ≥70 years in 2012 [2] Patients with lung cancer, ... trials Patients with cancer cachexia have poor physical function [13] and are at high risk for disabilities, prolonged hospitalizations, and in-hospital death [14] As a result, patients with cancer

Ngày tải lên: 06/08/2020, 03:21

... 78 patients with advanced gastric cancer who had undergone gastrectomy with or without combination of docetaxel, cisplatin and S-1 (DCS) as preoperative chemotherapy between 2005 and 2014 The patients ... tumor of gastric cancer patients who treated with preoperative or postop-erative chemotherapy Methods Inclusion and exclusion criteria Seventy-eight patients with advanced gastric cancer who had ... extravasated platelet aggregation as a surrogate marker for overall survival in patients with advanced gastric cancer treated with preoperative docetaxel, cisplatin and S-1: a retrospective observational

Ngày tải lên: 06/08/2020, 07:46

... BMC Cancer (2016) 16:480 DOI 10.1186/s12885-016-2510-z RESEARCH ARTICLE Open Access Serum fibrinogen levels are positively correlated with advanced tumor stage and poor survival in patients with ... gastric cancer (GC) patients The primary aim of this study was to evaluate the usefulness of preoperative serum fibrinogen as a biomarker for predicating tumor progression and survival of patients with ... This study included 1196 patients (885 males and 311 females) with GC, more than half of whom had advanced GCs Radical lymph node dissection was performed in 71.6 % of these patients MST was 41.9

Ngày tải lên: 20/09/2020, 14:10

... AccessPhase II study on first-line treatment of NIVolumab in combination with folfoxiri/ bevacizumab in patients with Advanced COloRectal cancer RAS or BRAF mutated – NIVACOR trial (GOIRC-03-2018) Angela ... Mohelnikova-Duchonova B, et al G12V and G12A KRAS mutations are associated with poor outcome in patients with metastatic colorectal cancer treated with bevacizumab Tumour Biol 2016;37:6823 –30. 5 Sorich MJ, ... pembrolizumab in combination with mFOLFOX6 for patients with advanced colorectal cancer J Clin Oncol 2017;35(15):3541. Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims

Ngày tải lên: 28/09/2020, 09:27

... BMC Cancer (2015) 15:339 DOI 10.1186/s12885-015-1350-6 RESEARCH ARTICLE Open Access Phase II study of axitinib with doublet chemotherapy in patients with advanced squamous non–small-cell lung cancer ... 85% of all lung cancers [1] Patients with NSCLC typically present with locally advanced or metastatic disease at the time of diagnosis [2], and in these cases prognosis is poor, with a 5-year survival ... axitinib in combination with cisplatin and gemcitabine in chemotherapy-naïve patients with advanced/metastatic squamous NSCLC Methods Patient selection Patients aged ≥18 years with histologically

Ngày tải lên: 29/09/2020, 16:21

... post-treatment prostatic biopsies from patients with advanced hormone-naive prostate cancer treated with docetaxel chemotherapy and androgen deprivation therapy (ADT) with an aim to identify the mechanisms ... in patients with hormone-nạve high-risk prostate cancer) study by Newcastle upon Tyne Hospitals National Health Service (NHS) Foundation Trust [15] All patients with a clin-ical suspicion of advanced ... transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer BMC Cancer 2014 14:977. Submit your next manuscript to BioMed Central and take

Ngày tải lên: 30/09/2020, 13:28

... pathways in patients with advanced cancer Clin Cancer Res 2012, 18(8):2316 –2325. 35 Leong S, Messersmith WA, Tan AC, Eckhardt SG: Novel agents in the treatment of metastatic colorectal cancer Cancer ... be synergistic in combination with fluoropyrimidine-based chemotherapy in patients with advanced colorectal cancer Moreover, other authors have shown that, compared with wild type tumors, tumors ... assess the predictive role of miRNA expression profiles in patients with advanced CRC treated with fluoropyrimidines in combination with either oxali-platin (77%) or irinotecan (18%), the most

