... convert allergen molecule in to hypoallergenic derivatives through destruction or reorientation of IgE epitopes, such allergen derivatives may act as potent hypoallergenic vaccines for immunotherapy ... The allergens from grass pollen are amongst the most potent and frequent elicitors of allergic disease Phl p is a timothy grass pollen allergen with a molecular weight of 10 959 kDa Phl p crystallizes ... unlike other thiamine synthesizing organisms, use bifunctional enzymes with both HMP-P kinase and TMP synthase activities These unique plant enzymes had not been structurally or kinetically characterized...
Ngày tải lên: 16/03/2014, 10:20
... minutes, including instructions and other preliminary activities Results The left part of Fig illustrates the outcome of Exp A Older subjects performed generally less well than younger ones, in all ... speed, and all succeeded in not touching the obstacles We quantified their performance as mean walking speed from the last footfall before the second obstacle until the first footfall after the ... the registered task may not reflect ARD, but rather seniors' higher priority for the non-registered task [26] Other authors avoided this design flaw, but yielded discrepant results: some observed...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo y học: "Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression" doc
... the level of integration can completely abrogate HIV-1 replication, but may still allow expression of early viral proteins, including Nef, from episomes in the first round of infection [28,29] ... and one hCCR5-single-transgenic rat were challenged intravenously with HIV-1YU-2 On day 4, all animals were sacrificed and spleens removed The levels of all three HIV-1 cDNA species were quantified ... observations argue that rat-derived cells are intrinsically more permissive for these early post-entry steps in HIV-1 infection than cells from other small animals, although this difference is not understood...
Ngày tải lên: 13/08/2014, 05:22
Tài liệu mở rộng quản trị mạng IP Packet Header Fields
... Numbers" [9] Header Checksum: 16 bits A checksum on the header only Since some header fields change (e.g., time to live), this is recomputed and verified at each point that the internet header is ... selected to allow a reasonable sized data block to be transmitted in addition to the required header information For example, this size allows a data block of 512 octets plus 64 header octets ... header octets to fit in a datagram The maximal internet header is 60 octets, and a typical internet header is 20 octets, allowing a margin for headers of higher level protocols Identification: 16...
Ngày tải lên: 13/11/2012, 11:22
Tài liệu LoopStar® 714 and LoopStar® 718 Extend Ethernet Services to All Customers Over Readily Available T1/E1 Facilities docx
... high-margin Ethernet services to all of their customers, no matter where they are located on the network Core LS 750 Switch/Router T1/E1 LS 718 VoIP PBX LS 714 Ethernet 01/06 • Bonded T1/E1s Ethernet ... restoration of failed links • Compact design makes it simple to install at the customer premise, either as a wall-mounted or rack-mounted unit • Allow for easy access to configure or disable access and ... LoopStar® 718 Extend Ethernet Services to All Customers Over Readily Available T1/E1 Facilities Benefits 102157AE LoopStar® 714 and LoopStar® 718 • Cost-effective approach to deliver Ethernet services...
Ngày tải lên: 09/12/2013, 17:15
08 TAYLOR MODELS AND OTHER VALIDATED FUNCTIONAL INCLUDING METHOD MAKINO & m BERZ
... the fact known to scientists of all backgrounds that locally, smooth functions can be well represented by their Taylor expansion The only, but of course crucially important, augmentation lies ... It is apparent that now, an evaluation with a reasonably small interval including will provide a much better result, since the contributions of the various higher orders decrease in importance, ... accounting for the approximation error TAYLOR MODELS AND OTHER VALIDATED 381 Over suitably small domains, the polynomial representation is naturally free of most of the dependency problem that the...
Ngày tải lên: 12/01/2014, 21:47
Tài liệu ORGANIZING FOR CHANGE PROFESSION Integrating architectural thinking in other fields doc
... composers and managers, respectively More specifically, in aligning form and matter, they call for a critical balance between generally following and occasionally breaking the rules.18< Because specifying ... and radically so – over this same length of time In other words, we are confronted today by the paradox that the slowness of architecture has been left in the dust by the changes that all political ... with this phenomenon – massively calls into question one of architecture’s most elemental concepts: namely, either to bring people together physically or to physically separate them Isn’t it typical...
Ngày tải lên: 18/02/2014, 18:20
Apex Clearing Corp. All Mutual Funds: Data as of Jan 4th 2013, but is subject to change ppt
... END 1000 ALLIANZ NFJ ALL CAP VALUE CLASS D PNEBX 50 1000 4:00 PM ALLIANZ GLOBAL INVESTORS SOLUTIONS GROWTH ALLOCATID ARTCX Y 1000 ALLIANZ GLOBAL INVESTORS SOLUTIONS GROWTH ALLOCATIC AGRAX ALLIANZ ... N/A ALLIANCE BERNSTEIN Y 2500 200 2500 ALLIANCE BERNSTEIN SMALL CAP GROWTH CLASS B B 01877E206 QUABX BACK END NON-NTF N/A ALLIANCE BERNSTEIN N 2500 200 2500 4:00 PM ALLIANCE BERNSTEIN SMALL CAP ... END NON-NTF N/A ALLIANZ N 1000 50 1000 4:00 PM NON-NTF N/A ALLIANZ 50 ALLIANZ GLOBAL INVESTORS SOLUTIONS CORE ALLOCATION C 01900C755 PALCX BACK END ALLIANZ Y 4:00 PM 1000 4:00 PM ALLIANZ GLOBAL...
