endogenous programmed alveolar regression and regeneration

... treatment and 8-fold increase for TNF-α treatment relative to vehicle), dermal (14fold and 4-fold increase) and synovial (31-fold and 7-fold) fibroblasts (Figure 5) By contrast, classical T-helper-1 and ... expressed and mediates a wide range of responses to endogenous and exogenous glucocorticoids Thus, dysregulated GR signalling is likely to be an integral component of persistent inflammation, and previous ... supervised collection of tissue and generation of cells, and co-wrote MH developed initial hypothesis, supervised all cell analyses and co-wrote All authors read and approved the final manuscript...

Ngày tải lên: 09/08/2014, 08:22

... Computer and Information Science, University of Pennsylvania, Philadelphia, 1979 Kwasny, S C and Sondheimerl N K, Ungrammaticalily and Extra Grammaticality in Natural Language Understanding Systems ... isomorphic to the first output example above, except that Sender is replaced by Recipient and CC in the second and third parses respectively Again, this form of representation does not allow the System ... ambiguity as several complete parses gives Jt very little help in understanding a response of "June" from the user, a very natural .and likely one in the circumstances In essence, the parser has thrown...

Ngày tải lên: 31/03/2014, 17:20

... statistical analysis and drafted the first version of the manuscript CMdO organized and conducted the study, and has critically revised the manuscript AS supervised the entire study and critically ... disability, social disability and handicap Adolescents were asked to rate each of the 14 items on a 5-point ordinal scale coded 'never', 'hardly ever', 'occasionally', 'fairly often' and 'very often' The ... crossbite, crowding, impeded eruption, defects of cleft lip and palate as well as any craniofacial anomaly, Class II and Class III buccal occlusions, and hypodontia Only the highest scoring trait is used...

Ngày tải lên: 18/06/2014, 19:20

... AQLQ and SF-36 domain scores graphically and by looking at skewness and kurtosis Since AQLQ and SF-36 scores were skewed towards high scores and not distributed normally, we calculated medians and ... the AQLQ domain scores were found between and 2, and and 7, respectively, and when the SF-36 domain scores were found between and 10, and 90 and 100, respectively For internal consistency reliability, ... between 25% and 75% of the forced vital capacity *p = 0.01 and p < 0.05 compared to groups A and B, respectively; †p = 0.01 and p < 0.05 compared to groups A and B, respectively; ‡p < 0.01 and p

Ngày tải lên: 18/06/2014, 22:20

... viruses from maize and 51 in the viruses from sugarcane Two of these were deletion mutations (mutation 12 in E1-02 and mutation 33 in SC-E-02 and F10; Figures and respectively) and one was an insertion ... T→C transitions on the virion strand (the only strand that spends any appreciable time in a single stranded state) than on the complementary strand As the two strands are complementary, one need ... E2-01, K-MP-S) for the maize viruses and 18 (SC-E02) for the sugarcane viruses Besides three identical clone pairs (E5-01 and E5-02; E7-01 and E7-02; E3 and F7) all 20 remaining genomes were...

Ngày tải lên: 20/06/2014, 01:20

... parkinsonism, dystonia, and dyskinesia, and adverse-effect reporting to document weight gain and hypotension Values for systolic blood pressure, pulse, and weight were obtained at baseline and endpoint ... began with work by Fryback and colleagues on mapping between the SF-36 and the QWB [7] and have been extended by many others [8,9] A second approach, described by Brazier and colleagues, has been ... developed by Mohr and colleagues [16] For patients completing at least 50 weeks of treatment, the mean values of VAS and SG utility were calculated from the PANSS, and VAS and SG utility were...

Ngày tải lên: 20/06/2014, 15:20

... grade and necrosis: grade 0), and involves the margins of resection [8,9] A loco-regional assessment of tumoral extension by MRI Scan of the thigh, and a general assessment by thoracic and abdominal-CT-TAP-Scan ... aspect and evolution: welldifferentiated LPS (the most frequent), Myxoid LPS and\ or with round cells (40% of the LPS), and the anaplastic LPS, a rarer category of bad prognosis [3,8] Myxoid LPS and ... atypias and demonstrates a very low mitotic activity; the diagnosis is based on the particular aspect of vascularization on the one hand, and on the thorough detection of lipoblasts, on the other hand,...

Ngày tải lên: 09/08/2014, 04:21

... acquisition and analysis, performed the statistical analyses, and drafted the manuscript HL carried out the PLM data acquisition and analysis and helped draft the manuscript SM provided FTIR equipment and ... expertise and helped edit the manuscript DR assisted with the in vivo model and helped edit the manuscript KK conceived of and supervised the project, supervised all data collection and analysis, and ... flexion and loading was developed to simulate hand activities associated with the workplace [15] All procedures received prior approval and oversight from the University of California's Care and...

Ngày tải lên: 09/08/2014, 08:22

... T-MPCs, and adherent cells were obtained similarly Both T-MPCs and BM-MPCs were culture-expanded in basal medium at 37°C and 5% CO2 using T-150 Triple Flask (Nunc, Roskilde, Denmark), and medium ... including T-MPCs and BM-MPCs of the same passage maintained and cultured in expansion medium, and BM-MPCs cultured in adipogenic medium Morphological changes in BM-MPCs and T-MPCs and the formation ... negative for CD14, CD34, and CD45 and positive for CD29, CD44, and CD105 Bars = 20 μm (b) Flow cytometric analysis of T-MPCs and BM-MPCs CD14, CD34, CD45, CD105, CD73, and CD90 were detected by...

