effects of pentacyclic triterpenes from olives on colon cancer

... Treatment of PBMC by different concentrations of flavonọds inhibited IL-4 production (73.26 ± 10 pg/mL , 30 µg/mL of flavonọds) and (89.90 ± 13.25 pg/mL, 50 µg/mL of flavonọds) compared to the control ... flavonọds extracts from A herba alba have an effect on the inhibition and the stimulation of the production of IL-12 and of IL-4, respectively This constitutes a way to switch the immune response ... doses of flavonọds (30, 40, 50 µg/ml) on IL-12 production in PBMC from ABD patients Similarly, the amounts of IL-4 released into supernatants of PBMC from controls subjects after pre-stimulation...

Ngày tải lên: 11/08/2014, 03:20

... is a differentiation in the impact and geographical distribution of the effects of pollutants on epiphytic lichens, ground vegeta-tion and the growth and crown condivegeta-tion of Scots pine due ... sensitivity of these plant groups to pollution The results are used to draw up recommendations for future monitoring activities aimed at evaluating the effects of the ongoing modernisation of the ... the lack of any direct measurements of the pollution impact Statistical analysis of ground vegetation and environmental variables The variation in species composition in the total dataset of 212...

Ngày tải lên: 17/02/2014, 22:20

... Chemopreventive Properties of Ginseng Compounds on Colon Cancer 393 Chong-Zhi Wang and Chun-Su Yuan Chapter 25 Effects of Pentacyclic Triterpenes from Olives on Colon Cancer 403 M Emília Juan ... activation of multiple caspases, arrest of cell cycle progression, and induction of differentiation The positive effect of this compound on other types of cancer like the hepatic has also been demonstrated ... transcriptional activity of NF-κB is a consequence of the phytochemicals antagonizing phosphorylation of IκB, the inhibitor of NF-κB, which is carried out by IκB kinases Constitutive activation of NFκB...

Ngày tải lên: 14/03/2014, 10:20

... and Regional Cancer Programs, Juravinski Cancer Centre, Hamilton, Ont., Canada 16 Faculty of Information and Media Studies, The University of Western Ontario, London, Ont., Canada § Corresponding ... University, Hamilton, Ont., Canada Primary Care, Cancer Care Ontario, Toronto, Ont., Canada 10 Prevention and Screening, Cancer Care Ontario, Toronto, Ont., Canada 11 Population Health Research, ... Hamilton, Ont., Canada Department of Family and Community Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ont., Canada Population Studies and Surveillance, Cancer Care Ontario, Toronto,...

Ngày tải lên: 10/08/2014, 11:20

... Foundation) Long-term Medical Conditions Alliance Lynn’s Bowel Cancer Campaign Macmillan Cancer Relief Marie Curie Cancer Care National Cancer Alliance National Council for Palliative Care Teenage Cancer ... Royal College of Surgeons NICE technology appraisal guidance 118 32 Royal Pharmaceutical Society Beating Bowel Cancer Cancer Voices Cancerbackup Bowel Cancer UK (Colon Cancer Concern) CORE (Digestive ... Professor John Cairns Professor of Health Economics, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine Professor Mike Campbell Statistician, University of...

Ngày tải lên: 14/02/2014, 22:20

... population In an analysis of the colon cancer data from the Health Professionals Follow-up Study, Platz et al [56] found that there was a 71% decrease in colon cancer risk when men with none of six ... for colon cancer than for breast cancer Most of the breast cancer studies only found a protective effect of folate among women who consumed alcohol (see Table 4) However, among women residents of ... Ammerman A, Sandler RS: Associations of micronutrients with colon cancer risk in African Americans and whites: results from the North Carolina Colon Cancer Study Cancer Epidemiol Biomarkers Prev...

Ngày tải lên: 06/03/2014, 02:21

... described as containing the nutritional equivalent of vegetables and fruits But the small amount of dried powder in such pills often contains only a small fraction of the levels contained in the ... ounces of beer, ounces of wine, or 1½ ounces of 80-proof distilled spirits (hard liquor) The combination of alcohol and tobacco increases the risk of some cancers far more than the effect of either ... saturated fat Coffee Does drinking coffee cause cancer? No The possible link between coffee and cancer of the pancreas, which got a lot of attention in the past, has not been confirmed by recent...

Ngày tải lên: 06/03/2014, 02:21

... determined the effects of 5-FU on colon cancer cells with endogenous low levels of miR-143 Therefore, we exposed HCT116 colon cancer cells to lm 5-FU, a clinically relevant concentration [23] that ... cellular proliferation via ERK5 ⁄ NF-jB signalling In turn, this may constitute a key event for colon cancer onset and progression miR-143 expression was evaluated in situ in mouse colonic epithelial ... function could potentially be improved via modulation of miRNAs that play a role in chemoresistance In the present study, we evaluated the role of miR-143 in the response of HCT116 colon cancer...