Ngày tải lên: 14/10/2020, 13:27

... treatment-refractory patients with advanced solid tumours In this preplanned subanalysis, the effect of nintedanib on the tumour vasculature, along with efficacy and safety, was assessed in 30 patients with ... patients with colorectal cancer (CRC) Methods: Patients with advanced CRC who had failed conventional treatment, or for whom no therapy of proven efficacy existed, were treated with nintedanib ranging ... schedules (once- vs twice-daily) of nintedanib Results Patients A total of 30 patients with advanced, non-resectable and/or metastatic CRC were treated with increasing doses of nintedanib once- (n =

Ngày tải lên: 14/10/2020, 13:28

... p53 as biomarkers in patients with advanced pancreatic cancer has not yet been defined Methods: Within the phase III study AIO-PK0104 281 patients with advanced pancreatic cancer received an erlotinib-based ... observed for patients with a regular p53 expression compared to patients with a complete loss of p53 Conclusion: pERK expression may have an impact on OS in erlotinib-treated patients with advanced ... + erlotinib followed by gemcitabine in patients with advanced disease, patients with a KRAS wildtype may have a prolonged survival compared to patients with KRAS exon 2 mutations [7] Other groups

Ngày tải lên: 14/10/2020, 15:03

... cancer, Metastasis, Outcome, GEM, EDNRA Background Bladder cancer is the 4th most common cancer in men and the 11th most common cancer in women [1] Patients with non-muscle-invasive bladder cancer ... significantly associated with decreased cancer-specific survival Conclusions: GEM and EDNRA were identified as promising prognostic markers for patients with advanced bladder cancer The clinical relevance ... cystectomized patients was retrieved A total of 69 patients were included in the analysis, after exclusion of all patients without reported lymph node status, and all node negative patients without

Ngày tải lên: 14/10/2020, 15:12

... with patients with advanced cancer and their caregivers Oncologists receive a copy of the DVD to keep and receive a 1-page summary of evidence-based guidelines for communication in advanced cancer ... 12 months, thereby excluding patients with potentially curable Stage III cancers, such as Stage IIIc testicular cancer or Stage IIIa colon cancer Hoerger et al BMC Cancer 2013, 13:188 http://www.biomedcentral.com/1471-2407/13/188 ... introduced by the low prevalence of breast cancer in men and the potential that breast cancer patients may be more “activated” than patients with other cancers For each site/focus combination in

Ngày tải lên: 05/11/2020, 06:14

... remission in 70-80% patients but it fails to get rid of any residual microscopic disease As a consequence, within few months these patients return with recurrent cancer[ 1] In most cases, patients present ... Epithelial ovarian cancer is the fourth major cause of cancer morbidity and mortality in women In spite of recent advances, the prognosis for a woman diagnosed with advanced- stage ovarian cancer has ... ascites of patients with advanced- stage ovarian cancer (As2, As4, As9, As11) were prepared and loaded on 10% SDS-PAGE gels as described in the Methods and Material Blots were probed with mouse...

Ngày tải lên: 20/06/2014, 07:20

... Inpatients Outpatients Healthy Controls Inpatients Outpatients Healthy Controls Figure PSQI-measured sleep quality differences between inpatients, outpatients and healthy controls Lung cancer patients ... circadian function among advanced lung cancer patients The primary goal of the study is to determine whether and how the circadian organization of cancer patients is affected by the cancer- bearing state ... cancer patients compared to population-based controls Wake Period Actigraphic Parameters All patients Sleep Period Population controls All patients By Site Population controls Inpatients Outpatients...

Ngày tải lên: 10/08/2014, 09:20

... report: Human studies (5 breast cancer, colorectal cancer) 34 Animal exposure (15 breast cancer, 19 colorectal cancer) 25 Human cell lines (15 breast cancer, 10 colorectal cancer) Combination [animal/cell ... interventions may help reduce cancer risks in the general population Breast Cancer According to the US National Cancer Institute (NCI), breast cancer is the most common cancer among women.46 In 2009, ... ratio (OR) of risk of breast cancer associated with alcohol consumption.52 13 Colorectal Cancer Of the estimated 75,590 men and 71,380 women diagnosed with colorectal cancer, 49,920 men and women...

Ngày tải lên: 14/02/2014, 21:20