Ngày tải lên: 09/08/2014, 10:23

... study, and the acquisition, analysis and interpretation of the data, and participated in drafting the manuscript PSP contributed to the conception of the study, and acquisition, analysis and interpretation ... EMBASE, and PSYCINFO up to December 2008 A specific search strategy was developed for each database using the Cochrane methodological filter for randomised controlled trials and MESH keywords, and ... (AUC), sensitivity and specificity, and then used to compute the optimal cut-off value corresponding to the maximum sum of sensitivity and specificity Wilcoxon's signed rank test and Fisher's exact...

Ngày tải lên: 09/08/2014, 14:22

... tissue culture reagents were from GIBCO-BRL (Grand Island, NY) Kinase assay kits, U0126, and antibodies against phosphorylated and non-phosphorylated ERK1 and ERK2 were obtained from Cell Signalling ... kinases and NFκB We have examined the role of both the MAPK pathway and NFκB activation in BCG killing and nitric oxide production We report that both of these pathways are activated by BCG alone and ... containing ATP and a GST-Elk-1 fusion protein and allowed to incubate for The proteins were separated by SDSPAGE and phosphorylated Elk-1 was visualized by Western blot analysis Panel C: bands from...

Ngày tải lên: 12/08/2014, 14:20

... Zealand (NZ) Māori, Pacific Island and Caucasian samples Methods Rs3733591 was genotyped across gout patients (n=229, 232 and 327, for NZ Māori, Pacific Island and Caucasian, respectively) and ... controls (n=343, 174 and 638, for Māori, Pacific Island and Caucasian, respectively) Further Caucasian sample sets consisting of 67 cases and 4712 controls, and 153 cases and 6969 controls were ... participants Genotyping of New Zealand (NZ) sample sets of Māori (229 cases and 343 controls), Pacific Island (232 cases and 174 controls) and Caucasian (327 cases and 638 controls) was done (Table...

Ngày tải lên: 12/08/2014, 15:23

... contributions RD and TS designed the study and wrote the manuscript RD and AN carried out and interpreted the statistical analysis CL and MF participated in the design of the study and the data interpretation ... ESAT-6 and CFP-10 and a peptide from the TB antigenTB7.7 (Rv 2654, amino acids 38–55) The tubes were shaken and immediately incubated at 37°C for16– 24 hours, after which they were centrifuged and ... study using both the Mantoux and QFT-G test simultaneously in routine contact tracing, two main questions were addressed: (i) How well TST and QFT-G results correlate and what are the presumed reasons...

Ngày tải lên: 12/08/2014, 16:20

... human and mouse genome with Blockfinder and Syntenator Pairwise comparison of the human and mouse genome with Blockfinder and Syntenator Dark gray bars represent the proportion of man (HSA) and ... cells A(j, i) and T(j, i) according to Section "Score function" and Eqn (line 7) Subsequently the scores A(j, i) and A(pj,pi) are compared and cells with increasing score are stored as candidates ... and Δ denote the match score for two nodes and the gap penalty, respectively Gene order alignment Initially, all pairwise alignments between two POGs (e.g G1 and G2) are computed in forward and...

Ngày tải lên: 12/08/2014, 17:20

... digested with BseA1 and HindIII, purified and ligated into pBlue3’LTR The mutated subtype AE LTR was cloned from pBlue3’LTR into pLAI [57] using the XhoI and BglI restriction sites and verified by ... analysis and drafted the manuscript GP and MLvG have contributed to the experimental work BB has contributed to the study design and writing the manuscript REJ was responsible for the study design and ... input virus A sample of the cultures was split on day 2, and 14 and either TNFa or mock treated The cells were harvested 24 hours later and analyzed by FACS The percentage of CA-p24 positive cells...

Ngày tải lên: 13/08/2014, 01:21

... 264.7MuLVmix- and of 16 MoMuLV-induced tumors were non-lymphoid and diagnosed as erythroleukemia based on splenomegaly with a high frequency of erythroid cells and lack of reactivity with CD3 and PAX5 ... interests JMW, KYG and JWH conceived and designed the study JMW performed histopathological observations and carried out IHC studies LHE carried out focal IFA ZN performed cell culture and viral quantitation ... NCI, Frederick, MD and studied under NIAID Animal Care and Use Committee approved protocols and housing Mice were observed for to 12 months and necropsied when signs of splenomegaly, lymphadenopathy,...

Ngày tải lên: 13/08/2014, 06:20

... 7-10, and the fourth curve is composed of points 10, 11, 12, and back to point Points 1, 4, 7, and 10 are shared by adjacent curves In addition, Point and Point are always fixed at (1,0) and (0,0) ... lift and drag coefficients of stalled and unstalled airfoils in wind turbines and wind tunnels National Aeronautics and Space Administration, NASA/CR-2008-215434 (2008) National Oceanic and Atmospheric ... of 63.7, 67.7, and 69.4 for the root, midsection and the tip respectively at angles of attack 8, 7, and degrees Figure 10 shows a plot of the Cl /Cd for the designed airfoils and the S809 The...

Ngày tải lên: 09/09/2015, 10:17

... determine ligand specificity GDNF binds to GFRα1, NRTN binds to GFRα2, ARTN to GFRα3 and PSPN binds to GFRα4 In addition, NRTN and ARTN may crosstalk weakly with GFRα1 and GDNF with GFRα2 and GFRα3 ... and GNDF and the experiments were studied at 0, 10, 30, 60 and 180 mins respectively Western blotting showed that BCNU induces activation of MAP kinases (ERK1/2, JNK and p38) in both LN-229 and ... years of 30 and 34 and is 0.85 after the age of 6016 The incidence per 100,000 population of glioblastoma and astrocytoma rises from 0.2 and 0.5 in the under-14 age group to 4.5 and 1.7 respectively...

Ngày tải lên: 14/09/2015, 12:13