... Public Health (FOPH) and the National Institute of Cancer Epidemiology and Registration ( www.nicer.org ). Availability of data and materials The datasets generated and/or analysed during the ... Western Australia, Perth, Western Australia, Australia.3Division of Paediatric Haematology and Oncology, Department of Paediatrics, Inselspital, University of Bern, Bern, Switzerland 4 Pediatric Haematology-Oncology ... structures and farming practices and the balance between pesticide exposure and other exposures may differ in Switzerland from other countries Swiss farms are smaller on average (mean = 17.8 ha in 2010)
Ngày tải lên: 22/09/2020, 23:18
... soluble in water and ethanol and almost insoluble in acetic anhydride, ether and chloroform; melting point: about 250° C Epidural, conduction and spinal anaesthesias Amide type mepivacaine hydrochloride ... in paracervical block-plasma levels and changes in maternal and foetal acid-base balance Br J Anaesth 41:603–608 28) Matouskova A, Hanson B (1979) Continuous mini-infusion of bupivacaine ... in ether; melting point: 76–79° C. Epidural, conduction, infiltration, topical and spinal anaesthesias, ventricular arrhythmia 378 379Local anaesthetics Reagents and their preparation • Cacaine
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 45) pdf
... poison-ing cases, convulsion, facial edema and cyanosis were characteristic, and edemas of the epiglot-tis and vocal folds were observed in all cases [3] In this chapter, a method for GC/MS analysis ... uid was dark), and activated charcoal and Nifl ec® (2 L aqueous solution containing 2.93 g NaCl, 1.485 g KCl, 3.37 g NaHCO3 and 11.37 g Na2SO4) were administered orally At night of the 1st day ... p-phe-nylenediamine (1.6 g), had provoked the swelling of the face and neck, upper-abdominal pain, vomiting and acute renal failure (acute necrosis of urinary tubules), but had been able to sur-vive In
Ngày tải lên: 24/12/2013, 18:15
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 1) doc
... Drugs and Poisons in Humans A Handbook of Practical Analysis Osamu Suzuki and Kanako Watanabe Drugs and Poisons in Humans A Handbook of Practical Analysis With 236 Figures and 90 Tables 123 ... Chiba Nariaki TAKAYAMA Forensic Science Laboratory, Ishikawa Prefectural Police Headquarters, Kanazawa Tatsunori TAKAYASU Forensic and Social Environmental Medicine, Graduate School of Medical ... be taken into mind that a jelly containing a local anaesthetic had been applied to the catheter; urine is usually contaminated by such a drug Also for urine, the samplings according to time intervals
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 5) doc
... benzodiazepines, cocaine metabolites, amphetamines, a cannabinoid metabolite, opiates, phencyclidine and tricyclic antidepressants in only about 10 min Some similar kits are being sold in U.S.A and ... integration and data processing For analysis of inorganic anions and cations, anion and cation exchanger columns are used, respec-tively Since the change in electric conductivity caused by a target inorganic ... not smaller than that of Na can be easily analyzed qualitatively and quantitatively; the method is very suitable for elemental analysis of inorganic and metal compounds Th e advantage of this method
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 51) doc
... benzoylmesaco- nine, benzoylhypaconine, 14-anisoylaconine, aconine, mesaconine and hypaconine were donated by Tsumura (Tokyo, Japan). Benzoylaconine and aconine can be obtained also Structures of Aconitum ... elongation and torsades de pointes were observed. Transfusion, gastrolavage and administration of activated charcoal and a purgative were performed. For the arrythmias, lidocaine and disopyramide ... pre- sented. Reagents and their preparation • Aconitine was purchased from Sigma (St. Louis, MO, USA); mesaconitine and hypaconi- tine from Kishida Kagaku (Osaka, Japan). Jesaconitine, benzoylaconine,
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 52) docx
... Japan, because a very similar edible species Rhodophyllus crassipes is available and grows at similar locations Th e poisoning symptoms are vomiting, diarrhea and abdominal pain appearing 30 min–3 ... to be amanitin (> Figure 2.4) or phalloidin (> Figure 2.5) Th e amanitin is subdivided into α-, β- and γ-amanitins In Japan, Amanita virosa and Amanita verna glow generally, while in Europe ... and hallucinations (latent period, 20 min–2 h; Amanita pantherina, Psilocybe argentipes and others) • Th ose which irritate the gastrointestinal tract and provoke symptoms, such as abdominal
