game mechanics and dynamics in greater depth

... DNA such as knot-ting, catenation, and the definitions of linking number and supercoiling Itcontinues with an outline of continuum and discrete models of DNA elas-ticity, focusing on local energy ... molecule Since in a closed duplex DNA Lk is invariant, any change in T w, which maycome about as a result of binding of DNA to proteins (such as histones) or intercalating molecules, will induce ... corresponding opposite change in W r Alternatively, DNA mechanics tells us that if Lk is changed by cuttingand resealing of DNA strands, that change will be partitioned into a change in T w and a

Ngày tải lên: 11/06/2017, 20:28

... starting and ending nodes are both included in module , and are the numbers of interactions whose starting or ending nodes only, respectively, are included in module , and is the total number of interactions ... Chapter 4 shows my new findings in investigating changes of modularity and robustness by edge-removal mutations in signaling network Chapter 5 summarizes my main findings and also offered some ... both included in module , and are the numbers of interactions whose starting or ending nodes only, respectively, are included in module , and is the total number of interactions in the network Finally,

Ngày tải lên: 04/03/2019, 22:32

... Biomechanics: Mechanics and Design in Musculoskeletal Systems, by Donald L Bartel, Dwight T Davy, and Tony M Keaveny ISBN 0-13-008909-5 Solution Manual for Orthopaedic Biomechanics Mechanics and ... Biomechanics: Mechanics and Design in Musculoskeletal Systems, by Donald L Bartel, Dwight T Davy, and Tony M Keaveny ISBN 0-13-008909-5 Solution Manual for Orthopaedic Biomechanics Mechanics and ... Biomechanics: Mechanics and Design in Musculoskeletal Systems, by Donald L Bartel, Dwight T Davy, and Tony M Keaveny ISBN 0-13-008909-5 Solution Manual for Orthopaedic Biomechanics Mechanics and

Ngày tải lên: 21/08/2020, 09:45

... Dissertation INVESTIGATION ON MODULARITY AND DYNAMICS IN SIGNALING NETWORKS School of Electrical Engineering University of Ulsan TRUONG CONG DOAN November 2017 INVESTIGATION ON MODULARITY AND DYNAMICS IN ... friends and labmates They helped me a lot to be familiar with the life in Korea, and shared interesting things in the life and research With my Vietnamese friends, they also shared with me all sad and ... Truong Cong Doan was born in Nghe an province on August 05, 1980 and has been living in Hanoi since 1998, Vietnam He received the degree of bachelor in Applied Mathematics and Informatics (2002) from

Ngày tải lên: 08/02/2021, 13:20

... structures inside the metals, e.g., octahedral interstices in fcc and hcp, and tetrahedral interstices in bcc structures, and that higher diffusion barriers could be more relevant in fcc or hcp than in ... (TM) elements, is explored in some detail, pointing out the importance of relative position and the width of the 3d band in interaction with H(s) bonding and antibonding state We also mention ... behavior in different crystal structures of the Mg–H system An interesting insight in influence of Ti and Co impurity (10 wt.%) on the MgH2 rutile structure is presented in [72,91] In Figure

Ngày tải lên: 24/11/2022, 17:44

... game b) Complete-information & Incomplete-information games Complete information is the concept that each player in the game is aware of the sequence, strategies, and payoffs throughout gameplay ... each decision point Information: Information available at one identified moment of the game decision-making and results are formed accordingly Payoff: An amount showing as an element in the payoff ... Given this information, the players can plan accordingly based on the information to maximize their strategies and utility at the end of the game Incomplete Information game is a game where the

Ngày tải lên: 28/06/2025, 22:57

... amine dehydrogenase. This enzyme is especially interesting because it is fairly nonspecific in the substrates it will bind and catalyze. In particular, in the series benzylamine, dopamine, and ... valine changes protein dynamics, and it is this alteration, missing in the mutation at position 93, which in turn changes tunneling dynamics. (We note the recent experimental results from Klinman’s ... starting point for any dynamics study of a protein. Second, there are a number of mutants of HLADH, which allow detailed study of the influence of protein composition on protein dynamics, and how dynamics

Ngày tải lên: 31/03/2014, 23:20

... stable in Japan, decreasing in Germany, and first increasing and then creasing in Sweden Waste paper recycling is highest in Germany and Japan, intermediate in the United States and lowest in Sweden ... dioxins (Reinstaller, 2005), and the increase in the use of re-cycled paper as an input in the paper production process Although less spectacular and more gradually, the pulp and paper industry in ... change in the pulp and paper sector in more detail Trang 9exam-2 Technical and Environmental Innovation In the pulp and paper industry, as in other industries, it is useful to make a distinction

Ngày tải lên: 01/04/2014, 00:20

... non-cooperative games independ-• cooperative games and their place within the literature of games • incentive and the implementation of a collective decision in theoretic modeling game-• team games and the ... hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers. British Library Cataloguing in Publication ... studyingnon-cooperative games, which culminated in his bargaining approach tocooperation (1953) According to this view, Nash obviously appears as aturning point in the recent history of game

Ngày tải lên: 08/04/2014, 12:15

... and INM-subdomain in interphase and mitosis ER /nuclear membranes contain a typical chromatin binding INM protein (dots) and are in close proximity to chromatin In interphase binding ... dephosphorylation and INM proteins diffusing in ER cisternae that come in contact with chromatin are retained and thus reform the INM subdomain by attaching... the lamina and/ or the INM In interphase ... 16 Studying Nuclear Envelope Protein Dynamics 17 Dynamics in Interphase 17 Chromosomes Do not Move Much in Interphase 21 Dynamics in Mitosis 21 INM Proteins: Switching Retention Off and Back