Ngày tải lên: 07/03/2014, 00:20

... esophageal cancer Fig Accumulated methylation of genes in the progression of esophageal cancer 3.2 Histone modification Histone modification (acetylation, methylation, phosphorylation, ubiquitylation, ... microenvironment for tumor development and progression through stimulation of cancer cell proliferation, induction of angiogenesis, cell mobility, inhibition of cell adhesion, and promotion of epithelial-mesenchymal ... 17 and 26 of histone H3 and residue of histone H4 Histone lysine methylation occurs on histones H3 and H4 and can be mono-, di- or trimethylated Similar to histone lysine methylation, arginine...

Ngày tải lên: 08/03/2014, 00:20

... on excess consumption of macronutrients, whereas the search for the nutritional causes of the typical cancers of developing countries has focussed on deficient intake of micronutrients Case-control ... Working Group on Diet and Cancer of the Committee on Medical Aspects of Food and Nutrition Policy) London: The Stationery Of ce, 1998 Armstrong B, Doll R Environmental factors and cancer incidence ... Diet, nutrition and cancer transit of food through the colon, thus diluting the gut contents and perhaps reducing the absorption of carcinogens by the colonic mucosa40 Fermentation of fibre (and...

Ngày tải lên: 15/03/2014, 01:20

... of Contents Nutrition, Exercise and Prostate Cancer Introduction Understanding the Links Between Nutrition, Exercise, and Prostate Cancer Effects of Oxidation and Inflammation The Contribution ... strong contributors to the development and progression of prostate cancer Effects of Oxidation and Inflammation Oxygen is essential to life, but the chemistry of oxygen and oxidation drives cancer ... providing optimum nutrition for the prevention of chronic diseases through improved cellular nutrition This is an area of continuing controversy among opinion leaders in nutritional science In fact,...

Ngày tải lên: 22/03/2014, 16:21

... alterations occurring at the key transition from hyperplasia to dysplasia include loss of expression of MLH1 in group CRC and loss of expression of MGMT and ⁄ or aberrant expression of p53 in ... 93; 9049–9054 16 Konishi M, Kikuchi-Yanoshita R, Tanaka K et al Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer Gastroenterology ... aggressive subset of colorectal cancer Br J Cancer 2001; 84; 232–236 69 Goel A, Arnold CN, Niedzwiecki D et al Characterization of sporadic colon cancer by patterns of genomic instability Cancer Res...

Ngày tải lên: 22/03/2014, 17:20

... the solution Microdissection of Histologic Sections Moskaluk Fig Example laser capture microdissection of colon cancer (A) Low power magnification of a histologic section of a human colon adenocarcinoma ... extraction of DNA for PCR-based typing from forensic material Biotechniques 10, 506–513 Epithelial Cell Isolation from Colon 15 Isolation of a Purified Epithelial Cell Population from Human Colon ... of localization of the putative tumor-supressor genes Consistent areas of gain or amplification would show location of the putative oncogenes involved in tumor initiation and progression In one...

Ngày tải lên: 10/04/2014, 22:22

... Exp:1 5of 33 Con:21 of 77 Exp:15 of 33 Con:29 of 77 Exp:14 of 80 Exp:17 of 80 Con:12 of 40 Jadad’s grades (year) Exp:18 of 73 Stage III ATC-BCG Con:31 of 109 Exp:16 of 73 [22] ATC Follow up Con:17 of ... Exp:1 6of 44 [23] ATV-NDV Stage I-IV Exp:20 of 44 Con:16 of 25 NO C Exp:1 2of 25 [24] 17-1 [25] Antibody ATC Stage III Con:48 of 76 Con:54 of 76 B Stage I-IV Exp:39 of 90 Con:146 of 257 Exp:50 of ... trials of ASI in suspected minimal residual CRC Ref ASI Stage of patient Overall Survival Disease-free Survival No of events/no of subjects [21] Con:35 of 109 Stage II Con:26 of 44 Con:28 of 44...

Ngày tải lên: 18/06/2014, 19:20

... translocation of bcatenin and altered the expression of E-cadherin and vimentin, in association with repression of the transcription factors snail1 and smad2/3 expression Knockdown of CK2a reversed ... protein expression, was affected Emodin increased the expression of E-cadherin, had no effect on the expression of b-catenin, and decreased the expression of vimentin in a concentration-dependent ... proliferation and colon formation in other CRC cell lines Moreover, for the first Zou et al Journal of Translational Medicine 2011, 9:97 http://www.translational-medicine.com/content/9/1/97 Page of 11...

Ngày tải lên: 18/06/2014, 19:20