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 53) pptx
... methanol containing 0.5 % acetic acid and transferred to a small glass vial with a Tefl on cap, and again evaporated to dryness under reduced pressurei viii A 10-µL aliquot of dimethylformamide and ... victim was found dead in an automobile in a public park Th e cases Nos 3 and 4 were treated as unnatural death In other cases, all patients recovered aft er being admitted in hospitals In Cases ... Fugu niphobles in a large amount, was poisoned by eating its liver and died just aft er arrival at a hospital In Case No 3, the victim was found dead in a ship on ocean navigation In Case No 4, the
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 55) doc
... nicotine and conitine. HPLC analysis of nicotine and cotinine in blood and urine Reagents and their preparation • e standard solutions of nicotine and cotinine, and spiked serum specimens are ... [17]. In animal experiments using male Poisoning cases, and toxic and fatal concentrations 506 Nicotine and cotinine Sprague-Dawley rats with single oral administration each of tobacco exudates ... solutions are presented. GC/MS analysis of nicotine and cotinine in blood and urine Reagents and their preparation • Nicotine and cotinine (Sigma, St. Louis, MO, USA and other manufacturers) are dissolved
Ngày tải lên: 22/01/2014, 00:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 9) ppt
... each RI value, the same GC conditions and the n-alkane standards are adopted for the GC/MS analysis Analysis of chemical warfare agents by thermal desorption GC A gas-adsorbed sampleu obtained ... Trang 1© Springer-Verlag Berlin Heidelberg 2005 I.9 Analysis of chemical warfare agents and their related In this chapter, various analytical methods of chemical warfare agents and related ... mg) to avoid formations of organic alkali salts or organic acid salts, before condensation or evaporation car-Many of chemical warfare agents are easily hydrolyzed; in the practical analysis,
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 10) pdf
... Met-Hb and no chang- es in COHb and total Hb can be achieved; the storage with shading at –80 is most desirable. GC analysis See [4]. Reagents and their preparation • Solution of saponin and potassium ... isobestic point around 532 nm and the absorbance maximum around 558 nm appear; the exact wavelengths are re-examined for both points and small shi s of their wavelengths according to instrumental conditions ... (A 532 and A 558 ) are read against distilled water in another cuvette as a blank. vi. e percentage of HbCO can be calculated by the following equation: COHb %=(2.44–A 558 /A 532 ) × 67 Assessment
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 11) ppt
... death cases Notes a) Kawanishi et al [20] analyzed thiosulfate in urine and plasma of 5 healthy subjects; thio-sulfate concentrations in urine and plasma were 31.2 µmol/24 h (0.0288 µmol/mL) and ... glutathione copper into glutathione at a glutathione-refi nery factory [9], and in which one subject had died of poisoning by volcano gas fl owing backward into an oil-separating tank at a geothermal ... headspace method, the H2S gas in the head-space is decomposed according to heating temperature and time, resulting in variation in data obtained However, HS is relatively stable in the acetone
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 12) docx
... glycosides in the stomach In the tropical areas, it is also contained in cassaba; its poisoning by ingesting a large amount of cassaba is being a problem for health HCN can be produced during imperfect ... nitrogen-contain-ing compounds; it is also included in cigarette smoke and gases produced in a fi re Th ere are many kinds of qualitative and quantitative methods for analysis of cyanide in wide fi ... ecting the great needs of its analysis Th e Japanese Industrial Standard (JIS) standard-ized a method of cyanide analysis for factory waste water [1] Nonomura [2] published a review for analytical
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 13) pdf