Ngày tải lên: 11/04/2014, 10:00

... boundary ∂Ω, we play the following game Let a mass point move freely inside Ω, starting at some initial point on the boundary with some initial direction pointing into Ω When the “billiard ball” ... the fixed point In general, it does notgive any information about the dynamics away from the fixed point The main result in this context introduces the minimal action as a plectically invariant ... constructed in [2, 19, 63, 87]) into a common frame-work 2 Fixed points and invariant tori We consider a symplectic diffeomorphism in a neighbourhood of an elliptic fixed point in R2 If the fixed point

Ngày tải lên: 24/04/2014, 16:50

... dopaminergic system [19], resulting in PD symptoms, including reduced stride length [14] and posture disturbances in mice [20] One common mouse model of HD is obtained by repeatedly administering ... gait cycle timing in Parkinson's disease and Huntington's disease Mov Disord 1998, 13:428-437 Blin O, Ferrandez AM, Serratrice G: Quantitative analysis of gait in Parkinson patients: increased variability ... impaired in patients with Parkinson's disease (PD) and Huntington's disease (HD), but gait dynamics in mouse models of PD and HD have not been described Here we quantified temporal and spatial indices

Ngày tải lên: 19/06/2014, 10:20

... Mechanics and Meaning in Architecture This page intentionally left blank Mechanics and Meaning in Architecture Lance La Vine M IN NE SO TA University of Minnesota Press Minneapolis ... mechanics and meaning Architecture's Loss of a Distinct Technological Voice 17 The rise of engineering in the building professions; architectural incorporation of engineering constructs; a case in point; ... they, in and of themselves, provide an inclusive and satisfying definition of the role of technology in architectural design Architectural drawings increase the scope of this definition by linking...

Ngày tải lên: 29/04/2014, 15:43

... of RIα showing an N-terminal dimerization/docking domain (D/D) (gray hashed box) connected by a linker to two tandem cAMP-binding domains, CNB-A and CNB-B in green The linker contains a PKA pseudosubstrate ... disordered linker region The proximal cAMPbinding domain is referred to as the cAMP binding A domain and the distal domain is the cAMP binding B domain The C-subunit on the other hand is a globular ... binding domains The mammalian RIα isoform is modular and extended proteins having a very similar domain organization with an N-terminal dimerization domain connected to two cAMP binding domains...

Ngày tải lên: 10/09/2015, 08:35

... conductivity and strain hardening [12, 13] Currently, there Introduction is a considerable research effort in understanding and designing nanotwinned metals for future engineering applications Twins are ... studies indicate the ultrahigh strength of nanotwinned crystalline metals is related to nanotwin induced interface strengthening The increase in strength with decreasing grain size/twin spacing is ... the intersection of K1 and K2 is the shearing plane The two directions η1 and η2 , lying in K1 and K2 , are perpendicular to the line of intersection of K1 and K2 They are known as the twinning...

Ngày tải lên: 11/09/2015, 10:03

... the binding ligands and the host protein The structural changes in some proteins regulate the interaction between ligands and protein through induced fit and allosteric effects [2,3] The “induced ... MAINTAINED, throughout NOT MAINTAINED; rather motions created, burying surface Motion at interface Parallel to plane of interface Perpendicular to interface (shear) Mainchain packing Constrained ... occurring predominantly by a hinge or a shear mechanism, or none of them In the smaller intra-domain protein motions, hinge and shear mechanism are also involved in the collective motion, when individual...

Ngày tải lên: 17/09/2015, 17:17

... Option because other options involve them in many other activities including harvesting, cutting roots and drying and collecting cassava chips The difference in margin is not big enough for them ... and global trading systems Priority agendas include development of a comprehensive strategy for agriculture, increasing public investment in the sector, encouraging and facilitating private involvement ... involvement in agriculture and agro-processing, expanding extension services and improving basic infrastructure Priorities for agricultural export development are improving and building up a regulatory...

Ngày tải lên: 21/02/2014, 04:20

... 10–30 glutamine residues in healthy individuals, whereas they are expanded to more than 40 repeats in patients In the polyQ diseases, inclusions containing polyQexpanded proteins are found in the ... ALS-linked SOD1 in vivo Conclusions and perspectives We reviewed the dynamics and toxicity of misfolded proteins (including polyQ-expanded proteins and ALSlinked SOD1) in living cells, with a particular ... sensitivity level using a dual-color system, and direct interaction between polyQ-expanded Huntingtin (Huntingtin-Q53) and the molecular chaperone CCT was detected using single-molecule FRET...

Ngày tải lên: 06/03/2014, 09:22

... Hastings and Springer (1994); b and c, Blum (1989); d, Springer and Williams (1994); e, Blum (1989) and Springer and Williams (1994); f, Winterbottom (1986), Springer (1988) Blum (1989), and Springer ... 36 Wainwrightand Bellwood prominently in this field, including anatomical and mechanical studies of the muscle-skeleton systems involved in feeding (Tchernavin, 1953; Alexander, 1967; Gosline, ... Springer and Williams (1994); g, h, and i, Indo-Australian Archipelago (see text); j and k, Springer (1988) and Blum (1989); 1, Springer (1982); m and n, Blum (1989); o and p, Hastings and Springer...

Ngày tải lên: 06/03/2014, 18:21

... the protein during the docking to the binding site on the ribosome or other ligands Strikingly, the second most flexible part of the protein (if one does not take into account the N-terminal region ... implicated in stop codon recognition [5–14] The role of the middle (M) domain will be described in detail below The C domain of eRF1 interacts with the C domain of eRF3 [15–18], and the binding of ... yeast eRF1 in vivo [3], and of Es coli RF2 both in vivo and in vitro [31,32] For instance, GAQ mutants of both RF1 and RF2 are four to five orders of magnitude less efficient in the termination reaction...

Ngày tải lên: 07/03/2014, 05:20