Ngày tải lên: 07/03/2014, 08:20
the know-it-all’s guide to life how to climb mount everest, cure hiccups, live to 100, and dozens of other practical, unusual, or just plain fantastical things
... Cicero’s advice: “If all else fails, abuse the plaintiff.” How to decode Wall Street In the wake of all the bad press about Wall Street equity research analysts, you should know that all research is ... generally barred from working with nonunion actors) and union parts Although extras are usually well fed, there are few other perks Autograph seeking and photography on the set are verboten Bothering ... hair does not fall out, it is trickier for surgeon to properly and requires a real specialist Another surgical means of minimizing a bald spot is called “scalp reduction,” usually done in concert...
Ngày tải lên: 03/06/2014, 01:09
the blackwell guide to the philosophy of computing and information-(all, but no chp 10, 21, 22)
... usually less firm and clear in philosophy than in science, and hence more difficult to challenge, but also because, as we shall see better in section three, this is the context where a culturally ... status of the characteristic technology of our time, factually, rhetorically and even iconographically The computer presents itself as a culturally defining technology and has become a symbol of the ... etc.) that are logically and contextually (and hence sometimes fully) constrained and constantly challenged by the data that they need to accommodate and explain Historically, the evolution of...
Ngày tải lên: 05/06/2014, 11:27
APPLICATIONS OF MONTE CARLO METHODS IN BIOLOGY, MEDICINE AND OTHER FIELDS OF SCIENCE pps
... Medicine and Other Fields of Science Edited by Charles J Mode Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2011 InTech All chapters are Open Access articles distributed under ... it displays (see Figure ), but we keep throwing the dice without knowing about the significant change in the probability distribution Then, sample space, technically called “ensemble”, was modified, ... probability distribution for tossing the modified dice; and on the other hand, we actually did a number of tossing experiments of the damaged coin to estimate the probability distribution This is...
Ngày tải lên: 29/06/2014, 13:20
Trichoderma spp., including T. harzianum, T. viride, T. koningii, T. hamatum and other spp. pptx
... homokaryotic (nuclei are all genetically similar or identical) This, coupled with tight control of variation through genetic drift, allows these commercial strains to be genetically distinct and nonvariable ... collect in small wet masses Trichoderma species are strongly antagonistic to other fungi The exact nature of this relationship is still not clear, but it appears that they kill other fungi with ... used commercially in a variety of ways, including the following: Foods and textiles: Trichoderma spp are highly efficient producers of many extracellular enzymes They are used commercially for production...
Ngày tải lên: 02/07/2014, 20:21
Báo cáo toán học: "Against all Odds: The Amazing but Most True Story of Aviezri Fraenkel and his Special Favorite" pdf
... availability, all these and more were some of Aviezri’s remarkable contributions to these fields We are all so thankful and grateful to him for that They shall still bear fruit in old age; they shall be ... “queries and responses”, written essentially in Hebrew, that spans more than a thousand years and has its origin in almost all regions of the world, but especially in East (and some parts of West) ... were to look only at the picturesque gallery of its admirers, attackers and visitors, including Prime Ministers and ministers, ambassadors, diplomats and other high officials, scholars, rabbis,...
Ngày tải lên: 07/08/2014, 06:23
Báo cáo y học: " HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors" docx
... biochemically robust enzymatic activity that allows one to measure drug-susceptibility levels of the mutant RTs, it appeared that the aptamer-resistance mutations tend to target biologically crucial ... RTs First, we measured the breadth of cross-resistance to other anti-RT inhibitors, including several standard NRTIs and NNRTIs and otherDNA and RNA aptamers specific to HIV-1 RT Second, we have ... E478Q [36] showing no cleavage of the RNA:DNA duplex Unchallenged, polymerase-dependent cleavages Similar to challenged reactions, for unchallenged polymerase-dependent RNAse H reactions, a 30-nt...
Ngày tải lên: 10/08/2014, 05:20
Báo cáo y học: "Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors" pps
... sensitivity to 2G12 All other envelopes retain the critical N295 and N332 residues indicating that the determinants of 2G12 sensitivity and resistance are unclear but must include other determinants ... by bold script in Table This arbitrary designation allows for easy identification of these envelopes as grey symbols in subsequent figures All but one brain envelope conferred macrophage infection ... gp120:CD4 binding but not with inhibitors that prevent gp120, CCR5 interactions or gp41 conformational changes Intrapatient variation in sensitivity to b12, and CCR5 antagonists Although all but one of...
Ngày tải lên: 13/08/2014, 06:20
Báo cáo y học: "Background: Mood disorders including depression and bipolar disorders are a major cause of morbidity in childhood and adolescence, and hospitalizations for mood disorders are the leading diagnosis for all hospitalizations in general hospit
... probability-based sample of pediatric stays from all hospitals that contribute data to HCUP For each hospital, 10 percent of normal newborns and 80 percent of all other neonatal and pediatric stays are ... the underlying distribution of mood and mental health disorders, practice patterns, bed availability (including distribution of psychiatric hospitals), insurance policies, and other organizational ... Research Branch, National Institute of Mental Health, Bethesda, MD, USA Authors’ contributions All authors contributed to discussion and interpretation of data analysis, and writing and revisions...
Ngày tải lên: 13/08/2014, 18:22