... e acute methanol poisoning symptoms are vertigo, debility feeling, headache, nausea, vomiting and others; in rare cases, visual disturbance appears at an early stage Th ese symptoms usually appear ... cap and mixed well ii Th e vial is incubated at 35°C for 15 min with mixing gently several times Aft er the incuba-tion, about 0.6 mL of the headspace vapor is drawn into a gastight syringe and ... require any organic solvent and that the extraction, condensation and injection into GC can be achieved with one-step procedure Especially in the headspace SPME, the impurity peaks appearing in a GC
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 59) pptx
... cartridges and wide-bore capillary gas chromatography of organoposphate pesticides. Forensic Sci Int 41:67–72 2) Hayasaka M, Kawabata S, Haba A et al. (1994) Analysis of malathion metabolites in biological ... they are well separated. GC and GC/MS analysis 540 Organophosphorus pesticides Metabolic pathways for malathion in mammals. ⊡ Figure 2.2 TIC and gas chromatogram for malathion and its metabolites ... sensitivity and speci city. e metabolites are usually highly polar, and thus need derivatiza- tions for GC detection. GC and GC/MS analysis Materials and preparation • Standard compounds:
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 60) ppt
... than paraquat and are easily obtainable; they, thus, have come into wide use since 1980 Th e PAAHs include glufosinate (GLUF), glyphosate (GLYP) and biala-phos (BIAL) In Japan, there are many ... that any plot below line A indicated a mild case, and one above line B a severe case; in the area between lines A and B mild and severe cases were mixed Both GLUF and coexisting surfactant seem ... GLYP, AMPA and APPA (IS).⊡ Figure 3.2 Trang 5TIC (upper panel) and SIM chromatograms (lower panel) obtained by GC/MS for t-BDMS derivatives of GLUF, MPPA, GLYP, AMPA and APPA (IS) (10 ng each on-column).
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 61) docx
... from Wako Pure Chemical Industries, Ltd., Osaka, Japan. A standard mixture of seven N-methylcarbamate pesticides can be obtained from Kanto Chemicals (Tokyo, Japan) b . Carbofuran, carbaryl and ... than that of carbofuran; the both compounds are metabolized into a highly toxic metabolite carbofuran in mammals. In furathiocarb and benfuracarb poisoning cases, carbofuran should be analyzed ... toxicities are shown in > Table 4.1 [1]. Carbamate pesticides are generally classi ed into N-methylcarbamate insecticides and N-allylcarbamate herbicides in view of their chemical structures and
Ngày tải lên: 26/01/2014, 18:20
Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 62) ppt
... separetely detect paraquat and diquat, when specimens obtained from a victim of poisoning by a paraquat-containing product are analyzed For simultaneous analysis of paraquat and diquat, the methods ... ection points at about 396 and 403 nm for paraquat and at 437, 445, 454 and 464 nm for diquat Th e quantitation is made with ampli-tudes measurable between 396 and 403 nm for paraquat and between ... Zero-order and second-derivative spectra after deproteinization and reduction 1: blank plasma; 2: diquat-spiked plasma; 3: paraquat-spiked plasma; 4: paraquat plus diquat-spiked plasma The concentration
Ngày tải lên: 26/01/2014, 18:20
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)
... Main metabolic pathways of morphine, heroin and codeine The thick and thin arrows show the main and minor metabolic pathways, respectively ⊡ Figure 3.1 196 Morphine and its analogues GC and ... Hasegawa M, Maseda C, Kagawa M et al (1992) Morphine and codeine being contained in poppy seeds and poppy seed-containing foods Eisei Kagaku 38:192–195 (in Japanese with an English abstract) 11) ... morphine, codeine and tetrahydropapaveroline in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible biosynthetic pathway of morphine from L-3,4-dihydroxyphenylalanine...
Ngày tải lên: 24/10/2013, 19:15
Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)
... 285, 290 alternative specimens Amanita neoovoidea 480 Amanita pantherina 469 Amanita phalloides 469 Amanita verna 469, 474 Amanita virosa 469, 473 amanitin 473, 477, 479 amido-type local anesthetic ... 635 inorganic nitrite 649 inorganic poisons 637 interface 40 International Normalized Ratio 605 intratracheal contents 168 intratracheal gas 161, 162 in vitro interval 218 iodoplatinate reagent ... absorbance of cuvette B at 630 nm is read using cuvette A as reference, and this reading is A1 After allowing cuvette D to stand for 10 min, the absorbance at 630 nm is read using cuvette C as...
Ngày tải lên: 24/10/2013, 19:15